The Coyote vs. Acme cast is full of great actors and returning Looney Tunes icons. Based on the 1990 New Yorker article of the same name by Ian Frazier, Coyote vs. Acme is a unique, tongue-in-cheek spin on the old Wile E. Coyote and Roadrunner cartoons. The cartoons usually see Wile E. Coyote attempting to use a product from the Acme Corporation to kill the Roadrunner, and the defining running gag of the series sees every single Acme product backfiring on Wile E. Coyote in a very painful way. In Coyote vs. Acme, he’s finally had enough and decides to sue the company.

There’s some impressive talent behind Coyote vs. Acme. Guardians of the Galaxy director James Gunn produced Coyote vs. Acme from a story he co-wrote with Jeremy Slater and Samy Burch, while Dave Green, the filmmaker behind Earth to Echo and Teenage Mutant Ninja Turtles: Out of the Shadows, directed. The producers have assembled an impressive cast including a former Saturday Night Live cast member and a wrestler-turned-DC star. The Coyote vs. Acme cast features both returning voice actors and exciting new additions to the Looney Tunes universe.

Will Forte As Wile E. Coyote's Attorney

Will Forte with a beard in The Last Man on Earth

Will Forte leads the Coyote vs. Acme cast as Wile E. Coyote’s down-on-his-luck attorney. Forte is best known for his tenure as a Saturday Night Live cast member from 2002 to 2010. His most popular SNL character MacGruber even ended up getting his own feature film and streaming series spin-offs. Forte created and starred as Phil Miller in the post-apocalyptic sitcom The Last Man on Earth, for which he received two Emmy nominations for acting and one for writing. Forte’s other film roles include Doug Antsler in Booksmart and National Lampoon co-founder Doug Kenney in A Futile and Stupid Gesture.

John Cena As Acme Corporation's CEO

John Cena smiling in Blockers

John Cena plays the CEO of the Acme Corporation, who turns out to be Wile E.’s attorney’s old boss from his previous law firm. Cena first rose to prominence as a wrestler in the WWE. His most iconic acting roles are Peacemaker in the DC Extended Universe and Jakob Toretto in the Fast & Furious franchise. Cena has also played Mitchell Mannes in Blockers, Agent Jack Burns in Bumblebee, the voice of Ferdinand the Bull in Ferdinand, Roger in the Daddy’s Home movies, and Rocksteady in Teenage Mutant Ninja Turtles: Mutant Mayhem.

Lana Condor (Undisclosed Role)

Lana Condor on a bus in To All the Boys I've Loved Before

Lana Condor has an undisclosed role in the Coyote vs. Acme cast. Condor first rose to fame as a YouTuber before making her acting debut with the role of powerful atomic mutant Jubilee in the superhero blockbuster X-Men: Apocalypse. Her most renowned film work is her lead role as Lara Jean Covey in the To All the Boys series of romantic comedies. Condor has also played Saya Kuroki in the action comedy TV series Deadly Class, Koyomi in the sci-fi thriller Alita: Battle Angel, and the voice of the title character in the animated film Ruby Gillman, Teenage Kraken.

P.J. Byrne As Bill

Adam at his desk in The Boys

The role of Bill is played by P.J. Byrne in the Coyote vs. Acme cast. Byrne is best known for playing Adam Bourke in Amazon’s superhero satire The Boys, Nicky “Rugrat” Koskoff in Martin Scorsese’s crime epic The Wolf of Wall Street, and Bolin in Nickelodeon’s Avatar: The Last Airbender spin-off series The Legend of Korra. He has also played Mr. Alteli in the Will Ferrell holiday musical Spirited, Nelson in the Dwayne Johnson sci-fi actioner Rampage, Isaac Palmer in the supernatural slasher Final Destination 5, and Kenny Sommerfield in the dark comedy Horrible Bosses.

Nancy Linehan Charles As Cherry

Peg smiling in Young Sheldon

Nancy Linehan Charles appears in the Coyote vs. Acme cast in the role of Cherry. Charles is best known for her recurring roles as Connie in Six Feet Under and Pastor Jeff Difford’s secretary Peg in Young Sheldon. Charles’ previous movie roles include Mrs. Cutter in the 2009 remake of The Stepfather, Mrs. Long in Mike Nichols’ political dramedy Charlie Wilson’s War, and Precrime Director Lamar Burgess’ wife Celeste in Steven Spielberg’s sci-fi noir Minority Report. She also played Judith in Light as a Feather, Dr. Bowman in 3 from Hell, and Anne in The Way Back.

Will Any Looney Tunes Characters Appear?

Bugs Bunny eating a carrot

Jeff Bergman as Bugs Bunny: Jeff Bergman reprises his role as the voice of Bugs Bunny in Coyote vs. Acme. Bergman was the first voice actor to replace Mel Blanc in the role of Bugs Bunny and several other Warner Bros. cartoon characters after Blanc passed away in 1989. He also voiced Droopy in the Tom & Jerry movie and the Joker in the direct-to-video superhero films Batman: Return of the Caped Crusaders and Batman vs. Two-Face.

Tucker Hawkey as Roadrunner: Tucker Hawkey provides the voice of the Roadrunner in the Coyote vs. Acme cast. As it stands, the role of the Roadrunner in Coyote vs. Acme is Hawkey’s only acting credit on IMDb. Hawkey is best known as an impressionist who has posted his best impressions on YouTube and TikTok.