Take bus A21 right at the airport to Yau Ma Tei; Get off at Man Ming Lane bus stop (either the bus driver will announce the bus stop name or you can see it in the list inside the bus). Get off and keep walking until you see 7-11 store on your left. Make a left turn at 7-11 and you can see the hotel in front of you about 30 meters from Nathan Rd. Very convenient. Remember HK drives on the left and the bus stop is on the left of the road. To return to the airport go across the street and the bus runs overnight and early morning. I've been to HK almost each year.

I don't know if they allow you to check out late. Remember, you can check out before 12:00pm and store your luggage in the store room at the lobby. They are very strict with number of occupants and check-in and out time. I once got there around 12pm, I have to store my luggage at the hotel and came back around 2:00pm to check in.

Yes - I am a woman in my early 40s and stayed with my mother in her 70s and we felt perfectly safe in the area and hotel. Its an older hotel but we had no issues with cleanliness.

There are a number of options from HK airport. The cheapest is the A21 Airport Bus for HKD33 which takes an hour to Tsim Sha Tsui, Kowloon. So if your hotel is along Nathan Rd use this as is comfy and direct. I believe the other A22 goes to the main island but I'm not sure so check online. The faster option is the MTR train to the Kowloon stn, a lot more expensive. There are also hotel airport buses so check with your hotel first if they run any. Taxis are also an option, but not cheap, unless you're staying in a way-out location not served by public transport. Gary