Talk:Erythromycin

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as This was at Erythromycins[edit]

as This was at Erythromycins, now redirected here. Charles Matthews 22:16, 12 Nov 2004 (UTC)

Eryfgthromycins are antibiotics used to treat infections caused by micro-organisms.These drugs are prescribed for many types of infections caused by bacteria: strep throat, pelvic inflammatory disease(PID), sinus infections, ear infections, pneumonia, tonsillitis, bronchitis, gonorrhea, pelvic inflammatory disease (PID), and urinary tract infections. sdfg

Edits[edit]

Who wrote this shit?! Erythromycin was developed in Australia by the Commonwealth Serum Laboratories, who registered it under the trademark ERYC in 1931! --RDF



I added a sentence from pyloric stenosis about a potential link in late pregnancy and infancy between erythromycin and pyloric stenosis. I'm not a medical expert and merely noticed that this was in contradiction to the statement in the introduction of this page to the effect that erythromycin is harmless in pregnancy. Someone with medical training and/or additional sources should review this addition and clarify the text. -- Linac1 — Preceding unsigned comment added by Linac1 (talkcontribs) 02:21, 14 March 2016 (UTC)

I've added a detail on allergic reactions, especially since I had an allergic reaction to this medication, went into anaphylactic shock and required emergency medical care, epinephrin injection, and long-term hospilization. This is backed up by consulting the Physicians' Desk Reference (Electronic Edition, Jan 2005 Revision) entry for Erythromycin, which states: "Allergic reactions ranging from urticaria to anaphylaxis have occurred." --Jeff


A search for erythrocin should not redirect me here... ugh! What is one to do when faced with a pre-lab which demands a MSDS for erythrocin b sodium, but also faced with no legitimate results on the entire world wide web (google-style)...

Having been prescribed this for the first time I am quite surprised the article doesn't mention that this antibiotic gives you really bad gas.


Gas...and the accompanying stomach ache.

I take Bayer's Ilosone, which is just a brand name for Erythromycin, because I am allergic to penicilin, but I have never had any stomach side effects. Is this documented??!?! —Preceding unsigned comment added by 162.80.36.13 (talk) 19:07, 9 December 2008 (UTC)

Function[edit]

The book "An introduction to genetic analysis" by Griffiths mentions that Erythromycin blocks the exit tunnel of the ribosome and thus interferes with elongation. Is this correct? —Preceding unsigned comment added by 80.108.103.172 (talk) 11:55, 22 June 2008 (UTC) Erythromycin binding site is located inside ribosome tunnel, but it does not fully overlap tunnel lumen when bound.Lamz (talk) 17:12, 14 May 2011 (UTC)

Half-Life[edit]

The main article says this antibiotic has a 2.5 hour half-life whereas the info table suggests it has a 1.5 hour half-life. Since I'm assuming they refer to the same meaning of half-life it would appear that one of them is wrong (although I have no idea which). -87.194.113.90 (talk) 11:40, 20 March 2008 (UTC)

Neither's wrong, but both are too definitive. Half-life depends on many things, including route of administration and host factors such as liver dysfunction. In normal patients after a 500 mg oral dose of enteric coated tablets, the elimination half-life was 2.0 +/- 0.7 hours. In normal patients after a 500 mg IV dose, the elimination half-life was 1.6 +/- 0.7 hours. In patients with alcoholic liver disease given a 500 mg oral dose of enteric coated tablets, the elimination half-life was 3.2 +/- 0.5 hours. [1]. So for erythromycin (and for that matter any drug) no single number should be cited as "the" half-life. - Nunh-huh 11:50, 20 March 2008 (UTC)

References[edit]

  1. ^ KW Hall, CH Nightingale, M Gibaldi, E Nelson, TR Bates, and AR DiSanto, "Pharmacokinetics of erythromycin in normal and alcoholic liver disease subjects", Journal of Clinical Pharmacology, 1982, 22: 321-325.

erythromycin estolate[edit]

if this is going to redirect here, then you need to have "estolate" somewhere in the article. —Preceding unsigned comment added by 128.125.28.128 (talk) 18:42, 26 September 2008 (UTC)

Availability[edit]

Erythromycin was once a $4 generic at Walmart, and available without prescription for veterinary use. Now (late 2012) it seems to have disappeared. Is it still on the market? Did it become very expensive for some reason? — Preceding unsigned comment added by 69.95.233.30 (talk) 00:36, 19 December 2012 (UTC)


July 2015 I just purchased at Walmart. Fortunately I have good insurance. If no, the prescription would have cost $543.41 They are 500 MG EC 40 pills. Dose 4 each day for 10 days. I'm am trying to find out why now so expensive and can't find anything. — Preceding unsigned comment added by 24.20.114.149 (talk) 22:10, 29 July 2015 (UTC)

Chemistry[edit]

The synthesis section discusses the total synthesis and uses parenthetical numbers to reference intermediates. This would be much clearer with a figure or something to make these numbers better than arbitrary... Jazzlw (talk) —Preceding undated comment added 06:42, 8 December 2015 (UTC)

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UCSF Foundations 2 2019, Group 1B Goals[edit]

- Find a citation for erythromycin's effect on combined oral contraceptives 
- Move some of the information located in "Adverse Effects" to "Interactions"
- Add citation for motilin receptor agonist under "Pharmacology - Mechanism of Action"
- Verify who first developed erythromycin  
- Verify potential use of IV formulation as an adjunct in endoscopy under "Adverse Effects", possibly move to "Medical Uses"

Megan.roberson (talk) 21:46, 30 July 2019 (UTC)

  • Please make sure your other group members assign themselves to this article.
  • Note that you can use * to make a bulleted list as well.
Health policy (talk) 03:46, 31 July 2019 (UTC)