- Dwayne Johnson
- Jack Bruno
- AnnaSophia Robb
- Sara
- Alexander Ludwig
- Seth
- Carla Gugino
- Dr. Alex Friedman
- Ciarán Hinds
- Henry Burke
- Tom Everett Scott
- Matheson
- Chris Marquette
- Pope
- Billy Brown
- Carson
- Cheech Marin
- Eddie
- Garry Marshall
- Dr. Donald Harlan
- Kim Richards
- Tina
- Iake Eissinmann
- Sheriff Antony
- Tom Woodruff Jr.
- Siphon
- John Duff
- Frank
- Whitley Strieber
- Andy Fickman
- Director
- Matt Lopez
- Screenwriter
- Mark Bomback
- Screenwriter
- Andrew Gunn
- Producer
- Mario Iscovich
- Executive Producer
- Ann Marie Sanderlin
- Executive Producer
- Greg Gardiner
- Cinematographer
- David J. Bomba
- Production Design
- David Rennie
- Film Editing
- Genevieve Tyrrell
- Costume Design
- Trevor Rabin
- Original Music
- Randi Hiller
- Casting
- Sara Finn
- Casting
- John R. Jensen
- Art Director
- Patrick T. Cassidy
- Set Decoration
- Kara Lindstrom
- Set Decoration
