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Recommended International Non-proprietary Name (rINN) Of Drugs (Full List) With Former Name

RINN and Formal List
rINN and Former List
One of the functions of World Health Organisation (W.H.O) is the regulation of International Non-proprietary Names (I.N.Ns) which was established in 1950.
Until date, about 7,000 names have been published. However, all of the pharmaceutical products available today are in their trade names, which are used for prescribing, dispensing, promotion or buying. The manufacturer of those product selects the names they want to use. 

It should be known that two different manufacturers could produce one product and give it different trade names that they like. However, both products will have the same generic name (Non-Proprietary Name) maybe with different strength.

National and international commissions design generic names. The naming has made it easy for medical practitioners to know the function, pharmacology and therapeutic effects of any drug once the INN is known.


Read Also: The Full List Of Drug Classification Of Nigeria Essential Medicine List


The name is developed following the guidelines of international bodies including the International Union of Pure and Applied Chemistry (I.U.P.A.C) nomenclature. This was applied when it was observed that most of the names were quite long and difficult to pronounce. This led to the adoption of a new set of names to eliminate those observed problems known as rINN (Recommended International Non-proprietary Name). Take acetaminophen as an example that has a second name as paracetamol. There is need to accept one to avoid future misrepresentation.


It should be noted that these naming affected mostly old drugs with old names as new products are given a standard name from the start.

To get a new product registered in the rINN, a request for a rINN is submitted either to the National Nomenclature Commission (N.N.C) of individual country or to WHO. The details of the new product are detailed out in an application like the pharmacological action and the name of the manufacturer. The proposed name of the manufacturer is examined and if approved selected. All regulatory bodies involved must agree at one name before it becomes official. The manufacturer can send two names.

There may be ground for disapproval from anybody who lays complain to the organisation objecting to the proposed name. Such objections are only be attended to within four months after the name was proposed, if not it will not be entertained.

Approval Of New Product Name

To be approved, an rINN must:

  1. be distinctive in sound and spelling
  2. not too long
  3. not liable to confusion with other names known
All approved new drugs are published in the journal of WHO. Drug Management and Policy unit of WHO is saddled with the responsibility of publishing new drug information.
rINN are intended to be used in:

  1. pharmacopoeia
  2. labelling
  3. advert
  4. scientific literature
  5. product names especially for generic compounds

Nigeria And rINN

The use of rINN in Nigeria is similar to other countries like Britain and Australia which is a requirement for exporting products out of the country. This may not count for local products within the country.

Since the adoption of rINN in Nigeria, the following drugs have been affected. The list here indicated the old names with the new adopted rINN. New drugs do not have old names hence are not included here.

Former Name (Old Name)
rINN
Adrenaline
Epinephrine
Amethocaine
Tetracaine
Amoxicilin
Amoxicillin
Amphetamin
Amphetamine
Amylobarbitone
Amobarbital
Amylobarbitone sodium
Amobarbital sodium
Beclomethasone
Beclometasone
Bendrofluazide
Bendroflumethizide
Benzhexol
Trihexyphenidyl
Benztropine         
Benzatropine
Busulphan
Busulfan
Butobarbitone
Butobarbital
Cephalexin 
Cefalexin
Cephradine
Cefradine
Chlorbutol
Chorobutanol
Chlormethiazole
Clomethiazole
Chlorpheniramine
Chlorphenamine
Chlorthalidone
Chlortalidone
Cholecalciferol
Colecalciferol
Cholestyramine
Colestyramine
Clomiphene
Clomifene
Corticotrophin
Corticotropin
Cyclosporine
Ciclosporin
Dimethicone (s)
Dimeticone
Dimethyl sulphoxide
Dimethyl sulfoxide
Doxycycline HCL (hemihydrate hemiethanolate)
Doxycycline Hyclate
Ethinyloestradiol
Ethinylestradiol
Flumethasone
Flumetasone
Flupenthixol
Flupentixol
Frusemide
Furosemide
Guaiphensin
Guaifenesin
Indomethacin
Indomethacin
Lignocaine
Lidocaine
Methylene blue
Methylthioninium chloride
Nicoumalone
Acenocoumarol
Noradrenaline
Epinephrine
Oestradiol
Estradiol
Oestriol
Estriol
Oestrone
Estrone
Phenobarbitone
Phenobarbital
Pramoxine              
Pramocaine
Procaine penicillin
Procaine benzylpenicillin
Riboflavine
Riboflavin
Salcatonin
Calcitonin (salmon)
Sodium calciumedetate
Sodium calcium edetate
Stilboestrol
Diethylstilbestrol
Sodium cromoglycate
Sodium cromoglicate
Sulphacetamide
Sulfacetamide
Sulphadiazine
Sulfadiazine
Sulphamethoxazole
Sulfamethoxazole
Sulphapyridine
Sulfapyridine
Sulphasalazine
Sulfasalazine
Sulphathiazole
Sulfathiazole
Thiabendazole
Tiabendazole
Sulphinpyrazone
Sulfinpyrazone
Thiopentone
Thiopental
Thyroxine sodium
Levothyroxine sodium
Urofollitrophin
Urofollitropin


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