Clonidine

Identification

Summary

Clonidine is an alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines.

Brand Names

Catapres, Catapres-TTS, Catapres-tts-1, Duraclon, Kapvay, Nexiclon XR

Generic Name

Clonidine

DrugBank Accession Number

DB00575

Background

Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors.² This activity is useful for the treatment of hypertension, severe pain, and ADHD.^8,9,10,11

Clonidine was granted FDA approval on 3 September 1974.⁸

Type

Small Molecule

Groups

Approved

Structure

3D

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MOLSDF3D-SDFPDBSMILESInChI

Similar Structures

Structure for Clonidine (DB00575)

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Weight

Average: 230.094
Monoisotopic: 229.017352717

Chemical Formula

C₉H₉Cl₂N₃

Synonyms

• 2-((2,6-Dichlorophenyl)imino)imidazolidine
• 2,6-Dichloro-N-2-imidazolidinylidenebenzenamine
• Chlofazoline
• Clonidin
• Clonidina
• Clonidine
• Clonidinum

External IDs

• M-5041T
• SKF 34427
• ST 155
• ST 155-BS

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Pharmacology

Indication

Clonidine tablets and transdermal systems are indicated for the treatment of hypertension alone or in combination with other medications.^8,9 A clonidine injection is indicated for use with opiates in the treatment of severe cancer pain where opiates alone are insufficient.¹⁰ An extended release tablet of clonidine is indicated for the treatment of ADHD either alone or in combination with other medications.¹¹

Clonidine is also used for the diagnosis of pheochromocytoma,³ treatment of nicotine dependance,⁴ and opiate withdrawal.⁵

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Associated Conditions

Indication Type	Indication	Combined Product Details	Approval Level	Age Group	Patient Characteristics	Dose Form
Management of	Adhd		••••••••••••			••• ••••••••••• •••••••• •••••••• •••••• •••••••• •••••••• ••••••• •••••••• •••••••
Diagnostic agent	Growth hormone deficiency		••• •••••
Management of	Hot flashes		••• •••••
Management of	Hypertension		••••••••••••			••••••• •••••
Symptomatic treatment of	Opioid withdrawal		••• •••••
Management of	Oppositional defiant disorder		••• •••••
Diagnostic agent	Pheochromocytoma		••• •••••
Management of	Postherpetic neuralgia		••• •••••
Treatment of	Sialorrhea caused by clozapine		••• •••••
Management of	Tourette syndrome		••• •••••
Management of	Diabetic diarrhea		••• •••••
Symptomatic treatment of	Methadone withdrawal		••• •••••
Management of	Severe cancer pain		••••••••••••

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Associated Therapies

• Smoking, Cessation

Contraindications & Blackbox Warnings

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Pharmacodynamics

Clonidine functions through agonism of alpha-2 adrenoceptors which have effects such as lowering blood pressure, sedation, and hyperpolarization of nerves.² It has a long duration of action as it is given twice daily and the therapeutic window is between 0.1mg and 2.4mg daily.^8,9,10,11

Mechanism of action

Clonidine is primarily an alpha-2 adrenoceptor agonist which causes central hypotensive and anti-arrhythmogenic effects.² The alpha-2 adrenoceptor is coupled to the G-proteins G_o and G_i.² G_i inhibits adenylyl cyclase and activates opening of a potassium channel that causes hyperpolarization.² Clonidine binding to the alpha-2 adrenoceptor causes structural changes in the alpha subunit of the G-protein, reducing its affinity for GDP.² Magnesium catalyzes the replacement of GDP with GTP.² The alpha subunit dissociates from the other subunits and associates with an effector.²

The stimulation of alpha-2 adrenoceptors in the locus coeruleus may be responsible for the hypnotic effects of clonidine as this region of the brain helps regulate wakefulness.² Clonidine can also decrease transmission of pain signals at the spine.² Finally clonidine can affect regulators of blood pressure in the ventromedial and rostral-ventrolateral areas of the medulla.²

Target	Actions	Organism
AAlpha-2B adrenergic receptor	agonist	Humans
AAlpha-2C adrenergic receptor	agonist	Humans
AAlpha-2A adrenergic receptor	agonist	Humans
UAlpha-1A adrenergic receptor	agonist	Humans
UAlpha-1B adrenergic receptor	agonist	Humans
UAlpha-1D adrenergic receptor	agonist	Humans

Absorption

Clonidine reaches maximum concentration in 60-90 minutes after oral administration.^2,6 Race and fasting status do not influence pharmacokinetics of clonidine.⁸

A 100µg oral clonidine tablet reaches a C_max of 400.72pg/mL with an AUC of 5606.78h*pg/mL and a bioavailability of 55-87%.⁶

Volume of distribution

The volume of distribution of clonidine has been reported as 1.7-2.5L/kg², 2.9L/kg⁹, or 2.1±0.4L/kg¹⁰ depending on the source.

Protein binding

Clonidine is 20-40% bound to plasma proteins, especially albumin.^2,10

Metabolism

The metabolism of clonidine is poorly understood.⁷ The main reaction in clonidine metabolism is the 4-hydroxylation of clonidine by CYP2D6, CYP1A2, CYP3A4, CYP1A1, and CYP3A5.⁷

Clonidine is <50% metabolized in the liver to inactive metabolites.^2,8,9,10,11

Hover over products below to view reaction partners

• Clonidine
  • 4-Hydroxyclonidine

Route of elimination

Approximately 50% of a clonidine dose is excreted in the urine as the unchanged drug and 20% is eliminated in the feces.^2,8

Half-life

The elimination half life after epidural administration is 30 minutes but otherwise can range from 6-23h.²

Clearance

The clearance of clonidine is 1.9-4.3mL/min/kg.²

Adverse Effects

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Toxicity

Oral LD₅₀ is 126 mg/kg in rats.¹² The TDLO is 70µg/kg in children, 126µg/kg in women, and 69µg/kg in men.¹²

Symptoms of overdose include hypertension followed by hypotension, bradycardia, respiratory depression, hypothermia, drowsiness, decreased reflexes, weakness, irritability, and miosis.^8,9,10,11 Severe overdoses can cause reversible cardiac conduction defects or dysrhythmias, apnea, coma, and seizures.^8,9,10,11 Induction of vomiting is not recommended due to CNS depression but gastric lavage or activated charcoal may be useful in recent ingestion.^8,9,10,11 Dialysis is also unlikely to be beneficial.^8,9,10,11 Overdose can be treated with supportive measures such as atropine sulfate for bradycardia, intravenous fluids or vasopressors for hypotension, vasodilators for hypertension, naloxone for respiratory depression, and blood pressure monitoring.^8,9,10,11

Pathways

Not Available

Pharmacogenomic Effects/ADRs

Not Available

Interactions

Drug Interactions

This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.

• Approved
• Vet approved
• Nutraceutical
• Illicit
• Withdrawn
• Investigational
• Experimental
• All Drugs

Drug	Interaction
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1,2-Benzodiazepine	The risk or severity of sedation can be increased when Clonidine is combined with 1,2-Benzodiazepine.
Abaloparatide	The risk or severity of adverse effects can be increased when Clonidine is combined with Abaloparatide.
Abametapir	The serum concentration of Clonidine can be increased when it is combined with Abametapir.
Abatacept	The metabolism of Clonidine can be increased when combined with Abatacept.
Abiraterone	The metabolism of Clonidine can be decreased when combined with Abiraterone.
Acalabrutinib	The metabolism of Clonidine can be decreased when combined with Acalabrutinib.
Acebutolol	The risk or severity of hypotension can be increased when Clonidine is combined with Acebutolol.
Aceclofenac	The therapeutic efficacy of Clonidine can be decreased when used in combination with Aceclofenac.
Acemetacin	The therapeutic efficacy of Clonidine can be decreased when used in combination with Acemetacin.
Acenocoumarol	The metabolism of Acenocoumarol can be decreased when combined with Clonidine.
Acetaminophen	The metabolism of Clonidine can be increased when combined with Acetaminophen.
Acetazolamide	The risk or severity of sedation can be increased when Clonidine is combined with Acetazolamide.
Acetophenazine	The risk or severity of sedation can be increased when Clonidine is combined with Acetophenazine.
Acetyldigitoxin	Clonidine may increase the atrioventricular blocking (AV block) activities of Acetyldigitoxin.
Acetylsalicylic acid	Acetylsalicylic acid may decrease the antihypertensive activities of Clonidine.
Aclidinium	The risk or severity of Tachycardia can be increased when Clonidine is combined with Aclidinium.
Acyclovir	The metabolism of Acyclovir can be decreased when combined with Clonidine.
Adagrasib	The serum concentration of Clonidine can be increased when it is combined with Adagrasib.
Adalimumab	The metabolism of Clonidine can be increased when combined with Adalimumab.
Adenosine	The risk or severity of Tachycardia can be increased when Clonidine is combined with Adenosine.
Agomelatine	The risk or severity of sedation can be increased when Clonidine is combined with Agomelatine.
Albendazole	The metabolism of Clonidine can be increased when combined with Albendazole.
Albuterol	Salbutamol may decrease the antihypertensive activities of Clonidine.
Alclofenac	The therapeutic efficacy of Clonidine can be decreased when used in combination with Alclofenac.
Aldesleukin	The serum concentration of Clonidine can be increased when it is combined with Aldesleukin.
Alfentanil	The risk or severity of sedation can be increased when Clonidine is combined with Alfentanil.
Alfuzosin	Alfuzosin may increase the hypotensive activities of Clonidine.
Alimemazine	The risk or severity of sedation can be increased when Clonidine is combined with Alimemazine.
Aliskiren	The risk or severity of hypotension can be increased when Clonidine is combined with Aliskiren.
Almotriptan	The risk or severity of sedation can be increased when Clonidine is combined with Almotriptan.
Alogliptin	The metabolism of Clonidine can be decreased when combined with Alogliptin.
Alosetron	The risk or severity of sedation can be increased when Clonidine is combined with Alosetron.
Alpelisib	The metabolism of Clonidine can be increased when combined with Alpelisib.
Alprazolam	The risk or severity of sedation can be increased when Clonidine is combined with Alprazolam.
Alverine	The risk or severity of sedation can be increased when Clonidine is combined with Alverine.
Ambrisentan	The risk or severity of hypotension can be increased when Clonidine is combined with Ambrisentan.
Amifostine	Clonidine may increase the hypotensive activities of Amifostine.
Amiloride	The risk or severity of adverse effects can be increased when Clonidine is combined with Amiloride.
Aminoglutethimide	The metabolism of Clonidine can be increased when combined with Aminoglutethimide.
Aminophenazone	The metabolism of Clonidine can be decreased when combined with Aminophenazone.
Aminophylline	The metabolism of Aminophylline can be decreased when combined with Clonidine.
Amiodarone	Clonidine may increase the atrioventricular blocking (AV block) activities of Amiodarone.
Amisulpride	The risk or severity of sedation can be increased when Clonidine is combined with Amisulpride.
Amitriptyline	The risk or severity of sedation can be increased when Clonidine is combined with Amitriptyline.
Amitriptylinoxide	The risk or severity of sedation can be increased when Clonidine is combined with Amitriptylinoxide.
Amlodipine	The risk or severity of hypotension can be increased when Clonidine is combined with Amlodipine.
Amobarbital	The risk or severity of sedation can be increased when Clonidine is combined with Amobarbital.
Amoxapine	The risk or severity of sedation can be increased when Clonidine is combined with Amoxapine.
Amphetamine	The metabolism of Clonidine can be decreased when combined with Amphetamine.
Amphotericin B	The risk or severity of adverse effects can be increased when Clonidine is combined with Amphotericin B.
Amprenavir	The metabolism of Clonidine can be decreased when combined with Amprenavir.
Amyl Nitrite	The risk or severity of adverse effects can be increased when Clonidine is combined with Amyl Nitrite.
Anagrelide	The metabolism of Clonidine can be decreased when combined with Anagrelide.
Anakinra	The metabolism of Clonidine can be increased when combined with Anakinra.
Anileridine	The therapeutic efficacy of Anileridine can be increased when used in combination with Clonidine.
Anisotropine methylbromide	The risk or severity of Tachycardia can be increased when Anisotropine methylbromide is combined with Clonidine.
Antipyrine	The metabolism of Clonidine can be decreased when combined with Antipyrine.
Antrafenine	The therapeutic efficacy of Clonidine can be decreased when used in combination with Antrafenine.
Apalutamide	The serum concentration of Clonidine can be decreased when it is combined with Apalutamide.
Apixaban	The metabolism of Clonidine can be decreased when combined with Apixaban.
Apomorphine	The risk or severity of sedation can be increased when Clonidine is combined with Apomorphine.
Apremilast	The metabolism of Clonidine can be increased when combined with Apremilast.
Aprepitant	The metabolism of Clonidine can be decreased when combined with Aprepitant.
Apronalide	The risk or severity of sedation can be increased when Clonidine is combined with Apronalide.
Arbutamine	Arbutamine may decrease the antihypertensive activities of Clonidine.
Arformoterol	The metabolism of Clonidine can be decreased when combined with Arformoterol.
Aripiprazole	The risk or severity of sedation can be increased when Clonidine is combined with Aripiprazole.
Aripiprazole lauroxil	The risk or severity of sedation can be increased when Clonidine is combined with Aripiprazole lauroxil.
Armodafinil	The metabolism of Clonidine can be increased when combined with Armodafinil.
Arsenic trioxide	The risk or severity of adverse effects can be increased when Clonidine is combined with Arsenic trioxide.
Artemether	The metabolism of Clonidine can be decreased when combined with Artemether.
Artenimol	The metabolism of Clonidine can be decreased when combined with Artenimol.
Articaine	The risk or severity of sedation can be increased when Clonidine is combined with Articaine.
Asciminib	The serum concentration of Clonidine can be increased when it is combined with Asciminib.
Asenapine	The risk or severity of sedation can be increased when Clonidine is combined with Asenapine.
Astemizole	The serum concentration of Clonidine can be increased when it is combined with Astemizole.
Asunaprevir	The metabolism of Clonidine can be decreased when combined with Asunaprevir.
Atazanavir	The metabolism of Clonidine can be decreased when combined with Atazanavir.
Atenolol	The risk or severity of hypotension can be increased when Clonidine is combined with Atenolol.
Atomoxetine	The metabolism of Clonidine can be decreased when combined with Atomoxetine.
Atorvastatin	The metabolism of Clonidine can be decreased when combined with Atorvastatin.
Atracurium	The risk or severity of sedation can be increased when Clonidine is combined with Atracurium.
Atracurium besylate	The risk or severity of sedation can be increased when Clonidine is combined with Atracurium besylate.
Atropine	Atropine may decrease the antihypertensive activities of Clonidine.
Avacopan	The serum concentration of Clonidine can be increased when it is combined with Avacopan.
Avanafil	The serum concentration of Avanafil can be increased when it is combined with Clonidine.
Axitinib	The metabolism of Axitinib can be decreased when combined with Clonidine.
Azathioprine	The metabolism of Azathioprine can be decreased when combined with Clonidine.
Azelastine	Clonidine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Azilsartan medoxomil	The risk or severity of hypotension can be increased when Clonidine is combined with Azilsartan medoxomil.
Azithromycin	The metabolism of Clonidine can be decreased when combined with Azithromycin.
Baclofen	The risk or severity of sedation can be increased when Clonidine is combined with Baclofen.
Balsalazide	The therapeutic efficacy of Clonidine can be decreased when used in combination with Balsalazide.
Beclomethasone dipropionate	The metabolism of Clonidine can be increased when combined with Beclomethasone dipropionate.
Belinostat	The metabolism of Clonidine can be increased when combined with Belinostat.
Belzutifan	The serum concentration of Clonidine can be decreased when it is combined with Belzutifan.
Benazepril	The risk or severity of hypotension can be increased when Clonidine is combined with Benazepril.
Bendamustine	The metabolism of Bendamustine can be decreased when combined with Clonidine.
Bendroflumethiazide	The risk or severity of hypotension can be increased when Clonidine is combined with Bendroflumethiazide.
Benorilate	The therapeutic efficacy of Clonidine can be decreased when used in combination with Benorilate.
Benoxaprofen	The therapeutic efficacy of Clonidine can be decreased when used in combination with Benoxaprofen.
Benperidol	The risk or severity of sedation can be increased when Clonidine is combined with Benperidol.
Benzatropine	The metabolism of Clonidine can be decreased when combined with Benzatropine.
Benzhydrocodone	The risk or severity of hypotension can be increased when Benzhydrocodone is combined with Clonidine.
Benzocaine	The risk or severity of sedation can be increased when Clonidine is combined with Benzocaine.
Benzphetamine	The risk or severity of sedation can be increased when Clonidine is combined with Benzphetamine.
Benzthiazide	The therapeutic efficacy of Clonidine can be increased when used in combination with Benzthiazide.
Benzydamine	The therapeutic efficacy of Clonidine can be decreased when used in combination with Benzydamine.
Benzyl alcohol	The risk or severity of sedation can be increased when Clonidine is combined with Benzyl alcohol.
Benzylpenicilloyl polylysine	Clonidine may decrease effectiveness of Benzylpenicilloyl polylysine as a diagnostic agent.
Bepridil	The risk or severity of hypotension can be increased when Clonidine is combined with Bepridil.
Beractant	Clonidine may increase the bradycardic activities of Beractant.
Berotralstat	The serum concentration of Clonidine can be increased when it is combined with Berotralstat.
Betamethasone	The metabolism of Clonidine can be increased when combined with Betamethasone.
Betamethasone phosphate	The metabolism of Clonidine can be increased when combined with Betamethasone phosphate.
Betaxolol	The risk or severity of hypotension can be increased when Clonidine is combined with Betaxolol.
Bethanidine	The risk or severity of hypotension can be increased when Clonidine is combined with Bethanidine.
Bexarotene	The metabolism of Clonidine can be increased when combined with Bexarotene.
Bicalutamide	The metabolism of Clonidine can be decreased when combined with Bicalutamide.
Bifonazole	The metabolism of Clonidine can be decreased when combined with Bifonazole.
Bimatoprost	Clonidine may increase the hypotensive activities of Bimatoprost.
Bimekizumab	The metabolism of Clonidine can be increased when combined with Bimekizumab.
Binimetinib	The metabolism of Binimetinib can be decreased when combined with Clonidine.
Biperiden	The metabolism of Clonidine can be decreased when combined with Biperiden.
Bisoprolol	The risk or severity of adverse effects can be increased when Bisoprolol is combined with Clonidine.
Boceprevir	The metabolism of Clonidine can be decreased when combined with Boceprevir.
Bortezomib	The metabolism of Clonidine can be decreased when combined with Bortezomib.
Bosentan	The risk or severity of hypotension can be increased when Clonidine is combined with Bosentan.
Bosutinib	The metabolism of Clonidine can be decreased when combined with Bosutinib.
Botulinum toxin type A	The risk or severity of sedation can be increased when Clonidine is combined with Botulinum toxin type A.
Botulinum toxin type B	The risk or severity of sedation can be increased when Clonidine is combined with Botulinum toxin type B.
Brentuximab vedotin	The serum concentration of Clonidine can be increased when it is combined with Brentuximab vedotin.
Bretylium	The risk or severity of hypotension can be increased when Clonidine is combined with Bretylium.
Brexanolone	The risk or severity of sedation can be increased when Clonidine is combined with Brexanolone.
Brexpiprazole	The risk or severity of sedation can be increased when Clonidine is combined with Brexpiprazole.
Brimonidine	Brimonidine may increase the antihypertensive activities of Clonidine.
Brivaracetam	The risk or severity of sedation can be increased when Clonidine is combined with Brivaracetam.
Bromazepam	The risk or severity of sedation can be increased when Clonidine is combined with Bromazepam.
Bromocriptine	The risk or severity of sedation can be increased when Clonidine is combined with Bromocriptine.
Bromotheophylline	The metabolism of Bromotheophylline can be decreased when combined with Clonidine.
Bromperidol	The risk or severity of sedation can be increased when Clonidine is combined with Bromperidol.
Brompheniramine	The risk or severity of sedation can be increased when Clonidine is combined with Brompheniramine.
Buclizine	The risk or severity of Tachycardia can be increased when Buclizine is combined with Clonidine.
Budesonide	The metabolism of Clonidine can be increased when combined with Budesonide.
Bumadizone	The therapeutic efficacy of Clonidine can be decreased when used in combination with Bumadizone.
Bumetanide	The risk or severity of adverse effects can be increased when Clonidine is combined with Bumetanide.
Bupivacaine	The risk or severity of sedation can be increased when Clonidine is combined with Bupivacaine.
Buprenorphine	The risk or severity of sedation can be increased when Clonidine is combined with Buprenorphine.
Bupropion	The risk or severity of sedation can be increased when Clonidine is combined with Bupropion.
Buspirone	The risk or severity of sedation can be increased when Clonidine is combined with Buspirone.
Butabarbital	The risk or severity of sedation can be increased when Clonidine is combined with Butabarbital.
Butalbital	The risk or severity of sedation can be increased when Clonidine is combined with Butalbital.
Butaperazine	The risk or severity of sedation can be increased when Clonidine is combined with Butaperazine.
Butobarbital	The risk or severity of sedation can be increased when Clonidine is combined with Butobarbital.
Butorphanol	The risk or severity of sedation can be increased when Clonidine is combined with Butorphanol.
Butriptyline	The risk or severity of sedation can be increased when Clonidine is combined with Butriptyline.
Butylscopolamine	The risk or severity of Tachycardia can be increased when Clonidine is combined with Butylscopolamine.
Cabazitaxel	The metabolism of Cabazitaxel can be decreased when combined with Clonidine.
Cabergoline	The risk or severity of sedation can be increased when Clonidine is combined with Cabergoline.
Caffeine	The metabolism of Clonidine can be decreased when combined with Caffeine.
Calcitriol	The metabolism of Clonidine can be increased when combined with Calcitriol.
Calfactant	Clonidine may increase the bradycardic activities of Calfactant.
Canagliflozin	The risk or severity of adverse effects can be increased when Clonidine is combined with Canagliflozin.
Canakinumab	The metabolism of Clonidine can be increased when combined with Canakinumab.
Candesartan cilexetil	The risk or severity of hypotension can be increased when Clonidine is combined with Candesartan cilexetil.
Candicidin	The serum concentration of Clonidine can be increased when it is combined with Candicidin.
Cannabidiol	The risk or severity of sedation can be increased when Clonidine is combined with Cannabidiol.
Capmatinib	The serum concentration of Clonidine can be increased when it is combined with Capmatinib.
Capsaicin	The serum concentration of Clonidine can be increased when it is combined with Capsaicin.
Captopril	The risk or severity of hypotension can be increased when Clonidine is combined with Captopril.
Carbamazepine	The risk or severity of sedation can be increased when Clonidine is combined with Carbamazepine.
Carbetocin	The risk or severity of adverse effects can be increased when Clonidine is combined with Carbetocin.
Carbidopa	The risk or severity of hypotension can be increased when Carbidopa is combined with Clonidine.
Carbinoxamine	The risk or severity of sedation can be increased when Clonidine is combined with Carbinoxamine.
Cariprazine	The risk or severity of sedation can be increased when Clonidine is combined with Cariprazine.
Carisoprodol	The risk or severity of sedation can be increased when Clonidine is combined with Carisoprodol.
Carmustine	The metabolism of Clonidine can be decreased when combined with Carmustine.
Carprofen	The therapeutic efficacy of Clonidine can be decreased when used in combination with Carprofen.
Carteolol	Carteolol may increase the hypotensive activities of Clonidine.
Carvedilol	The risk or severity of hypotension can be increased when Clonidine is combined with Carvedilol.
Cefradine	The metabolism of Clonidine can be increased when combined with Cefradine.
Celecoxib	The metabolism of Clonidine can be decreased when combined with Celecoxib.
Celiprolol	The risk or severity of hypotension can be increased when Clonidine is combined with Celiprolol.
Cenobamate	The serum concentration of Clonidine can be decreased when it is combined with Cenobamate.
Cephalexin	The metabolism of Clonidine can be decreased when combined with Cephalexin.
Ceritinib	Clonidine may increase the bradycardic activities of Ceritinib.
Cerivastatin	The metabolism of Clonidine can be increased when combined with Cerivastatin.
Certolizumab pegol	The metabolism of Clonidine can be increased when combined with Certolizumab pegol.
Cetirizine	The risk or severity of sedation can be increased when Clonidine is combined with Cetirizine.
Cevimeline	The metabolism of Clonidine can be decreased when combined with Cevimeline.
Chloral hydrate	The risk or severity of sedation can be increased when Clonidine is combined with Chloral hydrate.
Chloramphenicol	The serum concentration of Clonidine can be increased when it is combined with Chloramphenicol.
Chlordiazepoxide	The risk or severity of sedation can be increased when Clonidine is combined with Chlordiazepoxide.
Chlormezanone	The risk or severity of sedation can be increased when Clonidine is combined with Chlormezanone.
Chloroform	The therapeutic efficacy of Chloroform can be increased when used in combination with Clonidine.
Chloroprocaine	The risk or severity of sedation can be increased when Clonidine is combined with Chloroprocaine.
Chloroquine	The metabolism of Clonidine can be decreased when combined with Chloroquine.
Chlorothiazide	The risk or severity of hypotension can be increased when Clonidine is combined with Chlorothiazide.
Chlorpheniramine	The risk or severity of sedation can be increased when Clonidine is combined with Chlorpheniramine.
Chlorpromazine	The risk or severity of sedation can be increased when Clonidine is combined with Chlorpromazine.
Chlorprothixene	The risk or severity of sedation can be increased when Clonidine is combined with Chlorprothixene.
Chlorzoxazone	The risk or severity of sedation can be increased when Clonidine is combined with Chlorzoxazone.
Cholecalciferol	The metabolism of Clonidine can be decreased when combined with Cholecalciferol.
Choline magnesium trisalicylate	The therapeutic efficacy of Clonidine can be decreased when used in combination with Choline magnesium trisalicylate.
Ciclesonide	The metabolism of Clonidine can be decreased when combined with Ciclesonide.
Cilazapril	The risk or severity of hypotension can be increased when Clonidine is combined with Cilazapril.
Cilostazol	The metabolism of Clonidine can be decreased when combined with Cilostazol.
Cimetidine	The metabolism of Clonidine can be decreased when combined with Cimetidine.
Cinacalcet	The metabolism of Clonidine can be decreased when combined with Cinacalcet.
Cinchocaine	The risk or severity of sedation can be increased when Clonidine is combined with Cinchocaine.
Cinnarizine	Clonidine may increase the atrioventricular blocking (AV block) activities of Cinnarizine.
Cinoxacin	The metabolism of Clonidine can be decreased when combined with Cinoxacin.
Ciprofloxacin	The metabolism of Clonidine can be decreased when combined with Ciprofloxacin.
Cisapride	The risk or severity of sedation can be increased when Clonidine is combined with Cisapride.
Cisatracurium	The risk or severity of sedation can be increased when Clonidine is combined with Cisatracurium.
Citalopram	The risk or severity of sedation can be increased when Clonidine is combined with Citalopram.
Clarithromycin	The metabolism of Clonidine can be decreased when combined with Clarithromycin.
Clemastine	The risk or severity of sedation can be increased when Clonidine is combined with Clemastine.
Clenbuterol	Clenbuterol may decrease the antihypertensive activities of Clonidine.
Clevidipine	Clonidine may increase the atrioventricular blocking (AV block) activities of Clevidipine.
Clidinium	The risk or severity of sedation can be increased when Clonidine is combined with Clidinium.
Clindamycin	The metabolism of Clonidine can be decreased when combined with Clindamycin.
Clobazam	The risk or severity of sedation can be increased when Clonidine is combined with Clobazam.
Clobetasol propionate	The metabolism of Clonidine can be increased when combined with Clobetasol propionate.
Clofarabine	The risk or severity of adverse effects can be increased when Clonidine is combined with Clofarabine.
Clofazimine	The serum concentration of Clonidine can be increased when it is combined with Clofazimine.
Clofibrate	The metabolism of Clonidine can be increased when combined with Clofibrate.
Clomipramine	The risk or severity of sedation can be increased when Clonidine is combined with Clomipramine.
Clonazepam	The risk or severity of sedation can be increased when Clonidine is combined with Clonazepam.
Clopidogrel	The metabolism of Clonidine can be decreased when combined with Clopidogrel.
Clorazepic acid	The risk or severity of sedation can be increased when Clonidine is combined with Clorazepic acid.
Clothiapine	The risk or severity of sedation can be increased when Clonidine is combined with Clothiapine.
Clotiazepam	The risk or severity of sedation can be increased when Clonidine is combined with Clotiazepam.
Clozapine	The risk or severity of sedation can be increased when Clonidine is combined with Clozapine.
Cobicistat	The metabolism of Clonidine can be decreased when combined with Cobicistat.
Cobimetinib	The metabolism of Clonidine can be decreased when combined with Cobimetinib.
Cocaine	The metabolism of Clonidine can be decreased when combined with Cocaine.
Codeine	The risk or severity of sedation can be increased when Clonidine is combined with Codeine.
Conivaptan	The metabolism of Clonidine can be decreased when combined with Conivaptan.
Conjugated estrogens	The metabolism of Clonidine can be decreased when combined with Conjugated estrogens.
Copanlisib	The metabolism of Copanlisib can be decreased when combined with Clonidine.
Corticotropin	The metabolism of Clonidine can be increased when combined with Corticotropin.
Cortisone acetate	The metabolism of Clonidine can be increased when combined with Cortisone acetate.
Crizotinib	The metabolism of Clonidine can be decreased when combined with Crizotinib.
Cryptenamine	The risk or severity of hypotension can be increased when Clonidine is combined with Cryptenamine.
Curcumin	The metabolism of Clonidine can be decreased when combined with Curcumin.
Cyclandelate	Clonidine may increase the atrioventricular blocking (AV block) activities of Cyclandelate.
Cyclizine	The risk or severity of sedation can be increased when Clonidine is combined with Cyclizine.
Cyclobenzaprine	The risk or severity of sedation can be increased when Clonidine is combined with Cyclobenzaprine.
Cyclopenthiazide	The risk or severity of hypotension can be increased when Clonidine is combined with Cyclopenthiazide.
Cyclophosphamide	The metabolism of Clonidine can be increased when combined with Cyclophosphamide.
Cyclosporine	The metabolism of Clonidine can be decreased when combined with Cyclosporine.
Cyclothiazide	The risk or severity of hypotension can be increased when Clonidine is combined with Cyclothiazide.
Cycrimine	The risk or severity of Tachycardia can be increased when Clonidine is combined with Cycrimine.
Cyproheptadine	The risk or severity of sedation can be increased when Clonidine is combined with Cyproheptadine.
Cyproterone acetate	The risk or severity of sedation can be increased when Cyproterone acetate is combined with Clonidine.
Dabrafenib	The serum concentration of Clonidine can be decreased when it is combined with Dabrafenib.
Dacarbazine	The metabolism of Dacarbazine can be decreased when combined with Clonidine.
Daclatasvir	The metabolism of Clonidine can be decreased when combined with Daclatasvir.
Dacomitinib	The metabolism of Clonidine can be decreased when combined with Dacomitinib.
Dalfopristin	The metabolism of Clonidine can be decreased when combined with Dalfopristin.
Danazol	The metabolism of Clonidine can be decreased when combined with Danazol.
Dantrolene	The risk or severity of sedation can be increased when Clonidine is combined with Dantrolene.
Dapagliflozin	The risk or severity of adverse effects can be increased when Clonidine is combined with Dapagliflozin.
Dapsone	The metabolism of Clonidine can be decreased when combined with Dapsone.
Daridorexant	The risk or severity of sedation can be increased when Clonidine is combined with Daridorexant.
Darifenacin	The metabolism of Clonidine can be decreased when combined with Darifenacin.
Darunavir	The serum concentration of Clonidine can be increased when it is combined with Darunavir.
Dasabuvir	The metabolism of Clonidine can be decreased when combined with Dasabuvir.
Dasatinib	The metabolism of Clonidine can be decreased when combined with Dasatinib.
Dasiglucagon	The risk or severity of hypotension can be increased when Clonidine is combined with Dasiglucagon.
Daunorubicin	The serum concentration of Clonidine can be increased when it is combined with Daunorubicin.
Debrisoquine	The risk or severity of hypotension can be increased when Clonidine is combined with Debrisoquine.
Decamethonium	The risk or severity of sedation can be increased when Clonidine is combined with Decamethonium.
Deferasirox	The serum concentration of Clonidine can be increased when it is combined with Deferasirox.
Deflazacort	The metabolism of Clonidine can be increased when combined with Deflazacort.
Delavirdine	The metabolism of Clonidine can be decreased when combined with Delavirdine.
Deserpidine	The risk or severity of hypotension can be increased when Clonidine is combined with Deserpidine.
Desflurane	The risk or severity of sedation can be increased when Clonidine is combined with Desflurane.
Desipramine	The risk or severity of sedation can be increased when Clonidine is combined with Desipramine.
Deslanoside	Clonidine may increase the atrioventricular blocking (AV block) activities of Deslanoside.
Desloratadine	The risk or severity of sedation can be increased when Clonidine is combined with Desloratadine.
Desmopressin	Desmopressin may decrease the antihypertensive activities of Clonidine.
Desogestrel	The risk or severity of sedation can be increased when Desogestrel is combined with Clonidine.
Desvenlafaxine	The risk or severity of sedation can be increased when Clonidine is combined with Desvenlafaxine.
Deutetrabenazine	The metabolism of Clonidine can be decreased when combined with Deutetrabenazine.
Dexamethasone	The metabolism of Clonidine can be increased when combined with Dexamethasone.
Dexamethasone acetate	The metabolism of Clonidine can be increased when combined with Dexamethasone acetate.
Dexbrompheniramine	The risk or severity of sedation can be increased when Clonidine is combined with Dexbrompheniramine.
Dexchlorpheniramine maleate	The metabolism of Clonidine can be decreased when combined with Dexchlorpheniramine maleate.
Dexfenfluramine	The metabolism of Clonidine can be decreased when combined with Dexfenfluramine.
Dexibuprofen	The therapeutic efficacy of Clonidine can be decreased when used in combination with Dexibuprofen.
Dexketoprofen	The therapeutic efficacy of Clonidine can be decreased when used in combination with Dexketoprofen.
Dexmedetomidine	The risk or severity of sedation can be increased when Clonidine is combined with Dexmedetomidine.
Dexmethylphenidate	The risk or severity of sedation can be increased when Clonidine is combined with Dexmethylphenidate.
Dextroamphetamine	The metabolism of Clonidine can be decreased when combined with Dextroamphetamine.
Dextromethorphan	The risk or severity of sedation can be increased when Clonidine is combined with Dextromethorphan.
Dextropropoxyphene	The risk or severity of sedation can be increased when Clonidine is combined with Dextropropoxyphene.
Dezocine	The risk or severity of sedation can be increased when Clonidine is combined with Dezocine.
Diacerein	The metabolism of Clonidine can be decreased when combined with Diacerein.
Diamorphine	The risk or severity of sedation can be increased when Clonidine is combined with Diamorphine.
Diazepam	The risk or severity of sedation can be increased when Clonidine is combined with Diazepam.
Diazoxide	Diazoxide may increase the hypotensive activities of Clonidine.
Dibenzepin	The risk or severity of sedation can be increased when Clonidine is combined with Dibenzepin.
Dichloralphenazone	The risk or severity of sedation can be increased when Clonidine is combined with Dichloralphenazone.
Diclofenac	The therapeutic efficacy of Clonidine can be decreased when used in combination with Diclofenac.
Diclofenamide	The risk or severity of adverse effects can be increased when Clonidine is combined with Diclofenamide.
Dicloxacillin	The metabolism of Clonidine can be increased when combined with Dicloxacillin.
Dicyclomine	The risk or severity of Tachycardia can be increased when Clonidine is combined with Dicyclomine.
Dienogest	The risk or severity of sedation can be increased when Dienogest is combined with Clonidine.
Diethylpropion	The risk or severity of sedation can be increased when Clonidine is combined with Diethylpropion.
Diethylstilbestrol	The serum concentration of Clonidine can be increased when it is combined with Diethylstilbestrol.
Difenoxin	The risk or severity of sedation can be increased when Clonidine is combined with Difenoxin.
Diflunisal	The therapeutic efficacy of Clonidine can be decreased when used in combination with Diflunisal.
Difluocortolone	The metabolism of Clonidine can be increased when combined with Difluocortolone.
Digitoxin	Clonidine may increase the atrioventricular blocking (AV block) activities of Digitoxin.
Digoxin	Clonidine may increase the atrioventricular blocking (AV block) activities of Digoxin.
Dihydralazine	The risk or severity of hypotension can be increased when Clonidine is combined with Dihydralazine.
Dihydrocodeine	The risk or severity of sedation can be increased when Clonidine is combined with Dihydrocodeine.
Dihydroergocornine	Dihydroergocornine may increase the hypertensive and vasoconstricting activities of Clonidine.
Dihydroergocristine	Dihydroergocristine may increase the hypertensive and vasoconstricting activities of Clonidine.
Dihydroergotamine	The risk or severity of sedation can be increased when Clonidine is combined with Dihydroergotamine.
Diltiazem	Diltiazem may increase the atrioventricular blocking (AV block) activities of Clonidine.
Dimenhydrinate	The risk or severity of sedation can be increased when Clonidine is combined with Dimenhydrinate.
Dimethyl sulfoxide	The serum concentration of Clonidine can be increased when it is combined with Dimethyl sulfoxide.
Dimetindene	The risk or severity of Tachycardia can be increased when Clonidine is combined with Dimetindene.
Dinutuximab	The risk or severity of adverse effects can be increased when Clonidine is combined with Dinutuximab.
Diosmin	The serum concentration of Clonidine can be increased when it is combined with Diosmin.
Diphemanil	The risk or severity of Tachycardia can be increased when Clonidine is combined with Diphemanil.
Diphenhydramine	The risk or severity of sedation can be increased when Clonidine is combined with Diphenhydramine.
Diphenidol	The risk or severity of Tachycardia can be increased when Clonidine is combined with Diphenidol.
Diphenoxylate	The risk or severity of sedation can be increased when Clonidine is combined with Diphenoxylate.
Dipyridamole	Dipyridamole may increase the antihypertensive activities of Clonidine.
Disopyramide	The metabolism of Clonidine can be decreased when combined with Disopyramide.
Disulfiram	The metabolism of Clonidine can be decreased when combined with Disulfiram.
DL-Methylephedrine	DL-Methylephedrine may decrease the antihypertensive activities of Clonidine.
Dobutamine	Dobutamine may decrease the antihypertensive activities of Clonidine.
Docetaxel	The serum concentration of Clonidine can be increased when it is combined with Docetaxel.
Dolasetron	The risk or severity of sedation can be increased when Clonidine is combined with Dolasetron.
Domperidone	The metabolism of Clonidine can be decreased when combined with Domperidone.
Donepezil	The risk or severity of sedation can be increased when Clonidine is combined with Donepezil.
Dopamine	Dopamine may decrease the antihypertensive activities of Clonidine.
Dopexamine	Dopexamine may decrease the antihypertensive activities of Clonidine.
Doravirine	The metabolism of Clonidine can be decreased when combined with Doravirine.
Dorzolamide	Clonidine may increase the hypotensive activities of Dorzolamide.
Dosulepin	The risk or severity of sedation can be increased when Clonidine is combined with Dosulepin.
Doxacurium	The risk or severity of sedation can be increased when Clonidine is combined with Doxacurium.
Doxapram	Doxapram may decrease the antihypertensive activities of Clonidine.
Doxazosin	The risk or severity of hypotension can be increased when Clonidine is combined with Doxazosin.
Doxepin	The risk or severity of sedation can be increased when Clonidine is combined with Doxepin.
Doxorubicin	The serum concentration of Clonidine can be increased when it is combined with Doxorubicin.
Doxylamine	The risk or severity of sedation can be increased when Clonidine is combined with Doxylamine.
Dronabinol	The risk or severity of sedation can be increased when Clonidine is combined with Dronabinol.
Dronedarone	The serum concentration of Clonidine can be increased when it is combined with Dronedarone.
Droperidol	The risk or severity of sedation can be increased when Clonidine is combined with Droperidol.
Drospirenone	The risk or severity of sedation can be increased when Drospirenone is combined with Clonidine.
Droxidopa	Droxidopa may decrease the antihypertensive activities of Clonidine.
Duloxetine	The risk or severity of sedation can be increased when Clonidine is combined with Duloxetine.
Dutasteride	The metabolism of Clonidine can be decreased when combined with Dutasteride.
Duvelisib	The metabolism of Clonidine can be decreased when combined with Duvelisib.
Dyclonine	The risk or severity of sedation can be increased when Clonidine is combined with Dyclonine.
Ebastine	The metabolism of Clonidine can be decreased when combined with Ebastine.
Echinacea	The metabolism of Clonidine can be increased when combined with Echinacea.
Efavirenz	The risk or severity of sedation can be increased when Clonidine is combined with Efavirenz.
Elagolix	The metabolism of Clonidine can be decreased when combined with Elagolix.
Elbasvir	The metabolism of Clonidine can be decreased when combined with Elbasvir.
Eletriptan	The risk or severity of sedation can be increased when Clonidine is combined with Eletriptan.
Elexacaftor	The metabolism of Clonidine can be decreased when combined with Elexacaftor.
Eliglustat	The metabolism of Clonidine can be decreased when combined with Eliglustat.
Eltrombopag	The metabolism of Eltrombopag can be decreased when combined with Clonidine.
Eluxadoline	The risk or severity of hypotension can be increased when Eluxadoline is combined with Clonidine.
Elvitegravir	The metabolism of Clonidine can be decreased when combined with Elvitegravir.
Emapalumab	The metabolism of Clonidine can be increased when combined with Emapalumab.
Empagliflozin	The risk or severity of adverse effects can be increased when Clonidine is combined with Empagliflozin.
Enalapril	The risk or severity of hypotension can be increased when Clonidine is combined with Enalapril.
Enalaprilat	The risk or severity of hypotension can be increased when Clonidine is combined with Enalaprilat.
Enasidenib	The metabolism of Clonidine can be increased when combined with Enasidenib.
Encainide	The metabolism of Clonidine can be decreased when combined with Encainide.
Encorafenib	The metabolism of Clonidine can be increased when combined with Encorafenib.
Enflurane	The risk or severity of sedation can be increased when Clonidine is combined with Enflurane.
Enoxacin	The metabolism of Clonidine can be decreased when combined with Enoxacin.
Entacapone	The risk or severity of sedation can be increased when Clonidine is combined with Entacapone.
Entecavir	The metabolism of Clonidine can be decreased when combined with Entecavir.
Enzalutamide	The serum concentration of Clonidine can be decreased when it is combined with Enzalutamide.
Epcoritamab	The serum concentration of Clonidine can be increased when it is combined with Epcoritamab.
Ephedrine	Ephedrine may decrease the antihypertensive activities of Clonidine.
Epinastine	The risk or severity of sedation can be increased when Clonidine is combined with Epinastine.
Epinephrine	The serum concentration of Clonidine can be increased when it is combined with Epinephrine.
Eplerenone	The risk or severity of hypotension can be increased when Clonidine is combined with Eplerenone.
Epoprostenol	The risk or severity of hypotension can be increased when Clonidine is combined with Epoprostenol.
Eprosartan	The risk or severity of hypotension can be increased when Clonidine is combined with Eprosartan.
Erdafitinib	The serum concentration of Clonidine can be increased when it is combined with Erdafitinib.
Ergoloid mesylate	The risk or severity of sedation can be increased when Clonidine is combined with Ergoloid mesylate.
Ergometrine	The risk or severity of sedation can be increased when Clonidine is combined with Ergometrine.
Ergotamine	The risk or severity of sedation can be increased when Clonidine is combined with Ergotamine.
Erlotinib	The serum concentration of Clonidine can be increased when it is combined with Erlotinib.
Erythromycin	The serum concentration of Clonidine can be increased when it is combined with Erythromycin.
Escitalopram	The risk or severity of sedation can be increased when Clonidine is combined with Escitalopram.
Esketamine	The risk or severity of sedation can be increased when Clonidine is combined with Esketamine.
Eslicarbazepine	The risk or severity of sedation can be increased when Clonidine is combined with Eslicarbazepine.
Eslicarbazepine acetate	The risk or severity of sedation can be increased when Clonidine is combined with Eslicarbazepine acetate.
Esmolol	The risk or severity of hypotension can be increased when Clonidine is combined with Esmolol.
Estazolam	The risk or severity of sedation can be increased when Clonidine is combined with Estazolam.
Estetrol	The risk or severity of sedation can be increased when Estetrol is combined with Clonidine.
Estradiol	The risk or severity of sedation can be increased when Estradiol is combined with Clonidine.
Estradiol acetate	The metabolism of Clonidine can be increased when combined with Estradiol acetate.
Estradiol benzoate	The metabolism of Clonidine can be increased when combined with Estradiol benzoate.
Estradiol cypionate	The metabolism of Clonidine can be increased when combined with Estradiol cypionate.
Estradiol dienanthate	The metabolism of Clonidine can be increased when combined with Estradiol dienanthate.
Estradiol valerate	The metabolism of Clonidine can be increased when combined with Estradiol valerate.
Estrone sulfate	The metabolism of Clonidine can be decreased when combined with Estrone sulfate.
Eszopiclone	The risk or severity of sedation can be increased when Clonidine is combined with Eszopiclone.
Etacrynic acid	The risk or severity of adverse effects can be increased when Clonidine is combined with Etacrynic acid.
Etafedrine	Etafedrine may decrease the antihypertensive activities of Clonidine.
Etanercept	The metabolism of Clonidine can be increased when combined with Etanercept.
Ethambutol	The metabolism of Clonidine can be decreased when combined with Ethambutol.
Ethanol	Ethanol may increase the central nervous system depressant (CNS depressant) activities of Clonidine.
Ethchlorvynol	The risk or severity of sedation can be increased when Clonidine is combined with Ethchlorvynol.
Ethinylestradiol	The risk or severity of sedation can be increased when Ethinylestradiol is combined with Clonidine.
Ethosuximide	The risk or severity of sedation can be increased when Clonidine is combined with Ethosuximide.
Ethotoin	The risk or severity of sedation can be increased when Clonidine is combined with Ethotoin.
Ethynodiol diacetate	The risk or severity of sedation can be increased when Ethynodiol diacetate is combined with Clonidine.
Etilefrine	Etilefrine may decrease the antihypertensive activities of Clonidine.
Etodolac	The therapeutic efficacy of Clonidine can be decreased when used in combination with Etodolac.
Etomidate	The risk or severity of sedation can be increased when Clonidine is combined with Etomidate.
Etoposide	The metabolism of Etoposide can be decreased when combined with Clonidine.
Etoricoxib	The serum concentration of Clonidine can be increased when it is combined with Etoricoxib.
Etravirine	The metabolism of Clonidine can be increased when combined with Etravirine.
Everolimus	The metabolism of Clonidine can be decreased when combined with Everolimus.
Ezogabine	The risk or severity of sedation can be increased when Clonidine is combined with Ezogabine.
Famotidine	The metabolism of Clonidine can be decreased when combined with Famotidine.
Fedratinib	The serum concentration of Clonidine can be increased when it is combined with Fedratinib.
Felbamate	The risk or severity of sedation can be increased when Clonidine is combined with Felbamate.
Felodipine	The risk or severity of hypotension can be increased when Clonidine is combined with Felodipine.
Fenbufen	The therapeutic efficacy of Clonidine can be decreased when used in combination with Fenbufen.
Fenfluramine	The risk or severity of sedation can be increased when Clonidine is combined with Fenfluramine.
Fenofibrate	The metabolism of Clonidine can be decreased when combined with Fenofibrate.
Fenoldopam	The risk or severity of hypotension can be increased when Clonidine is combined with Fenoldopam.
Fenoprofen	The therapeutic efficacy of Clonidine can be decreased when used in combination with Fenoprofen.
Fenoterol	Fenoterol may decrease the antihypertensive activities of Clonidine.
Fentanyl	The risk or severity of sedation can be increased when Clonidine is combined with Fentanyl.
Fesoterodine	The metabolism of Clonidine can be decreased when combined with Fesoterodine.
Fexinidazole	The risk or severity of adverse effects can be increased when Clonidine is combined with Fexinidazole.
Fezolinetant	The metabolism of Fezolinetant can be decreased when combined with Clonidine.
Filgotinib	The serum concentration of Clonidine can be increased when it is combined with Filgotinib.
Finasteride	The metabolism of Clonidine can be decreased when combined with Finasteride.
Fingolimod	Clonidine may increase the bradycardic activities of Fingolimod.
Flavoxate	The risk or severity of Tachycardia can be increased when Clonidine is combined with Flavoxate.
Flecainide	The metabolism of Clonidine can be decreased when combined with Flecainide.
Flibanserin	The risk or severity of sedation can be increased when Clonidine is combined with Flibanserin.
Floctafenine	The therapeutic efficacy of Clonidine can be decreased when used in combination with Floctafenine.
Flucloxacillin	The metabolism of Clonidine can be increased when combined with Flucloxacillin.
Fluconazole	The metabolism of Clonidine can be decreased when combined with Fluconazole.
Flunarizine	The risk or severity of sedation can be increased when Clonidine is combined with Flunarizine.
Flunisolide	The metabolism of Clonidine can be increased when combined with Flunisolide.
Flunitrazepam	The risk or severity of sedation can be increased when Clonidine is combined with Flunitrazepam.
Fluocinolone acetonide	The metabolism of Clonidine can be increased when combined with Fluocinolone acetonide.
Fluocinonide	The metabolism of Clonidine can be increased when combined with Fluocinonide.
Fluocortolone	The metabolism of Clonidine can be increased when combined with Fluocortolone.
Fluorouracil	The metabolism of Clonidine can be decreased when combined with Fluorouracil.
Fluoxetine	The risk or severity of sedation can be increased when Clonidine is combined with Fluoxetine.
Flupentixol	The risk or severity of sedation can be increased when Clonidine is combined with Flupentixol.
Fluphenazine	The risk or severity of adverse effects can be increased when Fluphenazine is combined with Clonidine.
Flurazepam	The risk or severity of sedation can be increased when Clonidine is combined with Flurazepam.
Flurbiprofen	The therapeutic efficacy of Clonidine can be decreased when used in combination with Flurbiprofen.
Fluspirilene	The risk or severity of sedation can be increased when Clonidine is combined with Fluspirilene.
Flutamide	The metabolism of Clonidine can be decreased when combined with Flutamide.
Fluticasone	The metabolism of Clonidine can be increased when combined with Fluticasone.
Fluticasone furoate	The metabolism of Clonidine can be decreased when combined with Fluticasone furoate.
Fluticasone propionate	The risk or severity of sedation can be increased when Clonidine is combined with Fluticasone propionate.
Fluvastatin	The metabolism of Clonidine can be decreased when combined with Fluvastatin.
Fluvoxamine	The risk or severity of sedation can be increased when Clonidine is combined with Fluvoxamine.
Formestane	The metabolism of Clonidine can be increased when combined with Formestane.
Formoterol	Clonidine may increase the sympathomimetic activities of Formoterol.
Fosamprenavir	The serum concentration of Clonidine can be increased when it is combined with Fosamprenavir.
Fosaprepitant	The metabolism of Clonidine can be increased when combined with Fosaprepitant.
Fosinopril	The risk or severity of hypotension can be increased when Clonidine is combined with Fosinopril.
Fosnetupitant	The metabolism of Clonidine can be decreased when combined with Fosnetupitant.
Fosphenytoin	The risk or severity of sedation can be increased when Clonidine is combined with Fosphenytoin.
Fospropofol	The risk or severity of sedation can be increased when Clonidine is combined with Fospropofol.
Fostamatinib	The serum concentration of Clonidine can be increased when it is combined with Fostamatinib.
Frovatriptan	The risk or severity of sedation can be increased when Clonidine is combined with Frovatriptan.
Fruquintinib	The metabolism of Clonidine can be decreased when combined with Fruquintinib.
Furosemide	The risk or severity of hypotension can be increased when Clonidine is combined with Furosemide.
Fusidic acid	The metabolism of Clonidine can be decreased when combined with Fusidic acid.
Gabapentin	The risk or severity of sedation can be increased when Clonidine is combined with Gabapentin.
Gabapentin enacarbil	The risk or severity of sedation can be increased when Clonidine is combined with Gabapentin enacarbil.
Galantamine	The metabolism of Clonidine can be decreased when combined with Galantamine.
Gallamine triethiodide	The risk or severity of sedation can be increased when Clonidine is combined with Gallamine triethiodide.
gamma-Hydroxybutyric acid	The risk or severity of sedation can be increased when Clonidine is combined with gamma-Hydroxybutyric acid.
Ganaxolone	The risk or severity of sedation can be increased when Clonidine is combined with Ganaxolone.
Gatifloxacin	The metabolism of Clonidine can be decreased when combined with Gatifloxacin.
Gefitinib	The metabolism of Clonidine can be decreased when combined with Gefitinib.
Gemfibrozil	The metabolism of Clonidine can be decreased when combined with Gemfibrozil.
Gemifloxacin	The metabolism of Clonidine can be decreased when combined with Gemifloxacin.
Gepirone	The risk or severity of sedation can be increased when Clonidine is combined with Gepirone.
Gestrinone	The risk or severity of sedation can be increased when Gestrinone is combined with Clonidine.
Gilteritinib	The metabolism of Clonidine can be decreased when combined with Gilteritinib.
Ginkgo biloba	The metabolism of Clonidine can be decreased when combined with Ginkgo biloba.
Givinostat	The serum concentration of Clonidine can be increased when it is combined with Givinostat.
Givosiran	The serum concentration of Clonidine can be increased when it is combined with Givosiran.
Glecaprevir	The metabolism of Clonidine can be decreased when combined with Glecaprevir.
Glofitamab	The serum concentration of Clonidine can be increased when it is combined with Glofitamab.
Glutethimide	The risk or severity of sedation can be increased when Clonidine is combined with Glutethimide.
Glyburide	The metabolism of Clonidine can be decreased when combined with Glyburide.
Glycerol phenylbutyrate	The metabolism of Clonidine can be increased when combined with Glycerol phenylbutyrate.
Glycol salicylate	The therapeutic efficacy of Clonidine can be decreased when used in combination with Glycol salicylate.
Glycopyrronium	The risk or severity of Tachycardia can be increased when Clonidine is combined with Glycopyrronium.
Golimumab	The metabolism of Clonidine can be increased when combined with Golimumab.
Granisetron	The risk or severity of sedation can be increased when Clonidine is combined with Granisetron.
Grapefruit	The serum concentration of Clonidine can be increased when it is combined with Grapefruit.
Grepafloxacin	The metabolism of Clonidine can be decreased when combined with Grepafloxacin.
Griseofulvin	The metabolism of Clonidine can be increased when combined with Griseofulvin.
Guanabenz	The risk or severity of hypotension can be increased when Clonidine is combined with Guanabenz.
Guanadrel	The risk or severity of hypotension can be increased when Clonidine is combined with Guanadrel.
Guanethidine	The risk or severity of hypotension can be increased when Clonidine is combined with Guanethidine.
Guanfacine	The risk or severity of sedation can be increased when Clonidine is combined with Guanfacine.
Guanoxan	The risk or severity of hypotension can be increased when Clonidine is combined with Guanoxan.
Halazepam	The risk or severity of sedation can be increased when Clonidine is combined with Halazepam.
Halofantrine	The metabolism of Clonidine can be decreased when combined with Halofantrine.
Haloperidol	The risk or severity of sedation can be increased when Clonidine is combined with Haloperidol.
Halothane	The risk or severity of sedation can be increased when Clonidine is combined with Halothane.
Hexafluronium	The risk or severity of sedation can be increased when Clonidine is combined with Hexafluronium.
Hexocyclium	The risk or severity of Tachycardia can be increased when Clonidine is combined with Hexocyclium.
Homatropine methylbromide	The risk or severity of Tachycardia can be increased when Clonidine is combined with Homatropine methylbromide.
Hyaluronidase	The risk or severity of adverse effects can be increased when Hyaluronidase is combined with Clonidine.
Hyaluronidase (human recombinant)	The risk or severity of adverse effects can be increased when Hyaluronidase (human recombinant) is combined with Clonidine.
Hyaluronidase (ovine)	The risk or severity of adverse effects can be increased when Hyaluronidase (ovine) is combined with Clonidine.
Hydralazine	The risk or severity of hypotension can be increased when Clonidine is combined with Hydralazine.
Hydrochlorothiazide	The risk or severity of hypotension can be increased when Clonidine is combined with Hydrochlorothiazide.
Hydrocodone	The risk or severity of sedation can be increased when Clonidine is combined with Hydrocodone.
Hydrocortamate	The metabolism of Clonidine can be increased when combined with Hydrocortamate.
Hydrocortisone	The metabolism of Clonidine can be increased when combined with Hydrocortisone.
Hydrocortisone acetate	The metabolism of Clonidine can be increased when combined with Hydrocortisone acetate.
Hydrocortisone butyrate	The metabolism of Clonidine can be increased when combined with Hydrocortisone butyrate.
Hydrocortisone cypionate	The metabolism of Clonidine can be decreased when combined with Hydrocortisone cypionate.
Hydrocortisone phosphate	The metabolism of Clonidine can be decreased when combined with Hydrocortisone phosphate.
Hydrocortisone succinate	The metabolism of Clonidine can be increased when combined with Hydrocortisone succinate.
Hydroflumethiazide	The risk or severity of hypotension can be increased when Clonidine is combined with Hydroflumethiazide.
Hydromorphone	The risk or severity of sedation can be increased when Clonidine is combined with Hydromorphone.
Hydroxychloroquine	The metabolism of Clonidine can be decreased when combined with Hydroxychloroquine.
Hydroxyprogesterone caproate	The metabolism of Clonidine can be decreased when combined with Hydroxyprogesterone caproate.
Hydroxyzine	The risk or severity of sedation can be increased when Clonidine is combined with Hydroxyzine.
Hyoscyamine	The risk or severity of Tachycardia can be increased when Hyoscyamine is combined with Clonidine.
Ibrutinib	The metabolism of Clonidine can be decreased when combined with Ibrutinib.
Ibuprofen	The therapeutic efficacy of Clonidine can be decreased when used in combination with Ibuprofen.
Icosapent	The therapeutic efficacy of Clonidine can be decreased when used in combination with Icosapent.
Idarubicin	The metabolism of Clonidine can be decreased when combined with Idarubicin.
Idelalisib	The metabolism of Clonidine can be decreased when combined with Idelalisib.
Ifosfamide	The metabolism of Clonidine can be increased when combined with Ifosfamide.
Iloperidone	The risk or severity of sedation can be increased when Clonidine is combined with Iloperidone.
Iloprost	Iloprost may increase the hypotensive activities of Clonidine.
Imatinib	The serum concentration of Clonidine can be increased when it is combined with Imatinib.
Imipramine	The risk or severity of sedation can be increased when Clonidine is combined with Imipramine.
Indacaterol	Indacaterol may decrease the antihypertensive activities of Clonidine.
Indapamide	The risk or severity of hypotension can be increased when Clonidine is combined with Indapamide.
Indinavir	The metabolism of Clonidine can be decreased when combined with Indinavir.
Indomethacin	The therapeutic efficacy of Clonidine can be decreased when used in combination with Indomethacin.
Indoramin	The risk or severity of hypotension can be increased when Clonidine is combined with Indoramin.
Infigratinib	The metabolism of Clonidine can be decreased when combined with Infigratinib.
Infliximab	The metabolism of Clonidine can be increased when combined with Infliximab.
Insulin aspart	The therapeutic efficacy of Insulin aspart can be increased when used in combination with Clonidine.
Insulin beef	The therapeutic efficacy of Insulin beef can be increased when used in combination with Clonidine.
Insulin degludec	The therapeutic efficacy of Insulin degludec can be increased when used in combination with Clonidine.
Insulin detemir	The therapeutic efficacy of Insulin detemir can be increased when used in combination with Clonidine.
Insulin glargine	The therapeutic efficacy of Insulin glargine can be increased when used in combination with Clonidine.
Insulin glulisine	The therapeutic efficacy of Insulin glulisine can be increased when used in combination with Clonidine.
Insulin human	The therapeutic efficacy of Insulin human can be increased when used in combination with Clonidine.
Insulin lispro	The therapeutic efficacy of Insulin lispro can be increased when used in combination with Clonidine.
Insulin pork	The therapeutic efficacy of Insulin pork can be increased when used in combination with Clonidine.
Interferon alfa-2a	The metabolism of Clonidine can be decreased when combined with Interferon alfa-2a.
Interferon alfa-2b	The metabolism of Clonidine can be decreased when combined with Interferon alfa-2b.
Interferon alfa-n1	The metabolism of Clonidine can be decreased when combined with Interferon alfa-n1.
Interferon alfa-n3	The metabolism of Clonidine can be decreased when combined with Interferon alfa-n3.
Interferon alfacon-1	The metabolism of Clonidine can be decreased when combined with Interferon alfacon-1.
Interferon beta-1a	The metabolism of Clonidine can be decreased when combined with Interferon beta-1a.
Interferon beta-1b	The metabolism of Clonidine can be decreased when combined with Interferon beta-1b.
Interferon gamma-1b	The metabolism of Clonidine can be decreased when combined with Interferon gamma-1b.
Iobenguane	The therapeutic efficacy of Iobenguane can be decreased when used in combination with Clonidine.
Iofetamine I-123	Iofetamine I-123 may decrease the antihypertensive activities of Clonidine.
Ipecac	The metabolism of Clonidine can be decreased when combined with Ipecac.
Ipratropium	The risk or severity of Tachycardia can be increased when Ipratropium is combined with Clonidine.
Iptacopan	The metabolism of Clonidine can be decreased when combined with Iptacopan.
Irbesartan	The risk or severity of hypotension can be increased when Clonidine is combined with Irbesartan.
Irinotecan	The metabolism of Clonidine can be decreased when combined with Irinotecan.
Isavuconazole	The metabolism of Clonidine can be increased when combined with Isavuconazole.
Isavuconazonium	The metabolism of Clonidine can be increased when combined with Isavuconazonium.
Isocarboxazid	The risk or severity of sedation can be increased when Clonidine is combined with Isocarboxazid.
Isoetharine	Isoetharine may decrease the antihypertensive activities of Clonidine.
Isoflurane	The risk or severity of sedation can be increased when Clonidine is combined with Isoflurane.
Isometheptene	Isometheptene may decrease the antihypertensive activities of Clonidine.
Isoniazid	The metabolism of Clonidine can be decreased when combined with Isoniazid.
Isoprenaline	Isoprenaline may decrease the antihypertensive activities of Clonidine.
Isopropamide	The risk or severity of Tachycardia can be increased when Clonidine is combined with Isopropamide.
Isosorbide dinitrate	The risk or severity of adverse effects can be increased when Clonidine is combined with Isosorbide dinitrate.
Isosorbide mononitrate	The risk or severity of adverse effects can be increased when Clonidine is combined with Isosorbide mononitrate.
Isoxicam	The therapeutic efficacy of Clonidine can be decreased when used in combination with Isoxicam.
Isoxsuprine	Isoxsuprine may decrease the antihypertensive activities of Clonidine.
Isradipine	The risk or severity of hypotension can be increased when Clonidine is combined with Isradipine.
Istradefylline	The metabolism of Clonidine can be decreased when combined with Istradefylline.
Itraconazole	The metabolism of Clonidine can be decreased when combined with Itraconazole.
Ivabradine	Clonidine may increase the bradycardic activities of Ivabradine.
Ivacaftor	The serum concentration of Clonidine can be increased when it is combined with Ivacaftor.
Ivosidenib	The metabolism of Clonidine can be increased when combined with Ivosidenib.
Ketamine	The risk or severity of sedation can be increased when Clonidine is combined with Ketamine.
Ketazolam	The risk or severity of sedation can be increased when Clonidine is combined with Ketazolam.
Ketoconazole	The metabolism of Clonidine can be decreased when combined with Ketoconazole.
Ketoprofen	The therapeutic efficacy of Clonidine can be decreased when used in combination with Ketoprofen.
Ketorolac	The therapeutic efficacy of Clonidine can be decreased when used in combination with Ketorolac.
Labetalol	The risk or severity of hypotension can be increased when Clonidine is combined with Labetalol.
Lacidipine	Clonidine may increase the hypotensive activities of Lacidipine.
Lacosamide	The risk or severity of ventricular arrhythmias, bradycardia, and heart block can be increased when Clonidine is combined with Lacosamide.
Lamotrigine	The risk or severity of sedation can be increased when Clonidine is combined with Lamotrigine.
Lanreotide	The metabolism of Clonidine can be decreased when combined with Lanreotide.
Lansoprazole	The metabolism of Clonidine can be decreased when combined with Lansoprazole.
Lapatinib	The metabolism of Clonidine can be decreased when combined with Lapatinib.
Lasmiditan	The risk or severity of sedation can be increased when Clonidine is combined with Lasmiditan.
Lefamulin	The serum concentration of Clonidine can be increased when it is combined with Lefamulin.
Leflunomide	The serum concentration of Clonidine can be decreased when it is combined with Leflunomide.
Lemborexant	The risk or severity of sedation can be increased when Clonidine is combined with Lemborexant.
Lenacapavir	The metabolism of Clonidine can be decreased when combined with Lenacapavir.
Leniolisib	The metabolism of Clonidine can be decreased when combined with Leniolisib.
Lercanidipine	The risk or severity of hypotension can be increased when Clonidine is combined with Lercanidipine.
Lesinurad	The metabolism of Clonidine can be increased when combined with Lesinurad.
Letermovir	The serum concentration of Clonidine can be increased when it is combined with Letermovir.
Levacetylmethadol	The risk or severity of sedation can be increased when Clonidine is combined with Levacetylmethadol.
Levamlodipine	The risk or severity of hypotension can be increased when Clonidine is combined with Levamlodipine.
Levetiracetam	The risk or severity of sedation can be increased when Clonidine is combined with Levetiracetam.
Levobetaxolol	The metabolism of Clonidine can be decreased when combined with Levobetaxolol.
Levobupivacaine	The risk or severity of sedation can be increased when Clonidine is combined with Levobupivacaine.
Levocabastine	The risk or severity of sedation can be increased when Clonidine is combined with Levocabastine.
Levocetirizine	The risk or severity of sedation can be increased when Clonidine is combined with Levocetirizine.
Levodopa	The risk or severity of sedation can be increased when Clonidine is combined with Levodopa.
Levoketoconazole	The metabolism of Clonidine can be decreased when combined with Levoketoconazole.
Levomenthol	Clonidine may increase the bradycardic activities of Levomenthol.
Levomilnacipran	Levomilnacipran may increase the tachycardic activities of Clonidine.
Levonordefrin	Levonordefrin may decrease the antihypertensive activities of Clonidine.
Levonorgestrel	The risk or severity of sedation can be increased when Levonorgestrel is combined with Clonidine.
Levorphanol	The risk or severity of sedation can be increased when Clonidine is combined with Levorphanol.
Levosalbutamol	Levosalbutamol may decrease the antihypertensive activities of Clonidine.
Levosimendan	The risk or severity of adverse effects can be increased when Clonidine is combined with Levosimendan.
Lidocaine	The risk or severity of sedation can be increased when Clonidine is combined with Lidocaine.
Lidoflazine	Clonidine may increase the atrioventricular blocking (AV block) activities of Lidoflazine.
Linagliptin	The metabolism of Clonidine can be decreased when combined with Linagliptin.
Linezolid	Linezolid may increase the hypertensive activities of Clonidine.
Lisdexamfetamine	Lisdexamfetamine may decrease the antihypertensive activities of Clonidine.
Lisinopril	The risk or severity of hypotension can be increased when Clonidine is combined with Lisinopril.
Lisuride	The risk or severity of sedation can be increased when Clonidine is combined with Lisuride.
Lithium carbonate	The risk or severity of sedation can be increased when Clonidine is combined with Lithium carbonate.
Lofexidine	The risk or severity of sedation can be increased when Clonidine is combined with Lofexidine.
Lomefloxacin	The metabolism of Lomefloxacin can be decreased when combined with Clonidine.
Lomitapide	The metabolism of Clonidine can be decreased when combined with Lomitapide.
Lonafarnib	The metabolism of Clonidine can be decreased when combined with Lonafarnib.
Lonapegsomatropin	The metabolism of Clonidine can be increased when combined with Lonapegsomatropin.
Loperamide	Clonidine may increase the bradycardic activities of Loperamide.
Lopinavir	The metabolism of Clonidine can be decreased when combined with Lopinavir.
Lorazepam	The risk or severity of sedation can be increased when Clonidine is combined with Lorazepam.
Lorcaserin	The risk or severity of sedation can be increased when Clonidine is combined with Lorcaserin.
Lorlatinib	The metabolism of Clonidine can be increased when combined with Lorlatinib.
Lormetazepam	The risk or severity of sedation can be increased when Clonidine is combined with Lormetazepam.
Lornoxicam	The therapeutic efficacy of Clonidine can be decreased when used in combination with Lornoxicam.
Lorpiprazole	The metabolism of Clonidine can be decreased when combined with Lorpiprazole.
Losartan	The risk or severity of hypotension can be increased when Clonidine is combined with Losartan.
Lovastatin	The metabolism of Clonidine can be decreased when combined with Lovastatin.
Loxapine	The risk or severity of sedation can be increased when Clonidine is combined with Loxapine.
Loxoprofen	The therapeutic efficacy of Clonidine can be decreased when used in combination with Loxoprofen.
Lucinactant	Clonidine may increase the bradycardic activities of Lucinactant.
Lumacaftor	The serum concentration of Clonidine can be decreased when it is combined with Lumacaftor.
Lumateperone	The risk or severity of sedation can be increased when Clonidine is combined with Lumateperone.
Lumefantrine	The metabolism of Clonidine can be decreased when combined with Lumefantrine.
Lumiracoxib	The therapeutic efficacy of Clonidine can be decreased when used in combination with Lumiracoxib.
Lurasidone	The risk or severity of sedation can be increased when Clonidine is combined with Lurasidone.
Lynestrenol	The risk or severity of sedation can be increased when Lynestrenol is combined with Clonidine.
Macimorelin	The therapeutic efficacy of Macimorelin can be decreased when used in combination with Clonidine.
Macitentan	The risk or severity of hypotension can be increased when Clonidine is combined with Macitentan.
Magnesium sulfate	The risk or severity of sedation can be increased when Clonidine is combined with Magnesium sulfate.
Manidipine	The risk or severity of hypotension can be increased when Clonidine is combined with Manidipine.
Mannitol	The risk or severity of adverse effects can be increased when Clonidine is combined with Mannitol.
Maprotiline	The risk or severity of sedation can be increased when Clonidine is combined with Maprotiline.
Mavacamten	The serum concentration of Clonidine can be decreased when it is combined with Mavacamten.
Mazindol	The risk or severity of sedation can be increased when Clonidine is combined with Mazindol.
Mebeverine	The risk or severity of Tachycardia can be increased when Clonidine is combined with Mebeverine.
Mebutamate	The risk or severity of sedation can be increased when Clonidine is combined with Mebutamate.
Mecamylamine	The risk or severity of hypotension can be increased when Clonidine is combined with Mecamylamine.
Meclizine	The risk or severity of sedation can be increased when Clonidine is combined with Meclizine.
Meclofenamic acid	The therapeutic efficacy of Clonidine can be decreased when used in combination with Meclofenamic acid.
Medifoxamine	The risk or severity of sedation can be increased when Clonidine is combined with Medifoxamine.
Medroxyprogesterone acetate	The risk or severity of sedation can be increased when Medroxyprogesterone acetate is combined with Clonidine.
Mefenamic acid	The therapeutic efficacy of Clonidine can be decreased when used in combination with Mefenamic acid.
Megestrol acetate	The risk or severity of sedation can be increased when Megestrol acetate is combined with Clonidine.
Melatonin	The risk or severity of sedation can be increased when Clonidine is combined with Melatonin.
Meloxicam	The therapeutic efficacy of Clonidine can be decreased when used in combination with Meloxicam.
Menthyl salicylate	The therapeutic efficacy of Clonidine can be decreased when used in combination with Menthyl salicylate.
Mepenzolate	The risk or severity of Tachycardia can be increased when Clonidine is combined with Mepenzolate.
Meperidine	The risk or severity of sedation can be increased when Clonidine is combined with Meperidine.
Mephentermine	Mephentermine may decrease the antihypertensive activities of Clonidine.
Mephenytoin	The risk or severity of sedation can be increased when Clonidine is combined with Mephenytoin.
Mepivacaine	The risk or severity of sedation can be increased when Clonidine is combined with Mepivacaine.
Meprednisone	The metabolism of Clonidine can be increased when combined with Meprednisone.
Meprobamate	The risk or severity of sedation can be increased when Clonidine is combined with Meprobamate.
Mepyramine	The risk or severity of sedation can be increased when Clonidine is combined with Mepyramine.
Mesalazine	Mesalazine may decrease the antihypertensive activities of Clonidine.
Mesoridazine	The risk or severity of sedation can be increased when Clonidine is combined with Mesoridazine.
Mestranol	The risk or severity of sedation can be increased when Mestranol is combined with Clonidine.
Metamfetamine	The metabolism of Clonidine can be decreased when combined with Metamfetamine.
Metamizole	Metamizole may decrease the antihypertensive activities of Clonidine.
Metaraminol	Metaraminol may decrease the antihypertensive activities of Clonidine.
Metaxalone	The risk or severity of sedation can be increased when Clonidine is combined with Metaxalone.
Metergoline	The risk or severity of sedation can be increased when Clonidine is combined with Metergoline.
Methadone	The risk or severity of adverse effects can be increased when Methadone is combined with Clonidine.
Methantheline	The risk or severity of Tachycardia can be increased when Clonidine is combined with Methantheline.
Methazolamide	The risk or severity of adverse effects can be increased when Clonidine is combined with Methazolamide.
Methimazole	The metabolism of Clonidine can be decreased when combined with Methimazole.
Methocarbamol	The risk or severity of sedation can be increased when Clonidine is combined with Methocarbamol.
Methohexital	The risk or severity of sedation can be increased when Clonidine is combined with Methohexital.
Methotrimeprazine	The risk or severity of sedation can be increased when Clonidine is combined with Methotrimeprazine.
Methoxamine	Methoxamine may decrease the antihypertensive activities of Clonidine.
Methoxsalen	The metabolism of Clonidine can be decreased when combined with Methoxsalen.
Methoxyflurane	The risk or severity of sedation can be increased when Clonidine is combined with Methoxyflurane.
Methoxyphenamine	Methoxyphenamine may decrease the antihypertensive activities of Clonidine.
Methscopolamine	The risk or severity of Tachycardia can be increased when Clonidine is combined with Methscopolamine.
Methscopolamine bromide	The risk or severity of Tachycardia can be increased when Methscopolamine bromide is combined with Clonidine.
Methsuximide	The risk or severity of sedation can be increased when Clonidine is combined with Methsuximide.
Methyldopa	The risk or severity of hypotension can be increased when Clonidine is combined with Methyldopa.
Methylene blue	The risk or severity of sedation can be increased when Clonidine is combined with Methylene blue.
Methylergometrine	The serum concentration of Clonidine can be increased when it is combined with Methylergometrine.
Methylphenidate	The risk or severity of adverse effects can be increased when Methylphenidate is combined with Clonidine.
Methylphenobarbital	The risk or severity of sedation can be increased when Clonidine is combined with Methylphenobarbital.
Methylprednisolone	The metabolism of Clonidine can be increased when combined with Methylprednisolone.
Methylprednisone	The metabolism of Clonidine can be decreased when combined with Methylprednisone.
Methyprylon	The risk or severity of sedation can be increased when Clonidine is combined with Methyprylon.
Methysergide	The risk or severity of sedation can be increased when Clonidine is combined with Methysergide.
Metipranolol	Clonidine may increase the hypotensive activities of Metipranolol.
Metixene	The risk or severity of Tachycardia can be increased when Metixene is combined with Clonidine.
Metoclopramide	The risk or severity of sedation can be increased when Metoclopramide is combined with Clonidine.
Metocurine	The risk or severity of sedation can be increased when Clonidine is combined with Metocurine.
Metocurine iodide	The risk or severity of sedation can be increased when Clonidine is combined with Metocurine iodide.
Metolazone	The risk or severity of hypotension can be increased when Clonidine is combined with Metolazone.
Metoprolol	The risk or severity of hypotension can be increased when Clonidine is combined with Metoprolol.
Metreleptin	The metabolism of Clonidine can be increased when combined with Metreleptin.
Metronidazole	The serum concentration of Clonidine can be increased when it is combined with Metronidazole.
Metyrapone	The metabolism of Clonidine can be increased when combined with Metyrapone.
Metyrosine	The risk or severity of hypotension can be increased when Clonidine is combined with Metyrosine.
Mexiletine	The metabolism of Clonidine can be decreased when combined with Mexiletine.
Mianserin	The risk or severity of sedation can be increased when Clonidine is combined with Mianserin.
Miconazole	The metabolism of Clonidine can be decreased when combined with Miconazole.
Midazolam	The risk or severity of sedation can be increased when Clonidine is combined with Midazolam.
Midodrine	Midodrine may decrease the antihypertensive activities of Clonidine.
Midostaurin	The metabolism of Clonidine can be decreased when combined with Midostaurin.
Mifepristone	The risk or severity of sedation can be increased when Mifepristone is combined with Clonidine.
Milnacipran	The risk or severity of sedation can be increased when Clonidine is combined with Milnacipran.
Minaprine	The risk or severity of sedation can be increased when Clonidine is combined with Minaprine.
Minocycline	Minocycline may increase the central nervous system depressant (CNS depressant) activities of Clonidine.
Minoxidil	The risk or severity of hypotension can be increased when Clonidine is combined with Minoxidil.
Miocamycin	The serum concentration of Clonidine can be increased when it is combined with Miocamycin.
Mirabegron	The serum concentration of Clonidine can be increased when it is combined with Mirabegron.
Mirtazapine	The risk or severity of sedation can be increased when Clonidine is combined with Mirtazapine.
Mitapivat	The metabolism of Clonidine can be increased when combined with Mitapivat.
Mitotane	The metabolism of Clonidine can be increased when combined with Mitotane.
Mivacurium	The risk or severity of sedation can be increased when Clonidine is combined with Mivacurium.
Mobocertinib	The serum concentration of Clonidine can be decreased when it is combined with Mobocertinib.
Moclobemide	The risk or severity of sedation can be increased when Clonidine is combined with Moclobemide.
Modafinil	The metabolism of Clonidine can be increased when combined with Modafinil.
Moexipril	The risk or severity of hypotension can be increased when Clonidine is combined with Moexipril.
Molindone	The risk or severity of sedation can be increased when Clonidine is combined with Molindone.
Molsidomine	Molsidomine may increase the hypotensive activities of Clonidine.
Mometasone furoate	The metabolism of Clonidine can be increased when combined with Mometasone furoate.
Moricizine	The risk or severity of sedation can be increased when Clonidine is combined with Moricizine.
Morphine	The risk or severity of sedation can be increased when Clonidine is combined with Morphine.
Mosunetuzumab	The metabolism of Clonidine can be decreased when combined with Mosunetuzumab.
Moxifloxacin	The metabolism of Clonidine can be decreased when combined with Moxifloxacin.
Moxisylyte	Moxisylyte may decrease the antihypertensive activities of Clonidine.
Moxonidine	The risk or severity of hypotension can be increased when Clonidine is combined with Moxonidine.
Muzolimine	The risk or severity of hypotension can be increased when Clonidine is combined with Muzolimine.
Mycophenolate mofetil	The metabolism of Clonidine can be decreased when combined with Mycophenolate mofetil.
Nabilone	The risk or severity of sedation can be increased when Clonidine is combined with Nabilone.
Nabumetone	The therapeutic efficacy of Clonidine can be decreased when used in combination with Nabumetone.
Nadolol	The risk or severity of hypotension can be increased when Clonidine is combined with Nadolol.
Nafcillin	The metabolism of Clonidine can be increased when combined with Nafcillin.
Nalbuphine	The risk or severity of sedation can be increased when Clonidine is combined with Nalbuphine.
Nalidixic acid	The metabolism of Clonidine can be decreased when combined with Nalidixic acid.
Naloxegol	The risk or severity of hypotension can be increased when Naloxegol is combined with Clonidine.
Naltrexone	The risk or severity of hypotension can be increased when Naltrexone is combined with Clonidine.
Naphazoline	Naphazoline may decrease the antihypertensive activities of Clonidine.
Naproxen	The therapeutic efficacy of Clonidine can be decreased when used in combination with Naproxen.
Naratriptan	The risk or severity of sedation can be increased when Clonidine is combined with Naratriptan.
Nateglinide	The metabolism of Clonidine can be decreased when combined with Nateglinide.
Naxitamab	Naxitamab may decrease the antihypertensive activities of Clonidine.
Nebivolol	The risk or severity of hypotension can be increased when Clonidine is combined with Nebivolol.
Nefazodone	The risk or severity of sedation can be increased when Clonidine is combined with Nefazodone.
Nelfinavir	The metabolism of Clonidine can be decreased when combined with Nelfinavir.
Nesiritide	The risk or severity of adverse effects can be increased when Clonidine is combined with Nesiritide.
Netupitant	The metabolism of Clonidine can be decreased when combined with Netupitant.
Nevirapine	The metabolism of Clonidine can be decreased when combined with Nevirapine.
Niacin	The serum concentration of Clonidine can be increased when it is combined with Niacin.
Nialamide	The risk or severity of sedation can be increased when Clonidine is combined with Nialamide.
Nicardipine	The risk or severity of hypotension can be increased when Clonidine is combined with Nicardipine.
Nicergoline	The metabolism of Clonidine can be decreased when combined with Nicergoline.
Niclosamide	The metabolism of Clonidine can be decreased when combined with Niclosamide.
Nicorandil	The risk or severity of hypotension can be increased when Clonidine is combined with Nicorandil.
Nicotine	The risk or severity of Tachycardia can be increased when Nicotine is combined with Clonidine.
Nifedipine	Clonidine may increase the atrioventricular blocking (AV block) activities of Nifedipine.
Nilotinib	The metabolism of Clonidine can be decreased when combined with Nilotinib.
Nilvadipine	The risk or severity of hypotension can be increased when Clonidine is combined with Nilvadipine.
Nimesulide	Clonidine may increase the atrioventricular blocking (AV block) activities of Nimesulide.
Nimodipine	The risk or severity of hypotension can be increased when Clonidine is combined with Nimodipine.
Nintedanib	The metabolism of Clonidine can be decreased when combined with Nintedanib.
Nirogacestat	The metabolism of Clonidine can be decreased when combined with Nirogacestat.
Nisoldipine	The risk or severity of hypotension can be increased when Clonidine is combined with Nisoldipine.
Nitrazepam	The risk or severity of sedation can be increased when Clonidine is combined with Nitrazepam.
Nitrendipine	The risk or severity of hypotension can be increased when Clonidine is combined with Nitrendipine.
Nitric Oxide	The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Clonidine.
Nitroglycerin	The risk or severity of hypotension can be increased when Clonidine is combined with Nitroglycerin.
Nitroprusside	The risk or severity of hypotension can be increased when Clonidine is combined with Nitroprusside.
Nitrous acid	The risk or severity of adverse effects can be increased when Clonidine is combined with Nitrous acid.
Nitrous oxide	The risk or severity of sedation can be increased when Clonidine is combined with Nitrous oxide.
Nomegestrol acetate	The risk or severity of sedation can be increased when Nomegestrol acetate is combined with Clonidine.
Nomifensine	The risk or severity of sedation can be increased when Clonidine is combined with Nomifensine.
Norepinephrine	Norepinephrine may decrease the antihypertensive activities of Clonidine.
Norethisterone	The risk or severity of sedation can be increased when Norethisterone is combined with Clonidine.
Norethynodrel	The risk or severity of sedation can be increased when Norethynodrel is combined with Clonidine.
Norfloxacin	The metabolism of Clonidine can be decreased when combined with Norfloxacin.
Norgestimate	The risk or severity of sedation can be increased when Norgestimate is combined with Clonidine.
Norgestrel	The risk or severity of sedation can be increased when Norgestrel is combined with Clonidine.
Normethadone	The risk or severity of sedation can be increased when Clonidine is combined with Normethadone.
Nortriptyline	The risk or severity of sedation can be increased when Clonidine is combined with Nortriptyline.
Noscapine	The serum concentration of Clonidine can be increased when it is combined with Noscapine.
Nylidrin	Clonidine may increase the atrioventricular blocking (AV block) activities of Nylidrin.
Obeticholic acid	The risk or severity of adverse effects can be increased when Obeticholic acid is combined with Clonidine.
Obinutuzumab	Clonidine may increase the hypotensive activities of Obinutuzumab.
Octreotide	The serum concentration of the active metabolites of Octreotide can be increased when Octreotide is used in combination with Clonidine.
Olanzapine	The risk or severity of sedation can be increased when Clonidine is combined with Olanzapine.
Olaparib	The metabolism of Clonidine can be decreased when combined with Olaparib.
Oliceridine	The risk or severity of sedation can be increased when Clonidine is combined with Oliceridine.
Olmesartan	The risk or severity of hypotension can be increased when Clonidine is combined with Olmesartan.
Olodaterol	Olodaterol may decrease the antihypertensive activities of Clonidine.
Olutasidenib	The metabolism of Clonidine can be increased when combined with Olutasidenib.
Omaveloxolone	The serum concentration of Clonidine can be decreased when it is combined with Omaveloxolone.
Ondansetron	The risk or severity of sedation can be increased when Clonidine is combined with Ondansetron.
Opicapone	The risk or severity of adverse effects can be increased when Clonidine is combined with Opicapone.
Opium	The risk or severity of sedation can be increased when Clonidine is combined with Opium.
Orciprenaline	Orciprenaline may decrease the antihypertensive activities of Clonidine.
Oritavancin	The metabolism of Clonidine can be increased when combined with Oritavancin.
Orphenadrine	The risk or severity of sedation can be increased when Clonidine is combined with Orphenadrine.
Osilodrostat	The serum concentration of Clonidine can be increased when it is combined with Osilodrostat.
Osimertinib	The serum concentration of Clonidine can be decreased when it is combined with Osimertinib.
Ospemifene	The metabolism of Clonidine can be decreased when combined with Ospemifene.
Ouabain	Clonidine may increase the atrioventricular blocking (AV block) activities of Ouabain.
Oxamniquine	The metabolism of Clonidine can be decreased when combined with Oxamniquine.
Oxaprozin	The therapeutic efficacy of Clonidine can be decreased when used in combination with Oxaprozin.
Oxazepam	The risk or severity of sedation can be increased when Clonidine is combined with Oxazepam.
Oxcarbazepine	The risk or severity of sedation can be increased when Clonidine is combined with Oxcarbazepine.
Oxitriptan	The risk or severity of sedation can be increased when Clonidine is combined with Oxitriptan.
Oxprenolol	The risk or severity of sedation can be increased when Clonidine is combined with Oxprenolol.
Oxtriphylline	The metabolism of Oxtriphylline can be decreased when combined with Clonidine.
Oxybuprocaine	The risk or severity of sedation can be increased when Clonidine is combined with Oxybuprocaine.
Oxybutynin	The serum concentration of Clonidine can be increased when it is combined with Oxybutynin.
Oxycodone	The risk or severity of sedation can be increased when Clonidine is combined with Oxycodone.
Oxymetazoline	The therapeutic efficacy of Clonidine can be decreased when used in combination with Oxymetazoline.
Oxymorphone	The risk or severity of sedation can be increased when Clonidine is combined with Oxymorphone.
Oxyphenbutazone	The therapeutic efficacy of Clonidine can be decreased when used in combination with Oxyphenbutazone.
Oxyphencyclimine	The risk or severity of Tachycardia can be increased when Oxyphencyclimine is combined with Clonidine.
Oxyphenonium	The risk or severity of Tachycardia can be increased when Oxyphenonium is combined with Clonidine.
Paclitaxel	The metabolism of Clonidine can be increased when combined with Paclitaxel.
Pacritinib	The serum concentration of Clonidine can be increased when it is combined with Pacritinib.
Palbociclib	The metabolism of Clonidine can be decreased when combined with Palbociclib.
Paliperidone	The risk or severity of sedation can be increased when Clonidine is combined with Paliperidone.
Palonosetron	The risk or severity of sedation can be increased when Clonidine is combined with Palonosetron.
Palovarotene	The metabolism of Clonidine can be increased when combined with Palovarotene.
Pancuronium	The risk or severity of sedation can be increased when Clonidine is combined with Pancuronium.
Panobinostat	The metabolism of Clonidine can be decreased when combined with Panobinostat.
Papaverine	The risk or severity of adverse effects can be increased when Clonidine is combined with Papaverine.
Paraldehyde	The risk or severity of sedation can be increased when Clonidine is combined with Paraldehyde.
Paramethadione	The risk or severity of sedation can be increased when Clonidine is combined with Paramethadione.
Parecoxib	The therapeutic efficacy of Clonidine can be decreased when used in combination with Parecoxib.
Pargyline	The risk or severity of sedation can be increased when Clonidine is combined with Pargyline.
Paritaprevir	The metabolism of Clonidine can be decreased when combined with Paritaprevir.
Paroxetine	The risk or severity of sedation can be increased when Clonidine is combined with Paroxetine.
Pasireotide	The metabolism of Clonidine can be decreased when combined with Pasireotide.
Pazopanib	The metabolism of Clonidine can be decreased when combined with Pazopanib.
Pefloxacin	The metabolism of Clonidine can be decreased when combined with Pefloxacin.
Peginterferon alfa-2a	The metabolism of Clonidine can be decreased when combined with Peginterferon alfa-2a.
Peginterferon alfa-2b	The serum concentration of Clonidine can be increased when it is combined with Peginterferon alfa-2b.
Pemetrexed	The metabolism of Pemetrexed can be decreased when combined with Clonidine.
Penbutolol	The risk or severity of sedation can be increased when Clonidine is combined with Penbutolol.
Penciclovir	The metabolism of Clonidine can be decreased when combined with Penciclovir.
Pentamidine	The metabolism of Clonidine can be decreased when combined with Pentamidine.
Pentazocine	The risk or severity of sedation can be increased when Clonidine is combined with Pentazocine.
Pentobarbital	The risk or severity of sedation can be increased when Clonidine is combined with Pentobarbital.
Pentolinium	The risk or severity of hypotension can be increased when Clonidine is combined with Pentolinium.
Pentoxifylline	Pentoxifylline may increase the hypotensive activities of Clonidine.
Perampanel	The risk or severity of sedation can be increased when Clonidine is combined with Perampanel.
Perazine	The risk or severity of sedation can be increased when Clonidine is combined with Perazine.
Pergolide	The risk or severity of sedation can be increased when Clonidine is combined with Pergolide.
Perhexiline	Clonidine may increase the atrioventricular blocking (AV block) activities of Perhexiline.
Periciazine	The risk or severity of sedation can be increased when Clonidine is combined with Periciazine.
Perindopril	The risk or severity of hypotension can be increased when Clonidine is combined with Perindopril.
Perphenazine	The risk or severity of sedation can be increased when Clonidine is combined with Perphenazine.
Phenacemide	The risk or severity of sedation can be increased when Clonidine is combined with Phenacemide.
Phendimetrazine	Phendimetrazine may decrease the antihypertensive activities of Clonidine.
Phenelzine	The risk or severity of sedation can be increased when Clonidine is combined with Phenelzine.
Phenformin	The metabolism of Clonidine can be decreased when combined with Phenformin.
Phenmetrazine	Phenmetrazine may decrease the antihypertensive activities of Clonidine.
Phenobarbital	The risk or severity of sedation can be increased when Clonidine is combined with Phenobarbital.
Phenoxybenzamine	The risk or severity of hypotension can be increased when Clonidine is combined with Phenoxybenzamine.
Phensuximide	The risk or severity of sedation can be increased when Clonidine is combined with Phensuximide.
Phentermine	Phentermine may decrease the antihypertensive activities of Clonidine.
Phentolamine	The risk or severity of hypotension can be increased when Clonidine is combined with Phentolamine.
Phenylbutazone	The metabolism of Clonidine can be increased when combined with Phenylbutazone.
Phenylbutyric acid	The metabolism of Clonidine can be decreased when combined with Phenylbutyric acid.
Phenylephrine	The metabolism of Clonidine can be increased when combined with Phenylephrine.
Phenylpropanolamine	Phenylpropanolamine may decrease the antihypertensive activities of Clonidine.
Phenytoin	The risk or severity of sedation can be increased when Clonidine is combined with Phenytoin.
Pimavanserin	The metabolism of Clonidine can be decreased when combined with Pimavanserin.
Pimozide	The risk or severity of sedation can be increased when Clonidine is combined with Pimozide.
Pinacidil	The risk or severity of hypotension can be increased when Clonidine is combined with Pinacidil.
Pinaverium	Clonidine may increase the atrioventricular blocking (AV block) activities of Pinaverium.
Pindolol	The risk or severity of sedation can be increased when Clonidine is combined with Pindolol.
Pipecuronium	The risk or severity of sedation can be increased when Clonidine is combined with Pipecuronium.
Piperaquine	The metabolism of Clonidine can be decreased when combined with Piperaquine.
Piperazine	The metabolism of Clonidine can be decreased when combined with Piperazine.
Pipotiazine	The risk or severity of sedation can be increased when Clonidine is combined with Pipotiazine.
Pirbuterol	Pirbuterol may decrease the antihypertensive activities of Clonidine.
Pirenzepine	The risk or severity of Tachycardia can be increased when Clonidine is combined with Pirenzepine.
Pirfenidone	The metabolism of Clonidine can be decreased when combined with Pirfenidone.
Piritramide	The risk or severity of sedation can be increased when Clonidine is combined with Piritramide.
Piroxicam	The therapeutic efficacy of Clonidine can be decreased when used in combination with Piroxicam.
Pirtobrutinib	The metabolism of Clonidine can be decreased when combined with Pirtobrutinib.
Pitolisant	The serum concentration of Clonidine can be decreased when it is combined with Pitolisant.
Pizotifen	The risk or severity of sedation can be increased when Clonidine is combined with Pizotifen.
Polythiazide	The risk or severity of hypotension can be increased when Clonidine is combined with Polythiazide.
Pomalidomide	The risk or severity of sedation can be increased when Clonidine is combined with Pomalidomide.
Ponatinib	The metabolism of Ponatinib can be decreased when combined with Clonidine.
Ponesimod	The risk or severity of bradycardia can be increased when Ponesimod is combined with Clonidine.
Poractant alfa	Clonidine may increase the bradycardic activities of Poractant alfa.
Posaconazole	The metabolism of Clonidine can be decreased when combined with Posaconazole.
Practolol	The risk or severity of hypotension can be increased when Clonidine is combined with Practolol.
Pralsetinib	The metabolism of Clonidine can be increased when combined with Pralsetinib.
Pramipexole	Clonidine may increase the sedative activities of Pramipexole.
Pramocaine	The risk or severity of sedation can be increased when Clonidine is combined with Pramocaine.
Prazepam	The risk or severity of sedation can be increased when Clonidine is combined with Prazepam.
Praziquantel	The metabolism of Clonidine can be decreased when combined with Praziquantel.
Prazosin	The risk or severity of hypotension can be increased when Prazosin is combined with Clonidine.
Prednisolone	The metabolism of Clonidine can be increased when combined with Prednisolone.
Prednisolone acetate	The metabolism of Clonidine can be increased when combined with Prednisolone acetate.
Prednisolone phosphate	The metabolism of Clonidine can be increased when combined with Prednisolone phosphate.
Prednisone acetate	The metabolism of Clonidine can be increased when combined with Prednisone acetate.
Pregabalin	The risk or severity of sedation can be increased when Clonidine is combined with Pregabalin.
Prenylamine	Clonidine may increase the atrioventricular blocking (AV block) activities of Prenylamine.
Pretomanid	The metabolism of Clonidine can be decreased when combined with Pretomanid.
Prilocaine	The risk or severity of sedation can be increased when Clonidine is combined with Prilocaine.
Primaquine	The metabolism of Clonidine can be decreased when combined with Primaquine.
Primidone	The risk or severity of sedation can be increased when Clonidine is combined with Primidone.
Probenecid	The metabolism of Clonidine can be increased when combined with Probenecid.
Procainamide	The metabolism of Procainamide can be decreased when combined with Clonidine.
Procaine	The risk or severity of sedation can be increased when Clonidine is combined with Procaine.
Procarbazine	The risk or severity of sedation can be increased when Clonidine is combined with Procarbazine.
Procaterol	Procaterol may decrease the antihypertensive activities of Clonidine.
Prochlorperazine	The risk or severity of sedation can be increased when Clonidine is combined with Prochlorperazine.
Procyclidine	The risk or severity of Tachycardia can be increased when Procyclidine is combined with Clonidine.
Profenamine	The therapeutic efficacy of Clonidine can be decreased when used in combination with Profenamine.
Progesterone	The metabolism of Clonidine can be decreased when combined with Progesterone.
Proguanil	The metabolism of Clonidine can be decreased when combined with Proguanil.
Promazine	The risk or severity of sedation can be increased when Clonidine is combined with Promazine.
Promethazine	The risk or severity of sedation can be increased when Clonidine is combined with Promethazine.
Propafenone	The metabolism of Clonidine can be decreased when combined with Propafenone.
Propantheline	The risk or severity of Tachycardia can be increased when Clonidine is combined with Propantheline.
Propiomazine	The risk or severity of sedation can be increased when Clonidine is combined with Propiomazine.
Propiverine	The therapeutic efficacy of Clonidine can be decreased when used in combination with Propiverine.
Propofol	The risk or severity of sedation can be increased when Clonidine is combined with Propofol.
Propranolol	The risk or severity of hypotension can be increased when Clonidine is combined with Propranolol.
Protokylol	The risk or severity of Tachycardia can be increased when Clonidine is combined with Protokylol.
Protriptyline	The risk or severity of sedation can be increased when Clonidine is combined with Protriptyline.
Proxibarbal	The risk or severity of sedation can be increased when Clonidine is combined with Proxibarbal.
Pseudoephedrine	Pseudoephedrine may decrease the antihypertensive activities of Clonidine.
Pyrantel	The risk or severity of sedation can be increased when Clonidine is combined with Pyrantel.
Quazepam	The risk or severity of sedation can be increased when Clonidine is combined with Quazepam.
Quetiapine	The risk or severity of sedation can be increased when Clonidine is combined with Quetiapine.
Quinapril	The risk or severity of hypotension can be increased when Clonidine is combined with Quinapril.
Quinidine	The metabolism of Clonidine can be decreased when combined with Quinidine.
Quinine	The risk or severity of sedation can be increased when Clonidine is combined with Quinine.
Quinupramine	The risk or severity of sedation can be increased when Clonidine is combined with Quinupramine.
Quinupristin	The metabolism of Clonidine can be decreased when combined with Quinupristin.
Quizartinib	The metabolism of Clonidine can be decreased when combined with Quizartinib.
Racepinephrine	Racepinephrine may decrease the antihypertensive activities of Clonidine.
Raloxifene	The serum concentration of Clonidine can be increased when it is combined with Raloxifene.
Ramelteon	The risk or severity of sedation can be increased when Clonidine is combined with Ramelteon.
Ramipril	The risk or severity of hypotension can be increased when Clonidine is combined with Ramipril.
Ranitidine	The metabolism of Clonidine can be decreased when combined with Ranitidine.
Ranolazine	The serum concentration of Clonidine can be increased when it is combined with Ranolazine.
Rapacuronium	The risk or severity of sedation can be increased when Clonidine is combined with Rapacuronium.
Rasagiline	The risk or severity of sedation can be increased when Clonidine is combined with Rasagiline.
Reboxetine	The risk or severity of sedation can be increased when Clonidine is combined with Reboxetine.
Regorafenib	Clonidine may increase the bradycardic activities of Regorafenib.
Relugolix	The metabolism of Clonidine can be decreased when combined with Relugolix.
Remdesivir	The metabolism of Clonidine can be decreased when combined with Remdesivir.
Remifentanil	The risk or severity of sedation can be increased when Clonidine is combined with Remifentanil.
Remimazolam	The risk or severity of sedation can be increased when Clonidine is combined with Remimazolam.
Remoxipride	The risk or severity of sedation can be increased when Clonidine is combined with Remoxipride.
Repotrectinib	The serum concentration of Clonidine can be decreased when it is combined with Repotrectinib.
Rescinnamine	The risk or severity of hypotension can be increased when Clonidine is combined with Rescinnamine.
Reserpine	The risk or severity of sedation can be increased when Clonidine is combined with Reserpine.
Revefenacin	The metabolism of Clonidine can be decreased when combined with Revefenacin.
Ribociclib	The metabolism of Clonidine can be decreased when combined with Ribociclib.
Rifabutin	The metabolism of Clonidine can be increased when combined with Rifabutin.
Rifampicin	The metabolism of Clonidine can be increased when combined with Rifampicin.
Rifamycin	The metabolism of Clonidine can be increased when combined with Rifamycin.
Rifapentine	The metabolism of Clonidine can be increased when combined with Rifapentine.
Rilmenidine	The risk or severity of hypotension can be increased when Clonidine is combined with Rilmenidine.
Rilonacept	The metabolism of Clonidine can be increased when combined with Rilonacept.
Rilpivirine	The metabolism of Clonidine can be decreased when combined with Rilpivirine.
Riluzole	The risk or severity of sedation can be increased when Clonidine is combined with Riluzole.
Rimonabant	The risk or severity of adverse effects can be increased when Rimonabant is combined with Clonidine.
Riociguat	The risk or severity of hypotension can be increased when Clonidine is combined with Riociguat.
Risperidone	The risk or severity of sedation can be increased when Clonidine is combined with Risperidone.
Ritlecitinib	The serum concentration of Clonidine can be increased when it is combined with Ritlecitinib.
Ritodrine	Ritodrine may decrease the antihypertensive activities of Clonidine.
Ritonavir	The serum concentration of Clonidine can be increased when it is combined with Ritonavir.
Rituximab	Clonidine may increase the hypotensive activities of Rituximab.
Rivaroxaban	The metabolism of Clonidine can be decreased when combined with Rivaroxaban.
Rivastigmine	Clonidine may increase the bradycardic activities of Rivastigmine.
Rizatriptan	Rizatriptan may decrease the antihypertensive activities of Clonidine.
Rocuronium	The risk or severity of sedation can be increased when Clonidine is combined with Rocuronium.
Rofecoxib	The metabolism of Clonidine can be increased when combined with Rofecoxib.
Roflumilast	The metabolism of Clonidine can be decreased when combined with Roflumilast.
Rolapitant	The metabolism of Clonidine can be decreased when combined with Rolapitant.
Romidepsin	The metabolism of Clonidine can be decreased when combined with Romidepsin.
Ropeginterferon alfa-2b	The risk or severity of neuropsychiatric effects can be increased when Ropeginterferon alfa-2b is combined with Clonidine.
Ropinirole	Clonidine may increase the sedative activities of Ropinirole.
Ropivacaine	The risk or severity of sedation can be increased when Clonidine is combined with Ropivacaine.
Rosoxacin	The metabolism of Clonidine can be decreased when combined with Rosoxacin.
Rosuvastatin	The metabolism of Clonidine can be decreased when combined with Rosuvastatin.
Rotigotine	The risk or severity of sedation can be increased when Clonidine is combined with Rotigotine.
Roxithromycin	The metabolism of Clonidine can be decreased when combined with Roxithromycin.
Rucaparib	The metabolism of Clonidine can be decreased when combined with Rucaparib.
Rufinamide	The risk or severity of sedation can be increased when Clonidine is combined with Rufinamide.
Rupatadine	The metabolism of Clonidine can be decreased when combined with Rupatadine.
Ruxolitinib	Ruxolitinib may increase the bradycardic activities of Clonidine.
Sacubitril	The risk or severity of adverse effects can be increased when Clonidine is combined with Sacubitril.
Safinamide	The risk or severity of sedation can be increased when Clonidine is combined with Safinamide.
Salicylamide	The therapeutic efficacy of Clonidine can be decreased when used in combination with Salicylamide.
Salicylic acid	The therapeutic efficacy of Clonidine can be decreased when used in combination with Salicylic acid.
Salmeterol	The metabolism of Clonidine can be decreased when combined with Salmeterol.
Salsalate	The therapeutic efficacy of Clonidine can be decreased when used in combination with Salsalate.
Samidorphan	The risk or severity of sedation can be increased when Clonidine is combined with Samidorphan.
Saquinavir	The metabolism of Clonidine can be decreased when combined with Saquinavir.
Sarilumab	The metabolism of Clonidine can be increased when combined with Sarilumab.
Satralizumab	The serum concentration of Clonidine can be decreased when it is combined with Satralizumab.
Saxagliptin	The metabolism of Clonidine can be decreased when combined with Saxagliptin.
Scopolamine	The risk or severity of sedation can be increased when Clonidine is combined with Scopolamine.
Secobarbital	The risk or severity of sedation can be increased when Clonidine is combined with Secobarbital.
Secukinumab	The metabolism of Clonidine can be increased when combined with Secukinumab.
Selegiline	The risk or severity of sedation can be increased when Clonidine is combined with Selegiline.
Selexipag	The risk or severity of hypotension can be increased when Clonidine is combined with Selexipag.
Selpercatinib	Selpercatinib may decrease the antihypertensive activities of Clonidine.
Selumetinib	The metabolism of Clonidine can be decreased when combined with Selumetinib.
Serdexmethylphenidate	The therapeutic efficacy of Clonidine can be decreased when used in combination with Serdexmethylphenidate.
Sertindole	The risk or severity of sedation can be increased when Clonidine is combined with Sertindole.
Sertraline	The risk or severity of sedation can be increased when Clonidine is combined with Sertraline.
Sevoflurane	The risk or severity of sedation can be increased when Clonidine is combined with Sevoflurane.
Sibutramine	The risk or severity of sedation can be increased when Clonidine is combined with Sibutramine.
Sildenafil	The metabolism of Clonidine can be decreased when combined with Sildenafil.
Silodosin	The risk or severity of orthostatic hypotension and dizziness can be increased when Clonidine is combined with Silodosin.
Siltuximab	The metabolism of Clonidine can be increased when combined with Siltuximab.
Simeprevir	The metabolism of Clonidine can be decreased when combined with Simeprevir.
Simvastatin	The metabolism of Clonidine can be decreased when combined with Simvastatin.
Siponimod	The metabolism of Clonidine can be decreased when combined with Siponimod.
Sirolimus	The metabolism of Sirolimus can be decreased when combined with Clonidine.
Sitaxentan	The risk or severity of hypotension can be increased when Clonidine is combined with Sitaxentan.
Sodium ferric gluconate complex	The risk or severity of hypotension can be increased when Sodium ferric gluconate complex is combined with Clonidine.
Sodium oxybate	Clonidine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Solifenacin	The metabolism of Clonidine can be decreased when combined with Solifenacin.
Solriamfetol	The risk or severity of sedation can be increased when Clonidine is combined with Solriamfetol.
Somapacitan	The metabolism of Clonidine can be increased when combined with Somapacitan.
Somatostatin	The metabolism of Clonidine can be decreased when combined with Somatostatin.
Somatotropin	The metabolism of Clonidine can be increased when combined with Somatotropin.
Somatrem	The metabolism of Clonidine can be increased when combined with Somatrem.
Somatrogon	The metabolism of Clonidine can be increased when combined with Somatrogon.
Sorafenib	The metabolism of Clonidine can be decreased when combined with Sorafenib.
Sotalol	The risk or severity of bradycardia can be increased when Clonidine is combined with Sotalol.
Sotorasib	The serum concentration of Clonidine can be decreased when it is combined with Sotorasib.
Spirapril	The risk or severity of hypotension can be increased when Clonidine is combined with Spirapril.
Spironolactone	The risk or severity of hypotension can be increased when Clonidine is combined with Spironolactone.
St. John's Wort	The risk or severity of sedation can be increased when Clonidine is combined with St. John's Wort.
Stiripentol	The risk or severity of sedation can be increased when Clonidine is combined with Stiripentol.
Streptokinase	The risk or severity of adverse effects can be increased when Streptokinase is combined with Clonidine.
Succinylcholine	The risk or severity of sedation can be increased when Clonidine is combined with Succinylcholine.
Sufentanil	The risk or severity of sedation can be increased when Clonidine is combined with Sufentanil.
Sulfamethoxazole	The serum concentration of Clonidine can be increased when it is combined with Sulfamethoxazole.
Sulfaphenazole	The metabolism of Clonidine can be decreased when combined with Sulfaphenazole.
Sulfasalazine	The therapeutic efficacy of Clonidine can be decreased when used in combination with Sulfasalazine.
Sulfinpyrazone	The metabolism of Clonidine can be increased when combined with Sulfinpyrazone.
Sulindac	The therapeutic efficacy of Clonidine can be decreased when used in combination with Sulindac.
Sulpiride	The risk or severity of sedation can be increased when Clonidine is combined with Sulpiride.
Sulthiame	The risk or severity of sedation can be increased when Clonidine is combined with Sulthiame.
Sultopride	The risk or severity of sedation can be increased when Clonidine is combined with Sultopride.
Sumatriptan	The risk or severity of sedation can be increased when Clonidine is combined with Sumatriptan.
Sunitinib	The metabolism of Sunitinib can be decreased when combined with Clonidine.
Suvorexant	The risk or severity of sedation can be increased when Clonidine is combined with Suvorexant.
Tacrine	The metabolism of Clonidine can be decreased when combined with Tacrine.
Tacrolimus	The metabolism of Clonidine can be decreased when combined with Tacrolimus.
Tadalafil	The risk or severity of hypotension can be increased when Clonidine is combined with Tadalafil.
Tafenoquine	The metabolism of Clonidine can be decreased when combined with Tafenoquine.
Talbutal	The risk or severity of sedation can be increased when Clonidine is combined with Talbutal.
Tamoxifen	The metabolism of Clonidine can be increased when combined with Tamoxifen.
Tamsulosin	The metabolism of Clonidine can be decreased when combined with Tamsulosin.
Tapentadol	The risk or severity of sedation can be increased when Clonidine is combined with Tapentadol.
Tasimelteon	The risk or severity of sedation can be increased when Clonidine is combined with Tasimelteon.
Tazemetostat	The metabolism of Clonidine can be decreased when combined with Tazemetostat.
Tecovirimat	The metabolism of Clonidine can be increased when combined with Tecovirimat.
Tegafur	The metabolism of Tegafur can be decreased when combined with Clonidine.
Tegaserod	The metabolism of Clonidine can be decreased when combined with Tegaserod.
Telaprevir	The metabolism of Clonidine can be decreased when combined with Telaprevir.
Telithromycin	The metabolism of Clonidine can be decreased when combined with Telithromycin.
Telmisartan	The risk or severity of hypotension can be increased when Clonidine is combined with Telmisartan.
Telotristat ethyl	The serum concentration of Clonidine can be decreased when it is combined with Telotristat ethyl.
Temazepam	The risk or severity of sedation can be increased when Clonidine is combined with Temazepam.
Temsirolimus	The metabolism of Clonidine can be decreased when combined with Temsirolimus.
Teniposide	The serum concentration of Clonidine can be increased when it is combined with Teniposide.
Tenofovir alafenamide	The metabolism of Clonidine can be decreased when combined with Tenofovir alafenamide.
Tenoxicam	The therapeutic efficacy of Clonidine can be decreased when used in combination with Tenoxicam.
Terazosin	The risk or severity of hypotension can be increased when Clonidine is combined with Terazosin.
Terbinafine	The metabolism of Clonidine can be decreased when combined with Terbinafine.
Terbutaline	Terbutaline may decrease the antihypertensive activities of Clonidine.
Terfenadine	The metabolism of Clonidine can be decreased when combined with Terfenadine.
Teriflunomide	The serum concentration of Clonidine can be decreased when it is combined with Teriflunomide.
Testosterone	The metabolism of Clonidine can be increased when combined with Testosterone.
Testosterone cypionate	The metabolism of Clonidine can be decreased when combined with Testosterone cypionate.
Testosterone enanthate	The metabolism of Clonidine can be decreased when combined with Testosterone enanthate.
Testosterone undecanoate	Testosterone undecanoate may increase the hypertensive activities of Clonidine.
Tetrabenazine	The metabolism of Clonidine can be decreased when combined with Tetrabenazine.
Tetracaine	The risk or severity of sedation can be increased when Clonidine is combined with Tetracaine.
Tetracycline	The serum concentration of Clonidine can be increased when it is combined with Tetracycline.
Tetryzoline	Tetryzoline may decrease the antihypertensive activities of Clonidine.
Tezacaftor	The metabolism of Clonidine can be decreased when combined with Tezacaftor.
Thalidomide	Clonidine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Theophylline	The metabolism of Clonidine can be decreased when combined with Theophylline.
Thiabendazole	The metabolism of Clonidine can be decreased when combined with Thiabendazole.
Thiamylal	The risk or severity of sedation can be increased when Clonidine is combined with Thiamylal.
Thiethylperazine	The risk or severity of sedation can be increased when Clonidine is combined with Thiethylperazine.
Thiopental	The risk or severity of sedation can be increased when Clonidine is combined with Thiopental.
Thioridazine	The risk or severity of sedation can be increased when Clonidine is combined with Thioridazine.
Thiothixene	The risk or severity of sedation can be increased when Clonidine is combined with Thiothixene.
Thonzylamine	The risk or severity of Tachycardia can be increased when Clonidine is combined with Thonzylamine.
Tiagabine	The risk or severity of sedation can be increased when Clonidine is combined with Tiagabine.
Tiaprofenic acid	The therapeutic efficacy of Clonidine can be decreased when used in combination with Tiaprofenic acid.
Ticagrelor	The metabolism of Clonidine can be decreased when combined with Ticagrelor.
Ticlopidine	The metabolism of Clonidine can be decreased when combined with Ticlopidine.
Timolol	Timolol may increase the hypertensive activities of Clonidine.
Tiotropium	The metabolism of Clonidine can be decreased when combined with Tiotropium.
Tipranavir	The metabolism of Clonidine can be decreased when combined with Tipranavir.
Tizanidine	The risk or severity of adverse effects can be increased when Tizanidine is combined with Clonidine.
Tocainide	The metabolism of Clonidine can be decreased when combined with Tocainide.
Tocilizumab	The metabolism of Clonidine can be increased when combined with Tocilizumab.
Tofacitinib	Clonidine may increase the bradycardic activities of Tofacitinib.
Tolazoline	The risk or severity of hypotension can be increased when Clonidine is combined with Tolazoline.
Tolcapone	The risk or severity of sedation can be increased when Clonidine is combined with Tolcapone.
Tolfenamic acid	The therapeutic efficacy of Clonidine can be decreased when used in combination with Tolfenamic acid.
Tolmetin	The therapeutic efficacy of Clonidine can be decreased when used in combination with Tolmetin.
Tolterodine	The metabolism of Clonidine can be decreased when combined with Tolterodine.
Topiramate	The risk or severity of sedation can be increased when Clonidine is combined with Topiramate.
Torasemide	The risk or severity of hypotension can be increased when Clonidine is combined with Torasemide.
Tovorafenib	The metabolism of Clonidine can be increased when combined with Tovorafenib.
Trabectedin	The metabolism of Trabectedin can be decreased when combined with Clonidine.
Tramadol	The risk or severity of sedation can be increased when Clonidine is combined with Tramadol.
Trandolapril	The risk or severity of hypotension can be increased when Clonidine is combined with Trandolapril.
Tranylcypromine	The risk or severity of sedation can be increased when Clonidine is combined with Tranylcypromine.
Trastuzumab emtansine	The metabolism of Trastuzumab emtansine can be decreased when combined with Clonidine.
Trazodone	The risk or severity of sedation can be increased when Clonidine is combined with Trazodone.
Treprostinil	The risk or severity of hypotension can be increased when Clonidine is combined with Treprostinil.
Tretinoin	The risk or severity of elevated intracranial pressure can be increased when Clonidine is combined with Tretinoin.
Triamcinolone	The metabolism of Clonidine can be increased when combined with Triamcinolone.
Triamterene	The metabolism of Clonidine can be decreased when combined with Triamterene.
Triazolam	The risk or severity of sedation can be increased when Clonidine is combined with Triazolam.
Trichlormethiazide	The risk or severity of hypotension can be increased when Clonidine is combined with Trichlormethiazide.
Trichloroethylene	The risk or severity of sedation can be increased when Clonidine is combined with Trichloroethylene.
Triclabendazole	The serum concentration of Clonidine can be increased when it is combined with Triclabendazole.
Triclofos	The risk or severity of sedation can be increased when Clonidine is combined with Triclofos.
Trifluoperazine	The risk or severity of sedation can be increased when Clonidine is combined with Trifluoperazine.
Triflupromazine	The risk or severity of sedation can be increased when Clonidine is combined with Triflupromazine.
Trihexyphenidyl	The risk or severity of Tachycardia can be increased when Trihexyphenidyl is combined with Clonidine.
Trilaciclib	The metabolism of Clonidine can be increased when combined with Trilaciclib.
Trimebutine	Clonidine may increase the atrioventricular blocking (AV block) activities of Trimebutine.
Trimethadione	The risk or severity of sedation can be increased when Clonidine is combined with Trimethadione.
Trimethaphan	The risk or severity of hypotension can be increased when Clonidine is combined with Trimethaphan.
Trimethobenzamide	The risk or severity of sedation can be increased when Clonidine is combined with Trimethobenzamide.
Trimipramine	The risk or severity of sedation can be increased when Clonidine is combined with Trimipramine.
Tripelennamine	The metabolism of Clonidine can be decreased when combined with Tripelennamine.
Triprolidine	The risk or severity of sedation can be increased when Clonidine is combined with Triprolidine.
Trofinetide	The metabolism of Clonidine can be decreased when combined with Trofinetide.
Troglitazone	The metabolism of Clonidine can be increased when combined with Troglitazone.
Troleandomycin	The metabolism of Clonidine can be decreased when combined with Troleandomycin.
Tropisetron	The risk or severity of sedation can be increased when Clonidine is combined with Tropisetron.
Trospium	The metabolism of Clonidine can be decreased when combined with Trospium.
Trovafloxacin	The metabolism of Clonidine can be decreased when combined with Trovafloxacin.
Tryptophan	The risk or severity of sedation can be increased when Clonidine is combined with Tryptophan.
Tubocurarine	The risk or severity of sedation can be increased when Clonidine is combined with Tubocurarine.
Tucatinib	The metabolism of Tucatinib can be decreased when combined with Clonidine.
Udenafil	The metabolism of Clonidine can be decreased when combined with Udenafil.
Umeclidinium	The metabolism of Clonidine can be decreased when combined with Umeclidinium.
Unoprostone	Clonidine may increase the hypotensive activities of Unoprostone.
Urethane	The risk or severity of sedation can be increased when Clonidine is combined with Urethane.
Vadadustat	The serum concentration of Clonidine can be increased when it is combined with Vadadustat.
Valbenazine	The metabolism of Clonidine can be decreased when combined with Valbenazine.
Valdecoxib	The therapeutic efficacy of Clonidine can be decreased when used in combination with Valdecoxib.
Valproic acid	The risk or severity of sedation can be increased when Clonidine is combined with Valproic acid.
Valsartan	The risk or severity of hypotension can be increased when Clonidine is combined with Valsartan.
Vardenafil	The metabolism of Clonidine can be decreased when combined with Vardenafil.
Vecuronium	The risk or severity of sedation can be increased when Clonidine is combined with Vecuronium.
Vemurafenib	The serum concentration of Clonidine can be increased when it is combined with Vemurafenib.
Venetoclax	The metabolism of Clonidine can be decreased when combined with Venetoclax.
Venlafaxine	The risk or severity of sedation can be increased when Clonidine is combined with Venlafaxine.
Verapamil	Verapamil may increase the atrioventricular blocking (AV block) activities of Clonidine.
Vericiguat	The risk or severity of adverse effects can be increased when Clonidine is combined with Vericiguat.
Vernakalant	The metabolism of Clonidine can be decreased when combined with Vernakalant.
Vigabatrin	The risk or severity of sedation can be increased when Clonidine is combined with Vigabatrin.
Vilanterol	Vilanterol may decrease the antihypertensive activities of Clonidine.
Vilazodone	The risk or severity of sedation can be increased when Clonidine is combined with Vilazodone.
Viloxazine	The risk or severity of sedation can be increased when Clonidine is combined with Viloxazine.
Vinblastine	The metabolism of Clonidine can be increased when combined with Vinblastine.
Vincristine	The metabolism of Clonidine can be decreased when combined with Vincristine.
Vinorelbine	The metabolism of Clonidine can be decreased when combined with Vinorelbine.
Vitamin E	The metabolism of Clonidine can be increased when combined with Vitamin E.
Vonoprazan	The metabolism of Clonidine can be decreased when combined with Vonoprazan.
Vorapaxar	The metabolism of Clonidine can be decreased when combined with Vorapaxar.
Voriconazole	The metabolism of Clonidine can be decreased when combined with Voriconazole.
Vortioxetine	The risk or severity of sedation can be increased when Clonidine is combined with Vortioxetine.
Voxelotor	The serum concentration of Clonidine can be increased when it is combined with Voxelotor.
Voxilaprevir	The metabolism of Voxilaprevir can be decreased when combined with Clonidine.
Warfarin	The metabolism of Clonidine can be increased when combined with Warfarin.
Xamoterol	Xamoterol may decrease the antihypertensive activities of Clonidine.
Xylometazoline	Clonidine may increase the atrioventricular blocking (AV block) activities of Xylometazoline.
Yohimbine	The risk or severity of sedation can be increased when Clonidine is combined with Yohimbine.
Zafirlukast	The serum concentration of Clonidine can be increased when it is combined with Zafirlukast.
Zaleplon	The risk or severity of sedation can be increased when Clonidine is combined with Zaleplon.
Ziconotide	The risk or severity of sedation can be increased when Clonidine is combined with Ziconotide.
Zileuton	The metabolism of Clonidine can be decreased when combined with Zileuton.
Zimelidine	The risk or severity of sedation can be increased when Clonidine is combined with Zimelidine.
Ziprasidone	The risk or severity of sedation can be increased when Clonidine is combined with Ziprasidone.
Zofenopril	The risk or severity of hypotension can be increased when Clonidine is combined with Zofenopril.
Zolmitriptan	The risk or severity of sedation can be increased when Clonidine is combined with Zolmitriptan.
Zolpidem	The risk or severity of sedation can be increased when Clonidine is combined with Zolpidem.
Zonisamide	The risk or severity of sedation can be increased when Clonidine is combined with Zonisamide.
Zopiclone	The risk or severity of sedation can be increased when Clonidine is combined with Zopiclone.
Zotepine	The risk or severity of sedation can be increased when Clonidine is combined with Zotepine.
Zuclopenthixol	The risk or severity of sedation can be increased when Clonidine is combined with Zuclopenthixol.
Zuranolone	The risk or severity of sedation can be increased when Clonidine is combined with Zuranolone.

Food Interactions

• Avoid alcohol.
• Take with or without food. The absorption is unaffected by food.

Products

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Product Ingredients

Ingredient	UNII	CAS	InChI Key
Clonidine hydrochloride	W76I6XXF06	4205-91-8	ZNIFSRGNXRYGHF-UHFFFAOYSA-N

Product Images

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International/Other Brands

Catapresan (Boehringer Ingelheim) / Catapressan (Boehringer Ingelheim) / Catarpres-TTS / Dixarit (Boehringer Ingelheim) / Isoglaucon (Agepha) / Run Rui (Bausch & Lomb) / Velaril (Roemmers) / Winpress (Winston)

Brand Name Prescription Products

Name	Dosage	Strength	Route	Labeller	Marketing Start	Marketing End	Region	Image
Catapres	Tablet	0.100 mg/1	Oral	Physicians Total Care, Inc.	1974-09-03	2011-06-30
Catapres	Tablet	0.300 mg/1	Oral	Boehringer Ingelheim Pharmaceuticals Inc.	1999-05-01	Not applicable
Catapres	Patch, extended release	0.1 mg/24h	Transdermal	Physicians Total Care, Inc.	1994-12-09	2012-06-30
Catapres	Tablet	0.200 mg/1	Oral	Boehringer Ingelheim Promeco s.a. De c.v.	1999-05-01	2013-03-25
Catapres	Tablet	0.1 mg/1	Oral	REMEDYREPACK INC.	2016-10-11	2018-01-09
Catapres	Tablet	0.200 mg/1	Oral	Boehringer Ingelheim Pharmaceuticals Inc.	1999-05-01	Not applicable
Catapres	Patch, extended release	0.1 mg/24h	Transdermal	Rebel Distributors	1985-10-01	Not applicable
Catapres	Patch, extended release	0.3 mg/24h	Transdermal	Physicians Total Care, Inc.	2004-07-08	2012-06-30
Catapres	Tablet	0.100 mg/1	Oral	Boehringer Ingelheim Promeco s.a. De c.v.	1999-05-01	2013-03-25
Catapres	Tablet	0.200 mg/1	Oral	Physicians Total Care, Inc.	1974-09-03	2011-06-30
Catapres	Patch, extended release	0.2 mg/24h	Transdermal	Physicians Total Care, Inc.	1994-10-11	2011-06-30
Catapres	Tablet	0.100 mg/1	Oral	Boehringer Ingelheim Pharmaceuticals Inc.	1999-05-01	Not applicable
Catapres	Tablet	.300 mg/1	Oral	Boehringer Ingelheim Promeco s.a. De c.v.	1999-05-01	2013-03-25
Catapres Tab 0.1mg	Tablet	0.1 mg	Oral	Boehringer Ingelheim (Canada) Ltd Ltee	1973-12-31	2017-02-15
Catapres Tab 0.2mg	Tablet	0.2 mg	Oral	Boehringer Ingelheim (Canada) Ltd Ltee	1974-12-31	2015-03-30
Catapres-TTS	Patch	0.1 mg/1d	Transdermal	Boehringer Ingelheim Pharmaceuticals Inc.	1985-10-01	2023-12-31
Catapres-TTS	Patch	0.3 mg/1d	Transdermal	Boehringer Ingelheim Pharmaceuticals Inc.	1985-10-01	2023-12-31
Catapres-TTS	Patch	0.2 mg/1d	Transdermal	Boehringer Ingelheim Pharmaceuticals Inc.	1985-10-01	2023-12-31
Catapres-TTS-1	Patch	0.1 mg/1d	Transdermal	Technomed Inc.	2022-03-01	2026-10-30
Catapres-TTS-2	Patch	0.2 mg/1d	Transdermal	Technomed Inc.	2022-03-01	2026-10-30
Catapres-TTS-3	Patch	0.3 mg/1d	Transdermal	Technomed Inc.	2022-03-01	2026-10-30
Clonidine	Tablet	0.025 mg	Oral	Sivem Pharmaceuticals Ulc	2024-02-02	Not applicable
Clonidine	Tablet	0.025 mg	Oral	Sanis Health Inc	2011-02-08	2012-08-03
Clonidine	Tablet	0.2 mg	Oral	Sanis Health Inc	2011-02-08	2012-08-03
Clonidine	Tablet	0.2 mg	Oral	Sivem Pharmaceuticals Ulc	2024-02-02	Not applicable
Clonidine	Tablet	0.1 mg	Oral	Sanis Health Inc	2011-02-08	2012-08-03
Clonidine	Tablet	0.1 mg	Oral	Sivem Pharmaceuticals Ulc	2024-02-02	Not applicable
Clonidine 0.1	Tablet	0.1 mg	Oral	Pro Doc Limitee	1991-12-31	2014-07-24
Clonidine HCl Tab 0.2mg	Tablet	.2 mg	Oral	Pro Doc Limitee	1991-12-31	2014-07-24
Clonidine Hydrochloride	Tablet	0.200 mg/1	Oral	Vintage Pharmaceuticals, LLC	2007-05-11	2007-05-11
Clonidine Hydrochloride	Tablet	0.100 mg/1	Oral	Vintage Pharmaceuticals, LLC	2007-05-11	2007-05-11
Clonidine Hydrochloride	Tablet	0.300 mg/1	Oral	Vintage Pharmaceuticals, LLC	2007-05-11	2007-05-11
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	State of Florida DOH Central Pharmacy	2009-06-20	Not applicable
Clonidine hydrochloride extended-release	Tablet, extended release	0.1 mg/1	Oral	Concordia Pharmaceuticals, Inc	2010-12-09	2017-03-31
Clonidine Transdermal System USP, 0.1 mg/day	Patch	0.1 mg/1d	Transdermal	Trupharma, Llc	2023-06-30	Not applicable
Clonidine Transdermal System USP, 0.2 mg/day	Patch	0.2 mg/1d	Transdermal	Trupharma, Llc	2023-06-30	Not applicable
Clonidine Transdermal System USP, 0.3 mg/day	Patch	0.3 mg/1d	Transdermal	Trupharma, Llc	2023-06-30	Not applicable
Dixarit Tab 0.025mg	Tablet	0.025 mg	Oral	Boehringer Ingelheim (Canada) Ltd Ltee	1981-12-31	2016-10-22
Duraclon	Injection, solution	0.5 mg/1mL	Intravenous	Xanodyne Pharmaceuticals	2013-05-13	2013-05-23
Duraclon	Injection, solution	0.1 mg/1mL	Epidural	Mylan Institutional LLC	1997-01-26	Not applicable
Duraclon	Injection, solution	0.1 mg/1mL	Intravenous	Xanodyne Pharmaceuticals	2013-05-13	2013-05-23
Duraclon	Injection, solution	0.5 mg/1mL	Intravenous	Bioniche Pharma USA LLC	2010-09-08	2010-09-10
Kapvay	Tablet, extended release	0.1 mg/1	Oral	Shionogi Pharma, Inc.	2010-12-09	2010-12-16
Kapvay	Tablet, extended release	0.2 mg/1	Oral	Shionogi	2010-12-09	2014-08-31
Kapvay	Tablet, extended release	0.2 mg/1	Oral	Concordia Pharmaceuticals Inc.	2010-12-09	2014-11-27
Kapvay	Tablet, extended release	0.1 mg/1	Oral	Shionogi	2010-12-09	2014-04-30
Kapvay	Tablet, extended release	0.1 mg/1	Oral	Concordia Pharmaceuticals Inc.	2010-12-09	Not applicable
Nexiclon	Tablet, extended release	0.17 mg/1	Oral	Tris Pharma, Inc.	2010-12-17	2016-11-18
Nexiclon XR	Tablet, extended release	0.17 mg/1	Oral	Next Wave Pharmaceuticals, Inc.	2010-12-15	2012-11-30
Nexiclon XR	Tablet, extended release	0.26 mg/1	Oral	Tris Pharma, Inc.	2010-12-17	2016-11-18
Nexiclon XR	Tablet, extended release	0.17 mg/1	Oral	Athena Bioscience, LLC	2022-03-01	Not applicable
Nexiclon XR	Suspension, extended release	0.09 mg/1mL	Oral	Next Wave Pharmaceuticals, Inc.	2010-12-15	2012-10-31
Nexiclon XR	For suspension, extended release	0.09 mg/1mL	Oral	Tris Pharma, Inc.	2010-12-17	2016-11-18
Nexiclon XR	Tablet, extended release	0.26 mg/1	Oral	Next Wave Pharmaceuticals, Inc.	2010-12-15	2012-11-30

Generic Prescription Products

Name	Dosage	Strength	Route	Labeller	Marketing Start	Marketing End	Region	Image
Apo-clonidine	Tablet	0.025 mg	Oral	Apotex Corporation	2004-07-13	Not applicable
Apo-clonidine Tab 0.1mg	Tablet	0.1 mg	Oral	Apotex Corporation	1990-12-31	Not applicable
Apo-clonidine Tab 0.2mg	Tablet	0.2 mg	Oral	Apotex Corporation	1990-12-31	Not applicable
Clonidine	Patch, extended release	0.3 mg/24h	Transdermal	Teva	2010-08-25	2018-03-31
Clonidine	Patch, extended release	0.3 mg/24h	Transdermal	Mayne Pharma Inc.	2016-08-03	Not applicable
Clonidine	Patch	0.3 mg/1d	Transdermal	Mylan Pharmaceuticals Inc.	2013-03-01	Not applicable
Clonidine	Patch	0.1 mg/1d	Transdermal	Physicians Total Care, Inc.	2011-09-24	Not applicable
Clonidine	Patch, extended release	0.2 mg/24h	Transdermal	Dr. Reddy's Labratories Inc.	2024-02-10	Not applicable
Clonidine	Patch	0.3 mg/1d	Transdermal	Par Pharmaceutical	2009-08-20	2012-05-31
Clonidine	Patch, extended release	0.2 mg/24h	Transdermal	Lake Erie Medical Dba Quality Care Produts Llc	2010-08-25	2016-06-01
Clonidine	Patch, extended release	0.2 mg/24h	Transdermal	Teva	2010-08-25	2018-01-31
Clonidine	Patch, extended release	0.1 mg/24h	Transdermal	Corium International, Inc.	2016-08-03	Not applicable
Clonidine	Patch	0.2 mg/1d	Transdermal	Mylan Pharmaceuticals Inc.	2013-03-04	Not applicable
Clonidine	Tablet, extended release	0.17 mg/1	Oral	Palmetto Pharmaceuticals Inc.	2022-03-01	Not applicable
Clonidine	Injection, solution	500 ug/1mL	Epidural	XGen Pharmaceuticals DJB, Inc.	2013-10-29	Not applicable
Clonidine	Patch, extended release	0.3 mg/24h	Transdermal	Corium International, Inc.	2016-08-03	Not applicable
Clonidine	Patch, extended release	0.2 mg/24h	Transdermal	Mayne Pharma Inc.	2016-08-03	Not applicable
Clonidine	Patch	0.3 mg/1d	Transdermal	Physicians Total Care, Inc.	2011-05-10	Not applicable
Clonidine	Patch, extended release	0.1 mg/24h	Transdermal	Dr. Reddy's Labratories Inc.	2024-02-10	Not applicable
Clonidine	Patch	0.2 mg/1d	Transdermal	Par Pharmaceutical	2009-08-20	2012-06-30
Clonidine	Patch, extended release	0.1 mg/24h	Transdermal	Teva	2010-08-25	2018-04-30
Clonidine	Patch, extended release	0.1 mg/24h	Transdermal	Mayne Pharma Inc.	2016-08-03	Not applicable
Clonidine	Patch	0.2 mg/1d	Transdermal	Physicians Total Care, Inc.	2010-12-14	Not applicable
Clonidine	Patch	0.1 mg/1d	Transdermal	Mylan Pharmaceuticals Inc.	2013-02-25	Not applicable
Clonidine	Injection, solution	500 ug/1mL	Epidural	Fresenius Kabi USA, LLC	2011-07-08	2016-11-07
Clonidine	Injection, solution	100 ug/1mL	Epidural	XGen Pharmaceuticals DJB, Inc.	2013-10-29	Not applicable
Clonidine	Patch, extended release	0.2 mg/24h	Transdermal	Corium International, Inc.	2016-08-03	Not applicable
Clonidine	Patch	0.2 mg/1d	Transdermal	Lake Erie Medical Dba Quality Care Produts Llc	2013-02-08	2015-12-31
Clonidine	Patch	0.1 mg/1d	Transdermal	Par Pharmaceutical	2009-08-20	2012-06-30
Clonidine	Patch, extended release	0.3 mg/24h	Transdermal	Dr. Reddy's Labratories Inc.	2024-02-10	Not applicable
Clonidine	Tablet, extended release	0.1 mg/1	Oral	Ingenus Pharmaceuticals, LLC	2019-03-05	Not applicable
Clonidine	Tablet	0.1 mg/1	Oral	Stat Rx USA	1986-12-16	Not applicable
Clonidine	Tablet, extended release	0.17 mg/1	Oral	Trupharma, Llc	2024-01-11	Not applicable
Clonidine Hci	Injection, solution	100 ug/1mL	Intravenous	HF Acquisition Co LLC, DBA HealthFirst	2018-12-23	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Denton Pharma, Inc. Dba Northwind Pharmaceuticals	2020-04-14	2023-07-31
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Mylan Pharmaceuticals Inc.	1987-06-09	2020-09-30
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Golden State Medical Supply, Inc.	2017-01-03	2017-10-10
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Impax Generics	2009-12-01	2016-11-14
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Major Pharmaceuticals	2006-11-20	2021-03-31
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	A S Medication Solutions	2013-02-04	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	A-S Medication Solutions	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Pd Rx Pharmaceuticals, Inc.	2013-06-17	2018-01-19
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Preferred Pharmaceuticals, Inc.	2015-04-13	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	General Injectables & Vaccines, Inc	2010-03-01	2021-03-31
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	PD-Rx Pharmaceuticals, Inc.	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.100 mg/1	Oral	State of Florida DOH Central Pharmacy	2009-07-01	Not applicable
Clonidine hydrochloride	Tablet	0.3 mg/1	Oral	Aphena Pharma Solutions - Tennessee, LLC	2017-06-01	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Cardinal Health	2011-07-08	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Clinical Solutions Wholsesale	2007-03-09	2017-06-23
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Preferred Pharmaceuticals, Inc.	2011-11-10	2019-08-08
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Mutual Pharmaceutical	1987-09-04	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	bryant ranch prepack	2020-07-01	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	REMEDYREPACK INC.	2021-12-14	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	bryant ranch prepack	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	PD-Rx Pharmaceuticals, Inc.	1987-06-09	2019-06-17
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Lake Erie Medical DBA Quality Care Products LLC	1995-01-03	2019-10-11
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Northwind Pharmaceuticals, LLC	2015-02-25	Not applicable
Clonidine hydrochloride	Tablet	0.2 mg/1	Oral	Asclemed Usa, Inc.	2017-06-01	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	A-S Medication Solutions	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	REMEDYREPACK INC.	2015-07-31	2017-12-28
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Remedy Repack	2010-07-16	2014-06-18
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Physicians Total Care, Inc.	2001-10-03	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	bryant ranch prepack	2020-07-01	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Remedy Repack	2012-08-16	2017-06-15
Clonidine Hydrochloride	Tablet, extended release	0.2 mg/1	Oral	Actavis Pharma, Inc.	2015-06-17	2015-06-17
Clonidine hydrochloride	Tablet	0.1 mg/1	Oral	Trupharma, Llc	2017-06-01	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	McKesson Corporation dba SKY Packaging	1995-01-03	2021-08-31
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	State of Florida DOH Central Pharmacy	2009-07-01	Not applicable
Clonidine hydrochloride	Tablet	0.3 mg/1	Oral	bryant ranch prepack	2017-06-01	Not applicable
Clonidine Hydrochloride	Tablet, extended release	0.1 mg/1	Oral	bryant ranch prepack	2015-06-17	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Nucare Pharmaceuticals,inc.	1987-09-04	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Directrx	2015-01-01	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Northwind Pharmaceuticals	2014-09-24	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	bryant ranch prepack	2020-07-01	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Nucare Pharmaceuticals,inc.	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	St. Mary's Medical Park Pharmacy	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	REMEDYREPACK INC.	2017-03-01	2018-07-28
Clonidine Hydrochloride	Tablet	0.300 mg/1	Oral	bryant ranch prepack	2007-03-09	2017-12-31
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	H. J. Harkins Company Inc.	2017-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.200 mg/1	Oral	Aidarex Pharmaceuticals LLC	2007-03-09	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	bryant ranch prepack	2020-07-01	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	REMEDYREPACK INC.	2019-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Preferred Pharmaceuticals, Inc.	2011-11-10	2019-08-09
Clonidine Hydrochloride	Tablet	0.200 mg/1	Oral	Qualitest	2007-03-09	2017-07-31
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	A-S Medication Solutions	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	bryant ranch prepack	2020-07-01	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Amerincan Health Packaging	2005-06-08	2017-06-30
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Directrx	2019-04-04	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	bryant ranch prepack	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Contract Pharmacy Services Pa	2010-08-18	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Alembic Pharmaceuticals Limited	2016-05-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Method Pharmaceuticals, LLC	2020-07-01	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	McKesson Packaging Services Business Unit of McKesson Corporation	2007-09-05	2010-03-01
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Remedy Repack	2015-07-22	2016-10-29
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	General Injectables & Vaccines, Inc.	2019-10-10	2020-09-30
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Directrx	2015-01-01	Not applicable
Clonidine Hydrochloride	Tablet	0.100 mg/1	Oral	A S Medication Solutions	2007-03-09	Not applicable
Clonidine hydrochloride	Tablet	0.2 mg/1	Oral	Proficient Rx LP	2017-06-01	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	bryant ranch prepack	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Nucare Pharmaceuticals,inc.	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	St Marys Medical Park Pharmacy	2010-03-01	2018-06-30
Clonidine Hydrochloride	Tablet	0.100 mg/1	Oral	bryant ranch prepack	2007-03-09	2017-07-30
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Remedy Repack	2014-03-04	2015-12-11
Clonidine Hydrochloride	Tablet	0.100 mg/1	Oral	TYA Pharmaceuticals	2007-03-09	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Aurobindo Pharma Limited	2021-06-02	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	NCS HealthCare of KY, Inc dba Vangard Labs	2018-07-10	2020-05-31
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	PD-Rx Pharmaceuticals, Inc.	1987-06-09	2019-09-11
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Carlsbad Technology, Inc.	2013-06-17	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	REMEDYREPACK INC.	2018-11-07	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Med Pharma Co., Ltd.	2010-07-29	2012-11-08
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Unichem Pharmaceuticals (USA), Inc.	2020-12-24	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	American Health Packaging	2020-07-29	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	HF Acquisition Co LLC, DBA HealthFirst	2020-04-06	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Unichem Pharmaceuticals (USA), Inc.	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Preferred Pharmaceuticals Inc.	2021-10-05	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Nucare Pharmaceuticals,inc.	2016-05-03	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Mc Kesson Contract Packaging	2011-10-03	2017-09-30
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	bryant ranch prepack	1987-09-04	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Cardinal Health	2006-11-20	2021-03-31
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	RedPharm Drug, Inc.	2009-09-21	Not applicable
Clonidine Hydrochloride	Injection, solution	500 ug/1mL	Intravenous	Hikma Farmaceutica	2011-01-01	2011-01-01
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	AvPAK	2023-05-30	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Unit Dose Services	1987-09-04	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Actavis Pharma, Inc.	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Unit Dose Services	2009-09-21	2016-08-05
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	A-S Medication Solutions	2013-06-17	2018-03-31
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Remedy Repack	2010-07-15	2014-03-27
Clonidine Hydrochloride	Tablet	0.200 mg/1	Oral	State of Florida DOH Central Pharmacy	2014-01-01	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	A-S Medication Solutions	2020-12-24	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Mylan Institutional Inc.	1997-02-14	2020-09-30
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	bryant ranch prepack	2020-07-01	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	medsource pharmaceuticals	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.300 mg/1	Oral	A-S Medication Solutions	2007-03-09	2016-08-31
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	bryant ranch prepack	1995-01-03	2017-04-30
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Med Vantx, Inc.	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Marlex Pharmaceuticals Inc	2020-10-01	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	St. Marys Medical Park Pharmacy	2014-01-23	2017-09-30
Clonidine Hydrochloride	Tablet, extended release	0.1 mg/1	Oral	Lupin Pharmaceuticals, Inc.	2018-02-07	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Nucare Pharmaceuticals, Inc.	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	REMEDYREPACK INC.	2021-07-19	Not applicable
Clonidine Hydrochloride	Tablet	0.100 mg/1	Oral	Preferred Pharmaceuticals, Inc.	2014-10-22	2019-08-08
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	REMEDYREPACK INC.	2017-05-03	Not applicable
Clonidine hydrochloride	Tablet	0.3 mg/1	Oral	Trupharma, Llc	2017-06-01	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Northwind Pharmaceuticals	2021-02-05	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	A-S Medication Solutions	1995-01-03	2016-10-05
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Cardinal Health	2011-07-08	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	REMEDYREPACK INC.	2015-11-05	2018-08-29
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	REMEDYREPACK INC.	2009-01-16	2017-12-13
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Mutual Pharmaceutical	1987-09-04	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	bryant ranch prepack	2020-12-24	Not applicable
Clonidine Hydrochloride	Injection, solution	0.5 mg/1mL	Epidural	Zydus Lifesciences Limited	2018-01-31	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Med Pharma Co., Ltd.	2011-01-10	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	A-S Medication Solutions	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.200 mg/1	Oral	Unit Dose Services	2007-03-09	2017-12-31
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	DAVA Pharmaceuticals, Inc.	1988-04-05	2014-04-01
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Alembic Pharmaceuticals Inc.	2016-05-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Rebel Distributors	1987-09-04	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Rpk Pharmaceuticals, Inc.	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet, extended release	0.1 mg/1	Oral	Amneal Pharmaceuticals NY LLC	2017-11-29	Not applicable
Clonidine Hydrochloride	Tablet	0.200 mg/1	Oral	Solco Healthcare Llc	2023-01-05	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Cardinal Health 107, LLC	2020-07-30	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Preferred Pharmaceuticals, Inc.	2011-11-10	2019-08-08
Clonidine Hydrochloride	Tablet, extended release	0.1 mg/1	Oral	Jubilant Cadista Pharmaceuticals Inc.	2018-01-29	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Remedy Repack	2014-07-21	2017-06-29
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Preferred Pharmaceuticals Inc.	2018-09-24	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	bryant ranch prepack	2009-09-21	Not applicable
Clonidine hydrochloride	Tablet, extended release	0.1 mg/1	Oral	BluePoint Laboratories	2023-08-24	Not applicable
Clonidine hydrochloride	Tablet	0.1 mg/1	Oral	Nucare Pharmaceuticals,inc.	2017-06-01	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Cardinal Health	2009-09-03	2016-07-31
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	North Star Rx Llc	2013-02-04	2015-10-31
Clonidine HYDROCHLORIDE	Tablet	0.1 mg/1	Oral	Apotheca, Inc.	1996-12-21	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	bryant ranch prepack	2020-07-01	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Major Pharmaceuticals	2006-11-20	2021-02-28
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Richmond Pharmaceuticals	1987-09-04	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Clinical Solutions Wholesale, LLC	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	BluePoint Laboratories	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Lake Erie Medical DBA Quality Care Products LLC	2013-06-17	2019-12-31
Clonidine Hydrochloride	Tablet	.2 mg/1	Oral	Blenheim Pharmacal, Inc.	2013-11-15	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Proficient Rx LP	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Blenheim Pharmacal, Inc.	2010-04-08	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	bryant ranch prepack	2016-05-03	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Clinical Solutions Wholsesale	2007-03-09	2017-06-23
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	HF Acquisition Co LLC, DBA HealthFirst	2018-11-30	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Contract Pharmacy Services-PA	2020-01-09	Not applicable
Clonidine Hydrochloride	Injection, solution	100 ug/1mL	Epidural	Fresenius Kabi USA, LLC	2011-07-08	2016-11-07
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Pd Rx Pharmaceuticals, Inc.	2013-06-17	2018-01-18
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Remedy Repack	2009-12-02	2014-10-03
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	REMEDYREPACK INC.	2017-03-22	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Mylan Institutional Inc.	1995-06-12	2020-02-29
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Mylan Pharmaceuticals Inc.	1987-06-09	2020-09-30
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	McKesson Packaging Services Business Unit of McKesson Corporation	2007-06-12	2010-03-01
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Golden State Medical Supply, Inc.	2017-01-03	2020-01-29
Clonidine hydrochloride	Tablet	0.1 mg/1	Oral	A-S Medication Solutions	2017-06-01	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Impax Generics	2009-12-01	2016-11-14
Clonidine Hydrochloride	Tablet	0.100 mg/1	Oral	Dispensing Solutions, Inc.	2007-03-09	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Preferred Pharmaceuticals Inc.	2023-07-26	Not applicable
Clonidine hydrochloride	Tablet, extended release	0.1 mg/1	Oral	Quality Care Products, LLC	2019-10-11	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Physicians Total Care, Inc.	2004-11-30	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	NCS HealthCare of KY, LLC dba Vangard Labs	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	REMEDYREPACK INC.	2015-09-01	2018-02-07
Clonidine Hydrochloride	Tablet	.3 mg/1	Oral	Blenheim Pharmacal, Inc.	2011-04-01	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	PD-Rx Pharmaceuticals, Inc.	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	State of Florida DOH Central Pharmacy	2009-07-01	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	A-S Medication Solutions	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Remedy Repack	2015-06-15	2017-03-07
Clonidine Hydrochloride	Tablet, extended release	0.1 mg/1	Oral	REMEDYREPACK INC.	2021-11-28	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	bryant ranch prepack	2020-07-01	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Unit Dose Services	2009-09-21	2016-08-05
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Amerincan Health Packaging	2005-08-08	2016-12-31
Clonidine Hydrochloride	Tablet, extended release	0.1 mg/1	Oral	Actavis Pharma, Inc.	2015-06-17	Not applicable
Clonidine Hydrochloride	Injection, solution	0.5 mg/1mL	Epidural	Zydus Pharmaceuticals USA Inc.	2018-01-31	Not applicable
Clonidine Hydrochloride	Injection, solution	100 ug/1mL	Intravenous	Hikma Farmaceutica	2011-01-01	2011-01-01
Clonidine hydrochloride	Tablet	0.1 mg/1	Oral	Asclemed Usa, Inc.	2017-06-01	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	A-S Medication Solutions	2020-12-24	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	A-S Medication Solutions	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Mc Kesson Contract Packaging	1995-01-03	2017-09-30
Clonidine Hydrochloride	Injection, solution	500 ug/1mL	Epidural	AMERICAN REGENT, INC.	2010-04-15	2016-03-30
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	REMEDYREPACK INC.	2017-12-12	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Remedy Repack	2015-07-14	2016-07-14
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	AvPAK	2023-05-30	Not applicable
Clonidine Hydrochloride	Tablet, extended release	0.1 mg/1	Oral	REMEDYREPACK INC.	2019-05-23	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Rpk Pharmaceuticals, Inc.	2016-05-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Lake Erie Medical DBA Quality Care Products LLC	2010-05-19	2014-06-01
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Aidarex Pharmaceuticals LLC	1987-09-04	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Alembic Pharmaceuticals Limited	2016-05-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	State of Florida DOH Central Pharmacy	2009-07-01	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Method Pharmaceuticals, LLC	2020-07-01	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Cardinal Health	2013-06-17	2015-12-15
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	RedPharm Drug, Inc.	2018-01-01	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	REMEDYREPACK INC.	2018-02-27	2020-05-11
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Amerincan Health Packaging	2015-10-01	2018-02-28
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	North Star Rx Llc	2013-02-04	2015-10-31
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	St. Mary's Medical Park Pharmacy	2018-03-02	Not applicable
Clonidine Hydrochloride	Injection, solution	0.1 mg/1mL	Epidural	Zydus Lifesciences Limited	2018-01-31	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Med Pharma Co., Ltd.	2011-01-10	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Aurobindo Pharma Limited	2021-06-02	Not applicable
Clonidine hydrochloride	Tablet	0.1 mg/1	Oral	Proficient Rx LP	2017-06-01	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Proficient Rx LP	1987-09-04	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Lake Erie Medical Dba Quality Care Produts Llc	2008-06-01	2016-06-01
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Lake Erie Medical DBA Quality Care Products LLC	1995-01-03	2019-10-11
Clonidine hydrochloride	Tablet, extended release	0.1 mg/1	Oral	Ajanta Pharma USA Inc.	2017-11-21	Not applicable
Clonidine Hydrochloride	Tablet	0.100 mg/1	Oral	Qualitest	2007-03-09	2018-09-23
Clonidine hydrochloride	Tablet	0.1 mg/1	Oral	Northwind Pharmaceuticals	2020-10-01	Not applicable
Clonidine hydrochloride	Tablet, extended release	0.1 mg/1	Oral	American Health Packaging	2019-11-01	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Med Pharma Co., Ltd.	2010-07-29	2012-11-08
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Denton Pharma, Inc. Dba Northwind Pharmaceuticals	2019-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	bryant ranch prepack	2020-07-01	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Actavis Pharma, Inc.	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	REMEDYREPACK INC.	2016-04-11	2017-04-11
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Cardinal Health	1986-12-16	2012-10-31
Clonidine Hydrochloride	Injection, solution	500 ug/1mL	Epidural	Pharma Force, Inc.	2009-10-16	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	REMEDYREPACK INC.	2019-03-14	Not applicable
Clonidine hydrochloride	Tablet	0.2 mg/1	Oral	A-S Medication Solutions	2017-06-01	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Cardinal Health	2009-09-03	2014-05-30
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	bryant ranch prepack	2016-05-03	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Golden State Medical Supply, Inc.	2017-01-03	2017-10-10
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Remedy Repack	2015-01-29	2016-08-13
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Impax Generics	2009-12-01	2016-11-14
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	NCS HealthCare of KY, LLC dba Vangard Labs	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Major Pharmaceuticals	2006-11-20	2020-07-31
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Richmond Pharmaceuticals	1987-09-04	Not applicable
Clonidine hydrochloride	Tablet	0.2 mg/1	Oral	Northwind Pharmaceuticals	2022-04-15	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Cardinal Health 107, LLC	2020-07-29	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	NCS HealthCare of KY, Inc dba Vangard Labs	2009-09-21	2020-11-30
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Pd Rx Pharmaceuticals, Inc.	2013-06-17	2018-01-19
Clonidine hydrochloride	Tablet	0.1 mg/1	Oral	REMEDYREPACK INC.	2018-07-03	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Preferred Pharmaceuticals Inc.	2016-08-31	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Carlsbad Technology, Inc.	2013-06-17	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	bryant ranch prepack	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Stat Rx USA	2009-09-03	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Mylan Pharmaceuticals Inc.	1987-06-09	2020-09-30
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Marlex Pharmaceuticals Inc	2020-10-01	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	A-S Medication Solutions	2013-06-17	2018-03-31
Clonidine Hydrochloride	Tablet	0.300 mg/1	Oral	State of Florida DOH Central Pharmacy	2013-01-01	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	A-S Medication Solutions	2020-12-24	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Unichem Pharmaceuticals (USA), Inc.	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	A-S Medication Solutions	2016-05-03	2018-02-28
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Remedy Repack	2014-11-06	2015-11-20
Clonidine hydrochloride	Tablet	0.1 mg/1	Oral	bryant ranch prepack	2017-06-01	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Cardinal Health	2011-07-08	2019-04-30
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Remedy Repack	2015-11-04	2017-04-06
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Aidarex Pharmaceuticals LLC	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet, extended release	0.1 mg/1	Oral	NorthStar Rx LLC	2018-06-18	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	REMEDYREPACK INC.	2019-07-10	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Physicians Total Care, Inc.	1995-01-09	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Preferred Pharmaceuticals Inc.	2022-04-04	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	bryant ranch prepack	2020-07-01	Not applicable
Clonidine Hydrochloride	Injection, solution	500 ug/1mL	Intravenous	Hikma Pharmaceuticals USA Inc.	2011-01-01	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Remedy Repack	2015-03-17	2016-04-16
Clonidine Hydrochloride	Tablet	0.200 mg/1	Oral	A-S Medication Solutions	2007-03-09	2016-12-31
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Preferred Pharmaceuticals Inc.	2018-04-23	Not applicable
Clonidine hydrochloride	Tablet	0.3 mg/1	Oral	Asclemed Usa, Inc.	2017-06-01	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	PD-Rx Pharmaceuticals, Inc.	1987-06-09	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Rebel Distributors	1987-09-04	Not applicable
Clonidine hydrochloride	Tablet	0.1 mg/1	Oral	Quality Care Products, LLC	2017-06-01	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Rpk Pharmaceuticals, Inc.	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	PD-Rx Pharmaceuticals, Inc.	1987-06-09	2019-09-12
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	PD-Rx Pharmaceuticals, Inc.	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Mutual Pharmaceutical	1987-09-04	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	A-S Medication Solutions	2021-06-02	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Nucare Pharmaceuticals, Inc.	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	REMEDYREPACK INC.	2019-01-30	2020-06-01
Clonidine hydrochloride	Tablet	0.2 mg/1	Oral	Trupharma, Llc	2017-06-01	Not applicable
Clonidine Hydrochloride	Tablet, extended release	0.1 mg/1	Oral	Xiamen Lp Pharmaceutical Co., Ltd.	2017-12-01	Not applicable
Clonidine Hydrochloride	Tablet	0.300 mg/1	Oral	Qualitest	2007-03-09	2017-07-31
Clonidine Hydrochloride	Tablet, extended release	0.1 mg/1	Oral	Solco Healthcare Llc	2018-02-15	Not applicable
Clonidine Hydrochloride	Tablet	0.100 mg/1	Oral	Solco Healthcare Llc	2023-01-05	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	bryant ranch prepack	2020-07-01	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	BluePoint Laboratories	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Amerincan Health Packaging	2005-08-08	2017-03-31
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Unit Dose Services	1995-01-03	2017-12-31
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Directrx	2015-12-29	2023-12-31
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	DAVA Pharmaceuticals, Inc.	1988-04-05	2014-04-01
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Alembic Pharmaceuticals Inc.	2016-05-03	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Contract Pharmacy Services Pa	2010-07-29	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Nucare Pharmaceuticals, Inc.	2009-09-21	Not applicable
Clonidine hydrochloride	Tablet	0.3 mg/1	Oral	Denton Pharma, Inc. Dba Northwind Pharmaceuticals	2020-05-28	2023-01-31
Clonidine Hydrochloride	Injection, solution	100 ug/1mL	Epidural	AMERICAN REGENT, INC.	2010-04-15	2015-02-26
Clonidine Hydrochloride	Tablet	0.200 mg/1	Oral	A S Medication Solutions	2007-03-09	Not applicable
Clonidine Hydrochloride	Tablet, extended release	0.1 mg/1	Oral	bryant ranch prepack	2018-02-15	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Clinical Solutions Wholesale, LLC	2009-09-21	2018-12-01
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	PD-Rx Pharmaceuticals, Inc.	1987-09-04	2018-08-28
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Remedy Repack	2012-11-30	2014-04-01
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	bryant ranch prepack	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Nucare Pharmaceuticals,inc.	2016-05-03	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Clinical Solutions Wholsesale	2007-03-09	2017-06-23
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Remedy Repack	2015-02-11	2016-02-11
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Proficient Rx LP	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	REMEDYREPACK INC.	2018-11-27	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Med Pharma Co., Ltd.	2010-07-29	2012-11-08
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Nucare Pharmaceuticals,inc.	2020-07-01	Not applicable
Clonidine Hydrochloride	Tablet, extended release	0.1 mg/1	Oral	bryant ranch prepack	2018-02-15	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	A-S Medication Solutions	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	American Health Packaging	2020-07-30	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	A-S Medication Solutions	1987-09-04	2018-06-30
Clonidine Hydrochloride	Tablet, extended release	0.1 mg/1	Oral	Upsher-Smith Laboratories, LLC	2018-10-12	2021-06-30
Clonidine Hydrochloride	Tablet	.1 mg/1	Oral	Blenheim Pharmacal, Inc.	2013-11-15	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Aurobindo Pharma Limited	2021-06-02	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	REMEDYREPACK INC.	2019-01-23	Not applicable
Clonidine Hydrochloride	Tablet	0.200 mg/1	Oral	State of Florida DOH Central Pharmacy	2009-07-01	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Nucare Pharmaceuticals,inc.	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Northwind Pharmaceuticals, LLC	2020-05-27	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	REMEDYREPACK INC.	2018-03-13	2020-05-11
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Cardinal Health	2006-11-20	2021-06-30
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Med Vantx, Inc.	2011-12-13	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	AvPAK	2023-05-30	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Denton Pharma, Inc. Dba Northwind Pharmaceuticals	2019-02-13	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Remedy Repack	2012-07-18	2012-08-23
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Mylan Institutional Inc.	1995-06-12	2020-09-30
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Lake Erie Medical &Surgical Supply Dba Quality Care Products Llc	2010-12-31	2016-12-31
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Remedy Repack	2011-04-04	2012-04-04
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Carlsbad Technology, Inc.	2013-06-17	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	bryant ranch prepack	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.100 mg/1	Oral	Dispensing Solutions, Inc.	2007-03-09	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Marlex Pharmaceuticals Inc	2020-10-01	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	St. Marys Medical Park Pharmacy	2014-01-23	2016-12-31
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	REMEDYREPACK INC.	2018-02-02	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	NCS HealthCare of KY, LLC dba Vangard Labs	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Ncs Health Care Of Ky, Inc Dba Vangard Labs	1986-12-16	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Nucare Pharmaceuticals,inc.	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	REMEDYREPACK INC.	2019-03-18	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	State of Florida DOH Central Pharmacy	2009-07-01	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	NCS HealthCare of KY, Inc dba Vangard Labs	2009-09-21	2020-11-30
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Nucare Pharmaceuticals,inc.	2016-05-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Nucare Pharmaceuticals,inc.	2016-05-03	2019-12-31
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Preferred Pharmaceuticals, Inc.	2020-04-01	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	bryant ranch prepack	2020-07-01	Not applicable
Clonidine Hydrochloride	Tablet, extended release	25 mg/1	Oral	Bluepharma - Industria Farmaceutica, S.A.	2019-03-01	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Unit Dose Services	2009-09-21	2016-08-05
Clonidine Hydrochloride	Injection, solution	0.1 mg/1mL	Epidural	Zydus Pharmaceuticals USA Inc.	2018-01-31	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Med Pharma Co., Ltd.	2011-01-10	Not applicable
Clonidine hydrochloride	Tablet	0.1 mg/1	Oral	Denton Pharma, Inc. Dba Northwind Pharmaceuticals	2021-04-12	2024-10-31
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Direct Rx	2014-01-01	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Alembic Pharmaceuticals Inc.	2016-05-03	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Rebel Distributors	1987-09-04	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Denton Pharma, Inc. Dba Northwind Pharmaceuticals	2020-10-09	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Rpk Pharmaceuticals, Inc.	2016-05-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Nucare Pharmaceuticals, Inc.	1987-09-04	2019-12-31
Clonidine Hydrochloride	Tablet, extended release	0.1 mg/1	Oral	Mayne Pharma Inc.	2018-06-27	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	TYA Pharmaceuticals	1987-09-04	Not applicable
Clonidine Hydrochloride	Tablet	0.300 mg/1	Oral	Solco Healthcare Llc	2023-01-05	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Alembic Pharmaceuticals Limited	2016-05-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	State of Florida DOH Central Pharmacy	2009-07-01	Not applicable
Clonidine Hydrochloride	Injection, solution	100 ug/1mL	Intravenous	Hikma Pharmaceuticals USA Inc.	2011-01-01	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Method Pharmaceuticals, LLC	2020-07-01	Not applicable
Clonidine Hydrochloride	Tablet	0.100 mg/1	Oral	A-S Medication Solutions	2007-03-09	2015-12-31
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Nucare Pharmaceuticals,inc.	2009-09-21	Not applicable
Clonidine hydrochloride	Tablet	0.3 mg/1	Oral	Northwind Pharmaceuticals, LLC	2022-12-06	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	A-S Medication Solutions	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Clinical Solutions Wholesale, LLC	2009-09-21	2018-12-07
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	North Star Rx Llc	2013-02-04	2015-10-31
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Richmond Pharmaceuticals	1987-09-04	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Proficient Rx LP	2020-12-24	Not applicable
Clonidine Hydrochloride	Tablet	0.100 mg/1	Oral	Lake Erie Medical Dba Quality Care Produts Llc	2007-03-09	2014-12-31
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	DAVA Pharmaceuticals, Inc.	1988-04-05	2014-04-01
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	bryant ranch prepack	2016-05-03	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	A-S Medication Solutions	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Asclemed Usa, Inc.	2016-05-03	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	Actavis Pharma, Inc.	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Aphena Pharma Solutions Tennessee, Inc.	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	A-S Medication Solutions	2013-06-17	2018-07-31
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Cardinal Health	1986-12-16	2012-10-31
Clonidine hydrochloride	Tablet, extended release	0.1 mg/1	Oral	REMEDYREPACK INC.	2022-01-31	Not applicable
Clonidine Hydrochloride	Injection, solution	100 ug/1mL	Epidural	Pharma Force, Inc.	2009-10-16	Not applicable
Clonidine Hydrochloride	Tablet	0.3 mg/1	Oral	Unichem Pharmaceuticals (USA), Inc.	2009-09-21	Not applicable
Clonidine Hydrochloride	Tablet	0.2 mg/1	Oral	BluePoint Laboratories	1995-01-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	PD-Rx Pharmaceuticals, Inc.	2016-05-03	Not applicable
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Avera McKennan Hospital	2015-03-05	2017-05-24
Clonidine Hydrochloride	Tablet	0.1 mg/1	Oral	Contract Pharmacy Services Pa	2017-09-28	Not applicable
Clonidine hydrochloride extended-release	Tablet, extended release	0.1 mg/1	Oral	Prasco Laboratories	2016-06-20	Not applicable
Clonidine Hydrochloride Extended-Release	Tablet, extended release	0.1 mg/1	Oral	Par Pharmaceutical, Inc.	2013-09-30	2023-04-30
Clonidine Hydrochloride Extended-Release	Tablet, extended release	0.1 mg/1	Oral	American Health Packaging	2014-10-21	2020-06-30
Clonidine Hydrochloride Extended-Release	Tablet, extended release	0.1 mg/1	Oral	AvKARE	2018-09-13	Not applicable
Clonidine Hydrochloride Extended-Release	Tablet, extended release	0.2 mg/1	Oral	Par Pharmaceutical, Inc.	2013-09-30	2013-09-30
Clonidine Hydrochloride Extended-Release	Tablet, extended release	0.1 mg/1	Oral	Golden State Medical Supply, Inc.	2013-09-30	2023-04-30
Clonidine transdermal system	Patch	0.3 mg/1d	Transdermal	Actavis Pharma, Inc.	2014-05-06	Not applicable
Clonidine transdermal system	Patch	0.2 mg/1d	Transdermal	Actavis Pharma, Inc.	2014-05-06	Not applicable
Clonidine transdermal system	Patch	0.1 mg/1d	Transdermal	Actavis Pharma, Inc.	2014-05-06	Not applicable
Dom-clonidine	Tablet	.2 mg	Oral	Dominion Pharmacal	2003-05-22	Not applicable
Dom-clonidine	Tablet	.1 mg	Oral	Dominion Pharmacal	2003-05-22	Not applicable
Jamp Clonidine	Tablet	0.025 mg	Oral	Jamp Pharma Corporation	2023-03-07	Not applicable
Mar-clonidine	Tablet	0.025 mg	Oral	Marcan Pharmaceuticals Inc	2022-04-11	Not applicable
Mint-clonidine	Tablet	0.1 mg	Oral	Mint Pharmaceuticals Inc	2017-06-23	Not applicable
Mint-clonidine	Tablet	0.025 mg	Oral	Mint Pharmaceuticals Inc	2023-05-10	Not applicable
Mint-clonidine	Tablet	0.2 mg	Oral	Mint Pharmaceuticals Inc	2017-06-23	Not applicable
Ntp-clonidine	Tablet	0.025 mg	Oral	TEVA Canada Limited	Not applicable	Not applicable
Ntp-clonidine	Tablet	0.2 mg	Oral	TEVA Canada Limited	Not applicable	Not applicable
Ntp-clonidine	Tablet	0.1 mg	Oral	TEVA Canada Limited	Not applicable	Not applicable
Nu-clonidine Tab 0.1mg	Tablet	.1 mg	Oral	Nu Pharm Inc	1992-12-31	2012-09-04
Nu-clonidine Tab 0.2mg	Tablet	.2 mg	Oral	Nu Pharm Inc	1992-12-31	2012-09-04
Sandoz Clonidine	Tablet	0.2 mg	Oral	Sandoz Canada Incorporated	2022-02-02	Not applicable
Sandoz Clonidine	Tablet	0.1 mg	Oral	Sandoz Canada Incorporated	2022-02-02	Not applicable
Sandoz Clonidine	Tablet	0.025 mg	Oral	Sandoz Canada Incorporated	2022-02-02	Not applicable
Teva-clonidine	Tablet	0.025 mg	Oral	TEVA Canada Limited	2008-06-26	Not applicable
Teva-clonidine	Tablet	0.1 mg	Oral	TEVA Canada Limited	1993-12-31	Not applicable
Teva-clonidine	Tablet	0.2 mg	Oral	TEVA Canada Limited	1993-12-31	Not applicable

Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
Clorpres	Clonidine hydrochloride (0.2 mg/1) + Chlorthalidone (15 mg/1)	Tablet	Oral	Mylan Pharmaceuticals	1998-03-13	2018-02-28
Clorpres	Clonidine hydrochloride (0.2 mg/1) + Chlorthalidone (15 mg/1)	Tablet	Oral	Mylan Bertek Pharmaceuticals	2015-11-01	2015-11-19
Clorpres	Clonidine hydrochloride (0.1 mg/1) + Chlorthalidone (15 mg/1)	Tablet	Oral	Mylan Pharmaceuticals	1998-03-13	2018-02-28
Clorpres	Clonidine hydrochloride (0.1 mg/1) + Chlorthalidone (15 mg/1)	Tablet	Oral	Mylan Bertek Pharmaceuticals	2015-11-01	2015-11-19
Clorpres	Clonidine hydrochloride (0.2 mg/1) + Chlorthalidone (15 mg/1)	Tablet	Oral	Physicians Total Care, Inc.	2005-04-15	2011-06-30
Clorpres	Clonidine hydrochloride (0.3 mg/1) + Chlorthalidone (15 mg/1)	Tablet	Oral	Mylan Pharmaceuticals	1998-03-13	2018-02-28
Clorpres	Clonidine hydrochloride (0.3 mg/1) + Chlorthalidone (15 mg/1)	Tablet	Oral	Mylan Bertek Pharmaceuticals	2015-11-01	2015-11-19
Clorpres	Clonidine hydrochloride (0.1 mg/1) + Chlorthalidone (15 mg/1)	Tablet	Oral	Physicians Total Care, Inc.	2005-01-26	2011-06-30
Combipres 0.1/15 Tab	Clonidine hydrochloride (.1 mg) + Chlorthalidone (15 mg)	Tablet	Oral	Boehringer Ingelheim (Canada) Ltd Ltee	1974-12-31	1997-08-14
Kapvay	Clonidine hydrochloride (0.1 mg/1) + Clonidine hydrochloride (0.2 mg/1)	Kit	Oral	Shionogi	2010-12-09	2014-08-31
Kapvay	Clonidine hydrochloride (0.1 mg/1) + Clonidine hydrochloride (0.2 mg/1)	Kit	Oral	Shionogi	2010-12-09	2014-08-31