Following a distinguished career in public service, Senator Blunt left the U.S. Congress in January 2023 after representing Missouri for 12 years in the United States Senate and 14 years in the United States House of Representatives. Among his many achievements in the Congress, Senator Blunt is one of only two Americans in congressional history to be elected to a leadership position by his colleagues in both the House and the Senate.

During his 12 years in the Senate, Roy served as Chairman of the Senate Republican Policy Committee and Senate Rules Committee, and led the Presidential Inaugural Committees for the 45th and 46th Presidents of the United States. In addition, Senator Blunt was a key member of the Appropriations and Commerce Committees, and the Senate Select Committee on Intelligence. Within each of these policy areas Blunt led his colleagues to prioritize key issues for all Americans. As Chair of the Appropriations Subcommittee on Labor, Health and Human Services, and Education, Roy redirected resources and raised awareness of critical issues including increased funding for medical research. Blunt has been recognized by many health research advocates for his leadership during the COVID crisis and in the areas of Alzheimer's disease research and mental health. And the National Institute of Health (NIH) recently named their Center for Alzheimer's Disease and Related Dementia's in his honor. Prior to his tenure in Congress, Senator Blunt was a history teacher, a university president, a county official, and Missouri's Secretary of State.

Senator Blunt is actively involved in promoting and preserving the arts and history. He has served as a member of the Smithsonian Museum's Council of American Art, a member of the Kennedy Center Board of Trustees, and is President of the State Historical Society of Missouri.

Currently Senator Blunt serves as an Executive Fellow at the Bipartisan Policy Center in Washington D.C., Chair of the Advisory Board of the National Geospatial Agency of the U.S. Government, and serves on the Southwest Airlines and Tenet Healthcare Boards of Directors.