Health products policy and standards
Our team provides authoritative guidance and standards on quality, safety and efficacy of health products and supports countries to formulate evidence-based policies and ensure good practice throughout the value chain.

International Nonproprietary Names Programme and Classification of Medical Products

International Nonproprietary Names (INN)

International Nonproprietary Names (INN) facilitate the identification of pharmaceutical substances or active pharmaceutical ingredients. Each INN is a unique name that is globally recognized and is public property. A nonproprietary name is also known as a generic name.

Mandate

WHO has a constitutional mandate to "develop, establish and promote international standards with respect to biological, pharmaceutical and similar products".

The World Health Organization collaborates closely with INN experts and national nomenclature committees to select a single name of worldwide acceptability for each active substance that is to be marketed as a pharmaceutical. To avoid confusion, which could jeopardize the safety of patients, trade-marks should neither be derived from INNs nor contain common stems used in INNs. The selection and publication of INNs falls under the responsibility of the EMP/RHT/TSN team of the INN Programme. 

Guidance on INN

Nonproprietary names are intended for use in pharmacopoeias, labelling, product information, advertising and other promotional material, drug regulation and scientific literature, and as a basis for product names, e.g. for generics. Their use is normally required by national or, as in the case of the European Community, by international legislation. As a result of ongoing collaboration, national names such as British Approved Names (BAN), Dénominations Communes Françaises (DCF), Japanese Adopted Names (JAN) and United States Adopted Names (USAN) are nowadays, with rare exceptions, identical to the INN.

Dr R. Balocco Mattavelli

World Health Organization
International Nonproprietary Names
(MHP/HPS/INN)
20 Avenue Appia
1211, Geneva 27
Switzerland
Tel: +41 22 791 1249
Fax: +41 22 791 4730


Publications

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INN Nomenclature Schema Icon

  Any change to the structure of a medicinal active substance will trigger a requirement for a new INN to be assigned. To highlight the close...

INN Bio Review
11 December 2023

INN Bio Review 2022

This document, first published on the website of the INN Programme in 2006, therefore presents an inventory of the policy decisions taken by the INN Expert...

INN Nomenclature Schema Icon

-tug for “unmodified immunoglobulins”The suffix -tug is used for monospecific full-length immunoglobulins with unmodified constant...

Last INN Consultation Executive Summary

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Icons INN Executive Summary

During the 77th INN Consultation, 252 INN requests were discussed, including:• 217 new INN requests, of which 146 were for biological substances•...

Icons INN Executive Summary

During the 76th INN Consultation, a total of 271 INN requests was discussed, including:• 238 new INN requests, including 149 for biological substances•...

Icons INN Executive Summary

During the 75th INN Consultation, a total of 259 INN requests was discussed, including:• 212 new INN requests, including 121 for biological substances•...

Last INN Recommended Lists

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INN Recommended List  Icon

Notice is hereby given that, in accordance with article 3 of the Procedure for the Selection ofRecommended International Nonproprietary Names for Pharmaceutical...

INN Recommended List  Icon

Notice is hereby given that, in accordance with article 3 of the Procedure for the Selection ofRecommended International Nonproprietary Names for Pharmaceutical...

INN Recommended List  Icon

Notice is hereby given that, in accordance with article 3 of the Procedure for the Selection ofRecommended International Nonproprietary Names for Pharmaceutical...

Last INN Proposed Lists

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INN Proposed List Icon
29 February 2024

INN Proposed List 130

Notice is hereby given that, in accordance with article 3 of the Procedure for the Selection of Recommended International Nonproprietary Names for Pharmaceutical...

INN Proposed List Icon

Notice is hereby given that, in accordance with article 3 of the Procedure for the Selection of Recommended International Nonproprietary Names for Pharmaceutical...

INN Proposed List Icon
19 January 2023

INN Proposed List 128

Notice is hereby given that, in accordance with article 3 of the Procedure for the Selection of Recommended International Nonproprietary Names for Pharmaceutical...