| Interpretado por | Personaje | Temporada | |||
|---|---|---|---|---|---|
| 1 | 2 | 3 | |||
| Personajes principales | |||||
| Winona Ryder | Joyce Byers | Principal | |||
| David Harbour | Jim Hopper | Principal | |||
| Finn Wolfhard | Mike Wheeler | Principal | |||
| Millie Bobby Brown | Once / Jane Hopper | Principal | |||
| Gaten Matarazzo | Dustin Henderson | Principal | |||
| Caleb McLaughlin | Lucas Sinclair | Principal | |||
| Natalia Dyer | Nancy Wheeler | Principal | |||
| Charlie Heaton | Jonathan Byers | Principal | |||
| Cara Buono | Karen Wheeler | Principal | |||
| Matthew Modine | Martin Brenner | Principal | Secundario | ||
| Noah Schnapp | Will Byers | Secundario | Principal | ||
| Joe Keery | Steve Harrington | Secundario | Principal | ||
| Sadie Sink | Maxine Mayfield | Principal | |||
| Dacre Montgomery | Billy Hargrove † | Principal | |||
| Sean Astin | Bob Newby † | Principal | Invitado | ||
| Paul Reiser | Sam Owens | Principal | Invitado | ||
| Priah Ferguson | Erica Sinclair | Secundaria | Principal | ||
| Maya Hawke | Robin Buckley | Principal | |||
| Personajes secundarios e invitados | |||||
| Joe Chrest | Ted Wheeler | Secundario | |||
| Rob Morgan | Calvin Powell | Secundario | Invitado | ||
| Ross Partridge | Lonnie Byers | Invitado | |||
| Shannon Purser | Barb Holland † | Secundaria | |||
| John Reynolds | Phil Callahan | Secundario | Invitado | ||
| Mark Steger | El Demogorgon | Secundario | Invitado | ||
| Catherine Dyer | Connie Frazier | Secundaria | |||
| Randy Havens | Scott Clarke | Secundario | Invitado | ||
| Tobias Jelinek | Agente líder | Secundario | |||
| Cade Jones | James Dante | Secundario | |||
| Anniston Price | Holly Wheeler | Secundaria | Invitada | Secundaria | |
| Tinsley Price | Secundaria | ||||
| Susan Shalhoub Larkin | Florence | Secundaria | Invitada | ||
| Tony Vaughn | Russell Coleman | Secundario | Invitado | ||
| Charles Lawlor | Donald Melvald | Secundario | Invitado | ||
| Chester Rushing | Tommy Hagan "Tommy H." | Secundario | |||
| Chelsea Talmadge | Carol Perkins | Secundaria | Invitada | ||
| Cynthia Barrett | Marsha Holland | Invitada | Secundaria | ||
| Aimee Mullins | Terry Ives | Invitada | Secundaria | ||
| Amy Seimetz | Becky Ives | Invitada | Secundaria | ||
| Brett Gelman | Murray Bauman | Secundario | |||
| Linnea Berthelsen | Kali / Ocho | Secundaria | |||
| Catherine Curtin | Claudia Henderson | Secundaria | Invitada | ||
| Alec Utgoff | Alexei † | Secundario | |||
| Cary Elwes | Alcalde Larry Kline | Secundario | |||
| Andrey Ivchenko | Grigori | Secundario | |||
| Francesca Reale | Heather Holloway | Secundaria | |||
| Peggy Miley | Doris Driscoll † | Secundaria | |||
| Michael Park | Tom Holloway | Secundario | |||
| Jake Busey | Bruce Lowe | Secundario | |||
| Gabriella Pizzolo | Suzie | Invitada | |||
Estos son los nombres de todos los actores de la serie, a quienes interpretan y que son durante las temporadas.
