Although they have huge amount of great collection from various area, the building is complicated and not spatious, yet interesting to see many of nice collections

Worth a trip on its own, lots to interest most people inc some prehistoric artefacts, and some from the post war industrial heritage

An interesting place. But be prepared to be irritated if you like ordered sequential rooms exhibiting like near like. (Leave your irritability in the loo before you leave your hotel for the day's sightseeing?) The museum is spread over 7 buildings joined/linked together.
(There is also an overpass bridge crossing the road to the Kunsthalle Weishaupt, and you can buy a Kombi ticket to both (€12 adult); this ticket is flexible in the sense you can see one, go away for lunch, etc., and come back to see the other later in the day. I'd recommend not to do what I did which was go go to the Museum after lunch: better to go when you're fresher and give it more time. (The Kunsthalle Weishaupt is smallish.))
I suspect the interior designer has done a good job within the building(s) envelope provided them. But. There was no brochure with a floor plan in English; whether there was one in German, I don't know (and I suspected not). There are signs near the lifts and various odd spots that tell you what sections are on each floor. But since the joined-up complex is higgeldy-piggedy and there are similarly-branded sections on more than 1 floor, it's a challenge. I was helped at one point by an attendant who clearly surmized I could not decode the floor-plan sign I was looking at.
I decided the best thing to do was just wander and be surprised. That's how I stumbled on the special 'Walt Disney' exhibition, and also the Archeology section with its justly-famous 40000-year-old statuette of a man-lion. But i missed most of, or it didn't even reckon in my radar, that there was another special exhibition on. And i missed all of the collection of modern art called the Kurt Fried endowment, which the Museum is proud of.
When I was there, there were 2 special exhibitions, both included in the entry fee: 'Erwarten Sie Wunder' ('Expect wonder') (till October 15), and 'Walt Disney: Fantasien werden niemals alt') ('Fantasies never get old') (till September 17).