Catch up with Dr. Now's patients to see how their journeys are progressing.

Trapped in a child's body, 22-year-old Shauna Rae fights for independence.

Best friends battle morbid obesity with heart and a wicked sense of humor.

Follow the ups and downs of marriage after the 90 days.

World-renowned surgeons help people with rare or life-threatening tumors.

For these women, life can be a tall challenge when you're over 6 feet tall.

With the support of her family, Jazz faces life as a transgender female.

The Slaton sisters are back and it’s the heaviest season yet.

People who've lost massive amounts of weight undergo skin removal surgery.

Three morbidly obese cousins struggle to lose weight.

Members of the Amish and Mennonite communities face "new world" freedoms.

These very unique families decide it's time to bring in a sister wife.

Couples try to turn a flirty fling in paradise into a permanent passion.

Chris Jacobs and Lisa Joyner help people reunite with loved ones.

If they can't throw out anything, they stand to lose everything.

Morbidly obese individuals work to change their lives forever.

The world's largest family of little people makes a very big impression.

People recount their true stories about living with evil family members.

A man and woman battle extreme environments without food, water or clothes.

Hoarders profiles adults who suffer from extreme hoarding.