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  • #1

    long term use of doxycycline

    hi all, i'm new to this forum but have had rosacea for at least 15 years. thanks to all for the great advice.

    i had a really bad breakout of redness on my forehead about 5 days ago. i started taking my old doxycycline pills again which have always worked well in the past and again, they worked well, i'm looking a lot better now.

    i can just keep taking the pills indefinitely i suppose but i worry about the long term effects of antibiotic use. any thoughts about this?

    thanks, steve
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  • #2
    Hi Steve,

    What dose of doxy are you currently taking and how old are the pills?
    You want to make sure they did not expire as that can cause problems.

    I would suggest you check out Oracea which is low dose doxy (40 mg timed release) and can be safely taken for long periods of time (as far as we all know right now). It acts as an anti-inflammatory and has no microbial properties.

    Welcome to the RF

    Best wishes,
    Melissa

    Comment

    • #3
      Steve,

      among other reasons, longterm AB use is really hard on your GI. For example nausea, upset stomach, etc. I actually became lactose intolerant when on doxy for a long period of time (thankfully it reversed itself when i stopped taking the drug).

      So those side effects, plus drug resistance, i think is what they're trying to avoid with long term AB usage.

      Comment

      • #4
        Originally posted by mutantfrog View Post
        Steve,

        among other reasons, longterm AB use is really hard on your GI. For example nausea, upset stomach, etc. I actually became lactose intolerant when on doxy for a long period of time (thankfully it reversed itself when i stopped taking the drug).

        So those side effects, plus drug resistance, i think is what they're trying to avoid with long term AB usage.
        That's why taking a submicrobial dose is so attractive if it is effective for you.

        Comment

        • #5
          Originally posted by Melissa W View Post
          Hi Steve,

          What dose of doxy are you currently taking and how old are the pills?
          You want to make sure they did not expire as that can cause problems.

          I would suggest you check out Oracea which is low dose doxy (40 mg timed release) and can be safely taken for long periods of time (as far as we all know right now). It acts as an anti-inflammatory and has no microbial properties.

          Welcome to the RF

          Best wishes,
          Melissa
          hi Melissa

          thanks for the info, i take 2 pills/day 100mg each. they are very effective, most of my redness is gone in about 6-7 days. they are about 6 months old i guess. i get them over the counter in Bangkok (I live in Thailand).

          i can try Oracea if i can find them.

          thanks, steve

          Comment

          • #6
            I wouldnt recommend long term usage of such a high dose. You can become resistant to the medication and then when you really need it for health concerns, it won't work. Plus your liver has to process it, and who knows what all that med long term can do in that sense.

            Go for the Oracea for sure. Or even something called Periostat (exact same thing as Oracea, just different name).

            Comment

            • #7
              If you don't have access to Oracea or Periostat you can try 50 mg doxy once a day. That is similar to Oracea and Periostat will not be as hard on your body (liver and kidneys) as 100 mg doxy twice a day. The anti-inflammatory effect is all you need for rosacea usually.

              Comment

              • #8
                Long term use of doxycycline

                I have been using doxy 100 mgs a day for about a year now. My opthamologist prescribed it for dryness in my eyes due to rosacea. Somehow it stimulates the oil glands to produce more oil. It seems to work well, but I am concerned about the effects of taking this long term. I recently have had some issues with my gastrointestinal system and had a colonoscopy which showed some irritation but otherwise normal - nothing to be treated for. Also my rheumatoid factor was elevated on some bloodwork which I was told could be from the doxy - again, nothing to worry about, but I am wondering if I should be concerned. Any ideas out there?

                Comment

                • #9
                  Have you spoken to your internist/gp about this?

                  It would be preferable if you could switch to a lower dose of doxy of course so I wonder if you could try that and see how you do. You may get just as good ocular effects from the 50 mg doxy as you do from the 100 mg doxy.

                  Best wishes,
                  Melissa

                  Comment

                  • #10
                    Long term use of doxy

                    Thank you - I do have an appt. with my internist in two weeks and will definitely bring it up. Also with my eye dr. in August and will ask about a lower dose. Other than the doxy, have you heard of anything else to treat that gritty dry feeling successfully?

                    Comment

                    • #11
                      Lid massages might help stimulate oil production and there are other treatments to try that may be helpful. Read this sticky as there is a lot of info in it you may find useful.

                      http://www.rosaceagroup.org/The_Rosacea_Forum/showthread.php?t=15902


                      Best wishes,
                      Melissa

                      Comment

                      • #12
                        I looked into Oracea and it is quite expensive. You can take 20mg Doxy twice a day to come close to simulating Oracea. It's cheaper than Oracea but still not good. I am going to ask my doctor for larger dose pills and get a pill splitter to make it even cheaper.

                        Comment

                        • #13
                          Originally posted by amhinz View Post
                          Thank you - I do have an appt. with my internist in two weeks and will definitely bring it up. Also with my eye dr. in August and will ask about a lower dose. Other than the doxy, have you heard of anything else to treat that gritty dry feeling successfully?
                          There are many treatments you can try. If you read the links I gave you it is all there but here is a sampling:

                          Lid massages; Restasis eye drops (Rx) twice a day; preservative free rewetting drops throughout the day; adding omega 3's to your diet in the form of oily fish and flaxseed to name a few. It all depends on the cause of your gritty dry eyes. If you read the ocular resources sticky there are some excellent articles explaining all of this and more. Best of luck on your appt.

                          Melissa

                          Comment

                          • #14
                            update:

                            I can't believe the cost advantage of using 100mg Doxy tablets and a pill splitter. Before I was taking 20mg tablets twice a day, that dosing cost nearly a $2 a day. I just got 60 100mg tablets for $8. Taking 25mg twice a day puts the cost at $0.07 a dayl!!!!!!!!!!

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