The Best Horror Movies About Evil Experiments
- 1Jeff Goldblum, Geena Davis, John Getz
In a twisted tale of scientific ambition gone horribly awry, a brilliant scientist's quest for teleportation results in a nightmarish experiment that fuses his DNA with that of a common housefly. As the scientist begins his gruesome transformation into a grotesque human-fly hybrid, he must grapple with the ramifications of his newfound powers and the potential for irreversible disaster. With its truly gory visuals and chilling premise, this horror classic will leave you questioning the limits of scientific progress.
More The Fly
- #129 of 399 onThe Best Movies Of The 1980s, Ranked
- #3 of 64 onThe Best Horror Movie Remakes Of All Time
- #42 of 125 onThe 100+ Grossest Movies Ever
- 2Colin Clive, Mae Clarke, John Boles
In this iconic tale of science gone wrong, a brilliant but mad scientist stitches together a patchwork of human body parts in a desperate attempt to create life. When his monstrous creation comes to life, it becomes a vengeful force beyond his control, leaving chaos and death in its wake. A chilling examination of man's hubris and the perils of playing God, this Gothic horror masterpiece serves as a cautionary reminder of the consequences of pushing the boundaries of science too far.
More Frankenstein- #84 of 375 onThe Best Movies Based On Books
- #155 of 397 onThe Best Horror Movies Of All Time
- #8 of 91 onThe 90 Best Black And White Movies
- 3Kiefer Sutherland, Julia Roberts, Kevin Bacon
A group of ambitious medical students embark on a dangerous game when they begin conducting clandestine experiments with near-death experiences, hoping to catch a forbidden glimpse of the great beyond. But as they push the limits of life and death further and further, the group finds themselves haunted by the vengeful spirits their experiments have awakened. A boundary-pushing examination of death and the supernatural, this chilling horror film taps into our deepest fears of the unknown.
More Flatliners- #44 of 252 onThe 200+ Best Psychological Thrillers Of All Time
- #503 of 769 onThe Most Rewatchable Movies
- #144 of 379 onThe Best Movies Of The 1990s
- 4Ben Kingsley, Michael Madsen, Alfred Molina
A top-secret government project aimed at creating the perfect human-alien hybrid takes a terrifying turn when the end result escapes confinement and embarks on a deadly hunt for the perfect mate. With humanity hanging in the balance, a crack team of specialists is assembled to track down and destroy the creature before it can reproduce. For fans of sci-fi horror, this intense thriller weaves a tale of genetic manipulation and extraterrestrial terror that will have you on the edge of your seat.
More Species- #54 of 178 onThe 150+ Best Movies With Aliens
- #236 of 397 onThe Best Horror Movies Of All Time
- #67 of 176 onThe Best Science Fiction Action Movies
- 5Maurice Dean Wint, Nicole de Boer, Nicky Guadagni
A group of strangers awakens to find themselves trapped inside a maze-like structure filled with deadly traps designed by a sadistic mastermind. As they struggle to navigate the treacherous labyrinth and decipher its cryptic clues, the group's desperation intensifies, sending them spiraling into paranoia and violence. With its nail-biting suspense and claustrophobic atmosphere, this cult horror film offers a twisted exploration of human experimentation and psychological torment.
More Cube- #105 of 252 onThe 200+ Best Psychological Thrillers Of All Time
- #248 of 379 onThe Best Movies Of The 1990s
- #193 of 397 onThe Best Horror Movies Of All Time
- 6Jeffrey Combs, Bruce Abbott, Barbara Crampton
In a sinister twist on the classic Frankenstein story, an ambitious medical student uncovers a secret serum that can reanimate the dead – but at an unspeakable cost. As the boundaries between life and death are blurred, he finds himself drawn into a grisly series of experiments that unleash unimaginable horrors. With its stomach-churning gore and darkly comedic undertones, this cult horror film explores the depths of depravity to which humans will sink in pursuit of their twisted ambitions.
More Re-Animator- #286 of 399 onThe Best Movies Of The 1980s, Ranked
- #27 of 125 onThe Top 100+ Zombie Movies Of All Time
- #253 of 397 onThe Best Horror Movies Of All Time
- 7Rufus Sewell, Kiefer Sutherland, Jennifer Connelly
Upon waking without memories in a sinister metropolis controlled by powerful psychics, a man quickly descends into the city's shadowy underworld to unravel the truth behind his identity and the malevolent forces at play. As the line between reality and illusion blurs, he discovers the cruel experiments being enacted upon the city's unsuspecting inhabitants. A gripping fusion of horror, sci-fi, and noir elements, this darkly atmospheric tale serves up a chilling exploration of mind control and sinister experimentation.
More Dark City- #125 of 252 onThe 200+ Best Psychological Thrillers Of All Time
- #45 of 166 onThe 150+ Best Futuristic Dystopian Movies
- #88 of 178 onThe 150+ Best Movies With Aliens
- 8Claude Rains, Gloria Stuart, Una O'Connor
In this bone-chilling adaptation of the classic novel, a brilliant scientist discovers a formula that enables him to become invisible at will. However, the newfound power soon corrupts him, driving him to commit increasingly vicious acts while evading the authorities' efforts to apprehend him. A gripping study of dangerous obsession and unchecked power, this starkly unsettling horror film will leave audiences questioning the limits of scientific experimentation.
More The Invisible Man- #221 of 375 onThe Best Movies Based On Books
- #302 of 397 onThe Best Horror Movies Of All Time
- #16 of 51 onThe Greatest Classic Sci-Fi Movies
- 9Mylène Jampanoï, Morjana El Alaoui, Xavier Dolan
In this harrowing French horror film, a traumatized woman embarks on a violent quest for revenge against the nihilistic cult that tormented her as a child. But when she discovers the group's chilling endgame – a series of brutal experiments designed to unlock the ultimate secrets of life and death – she is drawn into a horrific confrontation with the very nature of suffering itself. A gut-wrenching examination of the human capacity for cruelty, this brutal masterpiece is both an unforgettable exploration of sadistic experimentation and a searing indictment of our darkest desires.
More Martyrs- #31 of 125 onThe 100+ Grossest Movies Ever
- #328 of 397 onThe Best Horror Movies Of All Time
- #94 of 168 onThe 160+ Scariest Psychological Thrillers
- 10David Keith, Drew Barrymore, George C. Scott
When a young girl with pyrokinetic powers becomes the target of an unscrupulous government agency obsessed with harnessing her abilities for nefarious purposes, she and her father go on the run in a desperate bid to escape their clutches. Pursued by relentless agents and deadly assassins, the pair must rely on their wits – and the girl's fiery gifts – to overcome the evil forces out to exploit them. A riveting tale of psychic powers and the ruthless pursuit of power, this horror thriller will have you questioning the ethics of covert experimentation.
More Firestarter- #172 of 397 onThe Best Horror Movies Of All Time
- #33 of 92 onThe Best Movies Of 1984, Ranked
- #19 of 59 onThe 55+ Best Stephen King Movies
- 11Marilyn Chambers, Joe Silver, Susan Roman
In the aftermath of a gruesome motorcycle accident, a young woman undergoes an experimental surgery that inadvertently unleashes a monstrous hunger within her. As she prowls the streets in search of fresh victims, the city is plunged into a nightmarish epidemic. Filled with visceral shocks and Cronenberg's signature body horror, this gory classic is a stomach-churning exploration of the consequences of unbridled scientific ambition.
More Rabid- #76 of 125 onThe Top 100+ Zombie Movies Of All Time
- #32 of 49 onThe Best Horror Movies About Virus Outbreaks
- #20 of 32 onThe Best Dramas About Zombies
- 12Katharine Isabelle, Antonio Cupo, Tristan Risk
A disillusioned medical student finds herself drawn into the bizarre world of body modification surgery, eager to leave her mundane life behind and carve out a unique niche for herself. However, she soon discovers that her new clientele harbors dark secrets and twisted desires that threaten to drag her down into their macabre underworld. With its stylish visuals and twisted sensibility, this provocative horror film serves up a chilling exploration of the fetishization of the human body and the slippery slope of surgical experimentation.
More American Mary - 13Adrien Brody, Sarah Polley, Delphine Chaneac
When a pair of brilliant scientists embark on a top-secret project to create a revolutionary human-animal hybrid, they inadvertently unleash a genetic nightmare that threatens to spiral out of control. As the creature undergoes a terrifying metamorphosis, the duo must confront the moral and ethical implications of their experiment while attempting to contain the damage they have wrought. A thought-provoking meditation on the perils of unchecked scientific ambition, this haunting horror film offers a chilling exploration of the boundaries between humans and the beings we create.
More Splice - 14Domhnall Gleeson, Oscar Isaac, Alicia Vikander
A young programmer is invited to a reclusive tech mogul's secluded mountain estate to test the groundbreaking artificial intelligence of his latest creation – a stunningly lifelike female robot named Ava. But as the pair grows closer, the programmer discovers the horrifying truth behind the AI's creation and the sinister intentions of its creator. An intoxicating mix of sleek sci-fi, psychological thrills, and body horror, this chilling masterpiece offers a fascinating exploration of the ethics of AI experimentation and the ever-blurring line between man and machine.
More Ex Machina- #81 of 252 onThe 200+ Best Psychological Thrillers Of All Time
- #38 of 166 onThe 150+ Best Futuristic Dystopian Movies
- #11 of 63 onThe Greatest Directorial Debuts Of All Time
- 15Tobin Bell, Shawnee Smith, Cary Elwes
In this sadistic series of horror films, a deranged madman known as Jigsaw abducts his victims and subjects them to a series of brutal, meticulously constructed games designed to test the limits of their morality and survival instincts. Trapped in a grisly web of deceit and suffering, Jigsaw's captives must confront their darkest fears and deepest secrets in order to survive his twisted machinations. With its nightmarish scenarios and relentless tension, the Saw franchise serves as a chilling examination of human depravity and the lengths to which some will go in the name of twisted experimentation.
- 16William Hurt, Blair Brown, Bob Balaban
A brilliant scientist's reckless experiments with sensory deprivation and psychotropic drugs spiral out of control, leading him to confront the terrifying, primordial nature of human consciousness. As his grip on reality slips away, he becomes increasingly consumed by his quest for the ultimate truth – and the unthinkable horrors that lie within. A trippy blend of psychedelic visuals, unsettling atmosphere, and mind-bending philosophy, this cult horror film offers a hallucinatory journey through the darkest corners of the human mind.
More Altered States- #31 of 64 onThe Best Movies Of 1980
- #279 of 399 onThe Best Movies Of The 1980s, Ranked
- #74 of 97 onThe 90+ Best Drug Movies of All Time
- 17John Gallagher, Tony Goldwyn, Adria Arjona
In a twisted social experiment, 80 employees at a high-security office building are locked down and forced to participate in a grisly game of kill-or-be-killed by an unseen force. With their survival instincts pushed to the breaking point, the terrified workers turn on one another in a desperate bid to survive the night. A nerve-shredding descent into madness and savagery, this nail-biting horror thriller explores the darkest depths of human nature, challenging audiences to question just how far they would go to save themselves.
- 18Stephen Lack, Jennifer O'Neill, Patrick McGoohan
In a world where telepathic individuals known as Scanners are ruthlessly hunted by a shadowy organization, a renegade Scanner with unique powers emerges as humanity's last hope against the sinister forces that seek to exploit his kind. As he fights to expose the truth and protect the innocent, he faces an escalating series of deadly challenges that push him to the brink of his psychic abilities. A thrilling blend of action, sci-fi, and horror, this cult classic explores the darker aspects of human experimentation and the unscrupulous pursuit of power.
More Scanners- #306 of 399 onThe Best Movies Of The 1980s, Ranked
- #258 of 397 onThe Best Horror Movies Of All Time
- #22 of 75 onThe Best Movies Of 1981
- 19Taylor Russell, Logan Miller, Deborah Ann Woll
A group of strangers lured into a mysterious escape room experience quickly realize that the stakes are far higher than they'd anticipated, as the rooms become progressively more deadly and escape seems increasingly impossible. As they're forced to rely on one another and their wits to survive, they begin to uncover the disturbing truth behind their twisted ordeal. This gripping horror thriller takes the concept of human experimentation to terrifying new heights, examining the lengths to which some will go in pursuit of entertainment – and profit.
More Escape Room- #108 of 168 onThe 160+ Scariest Psychological Thrillers
- #2 of 11 on11 Thanksgiving Horror Movies That Carve Up More Than Just The Turkey
- #14 of 21 onThe Best Movies With Puzzles
- 20Fabiana Udenio, Jeffrey Combs, Kathleen Kinmont
In this sequel to the cult horror classic Re-Animator, the deranged doctor returns with a new, even more twisted scheme to conquer death: the creation of a female companion for his monstrous first experiment. But as he sets about assembling his grotesque bride from a patchwork of body parts, he unwittingly unleashes a torrent of bloody chaos that threatens to overwhelm him. With its wild mix of gory shocks, dark humor, and macabre delights, this campy horror-comedy offers a wickedly entertaining look at the sinister consequences of unchecked scientific ambition.
- 21Michael Madsen, Natasha Henstridge, Marg Helgenberger
In this pulse-pounding sequel to the hit sci-fi horror film, a group of astronauts returns from a mission to Mars bearing a deadly extraterrestrial virus that transforms its host into a monstrous, alien-human hybrid. As the contagion spreads, humanity's only hope for survival lies in the hands of a crack team of specialists tasked with tracking down the infected and eliminating the threat before it can consume the Earth. A thrilling ride through the horrors of biological warfare and unchecked scientific ambition, this action-packed film offers up a terrifying vision of humanity on the brink of apocalypse.
More Species II- #169 of 178 onThe 150+ Best Movies With Aliens
- #34 of 62 onThe Best Alien Horror Movies Ever Made
- #74 of 91 onThe 90+ Best '90s Sci-Fi Movies, Ranked
- 22Charlton Heston, Edward G. Robinson, Leigh Taylor-Young
In a dystopian future where overpopulation, pollution, and resource depletion have plunged the Earth into crisis, a detective unravels the horrifying secret behind the world's most popular food: Soylent Green. As he delves deeper into the conspiracy, he must confront the ghastly truth about humanity's desperate attempts to sustain itself in the face of impending collapse. A chilling exploration of environmental degradation and the terrifying lengths to which mankind will go in the name of survival, this classic sci-fi horror film serves as a sobering reminder of the consequences of uncontrolled scientific experimentation.
More Soylent Green- #322 of 769 onThe Most Rewatchable Movies
- #42 of 166 onThe 150+ Best Futuristic Dystopian Movies
- #72 of 199 onThe Best Movies Of The '70s, Ranked
- 23Gregory Peck, Laurence Olivier, James Mason
A relentless Nazi-hunter uncovers a terrifying plot to resurrect the Third Reich by cloning Adolf Hitler, masterminded by a group of exiled war criminals in South America. As he races against time to thwart their diabolical scheme, he must confront the chilling possibility that history could be doomed to repeat itself. A gripping fusion of historical thriller and sci-fi horror, this unsettling film offers a chilling exploration of the ethics of cloning and the unsettling legacy of WWII-era experimentation.
More The Boys from Brazil- #105 of 199 onThe Best Movies Of The '70s, Ranked
- #23 of 37 onThe Best Movies About Clones That'll Make You See Double
- #243 of 404 onThe 300+ Best Sci-Fi Movies Of All Time
- 24
The Lazarus Effect
Mark Duplass, Olivia Wilde, Donald GloverA group of researchers' groundbreaking experiments with resuscitation technology spiral out of control when they successfully revive a deceased colleague, unleashing a malevolent and supernatural force that threatens to consume them all. As they struggle to contain the unleashed evil, they must confront the chilling ramifications of their groundbreaking work and the perilous consequences of playing God. A tense and atmospheric blend of science fiction and horror, this chilling film offers a haunting exploration of the ethical boundaries of medical research and the eternal mysteries of life and death.
- 25Song Kang-ho, Byun Hee-bong, Park Hae-il
In this acclaimed monster movie, a bizarre creature born from the eco-disaster wreaked by a reckless laboratory emerges from Seoul's Han River to terrorize the city and abduct a young girl. As her dysfunctional family bands together to save her from the monster's clutches, they must contend with government agents and their own personal demons to uncover the truth behind the creature's origins. A thrilling blend of action, horror, and social commentary, this chilling film offers a scathing indictment of environmental negligence and the hazards of unchecked scientific progress.
More The Host- #197 of 425 onThe Greatest Movies in World Cinema History
- #274 of 397 onThe Best Horror Movies Of All Time
- #47 of 101 onThe Best Movies Of 2006
- 26Jeffrey Combs, Barbara Crampton, Ted Sorel
When a brilliant scientist's experiments with interdimensional communication inadvertently open a doorway to a terrifying alternate reality, he and his colleagues find themselves caught in a nightmare world populated by grotesque creatures and unimaginable horrors. As they struggle to survive and find a way back home, they must confront the grim consequences of their reckless quest for knowledge. A spine-tingling descent into Lovecraftian cosmic horror, this chilling film explores the dangers of unchecked scientific curiosity and mankind's fragile place in the universe.
More From Beyond- #326 of 397 onThe Best Horror Movies Of All Time
- #6 of 14 onPretty Good Horror Movies That Get Under Your Skin
- #2 of 23 onThe Best Cosmic Horror Movies That Will Warp Your Mind
- 27Marshall Thompson, Michael Balfour, Kynaston Reeves
An ambitious scientist's experiments with telekinesis unintentionally give rise to invisible, brain-sucking creatures that terrorize a small town. As the death toll rises, the desperate locals must band together to stop the fiends before they consume everyone in their path. A thrilling blend of classic monster movie tropes and Cold War-era paranoia, this chilling horror film offers a cautionary tale about the dangers of scientific hubris and meddling with the unknown.
- 28
Raw
Garance Marillier, Ella Rumpf, Rabah Nait OufellaWhen a sheltered vegetarian veterinary student is forced to consume animal flesh as part of a hazing ritual, she develops a gruesome hunger for human flesh that threatens to consume her very identity. As her insatiable cravings escalate, she finds herself drawn into a macabre world where food, sex, and violence collide, forcing her to confront the horrifying truth about her own nature. A visceral exploration of the human appetite for taboo, this gut-churning body horror film serves up a grisly feast for fans of extreme cinema.
More Raw - 29Ashley C. Williams, Dieter Laser, Akihiro Kitamura
In this notorious body horror film, a deranged surgeon kidnaps three tourists and subjects them to a gruesome experiment, sewing them together mouth-to-anus to create a single, grotesque organism. As the horrific reality of their situation sinks in, the victims must grapple with the full extent of their captor's sadistic depravity and fight for their survival. With its unflinching brutality and stomach-churning premise, this shocking film serves as a horrifying exploration of human cruelty and the twisted depths of medical experimentation.
- 30
Tusk
Michael Parks, Justin Long, Haley Joel OsmentIn this twisted horror-comedy, a self-obsessed podcaster finds himself the unwitting subject of a demented man's grotesque experiment, as he is surgically transformed into a monstrous walrus-human hybrid. As his friends race to find and rescue him, the podcaster must come to terms with his hideous new form and confront the deranged captor who holds his life in his hands. A bizarre and unsettling exploration of the boundaries between man and beast, this darkly humorous film serves as a savage critique of our human obsession with body modification and the darker aspects of our fascination with the animal kingdom.
More Tusk
