I am starting to take Pure Encapsulations Strontium Citrate supplement as well as a combined Vitamin D3/ Vitamin K2 tablet, and Red Mineral Algae ( calcium). However, I have read that K2 is a blood clotting agent and Strontium Citrate can cause blood clots. Is there anyone who can give me more information about this? Especially those who take both K2 and SC? I do not want to take medication although my spine DEXA numbers are really high.
Thank you. My spine is -4.4. After a hyperparathyroidectomy, it went from -4.9 to -4.4, but it is still a terrible score. I will start with 45 mcg of mk7. SC is strontium citrate.
The information that you are referencing about strontium and clots is information tied to strontium via ranelate. Strontium via citrate has never been tied to clots in any of the strontium via citrate studies.
Plus, the clots info was from a population study with no controls. A study result that has never been able to be reproduced even though Denmark spent years trying to do so.
I can give you the hotlinks to all the above info if you need it.
Pure Encapsulations Strontium Citrate supplement is 227 mg for one capsule. What are your t scores? I ask because this dose is not recommended for osteoporosis or even osteopenia according to the research. It is closer to the osteopenia research though. So are you taking it for osteopenia?
No, I am taking it for osteoporosis ( spine -4.4) Apparently, I should be taking 680mg daily, but I am starting off slowly to see if there are any side effects. I plan on building up to 3 capsules at night before bed.
Thank you for this helpful information. I would love the links, so I can read more.
So...perhaps strontium citrate does not work and could do more harm than good? Many on this and the Algaecal forum have been pleased with their DEXA results while using it . I know DEXA gives a false reading if one is taking SC, but many on this site also have not fractured. I am trying to find a way not to take one of the osteoporosis drugs, all of which also have side effects.
Here are some links. I have many more which I can provide upon specific request.
Only one population study has linked strontium via ranelate to cardio vascular events; no studies have linked strontium citrate to cardio vascular events.
Links:
Strontium via ranelate studies about cardio vascular events:
"Three observational analyses carried out by separate groups in the setting of two different healthcare systems did not report a signal for increased cardiac risk with strontium ranelate treatment [12-14]. Why three observational studies failed to replicate the findings from a pooled analysis of data from RCTs remains a question for the research agenda. The observational studies had different designs and collected data from different types of sources but still came to the same conclusion. They were all highly robust, with sufficient statistical power.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196504/
The clot rate "rate is similar to estimates in populations of similar age and corresponds to the incidence found in patients from phase III clinical studies and observational cohort studies of strontium ranelate on this topic. "
https://pubmed.ncbi.nlm.nih.gov/20553059/
"Conclusions
Analysis in the CPRD did not find evidence for a higher risk for cardiac events associated with the use of strontium ranelate in postmenopausal osteoporosis."
https://link.springer.com/article/10.1007/s00198-013-2582-4
Some Strontium Citrate studies:
Mots and Comb
https://strontiumforbones.blogspot.com/2017/02/mots-and-comb-study-comparison.html
Mots one year double blind:
"did not produce adverse effects psychologically or physically in our cohort and there was a high compliance rate (92.4%)."
https://core.ac.uk/download/pdf/234048393.pdf
Comb:
"There were no reported side effects with the use of this therapy among those taking the intervention for the year and the literature suggests long-term safety with each of these agents—this might contribute to greater compliance with the subgroup of patients who are reluctant to use pharmacologic therapies."
Michalek study, 6 months no adverse effects seen:
No, a dxa of a strontium is not useless. If this was correct then in Europe where strontium ranelate is used the DXA would not be recommended for strontium users, but the royal osteoporosis society does recommend dxa for strontium users.
The first DXA after beginning strontium will need to be adjusted about 10%. REms makes this problem moot as does the soft ware read of DEXA by TBS. THis is an old argument which is becoming moot.
No drug conflicts with calcium or with strontium; they are earth minerals found naturally in most of the worlds ground water.
Yes, ck it for decreasing.
Research on mice shows a decrease in blood pressure with mice supplemented with strontium. Obviously, this needs to be further investigated with human studies.
2023 research Conclusion: "Strontium can reduce the blood pressure of hypertensive mice by regulating the eNOS/NO pathway and reducing the production of inflammatory factors."
Well, Servier obviously thinks it works since that big Pharma company spent millions to research it and bring it to market tied to ranelate so they could patent it.
There is research that goes back to the 1950's by the armed services that strontium has a positive effect on bones, teeth.
Surgeons are implanting strontium infused bone implants into the skull, jaws, knees, ankles because they know that it works.
Sensodyne has strontium in it because it works.
ETC ETC.
Obviously, strontium works.
REMS or have your dexa interpreted by TBS to ck your bone quality.
Kathleen, thank you for providing this excellent information. I now feel more confident taking strontium citrate, but will start off slowly and then build up to 680mg. I also read in previous articles that you mentioned biodentical hormones, but I am 73 and probably too old at this point. Do you also take Vitamin K? This seems to be another popular supplement to complement Vitamin D3 and Calcium.
Just a side note, I would suggest that you always ask whoever, on Inspire etc., is giving you information whether pro or con to tell you what drug/ supplement/ plan they are taking/following and what the change in their numbers have been in their dexa, etc. Some people just want to shoot down, especially strontium, but are seldom forth coming with their own choices and situation. A friend of mine calls it strontium derangement syndrome, ha.
My numbers as I have told you have gone from osteoporosis -2.8 to Normal bone readings -.7. no side effects, no fractures. You will not find me posting anti information on other people's chosen drug plan. I will post research and personal information about my own drug plan.
There are better drug choices available today with much better results and fewer side effects. Michael Lavacote has some great videos that have a good overview of pharma meds. I do not regret my strontium choice; my results have been too good. But I totally understand why many people feel that some newer pharma drugs, especially, are good choices for them.
Age is not considered a problem now with the new hormone therapy, bioidentical and topical. The Cochrane study that I shared earlier tested this and found safety for older women even after 10 years into menopause. I do think that we need more studies.
What is considered for all users is heart health and the correct checks of hormones before and during use. So a good dr is needed that is up on how to ck hormones, systemic and vaginally. Your local compounder should be able to give you a list of drs that use compounded topical hormones, especially good to look for is a hormone dr that uses vaginaly progesterone when needed.
I do think that a salivia test cking your hormones and interpreted by a hormone expert would be useful for you to see exactly what your situation is presently. You may not need estradiol systemically; l do not. You may only use hormones vaginally, many breast cancer survivors do this.
I think that all women should have their hormones cked, preferably by salivia to make sure that you have a safe level. Some women produce estradiol abundantly in menopause and need progesterone for safety to counter the estradiol. This is a fact that is ignored by many drs, and they will just give women estrogen without cking their current levels then hormones are blamed when problems result. The real problem are drs that are not educated on hormone use for women in menopause.
I did take vit k; my husband continues to take it for heart health. I seemed to have had a reaction to the therapeutic level of vit k which I was taking, so I stopped the vit k. I support totally taking vit k for especially heart health and making sure that your calcium goes to your bones and not to clog up your circulatory system. I am considerning trying vit k again at a lower level.
Here are some posts on general strontium information:
https://www.inspire.com/groups/bone-health-and-osteoporosis/discussion/hrt-hormones-and-blood-clots/
https://www.inspire.com/groups/bone-health-and-osteoporosis/discussion/tbs-dexa-and-strontium/
Hormone posts:
https://www.inspire.com/groups/bone-health-and-osteoporosis/discussion/hormones-bones-bladder-brain/
Does Strontium go by another name? From the Sensodyne website, all their toothpastes seem to have the exact same ingredients:
Active Ingredient
Stannous fluoride
Inactive Ingredients
Glycerin, PEG-8, hydrated silica, pentasodium triphosphate, flavor, sodium lauryl sulfate, titanium dioxide, polyacrylic acid, cocamidopropyl betaine, sodium saccharin
There are several varities of sensodyne now. Not sure where you are on the sensodyne webpage, or why you are not seeing the rather long list of sensodyne products including the original, containing strontium, on the web page.
The first, original, containing strontium, is still available and is on the sensodyne website. Below is the link to the rather large page of all the different sensodyne toothpaste, all with different ingredients. Below also is the product detail listing for sensodyne original.
Product Details
Active ingredients
Strontium Chloride Hexahydrate 10%w/w
Sensodyne original at the bottom
https://www.sensodyne-me.com/en_AE/products.html
Also, here is a link to the time line for the different sensodyne products and when they were developed:
Interesting story, on Inspire one of the users was an adamant anti strontium poster.
She had had some bad results from a bisphosphonate with resulting jaw necrosis. She was having to have some dental work and was overjoyed that her dentist had found a product to use that would work on her and allow her bone to grow and be healthy. When she described it, I replied and told her that I thought that she was going to be using a strontium laced implant and/or injections. She never replied and deleted all the posts that she had written about the "great" new break thru for her condition that would grow bone. My private messages to her went unanswered. I trust and hope that her strontium laced bone is now healthy, and that she is doing well.
It may be a geographical thing. I was on the US version of the site: https://www.sensodyne.com/en-us/contact/
One link you supplied is Central America (although in English) and the other I believe is the UAE (again although in English)
It's possible different ingredients are used in different countries.
I was just curious if there was another name in case that was the issue. But it seems it's just what's available in each country.
Looks like it is called sensodyne original.
This page just says sensodyne.com the link to the original links to the amazon page that sells it. But yes the money does not seem like it is not usa.
https://www.sensodyne-me.com/en_AE/products.html
So maybe the original is now only available outside the usa.
Maybe because strontium is a supplement in the usa and therefore is monitoried in a particular way. Not sure; I will try to email sensodyne. But the fact still remains that sensodyne via original has strontium in it.
