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Bonny Jean Jacobs, 78, the mother-in-law of Sen. Joe Biden, the Democratic vice presidential nominee, died Sunday after a long illness, a spokesman for Biden said.

Biden, of Delaware, canceled all campaign appearances Monday and Tuesday to be with his wife, Jill Jacobs Biden, and their families.

Mrs. Jacobs had been in hospice care in the Philadelphia suburbs, not far from the Bidens’ home in Wilmington, Del.

She was the widow of Donald C. Jacobs, a savings and loan executive from Willow Grove, Pa., who died in 1999. Mrs. Jacobs stayed home to raise Jill and her four younger sisters. The couple were married for 50 years.

Biden’s spokesman, David Wade, said a memorial service would be held Tuesday in Abington, Pa.