- Ricki Lake
- Tracy Turnblad
- Divine
- Edna Turnblad / Arvin Hodgepile
- Jerry Stiller
- Wilbur Turnblad
- Sonny Bono
- Franklin von Tussle
- Vitamin C
- Amber von Tussle
- Ruth Brown
- Motormouth Mabel
- Michael St. Gerard
- Link Larkin
- Deborah Harry
- Velma Von Tussle
- Leslie Ann Powers
- Penny Pingleton
- Clayton Prince
- Seaweed
- Mink Stole
- Tammy
- Shawn Thompson
- Corny Collins
- Ric Ocasek
- Beatnik Cat
- Pia Zadora
- Beatnik Chick
- John Waters
- Co-Producer, Director
- Stanley F. Buchthal
- Co-Producer
- Pat Moran
- Associate Producer, Casting
- Rachel Talalay
- Producer
- David Insley
- Cinematographer
- Janice Hampton
- Film Editing
- Mary Colquhoun
- Casting
- Vincent Peranio
- Art Director, Production Design
- Van Smith
- Costume Design
- Julia Cort
- Second Assistant Director
