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David Caruso stars as Police Lieutenant Horatio Caine, a streetwise bomb disposal expert with special knowledge in explosive forensics. Along with his elite investigative team—ballistics specialist Calleigh Duquesne (Emily Proctor), fingerprint and drug expert Eric Delco (Adam Rodriguez), Lt. Megan Donner (Kim Delaney), and medical examiner Alexx Woods (Khandi Alexander)—Caine uses his razor-sharp instinct to solve Miami's toughest cases and bring those responsible to justice.