I suggest you head out to the West Queen West neighbourhood - lots of great shops, restaurants, etc. out there. Basically it runs from Bathurst St. west to Dufferin St. The well known Graffiti Alley is just east of Bathurst.
https://www.blogto.com/westqueenwest/
Other neighbourhoods of interest, all easily reachable by transit, include Leslieville, Beaches, The Danforth, Ronscesvalles Village.
The St. Lawrence Market is just a couple of blocks east of the Royal York. Good place to pick up snacks, breakfast and lunch on the go.
http://www.stlawrencemarket.com/
On Saturdays, the Evergreen Brickworks market welcomes regional farmers.
https://www.evergreen.ca/evergreen-brick-works/markets-food/saturday-farmers-market/
BlogTO wil keep you up to date on events, restaurants, etc. happening in the city.
https://www.blogto.com/
If cycling or walking is of interest, Toronto has extensive trails along the waterfront and through the ravine networks. Rent bikes and try some. Or rent paddleboards and explore the waters around the Toronto islands.
https://www.toronto.ca/explore-enjoy/parks-gardens-beaches/