Cyamemazine
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Identification
- Generic Name
- Cyamemazine
- DrugBank Accession Number
- DB09000
- Background
Cyamemazine (Tercian), also known as cyamepromazine, is a typical antipsychotic drug of the phenothiazine class used primarily in the treatment of schizophrenia and psychosis-associated anxiety. Cyamemazine actually behaves like an atypical antipsychotic, due to its potent anxiolytic effects (5-HT2C) and lack of extrapyramidal side effects (5-HT2A).
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 323.455
Monoisotopic: 323.145618377 - Chemical Formula
- C19H21N3S
- Synonyms
- Cyamemazine
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
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- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your software1,2-Benzodiazepine The risk or severity of CNS depression can be increased when Cyamemazine is combined with 1,2-Benzodiazepine. Acebutolol The serum concentration of Acebutolol can be increased when it is combined with Cyamemazine. Acetazolamide The risk or severity of CNS depression can be increased when Acetazolamide is combined with Cyamemazine. Acetohexamide The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Cyamemazine. Acetophenazine The risk or severity of CNS depression can be increased when Acetophenazine is combined with Cyamemazine. Agomelatine The risk or severity of CNS depression can be increased when Agomelatine is combined with Cyamemazine. Alfentanil The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Alfentanil. Alimemazine The risk or severity of CNS depression can be increased when Alimemazine is combined with Cyamemazine. Almasilate Almasilate can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy. Almotriptan The risk or severity of adverse effects can be increased when Almotriptan is combined with Cyamemazine. Alosetron The risk or severity of CNS depression can be increased when Alosetron is combined with Cyamemazine. Alprazolam The risk or severity of CNS depression can be increased when Alprazolam is combined with Cyamemazine. Aluminium Aluminium can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy. Aluminium phosphate Aluminium phosphate can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy. Aluminum hydroxide Aluminum hydroxide can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy. Alverine The risk or severity of CNS depression can be increased when Alverine is combined with Cyamemazine. Amisulpride Cyamemazine may increase the antipsychotic activities of Amisulpride. Amitriptyline The serum concentration of Amitriptyline can be increased when it is combined with Cyamemazine. Amitriptylinoxide The serum concentration of Amitriptylinoxide can be increased when it is combined with Cyamemazine. Amobarbital The risk or severity of CNS depression can be increased when Amobarbital is combined with Cyamemazine. Amodiaquine The risk or severity of QTc prolongation can be increased when Amodiaquine is combined with Cyamemazine. Amoxapine The serum concentration of Amoxapine can be increased when it is combined with Cyamemazine. Amphetamine Cyamemazine may decrease the stimulatory activities of Amphetamine. Apomorphine The risk or severity of CNS depression can be increased when Apomorphine is combined with Cyamemazine. Apronalide The risk or severity of CNS depression can be increased when Cyamemazine is combined with Apronalide. Aripiprazole The risk or severity of CNS depression can be increased when Aripiprazole is combined with Cyamemazine. Aripiprazole lauroxil The risk or severity of CNS depression can be increased when Cyamemazine is combined with Aripiprazole lauroxil. Artemether The risk or severity of QTc prolongation can be increased when Artemether is combined with Cyamemazine. Artemotil The risk or severity of QTc prolongation can be increased when Artemotil is combined with Cyamemazine. Artenimol The risk or severity of QTc prolongation can be increased when Artenimol is combined with Cyamemazine. Artesunate The risk or severity of QTc prolongation can be increased when Artesunate is combined with Cyamemazine. Articaine The risk or severity of CNS depression can be increased when Cyamemazine is combined with Articaine. Asenapine The risk or severity of CNS depression can be increased when Asenapine is combined with Cyamemazine. Atenolol The serum concentration of Atenolol can be increased when it is combined with Cyamemazine. Atovaquone The risk or severity of QTc prolongation can be increased when Atovaquone is combined with Cyamemazine. Atracurium The risk or severity of CNS depression can be increased when Cyamemazine is combined with Atracurium. Atracurium besylate The risk or severity of CNS depression can be increased when Atracurium besylate is combined with Cyamemazine. Azelastine Cyamemazine may increase the central nervous system depressant (CNS depressant) activities of Azelastine. Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine. Benperidol The risk or severity of CNS depression can be increased when Cyamemazine is combined with Benperidol. Benzhydrocodone The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Benzhydrocodone. Benzocaine The risk or severity of CNS depression can be increased when Benzocaine is combined with Cyamemazine. Benzphetamine Cyamemazine may decrease the stimulatory activities of Benzphetamine. Benzyl alcohol The risk or severity of CNS depression can be increased when Benzyl alcohol is combined with Cyamemazine. Betaxolol The serum concentration of Betaxolol can be increased when it is combined with Cyamemazine. Bismuth subcitrate potassium Cyamemazine may increase the neurotoxic activities of Bismuth subcitrate potassium. Bismuth subgallate Cyamemazine may increase the neurotoxic activities of Bismuth subgallate. Bismuth subnitrate Bismuth subnitrate can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy. Bisoprolol The serum concentration of Bisoprolol can be increased when it is combined with Cyamemazine. Botulinum toxin type A The risk or severity of CNS depression can be increased when Botulinum toxin type A is combined with Cyamemazine. Botulinum toxin type B The risk or severity of CNS depression can be increased when Botulinum toxin type B is combined with Cyamemazine. Brexanolone The risk or severity of CNS depression can be increased when Cyamemazine is combined with Brexanolone. Brexpiprazole The risk or severity of CNS depression can be increased when Cyamemazine is combined with Brexpiprazole. Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine. Brivaracetam The risk or severity of CNS depression can be increased when Brivaracetam is combined with Cyamemazine. Bromazepam The risk or severity of CNS depression can be increased when Bromazepam is combined with Cyamemazine. Bromocriptine The risk or severity of adverse effects can be increased when Bromocriptine is combined with Cyamemazine. Bromperidol The risk or severity of CNS depression can be increased when Cyamemazine is combined with Bromperidol. Brompheniramine The risk or severity of CNS depression can be increased when Brompheniramine is combined with Cyamemazine. Bupivacaine The risk or severity of CNS depression can be increased when Bupivacaine is combined with Cyamemazine. Buprenorphine Cyamemazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. Bupropion The risk or severity of CNS depression can be increased when Bupropion is combined with Cyamemazine. Buspirone The risk or severity of CNS depression can be increased when Buspirone is combined with Cyamemazine. Butabarbital The risk or severity of CNS depression can be increased when Butabarbital is combined with Cyamemazine. Butalbital The risk or severity of CNS depression can be increased when Butalbital is combined with Cyamemazine. Butaperazine The risk or severity of CNS depression can be increased when Cyamemazine is combined with Butaperazine. Butobarbital The risk or severity of CNS depression can be increased when Butobarbital is combined with Cyamemazine. Butorphanol The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Butorphanol. Butriptyline The serum concentration of Butriptyline can be increased when it is combined with Cyamemazine. Cabergoline The risk or severity of adverse effects can be increased when Cabergoline is combined with Cyamemazine. Calcium carbonate Calcium carbonate can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy. Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Cyamemazine. Carbamazepine The risk or severity of CNS depression can be increased when Carbamazepine is combined with Cyamemazine. Carbinoxamine The risk or severity of CNS depression can be increased when Carbinoxamine is combined with Cyamemazine. Cariprazine The risk or severity of CNS depression can be increased when Cariprazine is combined with Cyamemazine. Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Cyamemazine. Carvedilol The serum concentration of Carvedilol can be increased when it is combined with Cyamemazine. Celiprolol The serum concentration of Celiprolol can be increased when it is combined with Cyamemazine. Cetirizine The risk or severity of CNS depression can be increased when Cetirizine is combined with Cyamemazine. Chloral hydrate The risk or severity of CNS depression can be increased when Chloral hydrate is combined with Cyamemazine. Chlordiazepoxide The risk or severity of CNS depression can be increased when Chlordiazepoxide is combined with Cyamemazine. Chlormezanone The risk or severity of CNS depression can be increased when Chlormezanone is combined with Cyamemazine. Chloroprocaine The risk or severity of CNS depression can be increased when Chloroprocaine is combined with Cyamemazine. Chloroquine The risk or severity of QTc prolongation can be increased when Chloroquine is combined with Cyamemazine. Chlorpheniramine The risk or severity of adverse effects can be increased when Chlorpheniramine is combined with Cyamemazine. Chlorpromazine The risk or severity of CNS depression can be increased when Chlorpromazine is combined with Cyamemazine. Chlorpropamide The therapeutic efficacy of Chlorpropamide can be decreased when used in combination with Cyamemazine. Chlorprothixene The risk or severity of CNS depression can be increased when Chlorprothixene is combined with Cyamemazine. Chlorzoxazone The risk or severity of CNS depression can be increased when Chlorzoxazone is combined with Cyamemazine. Cinchocaine The risk or severity of CNS depression can be increased when Cinchocaine is combined with Cyamemazine. Cisapride The risk or severity of CNS depression can be increased when Cisapride is combined with Cyamemazine. Cisatracurium The risk or severity of CNS depression can be increased when Cisatracurium is combined with Cyamemazine. Citalopram The risk or severity of adverse effects can be increased when Cyamemazine is combined with Citalopram. Clemastine The risk or severity of CNS depression can be increased when Clemastine is combined with Cyamemazine. Clidinium The risk or severity of CNS depression can be increased when Clidinium is combined with Cyamemazine. Clindamycin Clindamycin may increase the neurotoxic activities of Cyamemazine. Clobazam The risk or severity of sedation, somnolence, and CNS depression can be increased when Clobazam is combined with Cyamemazine. Clomipramine The serum concentration of desmethylclomipramine, an active metabolite of Clomipramine, can be increased when used in combination with Cyamemazine. Clonazepam The risk or severity of CNS depression can be increased when Clonazepam is combined with Cyamemazine. Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Cyamemazine. Clorazepic acid The risk or severity of CNS depression can be increased when Clorazepic acid is combined with Cyamemazine. Clothiapine The risk or severity of CNS depression can be increased when Cyamemazine is combined with Clothiapine. Clotiazepam The risk or severity of CNS depression can be increased when Clotiazepam is combined with Cyamemazine. Clozapine The risk or severity of CNS depression can be increased when Clozapine is combined with Cyamemazine. Codeine The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Codeine. Cyclizine The risk or severity of CNS depression can be increased when Cyclizine is combined with Cyamemazine. Cyclobenzaprine The risk or severity of CNS depression can be increased when Cyclobenzaprine is combined with Cyamemazine. Cycloguanil The risk or severity of QTc prolongation can be increased when Cycloguanil is combined with Cyamemazine. Cyclophosphamide Cyclophosphamide may increase the neurotoxic activities of Cyamemazine. Cycloserine Cycloserine may increase the neurotoxic activities of Cyamemazine. Cyclosporine Cyclosporine may increase the neurotoxic activities of Cyamemazine. Cyproheptadine The risk or severity of CNS depression can be increased when Cyproheptadine is combined with Cyamemazine. Dantrolene The risk or severity of CNS depression can be increased when Dantrolene is combined with Cyamemazine. Dapsone The risk or severity of QTc prolongation can be increased when Dapsone is combined with Cyamemazine. Daridorexant The risk or severity of CNS depression can be increased when Cyamemazine is combined with Daridorexant. Decamethonium The risk or severity of CNS depression can be increased when Decamethonium is combined with Cyamemazine. Desflurane The risk or severity of CNS depression can be increased when Desflurane is combined with Cyamemazine. Desipramine The serum concentration of Desipramine can be increased when it is combined with Cyamemazine. Desloratadine The risk or severity of CNS depression can be increased when Desloratadine is combined with Cyamemazine. Desvenlafaxine The risk or severity of adverse effects can be increased when Cyamemazine is combined with Desvenlafaxine. Deutetrabenazine The risk or severity of adverse effects can be increased when Cyamemazine is combined with Deutetrabenazine. Dexbrompheniramine The risk or severity of CNS depression can be increased when Dexbrompheniramine is combined with Cyamemazine. Dexmedetomidine The risk or severity of CNS depression can be increased when Dexmedetomidine is combined with Cyamemazine. Dexmethylphenidate The risk or severity of adverse effects can be increased when Cyamemazine is combined with Dexmethylphenidate. Dextroamphetamine Cyamemazine may decrease the stimulatory activities of Dextroamphetamine. Dextromethorphan The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Cyamemazine. Dextropropoxyphene The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Dextropropoxyphene. Dezocine The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Dezocine. Diamorphine The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Diamorphine. Diazepam The risk or severity of CNS depression can be increased when Diazepam is combined with Cyamemazine. Dibenzepin The serum concentration of Dibenzepin can be increased when it is combined with Cyamemazine. Dichloralphenazone The risk or severity of CNS depression can be increased when Dichloralphenazone is combined with Cyamemazine. Didanosine Didanosine may increase the neurotoxic activities of Cyamemazine. Diethylpropion Cyamemazine may decrease the stimulatory activities of Diethylpropion. Difenoxin The risk or severity of CNS depression can be increased when Difenoxin is combined with Cyamemazine. Dihydrocodeine The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Dihydrocodeine. Dihydroergotamine The risk or severity of adverse effects can be increased when Dihydroergotamine is combined with Cyamemazine. Dimenhydrinate The risk or severity of CNS depression can be increased when Dimenhydrinate is combined with Cyamemazine. Diphenhydramine The risk or severity of CNS depression can be increased when Diphenhydramine is combined with Cyamemazine. Diphenoxylate The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Diphenoxylate. Dolasetron The risk or severity of CNS depression can be increased when Dolasetron is combined with Cyamemazine. Donepezil The risk or severity of CNS depression can be increased when Donepezil is combined with Cyamemazine. Dosulepin The serum concentration of Dosulepin can be increased when it is combined with Cyamemazine. Doxacurium The risk or severity of CNS depression can be increased when Doxacurium is combined with Cyamemazine. Doxepin The serum concentration of Doxepin can be increased when it is combined with Cyamemazine. Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine. Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine. Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine. Duloxetine The risk or severity of adverse effects can be increased when Cyamemazine is combined with Duloxetine. Dyclonine The risk or severity of CNS depression can be increased when Dyclonine is combined with Cyamemazine. Efavirenz The risk or severity of CNS depression can be increased when Efavirenz is combined with Cyamemazine. Eletriptan The risk or severity of adverse effects can be increased when Eletriptan is combined with Cyamemazine. Eluxadoline The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Eluxadoline. Enflurane The risk or severity of CNS depression can be increased when Enflurane is combined with Cyamemazine. Entacapone The risk or severity of CNS depression can be increased when Entacapone is combined with Cyamemazine. Epinastine The risk or severity of CNS depression can be increased when Epinastine is combined with Cyamemazine. Ergoloid mesylate The risk or severity of adverse effects can be increased when Ergoloid mesylate is combined with Cyamemazine. Ergometrine The risk or severity of adverse effects can be increased when Ergometrine is combined with Cyamemazine. Ergotamine The risk or severity of adverse effects can be increased when Ergotamine is combined with Cyamemazine. Escitalopram The risk or severity of adverse effects can be increased when Cyamemazine is combined with Escitalopram. Esketamine The risk or severity of adverse effects can be increased when Cyamemazine is combined with Esketamine. Eslicarbazepine The risk or severity of CNS depression can be increased when Cyamemazine is combined with Eslicarbazepine. Eslicarbazepine acetate The risk or severity of CNS depression can be increased when Cyamemazine is combined with Eslicarbazepine acetate. Esmolol The serum concentration of Esmolol can be increased when it is combined with Cyamemazine. Estazolam The risk or severity of CNS depression can be increased when Estazolam is combined with Cyamemazine. Eszopiclone The risk or severity of CNS depression can be increased when Cyamemazine is combined with Eszopiclone. Ethanol Cyamemazine may increase the central nervous system depressant (CNS depressant) activities of Ethanol. Ethchlorvynol The risk or severity of CNS depression can be increased when Ethchlorvynol is combined with Cyamemazine. Ethosuximide The risk or severity of CNS depression can be increased when Ethosuximide is combined with Cyamemazine. Ethotoin The risk or severity of CNS depression can be increased when Ethotoin is combined with Cyamemazine. Etomidate The risk or severity of CNS depression can be increased when Etomidate is combined with Cyamemazine. Ezogabine The risk or severity of CNS depression can be increased when Ezogabine is combined with Cyamemazine. Felbamate The risk or severity of CNS depression can be increased when Felbamate is combined with Cyamemazine. Fenfluramine The risk or severity of CNS depression can be increased when Fenfluramine is combined with Cyamemazine. Fentanyl The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Fentanyl. Flibanserin The risk or severity of CNS depression can be increased when Flibanserin is combined with Cyamemazine. Flunarizine The risk or severity of CNS depression can be increased when Flunarizine is combined with Cyamemazine. Flunitrazepam The risk or severity of CNS depression can be increased when Flunitrazepam is combined with Cyamemazine. Fluoxetine Cyamemazine may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine. Flupentixol The risk or severity of CNS depression can be increased when Flupentixol is combined with Cyamemazine. Fluphenazine The risk or severity of CNS depression can be increased when Fluphenazine is combined with Cyamemazine. Flurazepam The risk or severity of CNS depression can be increased when Flurazepam is combined with Cyamemazine. Fluspirilene The risk or severity of CNS depression can be increased when Fluspirilene is combined with Cyamemazine. Fluticasone propionate The risk or severity of CNS depression can be increased when Fluticasone propionate is combined with Cyamemazine. Fluvoxamine The risk or severity of adverse effects can be increased when Cyamemazine is combined with Fluvoxamine. Fosphenytoin The serum concentration of Fosphenytoin can be increased when it is combined with Cyamemazine. Fospropofol The risk or severity of CNS depression can be increased when Fospropofol is combined with Cyamemazine. Frovatriptan The risk or severity of adverse effects can be increased when Frovatriptan is combined with Cyamemazine. Gabapentin The risk or severity of CNS depression can be increased when Gabapentin is combined with Cyamemazine. Gabapentin enacarbil The risk or severity of CNS depression can be increased when Gabapentin enacarbil is combined with Cyamemazine. Gallamine triethiodide The risk or severity of CNS depression can be increased when Gallamine triethiodide is combined with Cyamemazine. gamma-Hydroxybutyric acid The risk or severity of CNS depression can be increased when gamma-Hydroxybutyric acid is combined with Cyamemazine. Ganaxolone The risk or severity of sedation, somnolence, and CNS depression can be increased when Cyamemazine is combined with Ganaxolone. Gepirone The risk or severity of CNS depression can be increased when Cyamemazine is combined with Gepirone. Gliclazide The therapeutic efficacy of Gliclazide can be decreased when used in combination with Cyamemazine. Glimepiride The therapeutic efficacy of Glimepiride can be decreased when used in combination with Cyamemazine. Glipizide The therapeutic efficacy of Glipizide can be decreased when used in combination with Cyamemazine. Gliquidone The therapeutic efficacy of Gliquidone can be decreased when used in combination with Cyamemazine. Glutethimide The risk or severity of CNS depression can be increased when Glutethimide is combined with Cyamemazine. Glyburide The therapeutic efficacy of Glyburide can be decreased when used in combination with Cyamemazine. Granisetron The risk or severity of CNS depression can be increased when Granisetron is combined with Cyamemazine. Guanfacine The risk or severity of CNS depression can be increased when Guanfacine is combined with Cyamemazine. Halazepam The risk or severity of CNS depression can be increased when Halazepam is combined with Cyamemazine. Halofantrine The risk or severity of QTc prolongation can be increased when Halofantrine is combined with Cyamemazine. Haloperidol The risk or severity of CNS depression can be increased when Haloperidol is combined with Cyamemazine. Halothane The risk or severity of CNS depression can be increased when Halothane is combined with Cyamemazine. Hexafluronium The risk or severity of CNS depression can be increased when Hexafluronium is combined with Cyamemazine. Hydrocodone Cyamemazine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. Hydromorphone The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Hydromorphone. Hydrotalcite Hydrotalcite can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy. Hydroxychloroquine The risk or severity of QTc prolongation can be increased when Hydroxychloroquine is combined with Cyamemazine. Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine. Hyoscyamine Cyamemazine may increase the anticholinergic activities of Hyoscyamine. Iloperidone The risk or severity of CNS depression can be increased when Iloperidone is combined with Cyamemazine. Imipenem Imipenem may increase the neurotoxic activities of Cyamemazine. Imipramine The serum concentration of Imipramine can be increased when it is combined with Cyamemazine. Insulin aspart The therapeutic efficacy of Insulin aspart can be decreased when used in combination with Cyamemazine. Insulin beef The therapeutic efficacy of Insulin beef can be decreased when used in combination with Cyamemazine. Insulin degludec The therapeutic efficacy of Insulin degludec can be decreased when used in combination with Cyamemazine. Insulin detemir The therapeutic efficacy of Insulin detemir can be decreased when used in combination with Cyamemazine. Insulin glargine The therapeutic efficacy of Insulin glargine can be decreased when used in combination with Cyamemazine. Insulin glulisine The therapeutic efficacy of Insulin glulisine can be decreased when used in combination with Cyamemazine. Insulin human The therapeutic efficacy of Insulin human can be decreased when used in combination with Cyamemazine. Insulin lispro The therapeutic efficacy of Insulin lispro can be decreased when used in combination with Cyamemazine. Insulin pork The therapeutic efficacy of Insulin pork can be decreased when used in combination with Cyamemazine. Iofetamine I-123 Cyamemazine may decrease the stimulatory activities of Iofetamine I-123. Isocarboxazid The risk or severity of extrapyramidal symptoms can be increased when Isocarboxazid is combined with Cyamemazine. Isoflurane The risk or severity of CNS depression can be increased when Isoflurane is combined with Cyamemazine. Ketamine The risk or severity of CNS depression can be increased when Ketamine is combined with Cyamemazine. Ketazolam The risk or severity of CNS depression can be increased when Ketazolam is combined with Cyamemazine. Labetalol The serum concentration of Labetalol can be increased when it is combined with Cyamemazine. Lamotrigine The risk or severity of CNS depression can be increased when Lamotrigine is combined with Cyamemazine. Lasmiditan The risk or severity of adverse effects can be increased when Lasmiditan is combined with Cyamemazine. Lemborexant The risk or severity of CNS depression can be increased when Cyamemazine is combined with Lemborexant. Levacetylmethadol The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Levacetylmethadol. Levetiracetam The risk or severity of CNS depression can be increased when Levetiracetam is combined with Cyamemazine. Levobetaxolol The serum concentration of Levobetaxolol can be increased when it is combined with Cyamemazine. Levobupivacaine The risk or severity of CNS depression can be increased when Levobupivacaine is combined with Cyamemazine. Levocetirizine The risk or severity of CNS depression can be increased when Levocetirizine is combined with Cyamemazine. Levodopa The risk or severity of CNS depression can be increased when Levodopa is combined with Cyamemazine. Levomilnacipran The risk or severity of adverse effects can be increased when Levomilnacipran is combined with Cyamemazine. Levorphanol The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Levorphanol. Lidocaine The risk or severity of CNS depression can be increased when Lidocaine is combined with Cyamemazine. Lincomycin Lincomycin may increase the neurotoxic activities of Cyamemazine. Linezolid The risk or severity of extrapyramidal symptoms can be increased when Linezolid is combined with Cyamemazine. Lisdexamfetamine Cyamemazine may decrease the stimulatory activities of Lisdexamfetamine. Lisuride The risk or severity of CNS depression can be increased when Lisuride is combined with Cyamemazine. Lithium carbonate Lithium carbonate may increase the neurotoxic activities of Cyamemazine. Lithium citrate Lithium citrate may increase the neurotoxic activities of Cyamemazine. Lithium hydroxide Lithium hydroxide may increase the neurotoxic activities of Cyamemazine. Lofexidine The therapeutic efficacy of Cyamemazine can be increased when used in combination with Lofexidine. Lorazepam The risk or severity of CNS depression can be increased when Lorazepam is combined with Cyamemazine. Lorcaserin The risk or severity of adverse effects can be increased when Lorcaserin is combined with Cyamemazine. Lormetazepam The risk or severity of CNS depression can be increased when Cyamemazine is combined with Lormetazepam. Lorpiprazole The risk or severity of adverse effects can be increased when Lorpiprazole is combined with Cyamemazine. Loxapine The risk or severity of CNS depression can be increased when Loxapine is combined with Cyamemazine. Lumateperone The risk or severity of adverse effects can be increased when Lumateperone is combined with Cyamemazine. Lumefantrine The risk or severity of QTc prolongation can be increased when Lumefantrine is combined with Cyamemazine. Lurasidone The risk or severity of CNS depression can be increased when Lurasidone is combined with Cyamemazine. Magaldrate Magaldrate can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy. Magnesium carbonate Magnesium carbonate can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy. Magnesium hydroxide Magnesium hydroxide can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy. Magnesium oxide Magnesium oxide can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy. Magnesium silicate Magnesium silicate can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy. Magnesium sulfate The therapeutic efficacy of Cyamemazine can be increased when used in combination with Magnesium sulfate. Magnesium trisilicate Magnesium trisilicate can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy. Maprotiline The risk or severity of adverse effects can be increased when Maprotiline is combined with Cyamemazine. Mazindol The risk or severity of adverse effects can be increased when Mazindol is combined with Cyamemazine. Mebutamate The risk or severity of CNS depression can be increased when Mebutamate is combined with Cyamemazine. Meclizine The risk or severity of CNS depression can be increased when Meclizine is combined with Cyamemazine. Medifoxamine The risk or severity of CNS depression can be increased when Cyamemazine is combined with Medifoxamine. Mefloquine The risk or severity of QTc prolongation can be increased when Mefloquine is combined with Cyamemazine. Melatonin The risk or severity of CNS depression can be increased when Melatonin is combined with Cyamemazine. Meperidine The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Meperidine. Mephentermine Cyamemazine may decrease the stimulatory activities of Mephentermine. Mephenytoin The risk or severity of CNS depression can be increased when Mephenytoin is combined with Cyamemazine. Mepivacaine The risk or severity of CNS depression can be increased when Mepivacaine is combined with Cyamemazine. Meprobamate The risk or severity of CNS depression can be increased when Meprobamate is combined with Cyamemazine. Mepyramine The risk or severity of CNS depression can be increased when Mepyramine is combined with Cyamemazine. Mesoridazine The risk or severity of CNS depression can be increased when Mesoridazine is combined with Cyamemazine. Metamfetamine Cyamemazine may decrease the stimulatory activities of Metamfetamine. Metaxalone The risk or severity of CNS depression can be increased when Metaxalone is combined with Cyamemazine. Metergoline The risk or severity of CNS depression can be increased when Cyamemazine is combined with Metergoline. Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Cyamemazine. Methocarbamol The risk or severity of CNS depression can be increased when Methocarbamol is combined with Cyamemazine. Methohexital The risk or severity of CNS depression can be increased when Methohexital is combined with Cyamemazine. Methotrimeprazine Cyamemazine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine. Methoxyflurane The risk or severity of CNS depression can be increased when Methoxyflurane is combined with Cyamemazine. Methoxyphenamine Cyamemazine may decrease the stimulatory activities of Methoxyphenamine. Methsuximide The risk or severity of CNS depression can be increased when Methsuximide is combined with Cyamemazine. Methylene blue The risk or severity of extrapyramidal symptoms can be increased when Methylene blue is combined with Cyamemazine. Methylphenidate The risk or severity of adverse effects can be increased when Cyamemazine is combined with Methylphenidate. Methylphenobarbital The risk or severity of CNS depression can be increased when Methylphenobarbital is combined with Cyamemazine. Methyprylon The risk or severity of CNS depression can be increased when Methyprylon is combined with Cyamemazine. Methysergide The risk or severity of CNS depression can be increased when Methysergide is combined with Cyamemazine. Metoclopramide The risk or severity of adverse effects can be increased when Metoclopramide is combined with Cyamemazine. Metocurine The risk or severity of CNS depression can be increased when Metocurine is combined with Cyamemazine. Metocurine iodide The risk or severity of CNS depression can be increased when Metocurine iodide is combined with Cyamemazine. Metoprolol The serum concentration of Metoprolol can be increased when it is combined with Cyamemazine. Metyrosine The risk or severity of extrapyramidal symptoms and CNS depression can be increased when Metyrosine is combined with Cyamemazine. Mianserin The risk or severity of adverse effects can be increased when Mianserin is combined with Cyamemazine. Midazolam The risk or severity of sedation and CNS depression can be increased when Midazolam is combined with Cyamemazine. Milnacipran The risk or severity of adverse effects can be increased when Cyamemazine is combined with Milnacipran. Minaprine The risk or severity of extrapyramidal symptoms can be increased when Minaprine is combined with Cyamemazine. Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine. Mirtazapine Cyamemazine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine. Mivacurium The risk or severity of CNS depression can be increased when Mivacurium is combined with Cyamemazine. Moclobemide The risk or severity of extrapyramidal symptoms can be increased when Moclobemide is combined with Cyamemazine. Molindone The risk or severity of CNS depression can be increased when Molindone is combined with Cyamemazine. Moricizine The risk or severity of CNS depression can be increased when Moricizine is combined with Cyamemazine. Morphine The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Morphine. Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine. Nadolol The serum concentration of Nadolol can be increased when it is combined with Cyamemazine. Nalbuphine The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Nalbuphine. Naloxegol The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Naloxegol. Naltrexone The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Naltrexone. Naphazoline The risk or severity of CNS depression can be increased when Naphazoline is combined with Cyamemazine. Naratriptan The risk or severity of adverse effects can be increased when Naratriptan is combined with Cyamemazine. Naxitamab Cyamemazine may increase the neurotoxic activities of Naxitamab. Nebivolol The serum concentration of Nebivolol can be increased when it is combined with Cyamemazine. Nefazodone The risk or severity of adverse effects can be increased when Cyamemazine is combined with Nefazodone. Neomycin Neomycin may increase the neurotoxic activities of Cyamemazine. Nialamide The risk or severity of extrapyramidal symptoms can be increased when Nialamide is combined with Cyamemazine. Nitrazepam The risk or severity of CNS depression can be increased when Nitrazepam is combined with Cyamemazine. Nitrous oxide The risk or severity of CNS depression can be increased when Nitrous oxide is combined with Cyamemazine. Nomifensine The risk or severity of CNS depression can be increased when Nomifensine is combined with Cyamemazine. Normethadone The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Normethadone. Nortriptyline The serum concentration of Nortriptyline can be increased when it is combined with Cyamemazine. Olanzapine The risk or severity of CNS depression can be increased when Olanzapine is combined with Cyamemazine. Oliceridine The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Cyamemazine is combined with Oliceridine. Ondansetron The risk or severity of CNS depression can be increased when Ondansetron is combined with Cyamemazine. Opium The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Opium. Orphenadrine Cyamemazine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. Oxazepam The risk or severity of CNS depression can be increased when Oxazepam is combined with Cyamemazine. Oxcarbazepine The risk or severity of CNS depression can be increased when Oxcarbazepine is combined with Cyamemazine. Oxitriptan The risk or severity of CNS depression can be increased when Oxitriptan is combined with Cyamemazine. Oxprenolol The serum concentration of Oxprenolol can be increased when it is combined with Cyamemazine. Oxybuprocaine The risk or severity of CNS depression can be increased when Oxybuprocaine is combined with Cyamemazine. Oxycodone The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Oxycodone. Oxymorphone The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Oxymorphone. Paclitaxel Paclitaxel may increase the neurotoxic activities of Cyamemazine. Padeliporfin Cyamemazine may increase the photosensitizing activities of Padeliporfin. Paliperidone The risk or severity of CNS depression can be increased when Paliperidone is combined with Cyamemazine. Palonosetron The risk or severity of CNS depression can be increased when Palonosetron is combined with Cyamemazine. Pancuronium The risk or severity of CNS depression can be increased when Pancuronium is combined with Cyamemazine. Paraldehyde Cyamemazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde. Paramethadione The risk or severity of CNS depression can be increased when Paramethadione is combined with Cyamemazine. Pargyline The risk or severity of extrapyramidal symptoms can be increased when Pargyline is combined with Cyamemazine. Paroxetine The risk or severity of adverse effects can be increased when Cyamemazine is combined with Paroxetine. Penbutolol The serum concentration of Penbutolol can be increased when it is combined with Cyamemazine. Pentazocine The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Pentazocine. Pentobarbital The risk or severity of CNS depression can be increased when Pentobarbital is combined with Cyamemazine. Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine. Perazine The risk or severity of CNS depression can be increased when Cyamemazine is combined with Perazine. Pergolide The risk or severity of CNS depression can be increased when Pergolide is combined with Cyamemazine. Periciazine The risk or severity of CNS depression can be increased when Periciazine is combined with Cyamemazine. Perphenazine The risk or severity of CNS depression can be increased when Perphenazine is combined with Cyamemazine. Phenacemide The risk or severity of CNS depression can be increased when Phenacemide is combined with Cyamemazine. Phendimetrazine Cyamemazine may decrease the stimulatory activities of Phendimetrazine. Phenelzine The risk or severity of extrapyramidal symptoms can be increased when Phenelzine is combined with Cyamemazine. Phenobarbital The risk or severity of CNS depression can be increased when Phenobarbital is combined with Cyamemazine. Phensuximide The risk or severity of CNS depression can be increased when Phensuximide is combined with Cyamemazine. Phentermine Cyamemazine may decrease the stimulatory activities of Phentermine. Phenytoin The serum concentration of Phenytoin can be increased when it is combined with Cyamemazine. Pimavanserin Pimavanserin may increase the neurotoxic activities of Cyamemazine. Pimozide The risk or severity of CNS depression can be increased when Pimozide is combined with Cyamemazine. Pindolol The serum concentration of Pindolol can be increased when it is combined with Cyamemazine. Pipecuronium The risk or severity of CNS depression can be increased when Pipecuronium is combined with Cyamemazine. Piperaquine The risk or severity of QTc prolongation can be increased when Piperaquine is combined with Cyamemazine. Pipotiazine The risk or severity of CNS depression can be increased when Pipotiazine is combined with Cyamemazine. Piritramide The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Piritramide. Pizotifen The risk or severity of CNS depression can be increased when Pizotifen is combined with Cyamemazine. Polymyxin B Cyamemazine may increase the neurotoxic activities of Polymyxin B. Pomalidomide The risk or severity of CNS depression can be increased when Pomalidomide is combined with Cyamemazine. Porfimer sodium Cyamemazine may increase the photosensitizing activities of Porfimer sodium. Practolol The serum concentration of Practolol can be increased when it is combined with Cyamemazine. Pramipexole Cyamemazine may increase the sedative activities of Pramipexole. Pramocaine The risk or severity of CNS depression can be increased when Cyamemazine is combined with Pramocaine. Prazepam The risk or severity of CNS depression can be increased when Prazepam is combined with Cyamemazine. Pregabalin The therapeutic efficacy of Cyamemazine can be increased when used in combination with Pregabalin. Prilocaine The risk or severity of CNS depression can be increased when Prilocaine is combined with Cyamemazine. Primaquine The risk or severity of QTc prolongation can be increased when Primaquine is combined with Cyamemazine. Primidone The risk or severity of CNS depression can be increased when Primidone is combined with Cyamemazine. Procaine The risk or severity of extrapyramidal symptoms can be increased when Procaine is combined with Cyamemazine. Procarbazine The risk or severity of extrapyramidal symptoms can be increased when Procarbazine is combined with Cyamemazine. Prochlorperazine The risk or severity of CNS depression can be increased when Prochlorperazine is combined with Cyamemazine. Proguanil The risk or severity of QTc prolongation can be increased when Proguanil is combined with Cyamemazine. Promazine The risk or severity of CNS depression can be increased when Promazine is combined with Cyamemazine. Promethazine The risk or severity of adverse effects can be increased when Promethazine is combined with Cyamemazine. Propafenone The serum concentration of Propafenone can be increased when it is combined with Cyamemazine. Propiomazine The risk or severity of CNS depression can be increased when Propiomazine is combined with Cyamemazine. Propofol The risk or severity of CNS depression can be increased when Propofol is combined with Cyamemazine. Propranolol The serum concentration of Propranolol can be increased when it is combined with Cyamemazine. Protriptyline The serum concentration of Protriptyline can be increased when it is combined with Cyamemazine. Proxibarbal The risk or severity of CNS depression can be increased when Cyamemazine is combined with Proxibarbal. Pseudoephedrine Cyamemazine may decrease the stimulatory activities of Pseudoephedrine. Pyrantel The risk or severity of CNS depression can be increased when Cyamemazine is combined with Pyrantel. Pyrimethamine The risk or severity of QTc prolongation can be increased when Pyrimethamine is combined with Cyamemazine. Quazepam The risk or severity of CNS depression can be increased when Quazepam is combined with Cyamemazine. Quetiapine The risk or severity of CNS depression can be increased when Quetiapine is combined with Cyamemazine. Quinagolide The therapeutic efficacy of Quinagolide can be decreased when used in combination with Cyamemazine. Quinidine The risk or severity of QTc prolongation can be increased when Quinidine is combined with Cyamemazine. Quinine The risk or severity of QTc prolongation can be increased when Quinine is combined with Cyamemazine. Quinupramine The serum concentration of Quinupramine can be increased when it is combined with Cyamemazine. Ramelteon The risk or severity of CNS depression can be increased when Ramelteon is combined with Cyamemazine. Rapacuronium The risk or severity of CNS depression can be increased when Rapacuronium is combined with Cyamemazine. Rasagiline The risk or severity of extrapyramidal symptoms can be increased when Rasagiline is combined with Cyamemazine. Reboxetine The risk or severity of CNS depression can be increased when Reboxetine is combined with Cyamemazine. Remifentanil The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Remifentanil. Remimazolam The risk or severity of sedation can be increased when Cyamemazine is combined with Remimazolam. Remoxipride The risk or severity of CNS depression can be increased when Remoxipride is combined with Cyamemazine. Reserpine The risk or severity of CNS depression can be increased when Reserpine is combined with Cyamemazine. Riluzole The risk or severity of CNS depression can be increased when Riluzole is combined with Cyamemazine. Rimonabant The risk or severity of adverse effects can be increased when Rimonabant is combined with Cyamemazine. Risperidone The risk or severity of CNS depression can be increased when Risperidone is combined with Cyamemazine. Rizatriptan The risk or severity of adverse effects can be increased when Rizatriptan is combined with Cyamemazine. Rocuronium The risk or severity of CNS depression can be increased when Rocuronium is combined with Cyamemazine. Ropeginterferon alfa-2b The risk or severity of neuropsychiatric effects can be increased when Ropeginterferon alfa-2b is combined with Cyamemazine. Ropinirole Cyamemazine may increase the sedative activities of Ropinirole. Ropivacaine The risk or severity of CNS depression can be increased when Ropivacaine is combined with Cyamemazine. Rotigotine Cyamemazine may increase the sedative activities of Rotigotine. Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Cyamemazine. Safinamide The risk or severity of extrapyramidal symptoms can be increased when Safinamide is combined with Cyamemazine. Samidorphan The risk or severity of CNS depression can be increased when Cyamemazine is combined with Samidorphan. Scopolamine The risk or severity of CNS depression can be increased when Scopolamine is combined with Cyamemazine. Secobarbital The risk or severity of CNS depression can be increased when Secobarbital is combined with Cyamemazine. Selegiline The risk or severity of extrapyramidal symptoms can be increased when Selegiline is combined with Cyamemazine. Sertindole The risk or severity of CNS depression can be increased when Sertindole is combined with Cyamemazine. Sertraline The risk or severity of adverse effects can be increased when Cyamemazine is combined with Sertraline. Sevoflurane The risk or severity of CNS depression can be increased when Sevoflurane is combined with Cyamemazine. Sibutramine The risk or severity of adverse effects can be increased when Cyamemazine is combined with Sibutramine. Sodium bicarbonate Sodium bicarbonate can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy. Sodium citrate Cyamemazine may increase the neurotoxic activities of Sodium citrate. Sodium oxybate Cyamemazine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate. Solriamfetol The risk or severity of CNS depression can be increased when Cyamemazine is combined with Solriamfetol. Sotalol The serum concentration of Sotalol can be increased when it is combined with Cyamemazine. St. John's Wort The risk or severity of CNS depression can be increased when St. John's Wort is combined with Cyamemazine. Stavudine Stavudine may increase the neurotoxic activities of Cyamemazine. Stiripentol The risk or severity of CNS depression can be increased when Cyamemazine is combined with Stiripentol. Succinylcholine The risk or severity of CNS depression can be increased when Succinylcholine is combined with Cyamemazine. Sufentanil The risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Sufentanil. Sulfadoxine The risk or severity of QTc prolongation can be increased when Sulfadoxine is combined with Cyamemazine. Sulpiride Cyamemazine may increase the antipsychotic activities of Sulpiride. Sulthiame The risk or severity of CNS depression can be increased when Sulthiame is combined with Cyamemazine. Sultopride The risk or severity of CNS depression can be increased when Cyamemazine is combined with Sultopride. Sumatriptan The risk or severity of adverse effects can be increased when Sumatriptan is combined with Cyamemazine. Suvorexant Cyamemazine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. Tafenoquine The risk or severity of QTc prolongation can be increased when Tafenoquine is combined with Cyamemazine. Talbutal The risk or severity of CNS depression can be increased when Talbutal is combined with Cyamemazine. Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine. Tasimelteon The risk or severity of CNS depression can be increased when Cyamemazine is combined with Tasimelteon. Temazepam The risk or severity of CNS depression can be increased when Temazepam is combined with Cyamemazine. Teniposide Teniposide may increase the neurotoxic activities of Cyamemazine. Tetrabenazine The risk or severity of adverse effects can be increased when Cyamemazine is combined with Tetrabenazine. Tetracaine The risk or severity of CNS depression can be increased when Cyamemazine is combined with Tetracaine. Thalidomide Cyamemazine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. Thiamylal The risk or severity of CNS depression can be increased when Thiamylal is combined with Cyamemazine. Thiethylperazine The risk or severity of CNS depression can be increased when Thiethylperazine is combined with Cyamemazine. Thiopental The risk or severity of adverse effects can be increased when Cyamemazine is combined with Thiopental. Thioridazine The risk or severity of CNS depression can be increased when Thioridazine is combined with Cyamemazine. Thiothixene The risk or severity of CNS depression can be increased when Thiothixene is combined with Cyamemazine. Tiagabine The risk or severity of CNS depression can be increased when Tiagabine is combined with Cyamemazine. Timolol The serum concentration of Timolol can be increased when it is combined with Cyamemazine. Tizanidine The risk or severity of CNS depression can be increased when Tizanidine is combined with Cyamemazine. Tolazamide The therapeutic efficacy of Tolazamide can be decreased when used in combination with Cyamemazine. Tolbutamide The therapeutic efficacy of Tolbutamide can be decreased when used in combination with Cyamemazine. Tolcapone The risk or severity of CNS depression can be increased when Tolcapone is combined with Cyamemazine. Topiramate The risk or severity of CNS depression can be increased when Topiramate is combined with Cyamemazine. Tramadol The risk or severity of CNS depression can be increased when Cyamemazine is combined with Tramadol. Tranylcypromine The risk or severity of extrapyramidal symptoms can be increased when Tranylcypromine is combined with Cyamemazine. Trazodone The risk or severity of adverse effects can be increased when Cyamemazine is combined with Trazodone. Tretinoin The risk or severity of adverse effects can be increased when Tretinoin is combined with Cyamemazine. Triazolam The risk or severity of CNS depression can be increased when Triazolam is combined with Cyamemazine. Trichloroethylene The risk or severity of CNS depression can be increased when Cyamemazine is combined with Trichloroethylene. Triclofos The risk or severity of CNS depression can be increased when Triclofos is combined with Cyamemazine. Trifluoperazine The risk or severity of CNS depression can be increased when Trifluoperazine is combined with Cyamemazine. Triflupromazine The risk or severity of CNS depression can be increased when Triflupromazine is combined with Cyamemazine. Trimethadione The risk or severity of CNS depression can be increased when Trimethadione is combined with Cyamemazine. Trimethobenzamide The risk or severity of CNS depression can be increased when Trimethobenzamide is combined with Cyamemazine. Trimipramine The serum concentration of Trimipramine can be increased when it is combined with Cyamemazine. Triprolidine The risk or severity of CNS depression can be increased when Triprolidine is combined with Cyamemazine. Tropisetron The risk or severity of CNS depression can be increased when Cyamemazine is combined with Tropisetron. Tryptophan The risk or severity of CNS depression can be increased when Tryptophan is combined with Cyamemazine. Tubocurarine The risk or severity of CNS depression can be increased when Tubocurarine is combined with Cyamemazine. Urethane The risk or severity of CNS depression can be increased when Urethane is combined with Cyamemazine. Valproate bismuth Cyamemazine may increase the neurotoxic activities of Valproate bismuth. Valproic acid The risk or severity of CNS depression can be increased when Valproic acid is combined with Cyamemazine. Vecuronium The risk or severity of CNS depression can be increased when Vecuronium is combined with Cyamemazine. Venlafaxine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Cyamemazine. Verteporfin Cyamemazine may increase the photosensitizing activities of Verteporfin. Vigabatrin The risk or severity of CNS depression can be increased when Vigabatrin is combined with Cyamemazine. Vilazodone The risk or severity of adverse effects can be increased when Vilazodone is combined with Cyamemazine. Viloxazine The risk or severity of CNS depression can be increased when Cyamemazine is combined with Viloxazine. Vincristine Vincristine may increase the neurotoxic activities of Cyamemazine. Vinorelbine Vinorelbine may increase the neurotoxic activities of Cyamemazine. Viomycin Viomycin may increase the neurotoxic activities of Cyamemazine. Vortioxetine The risk or severity of adverse effects can be increased when Vortioxetine is combined with Cyamemazine. Yohimbine The therapeutic efficacy of Cyamemazine can be increased when used in combination with Yohimbine. Zaleplon The risk or severity of CNS depression can be increased when Zaleplon is combined with Cyamemazine. Ziconotide The risk or severity of CNS depression can be increased when Cyamemazine is combined with Ziconotide. Zimelidine The risk or severity of adverse effects can be increased when Cyamemazine is combined with Zimelidine. Ziprasidone The risk or severity of adverse effects can be increased when Cyamemazine is combined with Ziprasidone. Zolmitriptan The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Cyamemazine. Zolpidem Cyamemazine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. Zonisamide The risk or severity of CNS depression can be increased when Zonisamide is combined with Cyamemazine. Zopiclone The risk or severity of adverse effects can be increased when Cyamemazine is combined with Zopiclone. Zotepine The risk or severity of CNS depression can be increased when Cyamemazine is combined with Zotepine. Zuclopenthixol The risk or severity of CNS depression can be increased when Zuclopenthixol is combined with Cyamemazine. Zuranolone The risk or severity of CNS depression can be increased when Zuranolone is combined with Cyamemazine. - Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- International/Other Brands
- Tercian (Sanofi-Aventis)
Categories
- ATC Codes
- N05AA06 — Cyamemazine
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as phenothiazines. These are polycyclic aromatic compounds containing a phenothiazine moiety, which is a linear tricyclic system that consists of a two benzene rings joined by a para-thiazine ring.
- Kingdom
- Organic compounds
- Super Class
- Organoheterocyclic compounds
- Class
- Benzothiazines
- Sub Class
- Phenothiazines
- Direct Parent
- Phenothiazines
- Alternative Parents
- Alkyldiarylamines / Diarylthioethers / Benzenoids / 1,4-thiazines / Trialkylamines / Nitriles / Azacyclic compounds / Organopnictogen compounds / Hydrocarbon derivatives
- Substituents
- Alkyldiarylamine / Amine / Aromatic heteropolycyclic compound / Aryl thioether / Azacycle / Benzenoid / Carbonitrile / Diarylthioether / Hydrocarbon derivative / Nitrile
- Molecular Framework
- Aromatic heteropolycyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- A2JGV5CNU4
- CAS number
- 3546-03-0
- InChI Key
- SLFGIOIONGJGRT-UHFFFAOYSA-N
- InChI
- InChI=1S/C19H21N3S/c1-14(12-21(2)3)13-22-16-6-4-5-7-18(16)23-19-9-8-15(11-20)10-17(19)22/h4-10,14H,12-13H2,1-3H3
- IUPAC Name
- 10-[3-(dimethylamino)-2-methylpropyl]-10H-phenothiazine-2-carbonitrile
- SMILES
- CC(CN(C)C)CN1C2=CC=CC=C2SC2=C1C=C(C=C2)C#N
References
- Synthesis Reference
U.S. Patent 2,877,224.
- General References
- Not Available
- External Links
- KEGG Drug
- D07307
- PubChem Compound
- 62865
- PubChem Substance
- 310264961
- ChemSpider
- 56597
- BindingDB
- 86057
- 21877
- ChEBI
- 135379
- ChEMBL
- CHEMBL2104153
- Drugs.com
- Drugs.com Drug Page
- Wikipedia
- Cyamemazine
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Solid
- Experimental Properties
Property Value Source melting point (°C) 204-205 U.S. Patent 2,877,224. - Predicted Properties
Property Value Source Water Solubility 0.029 mg/mL ALOGPS logP 4.28 ALOGPS logP 4.27 Chemaxon logS -4 ALOGPS pKa (Strongest Basic) 9.42 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 30.27 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 99.09 m3·mol-1 Chemaxon Polarizability 36.48 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted GC-MS Spectrum - GC-MS Predicted GC-MS splash10-052r-4091000000-8fd4f49543d5acc4171d Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS splash10-0fk9-0809000000-e9a47ba9e9b612c317f0 Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS splash10-00di-0029000000-688c415606fcea11bb52 Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS splash10-00di-0029000000-bace050610190a6af660 Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS splash10-0q29-9355000000-66285b2e31caa1879c98 Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS splash10-00dr-0190000000-0d53fef3947fb7c85f1c Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS splash10-056r-5290000000-0730f877de6790187b95 Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 167.3835 predictedDeepCCS 1.0 (2019) [M+H]+ 169.7415 predictedDeepCCS 1.0 (2019) [M+Na]+ 176.07875 predictedDeepCCS 1.0 (2019)
Drug created at June 17, 2014 16:28 / Updated at February 21, 2021 18:52