Charlotte Sofie von Sachsen-Coburg-Saalfeld was born 24 September 1731 in Coburg, Bavaria, Germany to Franz Josias von Sachsen-Coburg-Saalfeld (1697-1764) and Anna Sophia von Schwarzburg-Rudolstadt (1700-1780) and died 2 August 1810 Schwerin, Mecklenburg-Vorpommern, Germany of unspecified causes. She married Ludwig von Mecklenburg-Schwerin (1725-1778) 13 May 1755 in Schwerin, Mecklenburg-Vorpommern, Germany.
Children
| Name | Birth | Death | Joined with |
| Friedrich Franz I. von Mecklenburg-Schwerin (1756-1837) | 10 December 1756 Schwerin, Germany | 1 February 1837 Ludwigslust, Germany | Luise von Sachsen-Gotha-Altenburg (1756-1808) |
| Sophie Friederike von Mecklenburg-Schwerin (1758-1794) | 24 August 1758 | 29 November 1794 | Frederik of Denmark (1753-1805) |
Footnotes (including sources)
| ‡ General |
