- Chris Hemsworth
- Agent H
- Tessa Thompson
- Agent M
- Kumail Nanjiani
- Pawny
- Rebecca Ferguson
- Riza
- Rafe Spall
- Agent C
- Emma Thompson
- Agent O
- Liam Neeson
- Agent High T
- Laurent Bourgeois
- Alien Twin
- Larry Bourgeois
- Alien Twin
- Kayvan Novak
- Vungus/Nasr/Bassam
- Spencer Wilding
- Luca Brasi
- Marcy Harriell
- Molly's Mom
- Inny Clemons
- Molly's Dad
- Aaron Serotsky
- Men in Black No. 1
- Mandeiya Flory
- Young Molly
- Matthew Bates
- FBI HR Guy
- Sartaj Garewal
- CIA Recruiter
- Stephen Wight
- Guy
- Brian Silliman
- Cabbie
- John Sousa
- Jimmy the Alien
- Jeff Kim
- Lead MIB Agent
- Michael Adams
- MIB Lead Interrogator
- Mike Capozzola
- Veteran MIB Agent
- Annie Burkin
- Nerlene
- Andrew Greenough
- Freddie the Alien
- F. Gary Gray
- Director
- Art Marcum
- Screenwriter
- Matt Holloway
- Screenwriter
- Walter F. Parkes
- Producer
- Laurie MacDonald
- Producer
- Steven Spielberg
- Executive Producer
- Edward Cheng
- Executive Producer
- Howard Chen
- Executive Producer
- E. Bennett Walsh
- Executive Producer
- Riyoko Tanaka
- Executive Producer
- David Beaubaire
- Executive Producer
- Barry Sonnenfeld
- Executive Producer
- Stuart Dryburgh
- Cinematographer
- Christian Wagner
- Film Editing
- Zene Baker
- Film Editing
- Matt Willard
- Film Editing
- Danny Elfman
- Original Music
- Chris Bacon
- Original Music
- Charles Wood
- Production Design
- Thomas Brown
- Supervising Art Direction
- Julian Ashby
- Art Director
- David Doran
- Art Director
- Chris "Flimsy" Howes
- Art Director
- Mark Swain
- Art Director
- Su Whitaker
- Art Director
- Steve Wong
- Art Director
- John Bush
- Set Decoration
- Penny Rose
- Costume Design
- David Rubin
- Casting
- Reg Poerscout-Edgerton
- Casting
