Cyamemazine

Identification

Generic Name
Cyamemazine
DrugBank Accession Number
DB09000
Background

Cyamemazine (Tercian), also known as cyamepromazine, is a typical antipsychotic drug of the phenothiazine class used primarily in the treatment of schizophrenia and psychosis-associated anxiety. Cyamemazine actually behaves like an atypical antipsychotic, due to its potent anxiolytic effects (5-HT2C) and lack of extrapyramidal side effects (5-HT2A).

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 323.455
Monoisotopic: 323.145618377
Chemical Formula
C19H21N3S
Synonyms
  • Cyamemazine

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
1,2-BenzodiazepineThe risk or severity of CNS depression can be increased when Cyamemazine is combined with 1,2-Benzodiazepine.
AcebutololThe serum concentration of Acebutolol can be increased when it is combined with Cyamemazine.
AcetazolamideThe risk or severity of CNS depression can be increased when Acetazolamide is combined with Cyamemazine.
AcetohexamideThe therapeutic efficacy of Acetohexamide can be decreased when used in combination with Cyamemazine.
AcetophenazineThe risk or severity of CNS depression can be increased when Acetophenazine is combined with Cyamemazine.
AgomelatineThe risk or severity of CNS depression can be increased when Agomelatine is combined with Cyamemazine.
AlfentanilThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Alfentanil.
AlimemazineThe risk or severity of CNS depression can be increased when Alimemazine is combined with Cyamemazine.
AlmasilateAlmasilate can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
AlmotriptanThe risk or severity of adverse effects can be increased when Almotriptan is combined with Cyamemazine.
AlosetronThe risk or severity of CNS depression can be increased when Alosetron is combined with Cyamemazine.
AlprazolamThe risk or severity of CNS depression can be increased when Alprazolam is combined with Cyamemazine.
AluminiumAluminium can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Aluminium phosphateAluminium phosphate can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Aluminum hydroxideAluminum hydroxide can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
AlverineThe risk or severity of CNS depression can be increased when Alverine is combined with Cyamemazine.
AmisulprideCyamemazine may increase the antipsychotic activities of Amisulpride.
AmitriptylineThe serum concentration of Amitriptyline can be increased when it is combined with Cyamemazine.
AmitriptylinoxideThe serum concentration of Amitriptylinoxide can be increased when it is combined with Cyamemazine.
AmobarbitalThe risk or severity of CNS depression can be increased when Amobarbital is combined with Cyamemazine.
AmodiaquineThe risk or severity of QTc prolongation can be increased when Amodiaquine is combined with Cyamemazine.
AmoxapineThe serum concentration of Amoxapine can be increased when it is combined with Cyamemazine.
AmphetamineCyamemazine may decrease the stimulatory activities of Amphetamine.
ApomorphineThe risk or severity of CNS depression can be increased when Apomorphine is combined with Cyamemazine.
ApronalideThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Apronalide.
AripiprazoleThe risk or severity of CNS depression can be increased when Aripiprazole is combined with Cyamemazine.
Aripiprazole lauroxilThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Aripiprazole lauroxil.
ArtemetherThe risk or severity of QTc prolongation can be increased when Artemether is combined with Cyamemazine.
ArtemotilThe risk or severity of QTc prolongation can be increased when Artemotil is combined with Cyamemazine.
ArtenimolThe risk or severity of QTc prolongation can be increased when Artenimol is combined with Cyamemazine.
ArtesunateThe risk or severity of QTc prolongation can be increased when Artesunate is combined with Cyamemazine.
ArticaineThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Articaine.
AsenapineThe risk or severity of CNS depression can be increased when Asenapine is combined with Cyamemazine.
AtenololThe serum concentration of Atenolol can be increased when it is combined with Cyamemazine.
AtovaquoneThe risk or severity of QTc prolongation can be increased when Atovaquone is combined with Cyamemazine.
AtracuriumThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Atracurium.
Atracurium besylateThe risk or severity of CNS depression can be increased when Atracurium besylate is combined with Cyamemazine.
AzelastineCyamemazine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
BaclofenBaclofen may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine.
BenperidolThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Benperidol.
BenzhydrocodoneThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Benzhydrocodone.
BenzocaineThe risk or severity of CNS depression can be increased when Benzocaine is combined with Cyamemazine.
BenzphetamineCyamemazine may decrease the stimulatory activities of Benzphetamine.
Benzyl alcoholThe risk or severity of CNS depression can be increased when Benzyl alcohol is combined with Cyamemazine.
BetaxololThe serum concentration of Betaxolol can be increased when it is combined with Cyamemazine.
Bismuth subcitrate potassiumCyamemazine may increase the neurotoxic activities of Bismuth subcitrate potassium.
Bismuth subgallateCyamemazine may increase the neurotoxic activities of Bismuth subgallate.
Bismuth subnitrateBismuth subnitrate can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
BisoprololThe serum concentration of Bisoprolol can be increased when it is combined with Cyamemazine.
Botulinum toxin type AThe risk or severity of CNS depression can be increased when Botulinum toxin type A is combined with Cyamemazine.
Botulinum toxin type BThe risk or severity of CNS depression can be increased when Botulinum toxin type B is combined with Cyamemazine.
BrexanoloneThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Brexanolone.
BrexpiprazoleThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Brexpiprazole.
BrimonidineBrimonidine may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine.
BrivaracetamThe risk or severity of CNS depression can be increased when Brivaracetam is combined with Cyamemazine.
BromazepamThe risk or severity of CNS depression can be increased when Bromazepam is combined with Cyamemazine.
BromocriptineThe risk or severity of adverse effects can be increased when Bromocriptine is combined with Cyamemazine.
BromperidolThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Bromperidol.
BrompheniramineThe risk or severity of CNS depression can be increased when Brompheniramine is combined with Cyamemazine.
BupivacaineThe risk or severity of CNS depression can be increased when Bupivacaine is combined with Cyamemazine.
BuprenorphineCyamemazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
BupropionThe risk or severity of CNS depression can be increased when Bupropion is combined with Cyamemazine.
BuspironeThe risk or severity of CNS depression can be increased when Buspirone is combined with Cyamemazine.
ButabarbitalThe risk or severity of CNS depression can be increased when Butabarbital is combined with Cyamemazine.
ButalbitalThe risk or severity of CNS depression can be increased when Butalbital is combined with Cyamemazine.
ButaperazineThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Butaperazine.
ButobarbitalThe risk or severity of CNS depression can be increased when Butobarbital is combined with Cyamemazine.
ButorphanolThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Butorphanol.
ButriptylineThe serum concentration of Butriptyline can be increased when it is combined with Cyamemazine.
CabergolineThe risk or severity of adverse effects can be increased when Cabergoline is combined with Cyamemazine.
Calcium carbonateCalcium carbonate can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
CannabidiolThe risk or severity of adverse effects can be increased when Cannabidiol is combined with Cyamemazine.
CarbamazepineThe risk or severity of CNS depression can be increased when Carbamazepine is combined with Cyamemazine.
CarbinoxamineThe risk or severity of CNS depression can be increased when Carbinoxamine is combined with Cyamemazine.
CariprazineThe risk or severity of CNS depression can be increased when Cariprazine is combined with Cyamemazine.
CarisoprodolThe risk or severity of adverse effects can be increased when Carisoprodol is combined with Cyamemazine.
CarvedilolThe serum concentration of Carvedilol can be increased when it is combined with Cyamemazine.
CeliprololThe serum concentration of Celiprolol can be increased when it is combined with Cyamemazine.
CetirizineThe risk or severity of CNS depression can be increased when Cetirizine is combined with Cyamemazine.
Chloral hydrateThe risk or severity of CNS depression can be increased when Chloral hydrate is combined with Cyamemazine.
ChlordiazepoxideThe risk or severity of CNS depression can be increased when Chlordiazepoxide is combined with Cyamemazine.
ChlormezanoneThe risk or severity of CNS depression can be increased when Chlormezanone is combined with Cyamemazine.
ChloroprocaineThe risk or severity of CNS depression can be increased when Chloroprocaine is combined with Cyamemazine.
ChloroquineThe risk or severity of QTc prolongation can be increased when Chloroquine is combined with Cyamemazine.
ChlorpheniramineThe risk or severity of adverse effects can be increased when Chlorpheniramine is combined with Cyamemazine.
ChlorpromazineThe risk or severity of CNS depression can be increased when Chlorpromazine is combined with Cyamemazine.
ChlorpropamideThe therapeutic efficacy of Chlorpropamide can be decreased when used in combination with Cyamemazine.
ChlorprothixeneThe risk or severity of CNS depression can be increased when Chlorprothixene is combined with Cyamemazine.
ChlorzoxazoneThe risk or severity of CNS depression can be increased when Chlorzoxazone is combined with Cyamemazine.
CinchocaineThe risk or severity of CNS depression can be increased when Cinchocaine is combined with Cyamemazine.
CisaprideThe risk or severity of CNS depression can be increased when Cisapride is combined with Cyamemazine.
CisatracuriumThe risk or severity of CNS depression can be increased when Cisatracurium is combined with Cyamemazine.
CitalopramThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Citalopram.
ClemastineThe risk or severity of CNS depression can be increased when Clemastine is combined with Cyamemazine.
ClidiniumThe risk or severity of CNS depression can be increased when Clidinium is combined with Cyamemazine.
ClindamycinClindamycin may increase the neurotoxic activities of Cyamemazine.
ClobazamThe risk or severity of sedation, somnolence, and CNS depression can be increased when Clobazam is combined with Cyamemazine.
ClomipramineThe serum concentration of desmethylclomipramine, an active metabolite of Clomipramine, can be increased when used in combination with Cyamemazine.
ClonazepamThe risk or severity of CNS depression can be increased when Clonazepam is combined with Cyamemazine.
ClonidineThe risk or severity of sedation can be increased when Clonidine is combined with Cyamemazine.
Clorazepic acidThe risk or severity of CNS depression can be increased when Clorazepic acid is combined with Cyamemazine.
ClothiapineThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Clothiapine.
ClotiazepamThe risk or severity of CNS depression can be increased when Clotiazepam is combined with Cyamemazine.
ClozapineThe risk or severity of CNS depression can be increased when Clozapine is combined with Cyamemazine.
CodeineThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Codeine.
CyclizineThe risk or severity of CNS depression can be increased when Cyclizine is combined with Cyamemazine.
CyclobenzaprineThe risk or severity of CNS depression can be increased when Cyclobenzaprine is combined with Cyamemazine.
CycloguanilThe risk or severity of QTc prolongation can be increased when Cycloguanil is combined with Cyamemazine.
CyclophosphamideCyclophosphamide may increase the neurotoxic activities of Cyamemazine.
CycloserineCycloserine may increase the neurotoxic activities of Cyamemazine.
CyclosporineCyclosporine may increase the neurotoxic activities of Cyamemazine.
CyproheptadineThe risk or severity of CNS depression can be increased when Cyproheptadine is combined with Cyamemazine.
DantroleneThe risk or severity of CNS depression can be increased when Dantrolene is combined with Cyamemazine.
DapsoneThe risk or severity of QTc prolongation can be increased when Dapsone is combined with Cyamemazine.
DaridorexantThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Daridorexant.
DecamethoniumThe risk or severity of CNS depression can be increased when Decamethonium is combined with Cyamemazine.
DesfluraneThe risk or severity of CNS depression can be increased when Desflurane is combined with Cyamemazine.
DesipramineThe serum concentration of Desipramine can be increased when it is combined with Cyamemazine.
DesloratadineThe risk or severity of CNS depression can be increased when Desloratadine is combined with Cyamemazine.
DesvenlafaxineThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Desvenlafaxine.
DeutetrabenazineThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Deutetrabenazine.
DexbrompheniramineThe risk or severity of CNS depression can be increased when Dexbrompheniramine is combined with Cyamemazine.
DexmedetomidineThe risk or severity of CNS depression can be increased when Dexmedetomidine is combined with Cyamemazine.
DexmethylphenidateThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Dexmethylphenidate.
DextroamphetamineCyamemazine may decrease the stimulatory activities of Dextroamphetamine.
DextromethorphanThe risk or severity of adverse effects can be increased when Dextromethorphan is combined with Cyamemazine.
DextropropoxypheneThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Dextropropoxyphene.
DezocineThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Dezocine.
DiamorphineThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Diamorphine.
DiazepamThe risk or severity of CNS depression can be increased when Diazepam is combined with Cyamemazine.
DibenzepinThe serum concentration of Dibenzepin can be increased when it is combined with Cyamemazine.
DichloralphenazoneThe risk or severity of CNS depression can be increased when Dichloralphenazone is combined with Cyamemazine.
DidanosineDidanosine may increase the neurotoxic activities of Cyamemazine.
DiethylpropionCyamemazine may decrease the stimulatory activities of Diethylpropion.
DifenoxinThe risk or severity of CNS depression can be increased when Difenoxin is combined with Cyamemazine.
DihydrocodeineThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Dihydrocodeine.
DihydroergotamineThe risk or severity of adverse effects can be increased when Dihydroergotamine is combined with Cyamemazine.
DimenhydrinateThe risk or severity of CNS depression can be increased when Dimenhydrinate is combined with Cyamemazine.
DiphenhydramineThe risk or severity of CNS depression can be increased when Diphenhydramine is combined with Cyamemazine.
DiphenoxylateThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Diphenoxylate.
DolasetronThe risk or severity of CNS depression can be increased when Dolasetron is combined with Cyamemazine.
DonepezilThe risk or severity of CNS depression can be increased when Donepezil is combined with Cyamemazine.
DosulepinThe serum concentration of Dosulepin can be increased when it is combined with Cyamemazine.
DoxacuriumThe risk or severity of CNS depression can be increased when Doxacurium is combined with Cyamemazine.
DoxepinThe serum concentration of Doxepin can be increased when it is combined with Cyamemazine.
DoxylamineDoxylamine may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine.
DronabinolDronabinol may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine.
DroperidolDroperidol may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine.
DuloxetineThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Duloxetine.
DyclonineThe risk or severity of CNS depression can be increased when Dyclonine is combined with Cyamemazine.
EfavirenzThe risk or severity of CNS depression can be increased when Efavirenz is combined with Cyamemazine.
EletriptanThe risk or severity of adverse effects can be increased when Eletriptan is combined with Cyamemazine.
EluxadolineThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Eluxadoline.
EnfluraneThe risk or severity of CNS depression can be increased when Enflurane is combined with Cyamemazine.
EntacaponeThe risk or severity of CNS depression can be increased when Entacapone is combined with Cyamemazine.
EpinastineThe risk or severity of CNS depression can be increased when Epinastine is combined with Cyamemazine.
Ergoloid mesylateThe risk or severity of adverse effects can be increased when Ergoloid mesylate is combined with Cyamemazine.
ErgometrineThe risk or severity of adverse effects can be increased when Ergometrine is combined with Cyamemazine.
ErgotamineThe risk or severity of adverse effects can be increased when Ergotamine is combined with Cyamemazine.
EscitalopramThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Escitalopram.
EsketamineThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Esketamine.
EslicarbazepineThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Eslicarbazepine.
Eslicarbazepine acetateThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Eslicarbazepine acetate.
EsmololThe serum concentration of Esmolol can be increased when it is combined with Cyamemazine.
EstazolamThe risk or severity of CNS depression can be increased when Estazolam is combined with Cyamemazine.
EszopicloneThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Eszopiclone.
EthanolCyamemazine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
EthchlorvynolThe risk or severity of CNS depression can be increased when Ethchlorvynol is combined with Cyamemazine.
EthosuximideThe risk or severity of CNS depression can be increased when Ethosuximide is combined with Cyamemazine.
EthotoinThe risk or severity of CNS depression can be increased when Ethotoin is combined with Cyamemazine.
EtomidateThe risk or severity of CNS depression can be increased when Etomidate is combined with Cyamemazine.
EzogabineThe risk or severity of CNS depression can be increased when Ezogabine is combined with Cyamemazine.
FelbamateThe risk or severity of CNS depression can be increased when Felbamate is combined with Cyamemazine.
FenfluramineThe risk or severity of CNS depression can be increased when Fenfluramine is combined with Cyamemazine.
FentanylThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Fentanyl.
FlibanserinThe risk or severity of CNS depression can be increased when Flibanserin is combined with Cyamemazine.
FlunarizineThe risk or severity of CNS depression can be increased when Flunarizine is combined with Cyamemazine.
FlunitrazepamThe risk or severity of CNS depression can be increased when Flunitrazepam is combined with Cyamemazine.
FluoxetineCyamemazine may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
FlupentixolThe risk or severity of CNS depression can be increased when Flupentixol is combined with Cyamemazine.
FluphenazineThe risk or severity of CNS depression can be increased when Fluphenazine is combined with Cyamemazine.
FlurazepamThe risk or severity of CNS depression can be increased when Flurazepam is combined with Cyamemazine.
FluspirileneThe risk or severity of CNS depression can be increased when Fluspirilene is combined with Cyamemazine.
Fluticasone propionateThe risk or severity of CNS depression can be increased when Fluticasone propionate is combined with Cyamemazine.
FluvoxamineThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Fluvoxamine.
FosphenytoinThe serum concentration of Fosphenytoin can be increased when it is combined with Cyamemazine.
FospropofolThe risk or severity of CNS depression can be increased when Fospropofol is combined with Cyamemazine.
FrovatriptanThe risk or severity of adverse effects can be increased when Frovatriptan is combined with Cyamemazine.
GabapentinThe risk or severity of CNS depression can be increased when Gabapentin is combined with Cyamemazine.
Gabapentin enacarbilThe risk or severity of CNS depression can be increased when Gabapentin enacarbil is combined with Cyamemazine.
Gallamine triethiodideThe risk or severity of CNS depression can be increased when Gallamine triethiodide is combined with Cyamemazine.
gamma-Hydroxybutyric acidThe risk or severity of CNS depression can be increased when gamma-Hydroxybutyric acid is combined with Cyamemazine.
GanaxoloneThe risk or severity of sedation, somnolence, and CNS depression can be increased when Cyamemazine is combined with Ganaxolone.
GepironeThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Gepirone.
GliclazideThe therapeutic efficacy of Gliclazide can be decreased when used in combination with Cyamemazine.
GlimepirideThe therapeutic efficacy of Glimepiride can be decreased when used in combination with Cyamemazine.
GlipizideThe therapeutic efficacy of Glipizide can be decreased when used in combination with Cyamemazine.
GliquidoneThe therapeutic efficacy of Gliquidone can be decreased when used in combination with Cyamemazine.
GlutethimideThe risk or severity of CNS depression can be increased when Glutethimide is combined with Cyamemazine.
GlyburideThe therapeutic efficacy of Glyburide can be decreased when used in combination with Cyamemazine.
GranisetronThe risk or severity of CNS depression can be increased when Granisetron is combined with Cyamemazine.
GuanfacineThe risk or severity of CNS depression can be increased when Guanfacine is combined with Cyamemazine.
HalazepamThe risk or severity of CNS depression can be increased when Halazepam is combined with Cyamemazine.
HalofantrineThe risk or severity of QTc prolongation can be increased when Halofantrine is combined with Cyamemazine.
HaloperidolThe risk or severity of CNS depression can be increased when Haloperidol is combined with Cyamemazine.
HalothaneThe risk or severity of CNS depression can be increased when Halothane is combined with Cyamemazine.
HexafluroniumThe risk or severity of CNS depression can be increased when Hexafluronium is combined with Cyamemazine.
HydrocodoneCyamemazine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
HydromorphoneThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Hydromorphone.
HydrotalciteHydrotalcite can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
HydroxychloroquineThe risk or severity of QTc prolongation can be increased when Hydroxychloroquine is combined with Cyamemazine.
HydroxyzineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine.
HyoscyamineCyamemazine may increase the anticholinergic activities of Hyoscyamine.
IloperidoneThe risk or severity of CNS depression can be increased when Iloperidone is combined with Cyamemazine.
ImipenemImipenem may increase the neurotoxic activities of Cyamemazine.
ImipramineThe serum concentration of Imipramine can be increased when it is combined with Cyamemazine.
Insulin aspartThe therapeutic efficacy of Insulin aspart can be decreased when used in combination with Cyamemazine.
Insulin beefThe therapeutic efficacy of Insulin beef can be decreased when used in combination with Cyamemazine.
Insulin degludecThe therapeutic efficacy of Insulin degludec can be decreased when used in combination with Cyamemazine.
Insulin detemirThe therapeutic efficacy of Insulin detemir can be decreased when used in combination with Cyamemazine.
Insulin glargineThe therapeutic efficacy of Insulin glargine can be decreased when used in combination with Cyamemazine.
Insulin glulisineThe therapeutic efficacy of Insulin glulisine can be decreased when used in combination with Cyamemazine.
Insulin humanThe therapeutic efficacy of Insulin human can be decreased when used in combination with Cyamemazine.
Insulin lisproThe therapeutic efficacy of Insulin lispro can be decreased when used in combination with Cyamemazine.
Insulin porkThe therapeutic efficacy of Insulin pork can be decreased when used in combination with Cyamemazine.
Iofetamine I-123Cyamemazine may decrease the stimulatory activities of Iofetamine I-123.
IsocarboxazidThe risk or severity of extrapyramidal symptoms can be increased when Isocarboxazid is combined with Cyamemazine.
IsofluraneThe risk or severity of CNS depression can be increased when Isoflurane is combined with Cyamemazine.
KetamineThe risk or severity of CNS depression can be increased when Ketamine is combined with Cyamemazine.
KetazolamThe risk or severity of CNS depression can be increased when Ketazolam is combined with Cyamemazine.
LabetalolThe serum concentration of Labetalol can be increased when it is combined with Cyamemazine.
LamotrigineThe risk or severity of CNS depression can be increased when Lamotrigine is combined with Cyamemazine.
LasmiditanThe risk or severity of adverse effects can be increased when Lasmiditan is combined with Cyamemazine.
LemborexantThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Lemborexant.
LevacetylmethadolThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Levacetylmethadol.
LevetiracetamThe risk or severity of CNS depression can be increased when Levetiracetam is combined with Cyamemazine.
LevobetaxololThe serum concentration of Levobetaxolol can be increased when it is combined with Cyamemazine.
LevobupivacaineThe risk or severity of CNS depression can be increased when Levobupivacaine is combined with Cyamemazine.
LevocetirizineThe risk or severity of CNS depression can be increased when Levocetirizine is combined with Cyamemazine.
LevodopaThe risk or severity of CNS depression can be increased when Levodopa is combined with Cyamemazine.
LevomilnacipranThe risk or severity of adverse effects can be increased when Levomilnacipran is combined with Cyamemazine.
LevorphanolThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Levorphanol.
LidocaineThe risk or severity of CNS depression can be increased when Lidocaine is combined with Cyamemazine.
LincomycinLincomycin may increase the neurotoxic activities of Cyamemazine.
LinezolidThe risk or severity of extrapyramidal symptoms can be increased when Linezolid is combined with Cyamemazine.
LisdexamfetamineCyamemazine may decrease the stimulatory activities of Lisdexamfetamine.
LisurideThe risk or severity of CNS depression can be increased when Lisuride is combined with Cyamemazine.
Lithium carbonateLithium carbonate may increase the neurotoxic activities of Cyamemazine.
Lithium citrateLithium citrate may increase the neurotoxic activities of Cyamemazine.
Lithium hydroxideLithium hydroxide may increase the neurotoxic activities of Cyamemazine.
LofexidineThe therapeutic efficacy of Cyamemazine can be increased when used in combination with Lofexidine.
LorazepamThe risk or severity of CNS depression can be increased when Lorazepam is combined with Cyamemazine.
LorcaserinThe risk or severity of adverse effects can be increased when Lorcaserin is combined with Cyamemazine.
LormetazepamThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Lormetazepam.
LorpiprazoleThe risk or severity of adverse effects can be increased when Lorpiprazole is combined with Cyamemazine.
LoxapineThe risk or severity of CNS depression can be increased when Loxapine is combined with Cyamemazine.
LumateperoneThe risk or severity of adverse effects can be increased when Lumateperone is combined with Cyamemazine.
LumefantrineThe risk or severity of QTc prolongation can be increased when Lumefantrine is combined with Cyamemazine.
LurasidoneThe risk or severity of CNS depression can be increased when Lurasidone is combined with Cyamemazine.
MagaldrateMagaldrate can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Magnesium carbonateMagnesium carbonate can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Magnesium hydroxideMagnesium hydroxide can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Magnesium oxideMagnesium oxide can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Magnesium silicateMagnesium silicate can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Magnesium sulfateThe therapeutic efficacy of Cyamemazine can be increased when used in combination with Magnesium sulfate.
Magnesium trisilicateMagnesium trisilicate can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
MaprotilineThe risk or severity of adverse effects can be increased when Maprotiline is combined with Cyamemazine.
MazindolThe risk or severity of adverse effects can be increased when Mazindol is combined with Cyamemazine.
MebutamateThe risk or severity of CNS depression can be increased when Mebutamate is combined with Cyamemazine.
MeclizineThe risk or severity of CNS depression can be increased when Meclizine is combined with Cyamemazine.
MedifoxamineThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Medifoxamine.
MefloquineThe risk or severity of QTc prolongation can be increased when Mefloquine is combined with Cyamemazine.
MelatoninThe risk or severity of CNS depression can be increased when Melatonin is combined with Cyamemazine.
MeperidineThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Meperidine.
MephentermineCyamemazine may decrease the stimulatory activities of Mephentermine.
MephenytoinThe risk or severity of CNS depression can be increased when Mephenytoin is combined with Cyamemazine.
MepivacaineThe risk or severity of CNS depression can be increased when Mepivacaine is combined with Cyamemazine.
MeprobamateThe risk or severity of CNS depression can be increased when Meprobamate is combined with Cyamemazine.
MepyramineThe risk or severity of CNS depression can be increased when Mepyramine is combined with Cyamemazine.
MesoridazineThe risk or severity of CNS depression can be increased when Mesoridazine is combined with Cyamemazine.
MetamfetamineCyamemazine may decrease the stimulatory activities of Metamfetamine.
MetaxaloneThe risk or severity of CNS depression can be increased when Metaxalone is combined with Cyamemazine.
MetergolineThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Metergoline.
MethadoneThe risk or severity of adverse effects can be increased when Methadone is combined with Cyamemazine.
MethocarbamolThe risk or severity of CNS depression can be increased when Methocarbamol is combined with Cyamemazine.
MethohexitalThe risk or severity of CNS depression can be increased when Methohexital is combined with Cyamemazine.
MethotrimeprazineCyamemazine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
MethoxyfluraneThe risk or severity of CNS depression can be increased when Methoxyflurane is combined with Cyamemazine.
MethoxyphenamineCyamemazine may decrease the stimulatory activities of Methoxyphenamine.
MethsuximideThe risk or severity of CNS depression can be increased when Methsuximide is combined with Cyamemazine.
Methylene blueThe risk or severity of extrapyramidal symptoms can be increased when Methylene blue is combined with Cyamemazine.
MethylphenidateThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Methylphenidate.
MethylphenobarbitalThe risk or severity of CNS depression can be increased when Methylphenobarbital is combined with Cyamemazine.
MethyprylonThe risk or severity of CNS depression can be increased when Methyprylon is combined with Cyamemazine.
MethysergideThe risk or severity of CNS depression can be increased when Methysergide is combined with Cyamemazine.
MetoclopramideThe risk or severity of adverse effects can be increased when Metoclopramide is combined with Cyamemazine.
MetocurineThe risk or severity of CNS depression can be increased when Metocurine is combined with Cyamemazine.
Metocurine iodideThe risk or severity of CNS depression can be increased when Metocurine iodide is combined with Cyamemazine.
MetoprololThe serum concentration of Metoprolol can be increased when it is combined with Cyamemazine.
MetyrosineThe risk or severity of extrapyramidal symptoms and CNS depression can be increased when Metyrosine is combined with Cyamemazine.
MianserinThe risk or severity of adverse effects can be increased when Mianserin is combined with Cyamemazine.
MidazolamThe risk or severity of sedation and CNS depression can be increased when Midazolam is combined with Cyamemazine.
MilnacipranThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Milnacipran.
MinaprineThe risk or severity of extrapyramidal symptoms can be increased when Minaprine is combined with Cyamemazine.
MinocyclineMinocycline may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine.
MirtazapineCyamemazine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
MivacuriumThe risk or severity of CNS depression can be increased when Mivacurium is combined with Cyamemazine.
MoclobemideThe risk or severity of extrapyramidal symptoms can be increased when Moclobemide is combined with Cyamemazine.
MolindoneThe risk or severity of CNS depression can be increased when Molindone is combined with Cyamemazine.
MoricizineThe risk or severity of CNS depression can be increased when Moricizine is combined with Cyamemazine.
MorphineThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Morphine.
NabiloneNabilone may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine.
NadololThe serum concentration of Nadolol can be increased when it is combined with Cyamemazine.
NalbuphineThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Nalbuphine.
NaloxegolThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Naloxegol.
NaltrexoneThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Naltrexone.
NaphazolineThe risk or severity of CNS depression can be increased when Naphazoline is combined with Cyamemazine.
NaratriptanThe risk or severity of adverse effects can be increased when Naratriptan is combined with Cyamemazine.
NaxitamabCyamemazine may increase the neurotoxic activities of Naxitamab.
NebivololThe serum concentration of Nebivolol can be increased when it is combined with Cyamemazine.
NefazodoneThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Nefazodone.
NeomycinNeomycin may increase the neurotoxic activities of Cyamemazine.
NialamideThe risk or severity of extrapyramidal symptoms can be increased when Nialamide is combined with Cyamemazine.
NitrazepamThe risk or severity of CNS depression can be increased when Nitrazepam is combined with Cyamemazine.
Nitrous oxideThe risk or severity of CNS depression can be increased when Nitrous oxide is combined with Cyamemazine.
NomifensineThe risk or severity of CNS depression can be increased when Nomifensine is combined with Cyamemazine.
NormethadoneThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Normethadone.
NortriptylineThe serum concentration of Nortriptyline can be increased when it is combined with Cyamemazine.
OlanzapineThe risk or severity of CNS depression can be increased when Olanzapine is combined with Cyamemazine.
OliceridineThe risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Cyamemazine is combined with Oliceridine.
OndansetronThe risk or severity of CNS depression can be increased when Ondansetron is combined with Cyamemazine.
OpiumThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Opium.
OrphenadrineCyamemazine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
OxazepamThe risk or severity of CNS depression can be increased when Oxazepam is combined with Cyamemazine.
OxcarbazepineThe risk or severity of CNS depression can be increased when Oxcarbazepine is combined with Cyamemazine.
OxitriptanThe risk or severity of CNS depression can be increased when Oxitriptan is combined with Cyamemazine.
OxprenololThe serum concentration of Oxprenolol can be increased when it is combined with Cyamemazine.
OxybuprocaineThe risk or severity of CNS depression can be increased when Oxybuprocaine is combined with Cyamemazine.
OxycodoneThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Oxycodone.
OxymorphoneThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Oxymorphone.
PaclitaxelPaclitaxel may increase the neurotoxic activities of Cyamemazine.
PadeliporfinCyamemazine may increase the photosensitizing activities of Padeliporfin.
PaliperidoneThe risk or severity of CNS depression can be increased when Paliperidone is combined with Cyamemazine.
PalonosetronThe risk or severity of CNS depression can be increased when Palonosetron is combined with Cyamemazine.
PancuroniumThe risk or severity of CNS depression can be increased when Pancuronium is combined with Cyamemazine.
ParaldehydeCyamemazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ParamethadioneThe risk or severity of CNS depression can be increased when Paramethadione is combined with Cyamemazine.
PargylineThe risk or severity of extrapyramidal symptoms can be increased when Pargyline is combined with Cyamemazine.
ParoxetineThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Paroxetine.
PenbutololThe serum concentration of Penbutolol can be increased when it is combined with Cyamemazine.
PentazocineThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Pentazocine.
PentobarbitalThe risk or severity of CNS depression can be increased when Pentobarbital is combined with Cyamemazine.
PerampanelPerampanel may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine.
PerazineThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Perazine.
PergolideThe risk or severity of CNS depression can be increased when Pergolide is combined with Cyamemazine.
PericiazineThe risk or severity of CNS depression can be increased when Periciazine is combined with Cyamemazine.
PerphenazineThe risk or severity of CNS depression can be increased when Perphenazine is combined with Cyamemazine.
PhenacemideThe risk or severity of CNS depression can be increased when Phenacemide is combined with Cyamemazine.
PhendimetrazineCyamemazine may decrease the stimulatory activities of Phendimetrazine.
PhenelzineThe risk or severity of extrapyramidal symptoms can be increased when Phenelzine is combined with Cyamemazine.
PhenobarbitalThe risk or severity of CNS depression can be increased when Phenobarbital is combined with Cyamemazine.
PhensuximideThe risk or severity of CNS depression can be increased when Phensuximide is combined with Cyamemazine.
PhentermineCyamemazine may decrease the stimulatory activities of Phentermine.
PhenytoinThe serum concentration of Phenytoin can be increased when it is combined with Cyamemazine.
PimavanserinPimavanserin may increase the neurotoxic activities of Cyamemazine.
PimozideThe risk or severity of CNS depression can be increased when Pimozide is combined with Cyamemazine.
PindololThe serum concentration of Pindolol can be increased when it is combined with Cyamemazine.
PipecuroniumThe risk or severity of CNS depression can be increased when Pipecuronium is combined with Cyamemazine.
PiperaquineThe risk or severity of QTc prolongation can be increased when Piperaquine is combined with Cyamemazine.
PipotiazineThe risk or severity of CNS depression can be increased when Pipotiazine is combined with Cyamemazine.
PiritramideThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Piritramide.
PizotifenThe risk or severity of CNS depression can be increased when Pizotifen is combined with Cyamemazine.
Polymyxin BCyamemazine may increase the neurotoxic activities of Polymyxin B.
PomalidomideThe risk or severity of CNS depression can be increased when Pomalidomide is combined with Cyamemazine.
Porfimer sodiumCyamemazine may increase the photosensitizing activities of Porfimer sodium.
PractololThe serum concentration of Practolol can be increased when it is combined with Cyamemazine.
PramipexoleCyamemazine may increase the sedative activities of Pramipexole.
PramocaineThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Pramocaine.
PrazepamThe risk or severity of CNS depression can be increased when Prazepam is combined with Cyamemazine.
PregabalinThe therapeutic efficacy of Cyamemazine can be increased when used in combination with Pregabalin.
PrilocaineThe risk or severity of CNS depression can be increased when Prilocaine is combined with Cyamemazine.
PrimaquineThe risk or severity of QTc prolongation can be increased when Primaquine is combined with Cyamemazine.
PrimidoneThe risk or severity of CNS depression can be increased when Primidone is combined with Cyamemazine.
ProcaineThe risk or severity of extrapyramidal symptoms can be increased when Procaine is combined with Cyamemazine.
ProcarbazineThe risk or severity of extrapyramidal symptoms can be increased when Procarbazine is combined with Cyamemazine.
ProchlorperazineThe risk or severity of CNS depression can be increased when Prochlorperazine is combined with Cyamemazine.
ProguanilThe risk or severity of QTc prolongation can be increased when Proguanil is combined with Cyamemazine.
PromazineThe risk or severity of CNS depression can be increased when Promazine is combined with Cyamemazine.
PromethazineThe risk or severity of adverse effects can be increased when Promethazine is combined with Cyamemazine.
PropafenoneThe serum concentration of Propafenone can be increased when it is combined with Cyamemazine.
PropiomazineThe risk or severity of CNS depression can be increased when Propiomazine is combined with Cyamemazine.
PropofolThe risk or severity of CNS depression can be increased when Propofol is combined with Cyamemazine.
PropranololThe serum concentration of Propranolol can be increased when it is combined with Cyamemazine.
ProtriptylineThe serum concentration of Protriptyline can be increased when it is combined with Cyamemazine.
ProxibarbalThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Proxibarbal.
PseudoephedrineCyamemazine may decrease the stimulatory activities of Pseudoephedrine.
PyrantelThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Pyrantel.
PyrimethamineThe risk or severity of QTc prolongation can be increased when Pyrimethamine is combined with Cyamemazine.
QuazepamThe risk or severity of CNS depression can be increased when Quazepam is combined with Cyamemazine.
QuetiapineThe risk or severity of CNS depression can be increased when Quetiapine is combined with Cyamemazine.
QuinagolideThe therapeutic efficacy of Quinagolide can be decreased when used in combination with Cyamemazine.
QuinidineThe risk or severity of QTc prolongation can be increased when Quinidine is combined with Cyamemazine.
QuinineThe risk or severity of QTc prolongation can be increased when Quinine is combined with Cyamemazine.
QuinupramineThe serum concentration of Quinupramine can be increased when it is combined with Cyamemazine.
RamelteonThe risk or severity of CNS depression can be increased when Ramelteon is combined with Cyamemazine.
RapacuroniumThe risk or severity of CNS depression can be increased when Rapacuronium is combined with Cyamemazine.
RasagilineThe risk or severity of extrapyramidal symptoms can be increased when Rasagiline is combined with Cyamemazine.
ReboxetineThe risk or severity of CNS depression can be increased when Reboxetine is combined with Cyamemazine.
RemifentanilThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Remifentanil.
RemimazolamThe risk or severity of sedation can be increased when Cyamemazine is combined with Remimazolam.
RemoxiprideThe risk or severity of CNS depression can be increased when Remoxipride is combined with Cyamemazine.
ReserpineThe risk or severity of CNS depression can be increased when Reserpine is combined with Cyamemazine.
RiluzoleThe risk or severity of CNS depression can be increased when Riluzole is combined with Cyamemazine.
RimonabantThe risk or severity of adverse effects can be increased when Rimonabant is combined with Cyamemazine.
RisperidoneThe risk or severity of CNS depression can be increased when Risperidone is combined with Cyamemazine.
RizatriptanThe risk or severity of adverse effects can be increased when Rizatriptan is combined with Cyamemazine.
RocuroniumThe risk or severity of CNS depression can be increased when Rocuronium is combined with Cyamemazine.
Ropeginterferon alfa-2bThe risk or severity of neuropsychiatric effects can be increased when Ropeginterferon alfa-2b is combined with Cyamemazine.
RopiniroleCyamemazine may increase the sedative activities of Ropinirole.
RopivacaineThe risk or severity of CNS depression can be increased when Ropivacaine is combined with Cyamemazine.
RotigotineCyamemazine may increase the sedative activities of Rotigotine.
RufinamideThe risk or severity of adverse effects can be increased when Rufinamide is combined with Cyamemazine.
SafinamideThe risk or severity of extrapyramidal symptoms can be increased when Safinamide is combined with Cyamemazine.
SamidorphanThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Samidorphan.
ScopolamineThe risk or severity of CNS depression can be increased when Scopolamine is combined with Cyamemazine.
SecobarbitalThe risk or severity of CNS depression can be increased when Secobarbital is combined with Cyamemazine.
SelegilineThe risk or severity of extrapyramidal symptoms can be increased when Selegiline is combined with Cyamemazine.
SertindoleThe risk or severity of CNS depression can be increased when Sertindole is combined with Cyamemazine.
SertralineThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Sertraline.
SevofluraneThe risk or severity of CNS depression can be increased when Sevoflurane is combined with Cyamemazine.
SibutramineThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Sibutramine.
Sodium bicarbonateSodium bicarbonate can cause a decrease in the absorption of Cyamemazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sodium citrateCyamemazine may increase the neurotoxic activities of Sodium citrate.
Sodium oxybateCyamemazine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
SolriamfetolThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Solriamfetol.
SotalolThe serum concentration of Sotalol can be increased when it is combined with Cyamemazine.
St. John's WortThe risk or severity of CNS depression can be increased when St. John's Wort is combined with Cyamemazine.
StavudineStavudine may increase the neurotoxic activities of Cyamemazine.
StiripentolThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Stiripentol.
SuccinylcholineThe risk or severity of CNS depression can be increased when Succinylcholine is combined with Cyamemazine.
SufentanilThe risk or severity of hypotension and CNS depression can be increased when Cyamemazine is combined with Sufentanil.
SulfadoxineThe risk or severity of QTc prolongation can be increased when Sulfadoxine is combined with Cyamemazine.
SulpirideCyamemazine may increase the antipsychotic activities of Sulpiride.
SulthiameThe risk or severity of CNS depression can be increased when Sulthiame is combined with Cyamemazine.
SultoprideThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Sultopride.
SumatriptanThe risk or severity of adverse effects can be increased when Sumatriptan is combined with Cyamemazine.
SuvorexantCyamemazine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
TafenoquineThe risk or severity of QTc prolongation can be increased when Tafenoquine is combined with Cyamemazine.
TalbutalThe risk or severity of CNS depression can be increased when Talbutal is combined with Cyamemazine.
TapentadolTapentadol may increase the central nervous system depressant (CNS depressant) activities of Cyamemazine.
TasimelteonThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Tasimelteon.
TemazepamThe risk or severity of CNS depression can be increased when Temazepam is combined with Cyamemazine.
TeniposideTeniposide may increase the neurotoxic activities of Cyamemazine.
TetrabenazineThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Tetrabenazine.
TetracaineThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Tetracaine.
ThalidomideCyamemazine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
ThiamylalThe risk or severity of CNS depression can be increased when Thiamylal is combined with Cyamemazine.
ThiethylperazineThe risk or severity of CNS depression can be increased when Thiethylperazine is combined with Cyamemazine.
ThiopentalThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Thiopental.
ThioridazineThe risk or severity of CNS depression can be increased when Thioridazine is combined with Cyamemazine.
ThiothixeneThe risk or severity of CNS depression can be increased when Thiothixene is combined with Cyamemazine.
TiagabineThe risk or severity of CNS depression can be increased when Tiagabine is combined with Cyamemazine.
TimololThe serum concentration of Timolol can be increased when it is combined with Cyamemazine.
TizanidineThe risk or severity of CNS depression can be increased when Tizanidine is combined with Cyamemazine.
TolazamideThe therapeutic efficacy of Tolazamide can be decreased when used in combination with Cyamemazine.
TolbutamideThe therapeutic efficacy of Tolbutamide can be decreased when used in combination with Cyamemazine.
TolcaponeThe risk or severity of CNS depression can be increased when Tolcapone is combined with Cyamemazine.
TopiramateThe risk or severity of CNS depression can be increased when Topiramate is combined with Cyamemazine.
TramadolThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Tramadol.
TranylcypromineThe risk or severity of extrapyramidal symptoms can be increased when Tranylcypromine is combined with Cyamemazine.
TrazodoneThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Trazodone.
TretinoinThe risk or severity of adverse effects can be increased when Tretinoin is combined with Cyamemazine.
TriazolamThe risk or severity of CNS depression can be increased when Triazolam is combined with Cyamemazine.
TrichloroethyleneThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Trichloroethylene.
TriclofosThe risk or severity of CNS depression can be increased when Triclofos is combined with Cyamemazine.
TrifluoperazineThe risk or severity of CNS depression can be increased when Trifluoperazine is combined with Cyamemazine.
TriflupromazineThe risk or severity of CNS depression can be increased when Triflupromazine is combined with Cyamemazine.
TrimethadioneThe risk or severity of CNS depression can be increased when Trimethadione is combined with Cyamemazine.
TrimethobenzamideThe risk or severity of CNS depression can be increased when Trimethobenzamide is combined with Cyamemazine.
TrimipramineThe serum concentration of Trimipramine can be increased when it is combined with Cyamemazine.
TriprolidineThe risk or severity of CNS depression can be increased when Triprolidine is combined with Cyamemazine.
TropisetronThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Tropisetron.
TryptophanThe risk or severity of CNS depression can be increased when Tryptophan is combined with Cyamemazine.
TubocurarineThe risk or severity of CNS depression can be increased when Tubocurarine is combined with Cyamemazine.
UrethaneThe risk or severity of CNS depression can be increased when Urethane is combined with Cyamemazine.
Valproate bismuthCyamemazine may increase the neurotoxic activities of Valproate bismuth.
Valproic acidThe risk or severity of CNS depression can be increased when Valproic acid is combined with Cyamemazine.
VecuroniumThe risk or severity of CNS depression can be increased when Vecuronium is combined with Cyamemazine.
VenlafaxineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Cyamemazine.
VerteporfinCyamemazine may increase the photosensitizing activities of Verteporfin.
VigabatrinThe risk or severity of CNS depression can be increased when Vigabatrin is combined with Cyamemazine.
VilazodoneThe risk or severity of adverse effects can be increased when Vilazodone is combined with Cyamemazine.
ViloxazineThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Viloxazine.
VincristineVincristine may increase the neurotoxic activities of Cyamemazine.
VinorelbineVinorelbine may increase the neurotoxic activities of Cyamemazine.
ViomycinViomycin may increase the neurotoxic activities of Cyamemazine.
VortioxetineThe risk or severity of adverse effects can be increased when Vortioxetine is combined with Cyamemazine.
YohimbineThe therapeutic efficacy of Cyamemazine can be increased when used in combination with Yohimbine.
ZaleplonThe risk or severity of CNS depression can be increased when Zaleplon is combined with Cyamemazine.
ZiconotideThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Ziconotide.
ZimelidineThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Zimelidine.
ZiprasidoneThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Ziprasidone.
ZolmitriptanThe risk or severity of adverse effects can be increased when Zolmitriptan is combined with Cyamemazine.
ZolpidemCyamemazine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
ZonisamideThe risk or severity of CNS depression can be increased when Zonisamide is combined with Cyamemazine.
ZopicloneThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Zopiclone.
ZotepineThe risk or severity of CNS depression can be increased when Cyamemazine is combined with Zotepine.
ZuclopenthixolThe risk or severity of CNS depression can be increased when Zuclopenthixol is combined with Cyamemazine.
ZuranoloneThe risk or severity of CNS depression can be increased when Zuranolone is combined with Cyamemazine.
Food Interactions
Not Available

Products

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International/Other Brands
Tercian (Sanofi-Aventis)

Categories

ATC Codes
N05AA06 — Cyamemazine
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as phenothiazines. These are polycyclic aromatic compounds containing a phenothiazine moiety, which is a linear tricyclic system that consists of a two benzene rings joined by a para-thiazine ring.
Kingdom
Organic compounds
Super Class
Organoheterocyclic compounds
Class
Benzothiazines
Sub Class
Phenothiazines
Direct Parent
Phenothiazines
Alternative Parents
Alkyldiarylamines / Diarylthioethers / Benzenoids / 1,4-thiazines / Trialkylamines / Nitriles / Azacyclic compounds / Organopnictogen compounds / Hydrocarbon derivatives
Substituents
Alkyldiarylamine / Amine / Aromatic heteropolycyclic compound / Aryl thioether / Azacycle / Benzenoid / Carbonitrile / Diarylthioether / Hydrocarbon derivative / Nitrile
Molecular Framework
Aromatic heteropolycyclic compounds
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
A2JGV5CNU4
CAS number
3546-03-0
InChI Key
SLFGIOIONGJGRT-UHFFFAOYSA-N
InChI
InChI=1S/C19H21N3S/c1-14(12-21(2)3)13-22-16-6-4-5-7-18(16)23-19-9-8-15(11-20)10-17(19)22/h4-10,14H,12-13H2,1-3H3
IUPAC Name
10-[3-(dimethylamino)-2-methylpropyl]-10H-phenothiazine-2-carbonitrile
SMILES
CC(CN(C)C)CN1C2=CC=CC=C2SC2=C1C=C(C=C2)C#N

References

Synthesis Reference

U.S. Patent 2,877,224.

General References
Not Available
KEGG Drug
D07307
PubChem Compound
62865
PubChem Substance
310264961
ChemSpider
56597
BindingDB
86057
RxNav
21877
ChEBI
135379
ChEMBL
CHEMBL2104153
Drugs.com
Drugs.com Drug Page
Wikipedia
Cyamemazine

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
PropertyValueSource
melting point (°C)204-205U.S. Patent 2,877,224.
Predicted Properties
PropertyValueSource
Water Solubility0.029 mg/mLALOGPS
logP4.28ALOGPS
logP4.27Chemaxon
logS-4ALOGPS
pKa (Strongest Basic)9.42Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area30.27 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity99.09 m3·mol-1Chemaxon
Polarizability36.48 Å3Chemaxon
Number of Rings3Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSsplash10-052r-4091000000-8fd4f49543d5acc4171d
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-0fk9-0809000000-e9a47ba9e9b612c317f0
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-00di-0029000000-688c415606fcea11bb52
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-00di-0029000000-bace050610190a6af660
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-0q29-9355000000-66285b2e31caa1879c98
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-00dr-0190000000-0d53fef3947fb7c85f1c
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-056r-5290000000-0730f877de6790187b95
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-167.3835
predicted
DeepCCS 1.0 (2019)
[M+H]+169.7415
predicted
DeepCCS 1.0 (2019)
[M+Na]+176.07875
predicted
DeepCCS 1.0 (2019)

Drug created at June 17, 2014 16:28 / Updated at February 21, 2021 18:52