Johnny Depp (Frank Tupelo), Angelina Jolie (Elise Clifton-Ward), Paul Bettany (Inspector John Acheson), Timothy Dalton (Chief Inspector Jones), Steven Berkoff (Reginald Shaw), Rufus Sewell (The Englishman), Christian De Sica (Colonnello Lombardi) more..., Alessio Boni (Sergente Cerato), Daniele Pecci (Tenente Narduzzi), Giovanni Guidelli (Tenente Tommassini), Raoul Bova (Conte Filippo Gaggia), Bruno Wolkowitch (Capitaine Courson), Julien Baumgartner (Brigadier Ricuort), François Vincentelli (Brigadier Marion), Clément Sibony (Brigadier Rousseau), Jean-Claude Adelin (Brigadier Cavillan), Jean-Marie Lamour (Cafe Waiter Jean-Michel), Nicolas Guillot (Cafe Head Waiter Jérôme), Mhamed Arezki (Courier Achmed Tchebali), Igor Jijikine (Virginsky), Vladimir Orlov (Lebyadkin), Vladimir Tevlovski (Liputin), Alec Utgoff (Fedka), Mark Zak (Shigalyov), Neri Marcorè (Hotel Concierge Alessio), Gabriele Gallinari (Hotel Bell Boy Luca), Riccardo De Torrebruna (Hotel Waiter Guido), Maurizio Casagrande (Waiter Antonio), Nino Frassica (Brigadiere Mele), Gwilym Lee (Senior Technician Mountain), Steven Robertson (Junior Technician Pinnock), Iddo Goldberg (Jones' Assistant Whitfield), Renato Scarpa (Arturo the Tailor), Giancarlo Previati (Gala Coordinator Dalla Pietà), Giovanni Esposito (Interpreter Coppa), Marino Narduzzi (Elise's Driver Stefano), Tino Giada (Elise's Driver Mauro), Bruno Bilotta (Sniper Chief Giordani), Ralf Moeller (Jail Bird Lunt), Marc Ruchmann (Brigadier Kaiser) and others.

James Newton Howard (Original Music Composer), Florian Henckel von Donnersmarck (Screenplay), Julian Fellowes (Screenplay), Jérôme Salle (Original Story), Christopher McQuarrie (Screenplay), Colleen Atwood (Costume Design), Gary Barber (Producer) more..., Roger Birnbaum (Producer), Jonathan Glickman (Producer), Tim Headington (Producer), Graham King (Producer), Susie Figgis (Casting), John Seale (Director of Photography), Joe Hutshing (Editor), Patricia Rommel (Editor), Jon Hutman (Production Design), Susanna Codognato (Art Direction), Anna Pinnock (Set Decoration), Suzi Turnbull (Costume Supervisor), Marco Trentini (Supervising Art Director), Denis O'Sullivan (Co-Producer), Adam Rosenberg (Producer), Olivier Courson (Executive Producer), Ron Halpern (Executive Producer), John Bernard (Line Producer), Jeffrey Nachmanoff (Co-Producer), David Nichols (Line Producer), Bahman Naraghi (Executive Producer), Lloyd Phillips (Executive Producer), Giorgio Gregorini (Hair Designer), Peter Nicastro (Hairstylist), Veronica McAleer (Hairstylist), Karen Asano-Myers (Hairstylist), Colin Jamison (Hairstylist), Fulvio Pozzobon (Key Hair Stylist), Frédérique Arguello (Key Hair Stylist), Maurizio Silvi (Key Makeup Artist), Françoise Quilichini (Key Makeup Artist), Novella Borghi (Makeup Artist), Joel Harlow (Makeup Artist) and others.