- Denzel Washington
- Frank Lucas
- Russell Crowe
- Richie Roberts
- Chiwetel Ejiofor
- Huey Lucas
- Cuba Gooding Jr.
- Nicky Barnes
- Josh Brolin
- Detective Trupo
- Ted Levine
- Lou Toback
- Armand Assante
- Dominic Cattano
- RZA
- Moses Jones
- John Ortiz
- Javier J. Rivera
- John Hawkes
- Freddie Spearman
- Roger Guenveur Smith
- Nate
- Ruby Dee
- Mama Lucas
- Idris Elba
- Tango
- Carla Gugino
- Laurie Roberts
- Yul Vazquez
- Alfonse Abruzzo
- Ruben Santiago-Hudson
- Doc
- Joe Morton
- Charlie Williams
- Ridley Scott
- Director, Producer
- Steven Zaillian
- Executive Producer, Screenwriter
- Brian Grazer
- Producer
- Dan Griffin
- Producer
- Nicholas Pileggi
- Executive Producer
- Branko Lustig
- Executive Producer
- James Whitaker
- Executive Producer
- Michael Costigan
- Executive Producer
- Harris Savides
- Cinematographer
- Pietro Scalia
- Film Editing
- Marc Streitenfeld
- Original Music
- Arthur Max
- Production Design
- Nicholas Lundy
- Art Director
- Beth A. Rubino
- Set Decoration
- Leslie E. Rollins
- Set Decoration
- Janty Yates
- Costume Design
- Avy Kaufman
- Casting
