Elizabeth Anne Velásquez (/ˈlɪzi vəˈlæskɛz/; born March 13, 1989) is an American motivational speaker, activist, author, and YouTuber. She was born with an extremely rare congenital disease called Marfanoid–progeroid–lipodystrophy syndrome that, among other symptoms, prevents her from accumulating body fat and gaining weight. She is blind in her right eye, which began to cloud over when she was four, and she is vision-impaired in her left eye. Her conditions resulted in bullying during her childhood. During her teenage years, she faced cyberbullying, and was dubbed the "World's Ugliest Woman" in a video posted on YouTube in 2006 when she was 17, which ultimately inspired her to take up motivational speaking.