- Hep A vs. B vs. C
- Coinfection
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Because there is no vaccination available against hepatitis C, hepatitis C is often considered the worst hepatitis.
Hepatitis A is not a chronic infection, whereas hepatitis B and C can and do cause chronic infections. There are vaccines to prevent hepatitis A and B but none for hepatitis C, which makes it more lethal than hepatitis A and B.
According to studies, up to 70% of people who are infected with hepatitis C develop chronic liver disease, and up to 20% of people develop cirrhosis. According to the CDC, up to 5% of people with hepatitis C may die from cirrhosis or liver cancer. The risk of chronic infections is high if infections occur at a young age.
Viral hepatitis is the leading cause of hepatitis in the United States, with the most common culprits being hepatitis B and C viruses, which are transmitted through blood and body fluids. Hepatitis B and C viruses do not always cause symptoms, but if left untreated, they can have serious long-term consequences.
Hepatitis A, B, and C: what’s the difference?
Hepatitis (inflammation of the liver) is often caused by a virus that comes in different strains. The most common strains of hepatitis are hepatitis A, B, and C. They all are contagious, but they differ primarily by the way they are spread.
Table: Differences among hepatitis A, B, and C
Factors | Hepatitis A | Hepatitis B | Hepatitis C |
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Symptoms |
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Causes |
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Incubation period | 15-50 days (average 28 days) | 45-160 days (average 90 days) | 14-180 days (average 45 days) |
Risk population |
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Vaccinations |
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No vaccination available; however, research is positive in this aspect |
Treatment |
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Treatment is available | Treatment is available |
Post diagnosis |
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Severity | Rarely severe |
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SLIDESHOW
See SlideshowIs there a possibility of coinfection?
Both hepatitis B and C can be present at the same time. Hepatitis C may become more dominant, reducing hepatitis B levels in the bloodstream to low or undetectable levels.
Prior to starting hepatitis C treatment, people should have their blood tested for hepatitis B using the three-part blood test (HBsAg, anti-HBc total, and anti-HBs). According to the American Association for the Study of Liver Diseases treatment guidelines, people who are currently infected with hepatitis B (HBsAg positive) or who have recovered from a previous infection (HBsAg negative and anti-HBc positive) should be managed carefully to avoid dangerous elevations in liver enzymes that can lead to liver failure.
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What are the Difference between Hepatitis A, B and C? https://healthtalk.unchealthcare.org/whats-the-difference-between-hepatitis-a-b-and-c/
The ABCs of Hepatitis – for Health Professionals: https://www.cdc.gov/hepatitis/resources/professionals/pdfs/abctable.pdf
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Learn about how the hepatitis B surface antibody test works, and how its results indicate whether you are immune to the virus or not.Should I Take PrEP for HIV?
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What Does it Mean If You Have Urobilinogen in Your Urine?
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Ombitasvir is a direct-acting antiviral drug that is used to treat hepatitis C. The medication acts as a hepatitis C virus inhibitor and is a dipeptide derivative. It is mostly used as a combination drug containing dasabuvir sodium dihydrate, paritaprevir, and ritonavir under the trade name Viekira Pak, which is FDA-approved. Ombitasvir works by inhibiting the NS5A protein, which helps in the replication of the hepatitis C virus.