- Denzel Washington
- John Q. Archibald
- Robert Duvall
- Grimes
- James Woods
- Dr. Turner
- Anne Heche
- Rebecca Payne
- Eddie Griffin
- Lester
- Kimberly Elise
- Denise Archibald
- Shawn Hatosy
- Mitch
- Ray Liotta
- Monroe
- Daniel E. Smith
- Michael 'Mike' Archibald
- David Thornton
- Jimmy Palumbo
- Ethan Suplee
- Max
- Kevin Connolly
- Steve Maguire
- Paul Johansson
- Tuck Lampley
- Heather Wahlquist
- Julie
- Troy Byer
- Miriam
- Obba Babatundé
- Sgt. Moody
- Troy Winbush
- Steve
- Laura Harring
- Gina Palumbo
- Larissa Laskin
- Dr. Klein
- Dina Spybey-Waters
- Debby Utley
- Martha Chaves
- Rosa Gonzales
- Nick Cassavetes
- Director
- James Kearns
- Writer
- Mark Burg
- Producer
- Oren Koules
- Producer
- Avram "Butch" Kaplan
- Executive Producer, Unit Production Manager
- Richard Saperstein
- Executive Producer
- Michael De Luca
- Executive Producer
- Rogier Stoffers
- Cinematographer
- Stefania Cella
- Production Design
- Dede Allen
- Film Editing
- Aaron Zigman
- Original Music
- Beatrix Aruna Pasztor
- Costume Design
- Matthew Barry
- Casting
- Nancy Green-Keyes
- Casting
- Matthew Carnegie
- Art Director
- Elis Lam
- Art Director
- Mathew Hart
- Unit Production Manager
- William M. Connor
- First Assistant Director
- Tony Kenny
- Special Effects Supervisor
