- Thomas Jane
- Frank Castle/The Punisher
- John Travolta
- Howard Saint
- Will Patton
- Quentin Glass
- Roy Scheider
- Frank Castle Sr.
- Laura Harring
- Livia Saint
- Ben Foster
- Dave
- Samantha Mathis
- Maria Castle
- James Carpinello
- John Saint/Bobby Saint
- Russell Andrews
- FBI Agent Jimmy Weeks
- Eddie Jemison
- Micky Duka
- John Pinette
- Bumpo
- Rebecca Romijn
- Joan
- Mark Collie
- Harry Heck
- Eduardo Yáñez
- Mike Toro
- Omar Avila
- Joe Toro
- Kevin Nash
- The Russian
- Marcus Johns
- Will Castle
- Jonathan Hensleigh
- Director, Screenwriter
- Avi Arad
- Co-Producer, Producer
- Gale Anne Hurd
- Producer
- Gerry Conway
- Writer
- Michael France
- Screenwriter
- Conrad W. Hall
- Cinematographer
- Steven Kemper
- Film Editing
- Pam Dixon
- Casting
- Michael Z. Hanan
- Production Design
- John Dexter
- Art Director
- Casey Hallenbeck
- Set Decoration
- Stan Lee
- Executive Producer
- Kevin Feige
- Executive Producer
- John H. Starke
- Executive Producer
- Amir Jacob Malin
- Executive Producer
