Famous actors from South Carolina

- Born: Charleston, South Carolina (6/14/1954)
- Known for:
--- Scott Pritchard in "No Way Out" (1987)
--- General Bethlehem in "The Postman" (1997)
--- Chick in "Armageddon" (1998)

- Born: Charleston, South Carolina (11/1/1976)
- Known for:
--- Will in "The Invitation" (2015)
--- Mechanic in "Devil" (2010)
--- Grey Trace in "Upgrade" (2018)

- Born: Anderson, South Carolina (11/29/1976)
- Died: 8/28/2020
- Known for:
--- T'Challa in "Black Panther" (2018)
--- T'Challa in "Captain America: Civil War" (2016)
--- T'Challa in "Avengers: Infinity War" (2018)

- Born: Columbia, South Carolina (6/4/1969)
- Known for:
--- Mark Mitchell in "The Descendants" (2011)
--- Tevin Downey in "I Love You, Man" (2009)
--- Jeremy in "Seeking a Friend for the End of the World" (2012)

- Born: Andrews, South Carolina (2/7/1965)
- Known for:
--- Andre Allen in "Top Five" (2014)
--- Caretaker in "The Longest Yard" (2005)
--- Producer in "Head of State" (2003)

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- Born: Orangeburg, South Carolina (6/17/1983)
- Known for:
--- Hassan in "The Hundred-Foot Journey" (2014)
--- Jeet Kumar in "Viceroy's House" (2017)
--- Ryan Ray in "Halt and Catch Fire" (2016)

- Born: Charleston, South Carolina (7/3/1962)
- Known for:
--- Greg Montgomery in "Dharma & Greg" (1997-2002)
--- Aaron Hotchner in "Criminal Minds" (2005-2020)
--- Stephen Chase in "Far and Away" (1992)

- Born: Charleston, South Carolina (12/18/1944)
- Known for:
--- Fitz in "Halloween H20: 20 Years Later" (1998)
--- Moss Woodley in "The Blob" (1988)
--- Jet Black in "Cowboy Bebop: The Movie" (2001)

- Born: Columbia, South Carolina (8/26/1976)
- Known for:
--- Luke Cage in "Luke Cage" (2016-2018)
--- Colonel in "Men in Black 3" (2012)
--- David in "Extinction" (2018)

- Born: Charleston, South Carolina (10/31/1975)
- Known for:
--- Vernon in "Limitless" (2011)
--- Darden in "3:10 to Yuma" (2007)
--- Donny Ray Black in "The Rainmaker" (1997)

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- Born: Aiken, South Carolina (2/8/1972)
- Known for:
--- Huge Santa in "Jingle All the Way" (1996)
--- Captain Insano in "The Waterboy" (1998)
--- Big Show in "Fighting with My Family" (2019)

- Born: Sumter, South Carolina (12/27/1981)
- Known for:
--- Lawrence Walker in "Insecure" (2016-2021)
--- Payback in "Top Gun: Maverick" (2022)
--- Franklin Thomas in "Mrs. America" (2020)

- Born: Columbia, South Carolina (2/23/1983)
- Known for:
--- Tom Haverford in "Parks and Recreation" (2009-2015)
--- Dev in "Master of None" (2015-2021)
--- Mub in "Epic" (2013)

- Born: Rock Hill, South Carolina (10/30/1949)
- Known for:
--- Wade in "Eight Legged Freaks" (2002)
--- General W.O. West in "Stargate" (1994)
--- Tom Nuttall in "Deadwood" (2004-2006)

- Born: Columbia, South Carolina (2/1/1984)
- Died: 8/19/2013
- Known for:
--- Chris Comer in "Friday Night Lights" (2004)
--- Jett Jackson in "The Famous Jett Jackson" (1998-2001)
--- Delmar in "The Hills Have Eyes 2" (2007)

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- Born: Charleston, South Carolina (12/21/1965)
- Known for:
--- Motel Clerk in "Road Trip" (2000)
--- Rock in "Reality Bites" (1994)
--- Lon in "Employee of the Month" (2006)

- Born: Cheraw, South Carolina (6/12/1953)
- Known for:
--- Earl Unger in "Home Alone 3" (1997)
--- Jimmy Palumbo in "John Q" (2002)
--- Robert in "Here and There" (2009)

- Born: Myrtle Beach, South Carolina (7/22/1942)
- Died: 5/26/2020
- Known for:
--- Skinny Dubois in "Unforgiven" (1992)
--- Hector Savage in "The Naked Gun 2½: The Smell of Fear" (1991)
--- Ralph in "In the Heat of the Night" (1967)

- Born: Greenville, South Carolina (2/2/1942)
- Known for:
--- Joe in "American Graffiti" (1973)
--- Tex in "Midnight Express" (1978)
--- Crazy Lee in "The Wild Bunch" (1969)

- Born: Charleston, South Carolina (6/16/1988)
- Known for:
--- David Raskin in "Project Almanac" (2015)
--- Edgar in "Allegiant" (2016)
--- Edgar in "The Divergent Series: Insurgent" (2015)

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- Born: Camden, South Carolina (11/20/1946)
- Died: 5/24/2021
- Known for:
--- Sebastian in "The Little Mermaid" (1989)
--- Kron in "Dinosaur" (2000)
--- Dizzy in "Bird" (1988)

- Born: Pelion, South Carolina (1/1/1938)
- Died: 6/28/2019
- Known for:
--- English in "Escape from Alcatraz" (1979)
--- Henry Styles in "The Station Agent" (2003)
--- ML in "Do the Right Thing" (1989)

- Born: Clinton, South Carolina (5/24/1969)
- Known for:
--- Cole Brown in "Martin" (1992-1997)
--- Pitterson's Father in "The Messenger" (2009)
--- Stats Jefferson in "Ed" (1996)

- Born: Charleston, South Carolina (5/12/1990)
- Known for:
--- Additional Voices in "Final Fantasy VII Remake" (2020)
--- Herman Schultz in "Marvel Adventures: Spider-Man and the Monsters of Manhattan" (2021)
--- Obi-Wan Kenobi in "Kenobi: A Star Wars Story" (2019)

- Born: Columbia, South Carolina (6/24/1998)
- Known for:
--- Flint in "Agents of S.H.I.E.L.D." (2017-2020)
--- Protagonist in "Logic: 1-800-273-8255 Ft. Alessia Cara, Khalid" (2017)
--- Troy Dixon in "Bella and the Bulldogs" (2015-2016)

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- Born: Columbia, South Carolina (12/25/1902)
- Died: 1/1/1969
- Known for:
--- Lt. of Detectives Dundy in "The Maltese Falcon" (1941)
--- Al Kruger in "Bullets or Ballots" (1936)
--- Steve MacBride in "The Adventurous Blonde" (1937)

- Born: Barnwell, South Carolina (5/3/1933)
- Died: 12/25/2006
- Known for:
--- Reverend Cleophus James in "The Blues Brothers" (1980)
--- Self in "Mr. Dynamite: The Rise of James Brown" (2014)
--- Soundtrack in "Django Unchained" (2012)

- Born: Greenwood, South Carolina (8/18/1948)
- Known for:
--- Earl Burke in "Dr. Death" (2021)
--- Mr. Arthur (segment "The Gal Who Got Rattled") in "The Ballad of Buster Scruggs" (2018)
--- Captain August Robertson in "The Knick" (2014-2015)

- Born: Anderson, South Carolina (2/3/1993)
- Known for:
--- Julian in "Search Party" (2016-2021)
--- Miles Finer in "God Friended Me" (2018-2020)
--- Courtney Rose in "The Mayor" (2017-2018)

- Born: Charleston, South Carolina (1/16/1971)
- Known for:
--- Richard in "The Bucket List" (2007)
--- Self - Guest in "Whose Line Is It Anyway?" (2013-2021)
--- Agent Daniel T. Keating in "NCIS" (2008)

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- Born: Florence, South Carolina (8/31/1962)
- Known for:
--- Producer in "Buried History with Mark Walberg" (2015)
--- Mark Walberg in "Son of the Beach" (2002)
--- Stan in "I Want to Marry Ryan Banks" (2004)

- Born: South Carolina (8/21/1938)
- Known for:
--- Toothless Man in "Deliverance" (1972)
--- Harmon Teaster in "Ghost Town: The Movie" (2007)
--- Cowboy in "Hillbilly Blood" (2013)

- Born: Sumter, South Carolina (2/5/1951)
- Died: 2/18/2019
- Known for:
--- Morten Entrekin in "Deep Impact" (1998)
--- Texas Man in "Nixon" (1995)
--- Jim Soams in "Big Eden" (2000)

- Born: Mauldin, South Carolina (5/19/1976)
- Known for:
--- Kevin Garnett in "Uncut Gems" (2019)
--- Producer in "Broken Rim"
--- Wilt 'The Stilt' Chamberlain in "Rebound: The Legend of Earl 'The Goat' Manigault" (1996)

- Born: Myrtle Beach, South Carolina (2/4/1982)
- Known for:
--- Wade in "You Got Served" (2004)
--- Bishop in "Big Momma's House 2" (2006)
--- Boy with Cross in "Forrest Gump" (1994)

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- Born: Summerville, South Carolina (1/13/1976)
- Known for:
--- Jim in "Boyhood" (2014)
--- Sgt. Aaron Barnes in "NCIS" (2004)
--- Ryan Steele in "V.R. Troopers" (1994-1995)

- Born: Hampton, South Carolina (2/7/1962)
- Known for:
--- News Cameraman in "War of the Worlds" (2005)
--- Mike in "V.I.P." (1999)
--- Coach Jeriba Sinclair in "The Hard Times of RJ Berger" (2010-2011)

- Born: Lexington, South Carolina (7/20/1909)
- Died: 1/28/1993
- Known for:
--- Fred in "The Hills Have Eyes" (1977)
--- Shakey Malone in "Vigilante Force" (1976)
--- Pop in "The Longest Yard" (1974)

- Born: Columbia, South Carolina (6/15/1905)
- Known for:
--- Zeke in "ER" (2008)
--- Henry Cole in "Southland" (2009)
--- Marquez in "The Night Shift" (2016)

- Born: Spartanburg, South Carolina (7/19/1982)
- Known for:
--- Airforce Airman Taylor in "Super 8" (2011)
--- Hugo in "Complete Strangers" (2020)
--- John Kellogg in "The Food That Built America" (2019-2021)

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- Born: South Carolina (1/16/1922)
- Died: 4/22/1981
- Known for:
--- Harrison in "The Fugitive" (1966)
--- Rudolph Slocum in "Anna Lucasta" (1958)
--- Jr. OOD in "The Twilight Zone" (1960-1963)