Dr. Roy L. Freeman, MD | Boston, MA | Neurologist | US News Doctors

Overview

Dr. Roy L. Freeman is a neurologist in Boston, Massachusetts and is affiliated with Beth Israel Deaconess Medical Center. He received his medical degree from University of Cape Town Faculty of Medicine and has been in practice for more than 20 years. Dr. Roy L. Freeman accepts Medicare, Blue Cross, United Healthcare - see other insurance plans accepted.

Doctor's Details

Specialties

Specialty

Neurology

Neurologists diagnose and treat brain and nervous system disorders. Examples of medical conditions they treat include migraines, strokes, epilepsy, multiple sclerosis and sleep disorders, such as narcolepsy.

Subspecialties

Neurophysiology

Doctor's Details

Patient Experience

Patient Awards

Provides clear explanation

Practices at Best Hospital

Provides clear explanation

Provides clear information and answers questions in a way patients understand.

Practices at Best Hospital

This doctor practices at a U.S. News Best Regional Hospital

Overall Patient Experience

Very Positive

(4/5)

16 Reviews Total|0 Reviews Within Last 12 Months

Thoroughness of Examination

Previous patients' satisfaction in their perception of the thoroughness of the examination they received from this physician

Positive

(3/5)

Ability to Answer Questions

Previous patients' assessment of this physician's ability to answer all of their questions

Excellent

(5/5)

Provider's follow-up

Previous patients' satisfaction of the followup care they received from this physician and responsiveness to their concerns

Fair

(2/5)

Amount of Time with Patient

Previous patients' satisfaction with the time this physician spent with them during appointments

Fair

(2/5)

Provider's Attitude

Previous patients' assessment of this physician's friendliness and caring attitude

Fair

(2/5)

Perceived Outcomes

Previous patients' satisfaction with the physician's treatment of a condition or outcome of a procedure

Fair

(2/5)

General Feedback

Previous patients' general assessment of this physician

Excellent

(5/5)

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Areas of Expertise for Dr. Freeman

This doctor provides the following types of care. The more often a doctor has treated a particular condition or has performed a particular surgery, the more expertise they may have in treating patients with similar needs. Based on three years (2020-2022) of Medicare data, each scale below indicates the volume of episodes compared to other doctors who treat the same condition. Click here to learn more about our methodology.

Disorders of the thoracic spineDisorders of the thoracic spine (spine stenosis, spondylosis, or spondylolisthesis) can cause discomfort and issues with the mid-back area.

Least

State Average
This Doctor

Most

Seizures and epilepsySeizures are sudden, abnormal bursts of electrical activity in the brain. Epilepsy is a condition characterized by recurrent seizures.

Least

State Average
This Doctor

Most

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Accepts Medicare

Accepts Medicaid

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Location & Contact Information

Doctor Address

1 Deaconess Rd, Beth Israel Deaconess Med Ctr Palmer 111, Boston, MA, 02215

(617) 632-8454

Affiliated Hospitals

1

Beth Israel Deaconess Medical Center

Where does Dr. Freeman practice?

Doctor’s Office

Harvard Medical Faculty Phys At Beth Israel Deaconess Med Ctr, Inc

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Hospital Affiliations

Beth Israel Deaconess Medical CenterBoston, MA

#3 in Massachusetts

High Performing in Neurology & Neurosurgery and Stroke

Education & Experience

Medical School & Residency

Brigham and Women's Hospital

Internship, Internal Medicine, 1978-1979

University of Cape Town Faculty of Medicine

Medical School

Beth Israel Deaconess Medical Center/Harvard Medical School

Residency, Neurology, 1979-1982

Certifications & Licensure

American Board of Psychiatry and Neurology

Certified in Neurology

MA State Medical License

Active through 2025

Publications

State-of-the-Art Review

Roy Freeman, Mitchell G Miglis, Christopher Gibbons, Pearl Jones

Patient engagement in designing, conducting, and disseminating clinical pain research: IMMPACT recommended considerations.

Simon Haroutounian, Katherine J Holzer, Robert D Kerns, Christin Veasley, Robert H Dworkin, Dennis C Turk, Kristin L Carman, Christine T Chambers, Penney Cowan, Robert R Edwards, James C Eisenach, John T Farrar, McKenzie Ferguson, Laura P Forsythe, Roy Freeman, Jennifer S Gewandter, Ian Gilron, Christine Goertz, Hanna Grol-Prokopczyk, Smriti Iyengar, Isabel Jordan, Cornelia Kamp, Bethea A Kleykamp, Rachel L Knowles, Dale J Langford, Sean Mackey, Richard Malamut, John Markman, Kathryn R Martin, Ewan McNicol, Kushang V Patel, Andrew S C Rice, Michael Rowbotham, Friedhelm Sandbrink, Lee S Simon, Deborah J Steiner, Jan Vollert

Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients With Synucleinopathies.

Christopher H Gibbons, Todd Levine, Charles Adler, Bailey Bellaire, Ningshan Wang, Jade Stohl, Pinky Agarwal, Georgina M Aldridge, Alexandru Barboi, Virgilio G H Evidente, Douglas Galasko, Michael D Geschwind, Alejandra Gonzalez-Duarte, Ramon Gil, Mark Gudesblatt, Stuart H Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J Liu, Nikolaus R McFarland, Mitchell Miglis, Adam Reynolds, Gregory A Sahagian, Marie-Helene Saint-Hillaire, Julie B Schwartzbard, Wolfgang Singer, Michael J Soileau, Steven Vernino, Oleg Yerstein, Roy Freeman

Plasma proteomic analysis on neuropathic pain in idiopathic peripheral neuropathy patients.

Perry T C van Doormaal, Simone Thomas, Senda Ajroud-Driss, Robert N Cole, Lauren R DeVine, Mazen M Dimachkie, Stefanie Geisler, Roy Freeman, David M Simpson, J Robinson Singleton, A Gordon Smith, Amro Stino, , Ahmet Höke

Clinical Trial-Ready Patient Cohorts for Multiple System Atrophy: Coupling Biospecimen and iPSC Banking to Longitudinal Deep-Phenotyping.

Alain Ndayisaba, Ariana T Pitaro, Andrew S Willett, Kristie A Jones, Claudio Melo de Gusmao, Abby L Olsen, Jisoo Kim, Eero Rissanen, Jared K Woods, Sharan R Srinivasan, Anna Nagy, Amanda Nagy, Merlyne Mesidor, Steven Cicero, Viharkumar Patel, Derek H Oakley, Idil Tuncali, Katherine Taglieri-Noble, Emily C Clark, Jordan Paulson, Richard C Krolewski, Gary P Ho, Albert Y Hung, Anne-Marie Wills, Michael T Hayes, Jason P Macmore, Luigi Warren, Pamela G Bower, Carol B Langer, Lawrence R Kellerman, Christopher W Humphreys, Bonnie I Glanz, Elodi J Dielubanza, Matthew P Frosch, Roy L Freeman, Christopher H Gibbons, Nadia Stefanova, Tanuja Chitnis, Howard L Weiner, Clemens R Scherzer, Sonja W Scholz, Dana Vuzman, Laura M Cox, Gregor Wenning, Jeremy D Schmahmann, Anoopum S Gupta, Peter Novak, Geoffrey S Young, Mel B Feany, Tarun Singhal, Vikram Khurana

Correction to: Clinical trial-ready patient cohorts for multiple system atrophy: coupling biospecimen and iPSC banking to longitudinal deep-phenotyping.

Alain Ndayisaba, Ariana T Pitaro, Andrew S Willett, Kristie A Jones, Claudio Melo de Gusmao, Abby L Olsen, Jisoo Kim, Eero Rissanen, Jared K Woods, Sharan R Srinivasan, Anna Nagy, Amanda Nagy, Merlyne Mesidor, Steven Cicero, Viharkumar Patel, Derek H Oakley, Idil Tuncali, Katherine Taglieri-Noble, Emily C Clark, Jordan Paulson, Richard C Krolewski, Gary P Ho, Albert Y Hung, Anne-Marie Wills, Michael T Hayes, Jason P Macmore, Luigi Warren, Pamela G Bower, Carol B Langer, Lawrence R Kellerman, Christopher W Humphreys, Bonnie I Glanz, Elodi J Dielubanza, Matthew P Frosch, Roy L Freeman, Christopher H Gibbons, Nadia Stefanova, Tanuja Chitnis, Howard L Weiner, Clemens R Scherzer, Sonja W Scholz, Dana Vuzman, Laura M Cox, Gregor Wenning, Jeremy D Schmahmann, Anoopum S Gupta, Peter Novak, Geoffrey S Young, Mel B Feany, Tarun Singhal, Vikram Khurana

Effect of hypoglycemia on baroreflex sensitivity in individuals with type 2 diabetes: implications for autonomic control of cardiovascular function in diabetes.

Andrea V Haas, Andrew Koefoed, Rebecca M Easly, Johanna Celli, Mahyar Heydarpour, Istvan Bonyhay, Roy Freeman, Gail K Adler

Research objectives and general considerations for pragmatic clinical trials of pain treatments: IMMPACT statement.

David J Hohenschurz-Schmidt, Dan Cherkin, Andrew S C Rice, Robert H Dworkin, Dennis C Turk, Michael P McDermott, Matthew J Bair, Lynn L DeBar, Robert R Edwards, John T Farrar, Robert D Kerns, John D Markman, Michael C Rowbotham, Karen J Sherman, Ajay D Wasan, Penney Cowan, Paul Desjardins, McKenzie Ferguson, Roy Freeman, Jennifer S Gewandter, Ian Gilron, Hanna Grol-Prokopczyk, Sharon H Hertz, Smriti Iyengar, Cornelia Kamp, Barbara I Karp, Bethea A Kleykamp, John D Loeser, Sean Mackey, Richard Malamut, Ewan McNicol, Kushang V Patel, Friedhelm Sandbrink, Kenneth Schmader, Lee Simon, Deborah J Steiner, Christin Veasley, Jan Vollert

Cannabinoid Therapy: Attitudes and Experiences of People With Chronic Pain.

Jennifer S Gewandter, Robert R Edwards, Kevin P Hill, Ajay D Wasan, Julia E Hooker, Emma C Lape, Soroush Besharat, Penney Cowan, Bernard Le Foll, Joseph W Ditre, Roy Freeman

Efficacy and safety of vixotrigine in idiopathic or diabetes-associated painful small fibre neuropathy (CONVEY): a phase 2 placebo-controlled enriched-enrolment randomised withdrawal study.

Catharina G Faber, Nadine Attal, Giuseppe Lauria, Robert H Dworkin, Roy Freeman, Katherine T Dawson, Helen Finnigan, Amirhossein Hajihosseini, Himanshu Naik, Michael Serenko, Christopher J Morris, Mona Kotecha

Two-Year observational study of autonomic skin function in patients with Parkinson's disease compared to healthy individuals.

Timo Siepmann, Martin Arndt, Annahita Sedghi, Szabolcs Szatmári Jr, Tamás Horváth, Annamária Takáts, Dániel Bereczki, Mats Leif Moskopp, Sylvia Buchmann, Cornelia Skowronek, Wagner Zago, Warunya Woranush, Razvan Lapusca, Marie Luise Weidemann, Christopher H Gibbons, Roy Freeman, Heinz Reichmann, Volker Puetz, Kristian Barlinn, Alexandra Pintér, Ben Min-Woo Illigens

Cutaneous α-Synuclein Signatures in Patients With Multiple System Atrophy and Parkinson Disease.

Christopher Gibbons, Ningshan Wang, Sharika Rajan, Drew Kern, Jose-Alberto Palma, Horacio Kaufmann, Roy Freeman

Cutaneous amyloid is a biomarker in early ATTRv neuropathy and progresses across disease stages.

Roy Freeman, Alejandra Gonzalez-Duarte, Fabio Barroso, Marta Campagnolo, Sharika Rajan, Jennifer Garcia, Jee Young Kim, Ningshan Wang, Lucas Orellana, Christopher Gibbons

The solitary nucleus connectivity to key autonomic regions in humans.

Julia Forstenpointner, Anne Margarette S Maallo, Igor Elman, Scott Holmes, Roy Freeman, Ralf Baron, David Borsook

Stress, hypoglycemia, and the autonomic nervous system.

Andrea Haas, David Borsook, Gail Adler, Roy Freeman

The Movement Disorder Society Criteria for the Diagnosis of Multiple System Atrophy.

Gregor K Wenning, Iva Stankovic, Luca Vignatelli, Alessandra Fanciulli, Giovanna Calandra-Buonaura, Klaus Seppi, Jose-Alberto Palma, Wassilios G Meissner, Florian Krismer, Daniela Berg, Pietro Cortelli, Roy Freeman, Glenda Halliday, Günter Höglinger, Anthony Lang, Helen Ling, Irene Litvan, Phillip Low, Yasuo Miki, Jalesh Panicker, Maria Teresa Pellecchia, Niall Quinn, Ryuji Sakakibara, Maria Stamelou, Eduardo Tolosa, Shoji Tsuji, Tom Warner, Werner Poewe, Horacio Kaufmann

Synuclein-One study: skin biopsy detection of phosphorylated α-synuclein for diagnosis of synucleinopathies.

Christopher H Gibbons, Roy Freeman, Bailey Bellaire, Charles H Adler, Dan Moore, Todd Levine

The omnipresence of autonomic modulation in health and disease.

Julia Forstenpointner, Igor Elman, Roy Freeman, David Borsook

The threshold tracking nerve conduction study technique: Experience of clinical users unfamiliar with a research-grade neuronal excitability system.

C E McIlduff, B J Wainger, R L Freeman, S Samaan, I Yator, H Gutierrez, S Verga, S B Rutkove

Research approaches for evaluating opioid sparing in clinical trials of acute and chronic pain treatments: Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials recommendations.

Jennifer S. Gewandter, Shannon M. Smith, Robert H. Dworkin, Dennis C. Turk, Tong J. Gan, Ian Gilron, Sharon Hertz, Nathaniel P. Katz, John D. Markman, Srinivasa N. Raja, Michael C. Rowbotham, Brett R. Stacey, Eric C. Strain, Denham S. Ward, John T. Farrar, Kurt Kroenke, James P. Rathmell, Richard Rauck, Colville Brown, Penney Cowan, Robert R. Edwards, James C. Eisenach, McKenzie C Ferguson, Roy Freeman, Royston A. Gray, Kathryn Giblin, Hanna Grol-Prokopczyk, Jennifer A. Haythornthwaite, Robert N. Jamison, Marc O. Martel, Ewan McNicol, Michael L. Oshinsky, Friedhelm Sandbrink, Joachim Scholz, Richard Scranton, Lee S. Simon, Deborah Steiner, Kenneth M. Verburg, Ajay D. Wasan, Kerry Wentworth

Effect of adrenocorticotropic hormone infusion on circulating sclerostin levels.

Sarah Zaheer, Kayla M. Meyer, Rebecca M. Easly, Omar Bayomy, Janet H Leung, Andrew W. Koefoed, Mahyar Heydarpour, Roy Freeman, Gail K. Adler

Diagnostic criteria for initial orthostatic hypotension: a narrative review.

Daan J.L. van Twist, Mark P. M. Harms, Veera K. van Wijnen, Victoria E. Claydon, Roy Freeman, William P. Cheshire, Wouter Wieling

X-Linked Dystonia-Parkinsonism (“Lubag”) May Present with Peripheral Synucleinopathy

Virgilio Gerald H. Evidente, Danica H. Evidente, Susan C. Ortega, Todd Levine, Roy Freeman, ChristopherH. Gibbons

Screening, diagnosis and management of diabetic sensorimotor polyneuropathy in clinical practice: International expert consensus recommendations.

Dan Ziegler, Solomon Tesfaye, Vincenza Spallone, Irina Gurieva, Juma Al Kaabi, Boris Mankovsky, Emil Martinka, Gabriela Radulian, Khue Thy Nguyen, Alin Stirban, Tsvetalina Tankova, Tamás Várkonyi, Roy Freeman, Péter Kempler, Andrew J.M. Boulton

Benefit-risk assessment and reporting in clinical trials of chronic pain treatments: IMMPACT recommendations.

Bethea A. Kleykamp, Robert H. Dworkin, Dennis C. Turk, Zubin Bhagwagar, Penney Cowan, Christopher Eccleston, Susan S. Ellenberg, Scott R. Evans, John T. Farrar, Roy Freeman, Louis P. Garrison, Jennifer S. Gewandter, Veeraindar Goli, Smriti Iyengar, Alejandro R. Jadad, Mark P. Jensen, Roderick Junor, Nathaniel P. Katz, J Patrick Kesslak, Ernest A. Kopecky, Dmitri Lissin, John D. Markman, Michael P. McDermott, Philip J. Mease, Alec B. O'Connor, Kushang V. Patel, Srinivasa N. Raja, Michael C. Rowbotham, Cristina Sampaio, Jasvinder A. Singh, Ilona Steigerwald, Vibeke Strand, Leslie Tive, Jeffrey Tobias, Ajay D. Wasan, Hilary D. Wilson

Randomized, double-blind, placebo-controlled trial of ISC 17536, an oral inhibitor of transient receptor potential ankyrin 1, in patients with painful diabetic peripheral neuropathy: impact of preserved small nerve fiber function.

Sunil M. Jain, Ramanathan Balamurugan, Monika Tandon, Neelufar Mozaffarian, Girish Gudi, Yacine Salhi, Robert Holland, Roy Freeman, Ralf Baron

Pure autonomic failure and the differential diagnosis of autonomic peripheral neuropathies.

Alejandra González-Duarte, Aditi Varma-Doyle, Roy Freeman

Cardiovascular exercise as a treatment of postural orthostatic tachycardia syndrome: A pragmatic treatment trial.

Christopher H. Gibbons, Gustavo Silva, Roy Freeman

Cutaneous Alpha-Synuclein is Correlated with Autonomic Impairment in Isolated REM Sleep Behavior Disorder.

Mitchell G. Miglis, Jennifer Zitser, Logan Schneider, Emmanuel H. During, Safwan Jaradeh, Roy Freeman, Christopher H. Gibbons

Validation of the Korean version of the Boston Autonomic Symptom Questionnaire.

Eun Hee Sohn, Christopher H. Gibbons, Roy Freeman, Ae Young Lee, Mi Sook Jung, Soo Young Kim

Postural orthostatic tachycardia syndrome (POTS): Priorities for POTS care and research from a 2019 National Institutes of Health Expert Consensus Meeting - Part 2.

Satish R. Raj, Kate M. Bourne, Lauren E. Stiles, Mitchell G. Miglis, Melissa M. Cortez, Amanda J. Miller, Roy Freeman, Italo Biaggioni, Peter C. Rowe, Robert S. Sheldon, Cyndya A. Shibao, André Diedrich, David M. Systrom, Glen A. Cook, Taylor A. Doherty, Hasan I. Abdallah, Blair P. Grubb, Artur Fedorowski, Julian M. Stewart, Amy C. Arnold, Laura A. Pace, Jonas Axelsson, Jeffrey R. Boris, Jeffrey P. Moak, Brent P. Goodman, Kamal R. Chémali, Tae H. Chung, David S. Goldstein, Anil Darbari, Steven Vernino

Postural orthostatic tachycardia syndrome (POTS): State of the science and clinical care from a 2019 National Institutes of Health Expert Consensus Meeting - Part 1.

Steven Vernino, Kate M. Bourne, Lauren E. Stiles, Blair P. Grubb, Artur Fedorowski, Julian M. Stewart, Amy C. Arnold, Laura A. Pace, Jonas Axelsson, Jeffrey R. Boris, Jeffrey P. Moak, Brent P. Goodman, Kamal R. Chémali, Tae H. Chung, David S. Goldstein, André Diedrich, Mitchell G. Miglis, Melissa M. Cortez, Amanda J. Miller, Roy Freeman, Italo Biaggioni, Peter C. Rowe, Robert S. Sheldon, Cyndya A. Shibao, David M. Systrom, Glen A. Cook, Taylor A. Doherty, Hasan I. Abdallah, Anil Darbari, Satish R. Raj

Reader Response: In Vivo Distribution of α-Synuclein in Multiple Tissues and Biofluids in Parkinson Disease.

Christopher H. Gibbons, Vincenzo Donadio, Claudia Sommer, Rocco Liguori, Giuseppe Lauria Pinter, Raffaella Lombardi, Kathrin Doppler, Roy Freeman

Myeloid Mineralocorticoid Receptor Transcriptionally Regulates P-Selectin Glycoprotein Ligand-1 and Promotes Monocyte Trafficking and Atherosclerosis.

Joshua J. Man, Qing Lu, M. Elizabeth Moss, Brigett Carvajal, Wendy Baur, Amanda E Garza, Roy Freeman, Marina Anastasiou, Njabulo Ngwenyama, Gail K. Adler, Pilar Alcaide, Iris Z. Jaffe

Cutaneous alpha-synuclein deposition in postural tachycardia patients.

Todd Levine, Bailey Bellaire, Christopher H. Gibbons, Roy Freeman

Recommendations for tilt table testing and other provocative cardiovascular autonomic tests in conditions that may cause transient loss of consciousness : Consensus statement of the European Federation of Autonomic Societies (EFAS) endorsed by the American Autonomic Society (AAS) and the European Academy of Neurology (EAN).

Roland D. Thijs, Michele Brignole, Cristian Falup-Pecurariu, Alessandra Fanciulli, Roy Freeman, Pietro Guaraldi, Jens Jordan, Mario Habek, Max J. Hilz, Anne Pavy-Le Traon, Iva Stankovic, Walter Struhal, Richard Sutton, Gregor K. Wenning, J. Gert van Dijk

Recommendations for tilt table testing and other provocative cardiovascular autonomic tests in conditions that may cause transient loss of consciousness : Consensus statement of the European Federation of Autonomic Societies (EFAS) endorsed by the American Autonomic Society (AAS) and the European Academy of Neurology (EAN).

Roland D. Thijs, Michele Brignole, Cristian Falup-Pecurariu, Alessandra Fanciulli, Roy Freeman, Pietro Guaraldi, Jens Jordan, Mario Habek, Max J. Hilz, Anne Pavy-LeTraon, Iva Stankovic, Walter Struhal, Richard Sutton, Gregor K. Wenning, J. Gert van Dijk

AAAPT Diagnostic Criteria for Acute Neuropathic Pain.

Tina L. Doshi, Robert H. Dworkin, Rosemary C. Polomano, Daniel B. Carr, Robert R. Edwards, Nanna B. Finnerup, Roy Freeman, Judith A. Paice, Steven J. Weisman, Srinivasa N. Raja

Corrigendum to "Electrodiagnostic assessment of the autonomic nervous system: A consensus statement endorsed by the American Autonomic Society, American Academy of Neurology, and the International Federation of Clinical Neurophysiology" [Clin. Neurophysiol. 132(2) (2021) 666-682].

William P. Cheshire, Roy Freeman, Christopher H. Gibbons, Pietro Cortelli, Gregor K. Wenning, Max J. Hilz, Judith M. Spies, Axel Lipp, Paola Sandroni, Naoki Wada, Tadaaki Mano, Hyun Ah Kim, Kurt Kimpinski, Valeria Iodice, Juan Idiáquez, Pariwat Thaisetthawatkul, Elizabeth A. Coon, Phillip A. Low, Wolfgang Singer

Efficacy and safety of EMA401 in peripheral neuropathic pain: results of 2 randomised, double-blind, phase 2 studies in patients with postherpetic neuralgia and painful diabetic neuropathy.

Andrew S.C. Rice, Robert H. Dworkin, Nanna B. Finnerup, Nadine Attal, Praveen Anand, Roy Freeman, Alessandro Piaia, Francesca Callegari, Christie Doerr, Subhayan Mondal, Nisha Narayanan, Laurent Ecochard, Yanina Flossbach, Shaloo Pandhi

Diagnostic criteria for idiopathic small fiber neuropathy: A systematic review.

Simon Haroutounian, Marko S. Todorovic, Mathias Leinders, Marta Campagnolo, Jennifer S. Gewandter, Robert H. Dworkin, Roy Freeman

Electrodiagnostic assessment of the autonomic nervous system: A consensus statement endorsed by the American Autonomic Society, American Academy of Neurology, and the International Federation of Clinical Neurophysiology.

William P. Cheshire, Roy Freeman, Christopher H. Gibbons, Pietro Cortelli, Gregor K. Wenning, Max J. Hilz, Judith M. Spies, Axel Lipp, Paola Sandroni, Naoki Wada, Akiko Mano, Hyun Ah Kim, Kurt Kimpinski, Valeria Iodice, Juan Idiáquez, Pariwat Thaisetthawatkul, Elizabeth A. Coon, Phillip A. Low, Wolfgang Singer

Idiopathic distal sensory polyneuropathy: ACTTION diagnostic criteria.

Roy Freeman, Jennifer S. Gewandter, Catharina G. Faber, Christopher H. Gibbons, Simon Haroutounian, Giuseppe Lauria, Todd Levine, Rayaz A. Malik, J. Robinson Singleton, A. Gordon Smith, Josh Bell, Robert H. Dworkin, Eva L. Feldman, David N. Herrmann, Ahmet Hoke, Noah Kolb, Heikki Mansikka, Anne Louise Oaklander, Amanda C. Peltier, Michael Polydefkis, Elissa Ritt, James W. Russell, Stephen Sainati, Deborah Steiner, Roi Treister, Nurcan Üçeyler

Interpretation of chronic pain clinical trial outcomes: IMMPACT recommended considerations.

Shannon M. Smith, Robert H. Dworkin, Dennis C. Turk, Michael P. McDermott, Christopher Eccleston, John T. Farrar, Michael C. Rowbotham, Zubin Bhangwagar, Laurie B. Burke, Penney Cowan, Susan S. Ellenberg, Scott R. Evans, Roy Freeman, Louis P. Garrison, Smriti Iyengar, Alejandro R. Jadad, Mark P. Jensen, Roderick Junor, Cornelia Kamp, Nathaniel P. Katz, J Patrick Kesslak, Ernest A. Kopecky, Dmitri Lissin, John D. Markman, Philip J. Mease, Alec B. O'Connor, Kushang V. Patel, Srinivasa N. Raja, Cristina Sampaio, David A. Schoenfeld, Jasvinder A. Singh, Ilona Steigerwald, Vibeke Strand, Leslie Tive, Jeffrey Tobias, Ajay D. Wasan, Hilary Wilson

Reliability and Validity of the Boston Bedside Quantitative Sensory Testing Battery for Neuropathic Pain.

Alexandra Koulouris, Robert R. Edwards, K. Dorado, Kristin L. Schreiber, Asimina Lazaridou, Sharika Rajan, Jeffrey White, Jenniffer Garcia, Christopher H. Gibbons, Roy Freeman

Phosphorylated Alpha-Synuclein Within Cutaneous Autonomic Nerves of Patients With Parkinson's Disease: The Implications of Sample Thickness on Results.

Ningshan Wang, Jennifer Garcia, Roy Freeman, Christopher H. Gibbons

Delayed orthostatic hypotension.

Christopher H. Gibbons, Roy Freeman

Improving Study Conduct and Data Quality in Clinical Trials of Chronic Pain Treatments: IMMPACT Recommendations

Jennifer S. Gewandter, Robert H. Dworkin, Dennis C. Turk, Eric Devine, David J. Hewitt, Mark P. Jensen, Nathaniel P. Katz, Amy A. Kirkwood, Richard Malamut, John D. Markman, Bernard Vrijens, Laurie B. Burke, James N. Campbell, Daniel B. Carr, Philip G. Conaghan, Penney Cowan, Mittie K. Doyle, Robert R. Edwards, Scott R. Evans, John T. Farrar, Roy Freeman, Ian Gilron, Dean Juge, Robert D. Kerns, Ernest A. Kopecky, Michael P. McDermott, G. Niebler, Kushang V. Patel, Richard Rauck, Andrew S.C. Rice, Michael C. Rowbotham, Nelson E. Sessler, Lee S. Simon, Neil Singla, Vladimir Skljarevski, Tina Tockarshewsky, Geertrui F. Vanhove, Ajay D. Wasan, James Witter

ACTH Infusion Impairs Baroreflex Sensitivity-Implications for Cardiovascular Hypoglycemia-Associated Autonomic Failure.

Janet H Leung, Omar Bayomy, Istvan Bonyhay, Johanna Celli, Jeffrey White, Roy Freeman, Gail K. Adler

A novel method to quantify cutaneous vascular innervation.

Eun-Hee Sohn, Bum Chun Suh, Ningshan Wang, Roy Freeman, Christopher H. Gibbons

Response to: Human papillomavirus (HPV) vaccine safety concerning POTS, CRPS and related conditions

Alexandru Barboi, Christopher H. Gibbons, Eduardo E Bennaroch, Italo Biaggioni, Mark W. Chapleau, Gisela Chelimsky, Thomas C. Chelimsky, William P. Cheshire, Victoria E Claydon, Roy Freeman, David S. Goldstein, Michael J. Joyner, Horacio Kaufmann, Phillip A. Low, Lucy Norcliffe-Kaufmann, David Robertson, Cyndya A Shibao, Wolfgang Singer, Howard Snapper, Steven Vernino, Satish R. Raj

Symptom Recognition Is Impaired in Patients With Orthostatic Hypotension.

Roy Freeman, Ben Min-Woo Illigens, Razvan Lapusca, Marta Campagnolo, Ahmad R. Abuzinadah, Istvan Bonyhay, Dong In Sinn, Mitchell G. Miglis, Jeffrey White, Christopher H. Gibbons

Human papillomavirus (HPV) vaccine and autonomic disorders: a position statement from the American Autonomic Society.

Alexandru Barboi, Christopher H. Gibbons, Felicia B. Axelrod, Eduardo E. Benarroch, Italo Biaggioni, Mark W. Chapleau, Gisela Chelimsky, Thomas C. Chelimsky, William P. Cheshire, Victoria E. Claydon, Roy Freeman, David S. Goldstein, Michael J. Joyner, Horacio Kaufmann, Phillip A. Low, Lucy Norcliffe-Kaufmann, David Robertson, Cyndya A. Shibao, Wolfgang Singer, Howard Snapper, Steven Vernino, Satish R. Raj

Autonomic Peripheral Neuropathy.

Roy Freeman

Skin Biopsy in Evaluation of Autonomic Disorders.

Christopher H. Gibbons, Ningshan Wang, Jee Young Kim, Marta Campagnolo, Roy Freeman

Human papillomavirus (HPV) vaccine and autonomic disorders: a position statement from the American Autonomic Society

Alexandru Barboi, Christopher H. Gibbons, Felicia B. Axelrod, Eduardo E. Benarroch, Italo Biaggioni, Mark W. Chapleau, Gisela Chelimsky, Thomas C. Chelimsky, William P. Cheshire, Victoria E. Claydon, Roy Freeman, David S. Goldstein, Michael J. Joyner, Horacio Kaufmann, Phillip A. Low, Lucy Norcliffe-Kaufmann, David Robertson, Cyndya A. Shibao, Wolfgang Singer, Howard Snapper, Steven Vernino, Satish R. Raj

Association of innervation-adjusted alpha-synuclein in arrector pili muscles with cardiac noradrenergic deficiency in autonomic synucleinopathies.

Risa Isonaka, Christopher H. Gibbons, Ningshan Wang, Roy Freeman, David S. Goldstein

Clinician-rated measures for distal symmetrical axonal polyneuropathy: ACTTION systematic review

Jennifer S. Gewandter, Christopher H. Gibbons, Marta Campagnolo, Joonho Lee, Jenna Chaudari, Nam Ward, Laurie B. Burke, Guido Cavaletti, David N. Herrmann, Justin C. McArthur, James W. Russell, A. Gordon Smith, Shannon M. Smith, Dennis C. Turk, Robert H. Dworkin, Roy Freeman

Small fibre neuropathy assessments in early stages of hATTR amyloidosis.

Alejandra González-Duarte, Karla Cárdenas-Soto, Omar Fueyo, Carlo-Enrico Bañuelos, Christopher H. Gibbons, Roy Freeman

A critique of the second consensus criteria for multiple system atrophy

Iva Stankovic, Niall Quinn, Luca Vignatelli, Angelo Antonini, Daniela Berg, Elizabeth A. Coon, Pietro Cortelli, Alessandra Fanciulli, Joaquim J. Ferreira, Roy Freeman, Glenda M. Halliday, Günter U. Höglinger, Valeria Iodice, Horacio Kaufmann, Thomas Klockgether, Vladimir S. Kostic, Florian Krismer, Anthony E. Lang, Johannes Levin, Phillip A. Low, Christopher J. Mathias, Wassillios G. Meissner, Lucy Norcliffe Kaufmann, Jose-Alberto Palma, Jalesh N. Panicker, Maria Teresa Pellecchia, Ryuji Sakakibara, Jeremy D. Schmahmann, Sonja W. Scholz, Wolfgang Singer, Maria Stamelou, Eduardo Tolosa, Shoji Tsuji, Klaus Seppi, Werner Poewe, Gregor K. Wenning

A practical guide to active stand testing and analysis using continuous beat-to-beat non-invasive blood pressure monitoring

Ciaran Finucane, Veera K. van Wijnen, Chie Wei Fan, Christopher Soraghan, L Byrne, Berend E. Westerhof, Roy Freeman, Artur Fedorowski, Mark P. M. Harms, Wouter Wieling, Rose Anne Kenny

AAPT Diagnostic Criteria for Peripheral Neuropathic Pain: Focal and Segmental Disorders.

Roy Freeman, Robert R. Edwards, Ralf Baron, Stephen Bruehl, Giorgio Cruccu, Robert H. Dworkin, Simon Haroutounian

Peripheral Neuropathy Research Registry: A prospective cohort.

Simone Thomas, Senda Ajroud-Driss, Mazen M. Dimachkie, Christopher H. Gibbons, Roy Freeman, David M. Simpson, J. Robinson Singleton, A. Gordon Smith, Ahmet Hoke

Structural, functional, and symptom relations in painful distal symmetric polyneuropathies: a systematic review.

Páll Karlsson, Alexander Hincker, Troels S. Jensen, Roy Freeman, Simon Haroutounian

Orthostatic Hypotension: JACC State-of-the-Art Review

Roy Freeman, Ahmad R. Abuzinadah, Christopher H. Gibbons, Pearl K. Jones, Mitchell G. Miglis, Dong In Sinn

Trial designs for chemotherapy-induced peripheral neuropathy prevention: ACTTION recommendations

Jennifer S. Gewandter, Joanna M. Brell, Guido Cavaletti, Patrick M. Dougherty, Scott R. Evans, Lynn J. Howie, Michael P. McDermott, Ann M. O'Mara, A. Gordon Smith, Daniela Dastros-Pitei, Lynn R. Gauthier, Simon Haroutounian, Matthew Jarpe, Nathaniel P. Katz, Charles L. Loprinzi, Paul G. Richardson, Ellen M. Lavoie-Smith, Patrick Y. Wen, Dennis C. Turk, Robert H. Dworkin, Roy Freeman

Orthostatic heart rate changes in patients with autonomic failure caused by neurodegenerative synucleinopathies

Lucy Norcliffe-Kaufmann, Horacio Kaufmann, Jose-Alberto Palma, Cyndya A. Shibao, Italo Biaggioni, Amanda C. Peltier, Wolfgang Singer, Phillip A. Low, David S. Goldstein, Christopher H. Gibbons, Roy Freeman, David Robertson

Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting

Ryan R. Walsh, Florian Krismer, Wendy R Galpern, Gregor K. Wenning, Phillip A. Low, Glenda M. Halliday, Walter J. Koroshetz, Janice L. Holton, Niall Quinn, Olivier Rascol, Leslie M. Shaw, David Eidelberg, Pam Bower, Jeffrey L. Cummings, Victor Abler, Judy Biedenharn, Gal Bitan, David J. Brooks, Patrik Brundin, Hubert H. Fernandez, Philip Fortier, Roy Freeman, Thomas Gasser, Art Hewitt, Günter U. Höglinger, Matthew J. Huentelman, Poul Henning Jensen, Andreas Jeromin, Un Jung Kang, Horacio Kaufmann, Lawrence Kellerman, Vikram Khurana, Thomas Klockgether, Woojin S. Kim, Carol Langer, Peter A. LeWitt, Eliezer Masliah, Wassilios G. Meissner, Ronald Melki, Susanne Ostrowitzki, Steven Piantadosi, Werner Poewe, David Robertson, Cyndi Roemer, Dale Schenk, Michael G. Schlossmacher, Jeremy D. Schmahmann, Klaus Seppi, Lily Shih, A. Siderowf, Glenn T. Stebbins, Nadia Stefanova, Shoji Tsuji, Sharon Sutton, Jing Zhang

Na-V channel variants in patients with painful and nonpainful peripheral neuropathy

Samir Wadhawan, Saumya Pant, Ryan Golhar, Stefan Kirov, John Thompson, Leslie Jacobsen, Irfan Qureshi, Senda Ajroud-Driss, Roy Freeman, David M. Simpson, A. Gordon Smith, Ahmet Hoke, Linda J. Bristow

Noninvasive beat-to-beat finger arterial pressure monitoring during orthostasis: a comprehensive review of normal and abnormal responses at different ages.

Veera K. van Wijnen, Ciaran Finucane, Mark P. M. Harms, Hugh Nolan, R.L. Freeman, Berend E. Westerhof, Rose Anne Kenny, J C Ter Maaten, Wouter Wieling

Author response: Effects of orthostatic hypotension on cognition in Parkinson disease.

Justin Centi, Roy Freeman, Christopher H. Gibbons, Sandy Neargarder, Alexander O. Canova, Alice Cronin-Golomb

The diagnostic challenge of small fibre neuropathy: clinical presentations, evaluations, and causes

Astrid Juhl Terkelsen, Páll Karlsson, Giuseppe Lauria, Roy Freeman, Nanna B. Finnerup, Troels S. Jensen

Chemotherapy-induced peripheral neuropathy clinical trials: Review and recommendations

Jennifer S. Gewandter, Roy Freeman, Rachel A. Kitt, Guido Cavaletti, Lynn R. Gauthier, Michael P. McDermott, Nimish Mohile, Supriya G. Mohlie, A. Gordon Smith, Mohamedtaki Abdulaziz Tejani, Dennis C. Turk, Robert H. Dworkin

The Potential Role of Sensory Testing, Skin Biopsy, and Functional Brain Imaging as Biomarkers in Chronic Pain Clinical Trials: IMMPACT Considerations

Shannon M. Smith, Robert H. Dworkin, Dennis C. Turk, Ralf Baron, Michael Polydefkis, Irene Tracey, David Borsook, Robert R. Edwards, Richard E. Harris, Tor D. Wager, Lars Arendt-Nielsen, Laurie B. Burke, Daniel B. Carr, Amy S. Chappell, John T. Farrar, Roy Freeman, Ian Gilron, Veeraindar Goli, Juergen Haeussler, Troels S. Jensen, Nathaniel P. Katz, Jeffrey Kent, Ernest A. Kopecky, David A. Lee, William Maixner, John D. Markman, Justin C. McArthur, Michael P. McDermott, Lav K. Parvathenani, Srinivasa N. Raja, Bob A. Rappaport, Andrew S.C. Rice, Michael C. Rowbotham, Jeffrey Tobias, Ajay D. Wasan, James Witter

Autonomic and electrocardiographic findings in Parkinson’s disease

Christopher H. Gibbons, David Simon, Meilin Huang, Barbara C. Tilley, Michael J. Aminoff, Jacquelyn L. Bainbridge, Matthew Brodsky, Roy Freeman, John L. Goudreau, Robert W. Hamill, Sheng Luo, Carlos Singer, Aleksandar Videnovic, Ivan Bodis-Wollner, Pei S. Wong

Cutaneous Autonomic Pilomotor Testing to Unveil the Role of Neuropathy Progression in Early Parkinson's Disease (CAPTURE PD): Protocol for a Multicenter Study.

Timo Siepmann, Alexandra Pinter, Sylvia J. Buchmann, Leonie Stibal, Martin Arndt, Anne Sophie Kubasch, Marie Luise Kubasch, Ana Isabel Penzlin, Elka Frenz, Wagner Zago, Tamas L. Horvath, Szabolcs Szatmári, Dániel Bereczki, Annamária Takáts, Tjalf Ziemssen, Axel Lipp, Roy Freeman, Heinz Reichmann, Kristian Barlinn, Ben Min-Woo Illigens

Enhanced Cholinergic Activity Improves Cerebral Blood Flow during Orthostatic Stress

Jorge M. Serrador, Roy Freeman

Content validity of symptom‐based measures for diabetic, chemotherapy, and HIV peripheral neuropathy

Jennifer S. Gewandter, Laurie B. Burke, Guido Cavaletti, Robert H. Dworkin, Christopher H. Gibbons, Tony D. Gover, David N. Herrmann, Justin C. McArthur, Michael P. McDermott, Bob A. Rappaport, Bryce B. Reeve, James W. Russell, A. Gordon Smith, Shannon M. Smith, Dennis C. Turk, Aaron I. Vinik, Roy Freeman

Do we need to evaluate diastolic blood pressure in patients with suspected orthostatic hypotension

Artur Fedorowski, Viktor Hamrefors, Richard Sutton, J. Gert van Dijk, Roy Freeman, Jacques W.M. Lenders, Wouter Wieling

Neuropathic pain.

Luana Colloca, Taylor Ludman, Didier Bouhassira, Ralf Baron, Anthony H Dickenson, David Yarnitsky, Roy Freeman, Andrea Truini, Nadine Attal, Nanna B Finnerup, Christopher Eccleston, Eija Kalso, David L Bennett, Robert H Dworkin, Srinivasa N Raja

Natural history of pure autonomic failure: A United States prospective cohort.

Horacio Kaufmann, Lucy Norcliffe-Kaufmann, Jose-Alberto Palma, Italo Biaggioni, Phillip A. Low, Wolfgang Singer, David S. Goldstein, Amanda Peltier, Cyndia A Shibao, Christopher H. Gibbons, Roy Freeman, David Robertson

Effects of orthostatic hypotension on cognition in Parkinson disease

Justin Centi, Roy Freeman, Christopher H. Gibbons, Sandy Neargarder, Alexander O. Canova, Alice Cronin-Golomb

The recommendations of a consensus panel for the screening, diagnosis, and treatment of neurogenic orthostatic hypotension and associated supine hypertension

Christopher H. Gibbons, Peter Schmidt, Italo Biaggioni, Camille Frazier-Mills, Roy Freeman, Stuart Isaacson, Beverly Karabin, Louis Kuritzky, Mark F. Lew, Phillip A. Low, Ali Mehdirad, Satish R. Raj, Steven Vernino, Horacio Kaufmann

Cutaneous Alpha-Synuclein From Paraffin Embedded Autopsy Specimens in Parkinson’s Disease

Christopher H. Gibbons, Ningshan Wang, Roy Freeman

The Search for a Peripheral Biopsy Indicator of α-Synuclein Pathology for Parkinson Disease.

John M. Lee, Pascal Derkinderen, Jeffrey H. Kordower, Roy Freeman, David G. Munoz, Thomas Kremer, Wagner Zago, Samantha J. Hutten, Charles H. Adler, Geidy E. Serrano, Thomas G. Beach

Diabetic Neuropathy: A Position Statement by the American Diabetes Association

Rodica Pop-Busui, Andrew J.M. Boulton, Eva L. Feldman, Vera Bril, Roy Freeman, Rayaz A. Malik, Jay M. Sosenko, Dan Ziegler

Reply.

Jennifer S Gewandter, Robert H Dworkin, Nanna B Finnerup, Roy Freeman, Nimish A Mohile

Assessment of physical function and participation in chronic pain clinical trials: IMMPACT/OMERACT recommendations

Ann Margaret Taylor, Kristine Phillips, Kushang V. Patel, Dennis C. Turk, Robert H. Dworkin, Dorcas E. Beaton, Daniel J. Clauw, Monique A. M. Gignac, John D. Markman, David A. Williams, Shay Bujanover, Laurie B. Burke, Daniel B. Carr, Ernest Choy, Philip G. Conaghan, Penney Cowan, John T. Farrar, Roy Freeman, Jennifer S. Gewandter, Ian Gilron, Veeraindar Goli, Tony D. Gover, J. David Haddox, Robert D. Kerns, Ernest A. Kopecky, David A. Lee, Richard Malamut, Philip J. Mease, Bob A. Rappaport, Lee S. Simon, Jasvinder A. Singh, Shannon M. Smith, Vibeke Strand, Peter Tugwell, Gertrude F. Vanhove, Christin Veasley, Gary A. Walco, Ajay D. Wasan, James Witter

Pain in acquired inflammatory demyelinating polyneuropathies.

Siddarth Thakur, Robert H. Dworkin, Roy Freeman, Kenneth C. Gorson, David N. Herrmann

Patient phenotyping in clinical trials of chronic pain treatments: IMMPACT recommendations.

Robert R. Edwards, Robert H. Dworkin, Dennis C. Turk, Martin S. Angst, Raymond A. Dionne, Roy Freeman, Per Hansson, Simon Haroutounian, Lars Arendt-Nielsen, Nadine Attal, R. Baron, Joanna M. Brell, Shay Bujanover, Laurie B. Burke, Daniel B. Carr, Amy S. Chappell, Penney Cowan, Mila Etropolski, Roger B. Fillingim, Jennifer S. Gewandter, Nathaniel P. Katz, Ernest A. Kopecky, John D. Markman, George G. Nomikos, Linda Porter, Bob A. Rappaport, Andrew S.C. Rice, Joseph M. Scavone, Joachim Scholz, Lee S. Simon, Shannon M. Smith, Jeffrey Tobias, Tina Tockarshewsky, Christine Veasley, Mark Versavel, Ajay D. Wasan, Warren Wen, David Yarnitsky

Blood pressure oscillations in baroreflex failure.

Ahmad R. Abuzinadah, Dong In Sinn, Roy Freeman, Christopher H. Gibbons

The diagnostic discrimination of cutaneous α-synuclein deposition in Parkinson disease

Christopher H. Gibbons, Jennifer Garcia, Ningshan Wang, Ludy C. Shih, Roy Freeman

Neuropathic pain: An updated grading system for research and clinical practice

Nanna B. Finnerup, Simon Haroutounian, Peter R. Kamerman, Ralf Baron, David L.H. Bennett, Didier Bouhassira, Giorgio Cruccu, Roy Freeman, Per Hansson, Turo Nurmikko, Srinivasa N. Raja, Andrew S.C. Rice, Jordi Serra, Blair H. Smith, Rolf-Detlef Treede, Troels S. Jensen

Predictors of improvement and progression of diabetic polyneuropathy following treatment with α-lipoic acid for 4 years in the NATHAN 1 trial.

Dan Ziegler, Phillip A. Low, Roy Freeman, H. J. Tritschler, Aaron I. Vinik

Neuropathic pain phenotyping by international consensus (NeuroPPIC) for genetic studies: a NeuPSIG systematic review, Delphi survey, and expert panel recommendations.

Oliver van Hecke, Peter R. Kamerman, Nadine Attal, Ralf Baron, Gyda Bjornsdottir, David L.H. Bennett, Michael I. Bennett, Didier Bouhassira, Luda Diatchenko, Roy Freeman, Rainer Freynhagen, Maija Haanpää, Troels S. Jensen, Srinivasa N. Raja, Andrew S.C. Rice, Zeʼev Seltzer, Thorgeir E. Thorgeirsson, David Yarnitsky, Blair H. Smith

Clinical implications of delayed orthostatic hypotension A 10-year follow-up study

Christopher H. Gibbons, Roy Freeman

Relationships Among Pain Quality, Pain Impact, and Overall Improvement in Patients with Postherpetic Neuralgia Treated with Gastroretentive Gabapentin

Roy Freeman, Mark S. Wallace, Michael O. Sweeney, M. Backonja

Recent advances in familial amyloid polyneuropathy.

Roy Freeman, Fabio Barroso

Baroreflex Sensitivity Impairment During Hypoglycemia: Implications for Cardiovascular Control

Ajay D. Rao, Istvan Bonyhay, Joel Dankwa, Maria Baimas-George, Lindsay Kneen, Sarah Ballatori, Roy Freeman, Gail K. Adler

Autonomic Neuropathy.

Jennifer Dineen, Roy Freeman

Fluid biomarkers in multiple system atrophy: A review of the MSA Biomarker Initiative

Brice Laurens, Radu Constantinescu, Roy Freeman, Alexander Gerhard, Kurt A. Jellinger, Andreas Jeromin, Florian Krismer, Brit Mollenhauer, Michael G. Schlossmacher, Leslie M. Shaw, Marcel M. Verbeek, Gregor K. Wenning, Kristian Winge, Jing Zhang, Wassilios G. Meissner

Predictors of placebo response in peripheral neuropathic pain: insights from pregabalin clinical trials

Roy Freeman, Birol Emir, Bruce Parsons

The puzzle of orthostatic tolerance in hereditary sensory and autonomic neuropathy, type IV

Roy Freeman

Treatment-induced neuropathy of diabetes: an acute, iatrogenic complication of diabetes

Christopher H. Gibbons, Roy Freeman

Randomized Withdrawal Study of Patients With Symptomatic Neurogenic Orthostatic Hypotension Responsive to Droxidopa

Italo Biaggioni, Roy Freeman, Christopher J. Mathias, Phillip A. Low, L. Arthur Hewitt, Horacio Kaufmann

Designing innovative therapies for neuropathic pain: preclinical and early clinical development challenges

Ahmet Hoke, David M. Simpson, Roy Freeman

Journal of the Peripheral Nervous System. Supplement: Designing innovative therapies for neuropathic pain: 2014 FPN International Research Symposium. Introduction

Ahmet Hoke, D. M. Simpson, R. Freeman

Droxidopa for neurogenic orthostatic hypotension A randomized, placebo-controlled, phase 3 trial

Horacio Kaufmann, Roy Freeman, Italo Biaggioni, Phillip A. Low, Simon Pedder, L. Arthur Hewitt, Joe Mauney, Michael Feirtag, Christopher J. Mathias

The ACTTION-American Pain Society Pain Taxonomy (AAPT): An Evidence-Based and Multidimensional Approach to Classifying Chronic Pain Conditions

Roger B. Fillingim, Stephen Bruehl, Robert H. Dworkin, Samuel F. Dworkin, John D. Loeser, Dennis C. Turk, Eva Widerström-Noga, Lesley M. Arnold, Robert M. Bennett, Robert R. Edwards, Roy Freeman, Jennifer S. Gewandter, Sharon Hertz, Marc C. Hochberg, Elliot J. Krane, Patrick W. Mantyh, John D. Markman, Tuhina Neogi, Richard Ohrbach, Judith A. Paice, Frank Porreca, Bob A. Rappaport, Shannon M. Smith, Thomas J. Smith, Mark Sullivan, G. Nicholas Verne, Ajay D. Wasan, Ursula Wesselmann

Efficacy and safety of rifampicin for multiple system atrophy: a randomised, double-blind, placebo-controlled trial

Phillip A. Low, David Robertson, Sid Gilman, Horacio Kaufmann, Wolfgang Singer, Italo Biaggioni, Roy Freeman, Susan Perlman, Robert A. Hauser, William P. Cheshire, Stephanie Lessig, Steven Vernino, Jay Mandrekar, William D. Dupont, Thomas C. Chelimsky, Wendy R. Galpern

Endovascular procedures for the treatment of autonomic dysfunction.

Christopher H. Gibbons, William P. Cheshire, Alexandru Barboi, Benjamin D. Levine, Brian Olshansky, Laurence J. Kinsella, Victoria E. Claydon, Craig G. Crandall, Gregory D. Fink, Michael J. Joyner, Vaughan G. Macefield, Lucy Norcliffe-Kaufmann, Roy Freeman, Satish R. Raj, Julian M. Stewart, Paola Sandroni, Horacio Kaufmann, Thomas C. Chelimsky

Sensory profiles of patients with neuropathic pain based on the neuropathic pain symptoms and signs

Roy Freeman, Ralf Baron, Didier Bouhassira, Javier Cabrera, Birol Emir

Diabetic autonomic neuropathy.

Roy Freeman

Structural and Functional Small Fiber Abnormalities in the Neuropathic Postural Tachycardia Syndrome

Christopher H. Gibbons, Istvan Bonyhay, Adam Benson, Ningshan Wang, Roy Freeman

A Phase 2a, Randomized, Crossover Trial of Gabapentin Enacarbil for the Treatment of Postherpetic Neuralgia in Gabapentin Inadequate Responders

R. Norman Harden, Roy Freeman, Michelle Rainka, Lixin Zhang, Christopher F. Bell, Alienor Berges, Chao Chen, Ole Graff, Kathleen Harding, Setrina Hunter, Sarah Kavanagh, Caryl Schwartzbach, Samantha Warren, Carrie McClung

High-Pass Filter Characteristics of the Baroreflex – A Comparison of Frequency Domain and Pharmacological Methods

Istvan Bonyhay, Marcelo Risk, Roy Freeman

α-Synuclein in cutaneous autonomic nerves

Ningshan Wang, Christopher H. Gibbons, Jacob Lafo, Roy Freeman

Non-invasive brain stimulation and the autonomic nervous system

Pedro Schestatsky, Marcel Simis, Roy Freeman, Alvaro Pascual-Leone, Felipe Fregni

Value of quantitative sensory testing in neurological and pain disorders: NeuPSIG consensus.

Miroslav Backonja, Nadine Attal, Ralf Baron, Didier Bouhassira, Mark Drangholt, Peter J. Dyck, Robert R. Edwards, Roy Freeman, Richard H. Gracely, Maija H. Haanpaa, Per Hansson, Samar Hatem, Elena K. Krumova, Troels S. Jensen, Christoph Maier, Gérard Mick, Andrew S.C. Rice, Roman Rolke, Rolf-Detlef Treede, Jordi Serra, Thomas R Toelle, Valeri Tugnoli, David Walk, Mark S. Walalce, Mark A. Ware, David Yarnitsky, Dan Ziegler

New and developing drugs for the treatment of neuropathic pain in diabetes.

Roy Freeman

A randomized, double-blind, placebo-controlled trial to assess the efficacy and safety of gabapentin enacarbil in subjects with neuropathic pain associated with postherpetic neuralgia (PXN110748).

Lixin Zhang, Michelle Rainka, Roy Freeman, R. Norman Harden, Christopher F. Bell, Chao Chen, Ole Graff, Kathleen Harding, Setrina Hunter, Sarah Kavanagh, Bart Laurijssens, Caryl Schwartzbach, Samantha Warren, Carrie McClung

The evolving natural history of neurophysiologic function in patients with well-controlled diabetes.

Christopher H. Gibbons, Roy Freeman, Francisco Tecilazich, Thanh Dinh, Thomas E. Lyons, Charalambos Gnardellis, Aristidis Veves

Challenges in developing novel therapies for peripheral neuropathies: a summary of The Foundation for Peripheral Neuropathy Scientific Symposium 2012.

Ahmet Hoke, David M. Simpson, Roy Freeman

Objective Evidence of Autonomic Dysfunction and the Role of Stress in the Gulf War Syndrome

Roy Freeman

Testing the autonomic nervous system

Roy Freeman, Mark W. Chapleau

Quantitative pilomotor axon reflex test: a novel test of pilomotor function.

Timo Siepmann, Christopher H. Gibbons, Ben Min-Woo Illigens, Jacob Lafo, Christopher M. Brown, Roy Freeman

Experimental hypoglycemia is a human model of stress-induced hyperalgesia

Christopher H. Gibbons, Gail K. Adler, Istvan Bonyhay, Roy Freeman

Highlights in clinical autonomic neurosciences: Orthostatic hypotension: insights into risks and causes.

Satish R. Raj, Roy Freeman

Highlights in clinical autonomic neuroscience: latest discoveries from the octopus pot.

William P. Cheshire, Roy Freeman

Highlights in clinical autonomic neurosciences: vasovagal syncope - insights on diagnosis, pathophysiology and treatment.

Satish R. Raj, Roy Freeman

Highlights in clinical autonomic neuroscience: latest developments in the early detection of diabetic autonomic neuropathy.

William P. Cheshire, Roy Freeman

Autoimmune Autonomic Ganglionopathy With Reversible Cognitive Impairment

Christopher H. Gibbons, Justin Centi, Steven Vernino, Roy Freeman

The Orthostatic Hypotension Questionnaire (OHQ): validation of a novel symptom assessment scale

Horacio Kaufmann, Richard Malamut, Lucy Norcliffe-Kaufmann, Kathleen Rosa, Roy Freeman

Methods of investigation for cardiac autonomic dysfunction in human research studies

Luciano Bernardi, Vincenza Spallone, Martin J. Stevens, Jannik Hilsted, Simona Frontoni, Rodica Pop-Busui, Dan Ziegler, Péter Kempler, Roy Freeman, Phillip A. Low, Solomon Tesfaye, Paul Valensi

Management strategies for gastrointestinal, erectile, bladder, and sudomotor dysfunction in patients with diabetes

Péter Kempler, G. Amarenco, Roy Freeman, Simona Frontoni, Michael Horowitz, Martin J. Stevens, Phillip A. Low, Rodica Pop-Busui, Abd A. Tahrani, Solomon Tesfaye, Tamás Várkonyi, Dan Ziegler, Paul Valensi

Cardiovascular autonomic neuropathy in diabetes: clinical impact, assessment, diagnosis, and management

Vincenza Spallone, Dan Ziegler, Roy Freeman, Luciano Bernardi, Simona Frontoni, Rodica Pop-Busui, Martin J. Stevens, Péter Kempler, Jannik Hilsted, Solomon Tesfaye, Phillip A. Low, Paul Valensi

Efficacy and Safety of Antioxidant Treatment With α-Lipoic Acid Over 4 Years in Diabetic Polyneuropathy: The NATHAN 1 trial

Dan Ziegler, Phillip A. Low, William J. Litchy, Andrew J.M. Boulton, Aaron I. Vinik, Roy Freeman, Rustem Samigullin, Hans J. Tritschler, Ullrich Munzel, Joachim Maus, Klemens Schütte, Peter J. Dyck

Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome

Roy Freeman, W. Wieling, Felicia B. Axelrod, David G. Benditt, Eduardo E. Benarroch, Italo Biaggioni, William P. Cheshire, Thomas C. Chelimsky, Pietro Cortelli, Christopher H. Gibbons, David S. Goldstein, Roger Hainsworth, Max J. Hilz, Giris Jacob, Horacio Kaufmann, Jens Jordan, Lewis A. Lipsitz, Benjamin D. Levine, Phillip A. Low, Christopher J. Mathias, Satish R. Raj, David Robertson, Paola Sandroni, Irwin J. Schatz, Ron Schondorf, Julian M. Stewart, J. Gert van Dijk

Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome.

Roy Freeman, W. Wieling, Felicia B. Axelrod, David G. Benditt, Eduardo E. Benarroch, Italo Biaggioni, William P. Cheshire, Thomas C. Chelimsky, Pietro Cortelli, Christopher H. Gibbons, David S. Goldstein, Roger Hainsworth, Max J. Hilz, Giris Jacob, Horacio Kaufmann, Jens Jordan, Lewis A. Lipsitz, Benjamin D. Levine, Phillip A. Low, Christopher J. Mathias, Satish R. Raj, David Robertson, Paola Sandroni, Irwin J. Schatz, Ron Schondorff, Julian M. Stewart, J. Gert van Dijk

Novel Immunohistochemical Techniques Using Discrete Signal Amplification Systems for Human Cutaneous Peripheral Nerve Fiber Imaging

Ningshan Wang, Christopher H. Gibbons, Roy Freeman

Capsaicin induces degeneration of cutaneous autonomic nerve fibers

Christopher H. Gibbons, Ningshan Wang, Roy Freeman

Diabetic Neuropathy: A cross sectional study of the relationships among tests of neurophysiology

Christopher H. Gibbons, Roy Freeman, Aristidis Veves

Hypoglycaemia increases aldosterone in a dose-dependent fashion

Gail K. Adler, Istvan Bonyhay, V. Curren, E. Waring, Roy Freeman

Diabetic Neuropathies: Update on Definitions, Diagnostic Criteria, Estimation of Severity, and Treatments

Solomon Tesfaye, Andrew J.M. Boulton, Peter J. Dyck, Roy Freeman, Michael Horowitz, Péter Kempler, Giuseppe Lauria, Rayaz A. Malik, Vincenza Spallone, Aaron I. Vinik, Luciano Bernardi, Paul Valensi

Quantification of sudomotor innervation: A comparison of three methods

Christopher H. Gibbons, Ben Min-Woo Illigens, Ningshan Wang, Roy Freeman

Treatment‐induced diabetic neuropathy: A reversible painful autonomic neuropathy

Christopher H. Gibbons, Roy Freeman

Pregabalin for painful HIV neuropathy: a randomized, double-blind, placebo-controlled trial.

David M. Simpson, Giovanni Schifitto, David B. Clifford, T.K. Murphy, E. Durso-De Cruz, Paul Glue, Ed Whalen, Birol Emir, G. N. Scott, Roy Freeman

Not all neuropathy in diabetes is of diabetic etiology: Differential diagnosis of diabetic neuropathy

Roy Freeman

Quantification of sweat gland innervation: a clinical-pathologic correlation.

Christopher H. Gibbons, Ben Min-Woo Illigens, Ningshan Wang, Roy Freeman

Antibody titers predict clinical features of autoimmune autonomic ganglionopathy.

Christopher H. Gibbons, Roy Freeman

Antecedent hypoglycemia impairs autonomic cardiovascular function - implications for rigorous glycemic control

Gail K. Adler, Istvan Bonyhay, Hannah J. Failing, Elizabeth Waring, Sarah Dotson, Roy Freeman

Phantom sweating: a novel autonomic paresthesia

L. Lair, Christopher H. Gibbons, Roy Freeman

Efficacy, safety, and tolerability of pregabalin treatment for painful diabetic peripheral neuropathy: findings from seven randomized, controlled trials across a range of doses.

Roy Freeman, Edith Durso-DeCruz, Birol Emir

QDIRT: Quantitative direct and indirect test of sudomotor function

Christopher H. Gibbons, Ben Min-Woo Illigens, Justin Centi, Roy Freeman

Hypoglycemia increases serum interleukin-6 levels in healthy men and women.

Sarah Dotson, Roy Freeman, Hannah J. Failing, Gail K. Adler

Neurogenic orthostatic hypotension.

Mark Joy

Current pharmacologic treatment for orthostatic hypotension

Roy Freeman

A treatment for neurally mediated syncope? (Don't) hold your breath.

Roy Freeman

Neurogenic Orthostatic Hypotension

Roy Freeman

Combined immunomodulatory therapy in autoimmune autonomic ganglionopathy.

Christopher H. Gibbons, Steven Vernino, Roy Freeman

Two styles of acupuncture for treating painful diabetic neuropathy--a pilot randomised control trial.

Andrew C. Ahn, Taher Bennani, Roy Freeman, Osama Hamdy, Ted J. Kaptchuk

Topiramate and physiologic measures of nerve function in polyneuropathy

Roy Freeman, K. A. McIntosh, U. Vijapurkar, U. Thienel

Sympathetic neural activity, sex dimorphism, and postural tachycardia syndrome

Istvan Bonyhay, Roy Freeman

Surgical decompression for diabetic sensorimotor polyneuropathy.

David R. Cornblath, Aaron I. Vinik, Eva L. Feldman, Roy Freeman, Andrew J.M. Boulton

Autonomic Peripheral Neuropathy

Roy Freeman

Randomized study of tramadol/acetaminophen versus placebo in painful diabetic peripheral neuropathy.

Roy Freeman, Philip Raskin, David J. Hewitt, G. Vorsanger, Donna Jordan, Jim Xiang, Norman R. Rosenthal

The ACCF/AHA scientific statement on syncope: A document in need of thoughtful revision

David G. Benditt, Wouter Wieling, Brian Olshansky, Haruhiko Abe, Paolo Alboni, Dietrich Andresen, Felicia B. Axelrod, Eduardo E Bennaroch, Lennart Bergfeldt, Jean Jacques Blanc, Michele Brignole, A. John Camm, Thomas C. Chelimsky, Pietro Cortelli, J. Gert van Dijk, Nynke van Dijk, Murray D. Esler, A. P. Fitzpatrick, Fetnat M. Fouad-Tarazi, Roy Freeman, Mary Ann Goldstein, Blair P. Grubb, Bengt Herweg, Max J. Hilz, Giris Jacob, David L. Jardine, Jens Jordan, Michael J. Joyner, Wishwa N. Kapoor, Horacio Kaufmann, Rose Anne Kenny, Andrew D. Krahn, Chu Pak Lau, Benjamin D. Levine, Johannes J. van Lieshout, Lewis A. Lipsitz, Philip A. Low, Keith G. Lurie, Marek Malik, Christopher J. Mathias, Angel Moya, Satish R. Raj, Antonio Raviele, Sanjeev Saksena, François Sarasin, Philip J. Saul, Ronald Schondorf, Jean-Michel Senard, Robert S. Sheldon, Win Kuang Shen, Jasbir Sra, John Stephenson, Julian M. Stewart, Richard Sutton, Hidetaka Tanaka, George Theodorakis, Roland D. Thijs, Andrea Ungar, Arthur A.M. Wilde

Delayed orthostatic hypotension: a frequent cause of orthostatic intolerance.

Christopher H. Gibbons, Roy Freeman

Assessment of cardiovascular autonomic function.

Roy Freeman

Differential impairment of the sudomotor and nociceptor axon-reflex in diabetic peripheral neuropathy.

Martin Berghoff, Sonja Kilo, Max J. Hilz, Roy Freeman

Treatment options for autonomic neuropathies

Christopher H. Gibbons, Roy Freeman

Diagnosis and Treatment of Chronic Immune-mediated Neuropathies.

Norman Latov, Kenneth C. Gorson, Thomas H. Brannagan, Roy Freeman, Slobodan Apostolski, Alan R. Berger, Walter G. Bradley, Chiara Briani, Vera Bril, Neil A. Busis, Didier Cros, Marinos C. Dalakas, Peter D. Donofrio, P. James B. Dyck, John D. England, Morris A. Fisher, David N. Herrmann, Daniel L. Menkes, Zarife Sahenk, Howard W. Sander, William J. Triggs, Jean Michel Vallat

Cardiovascular manifestations of autonomic epilepsy.

Roy Freeman

Child coping strategies, dental anxiety and dental treatment: the influence of age, gender and childhood caries prevalence.

Van Meurs P, Howard KE, Versloot J, Veerkamp JSJ, Freeman R

Newer agents for the treatment of painful diabetic peripheral neuropathy

Roy Freeman

Is time of the essence? The continuing search for a noninvasive measure of sympathetic adrenergic function.

Roy Freeman, Christopher H. Gibbons

L-DOPS therapy for refractory orthostatic hypotension in autoimmune autonomic neuropathy.

Christopher H. Gibbons, Steven Vernino, Horacio Kaufmann, Roy Freeman

The Treatment of Neuropathic Pain

Roy Freeman

Autonomic peripheral neuropathy

Roy Freeman

Diabetic neuropathies: a statement by the American Diabetes Association.

Andrew J.M. Boulton, Arthur I. Vinik, Joseph C. Arezzo, Vera Bril, Eva L. Feldman, Roy Freeman, Rayaz A. Malik, Raelene E. Maser, Jay M. Sosenko, Dan Ziegler

Autonomic neuropathy and coeliac disease

Christopher H. Gibbons, Roy Freeman

Orthostatic dyspnea: a neglected symptom of orthostatic hypotension

Christopher H. Gibbons, Roy Freeman

Clinical pharmacokinetics of the norepinephrine precursor L-threo-DOPS in primary chronic autonomic failure.

David S. Goldstein, Courtney Holmes, Horacio Kaufmann, Roy Freeman

Sympathetic nerve activity in response to hypotensive stress in the postural tachycardia syndrome.

Istvan Bonyhay, Roy Freeman

Nonpharmacological treatment of reflex syncope.

Wouter Wieling, Nancy Colman, C T Paul Krediet, Roy Freeman

Pure autonomic failure: an immaculate misconception?

Roy Freeman

The evaluation of small fiber function-autonomic and quantitative sensory testing.

Christopher H. Gibbons, Roy Freeman

Assessment of cardiovascular autonomic function

Roy Freeman

Guidelines for the diagnosis and treatment of chronic inflammatory demyelinating polyneuropathy

Alan R. Berger, Walter G. Bradley, Thomas H. Brannagan, Neil A. Busis, Didier Cros, Marinos C. Dalakas, Moris J. Danon, Peter D. Donofrio, W. King Engel, John D. England, Eva L. Feldman, Roy Freeman, Laurence J. Kinsella, David Lacomis, Norman Latov, Daniel L. Menkes, Howard W. Sander, Florian P. Thomas, William J. Triggs, Anthony J. Windebank, Gil I. Wolfe

Diabetic autonomic neuropathy.

Aaron I. Vinik, Roy Freeman, Tomris Erbas

Treatment of orthostatic hypotension.

Roy Freeman

Disorders of sweating

William P. Cheshire, Roy Freeman

A biphasic model of limb venous compliance: a comparison with linear and exponential models

Marcelo Risk, Vasilios Lirofonis, Ricardo L. Armentano, Roy Freeman

Norepinephrine Precursor Therapy in Neurogenic Orthostatic Hypotension

Horacio Kaufmann, Daniela Saadia, Andrei Voustianiouk, David S. Goldstein, Courtney Holmes, Melvin D. Yahr, Rachel Nardin, Roy Freeman

Sphincter electromyography and multiple system atrophy.

Frederick Nahm, Roy Freeman

Endothelial dysfunction precedes C-fiber abnormalities in primary (AL) amyloidosis.

Martin Berghoff, Madeera Kathpal, Faisal Khan, Martha Skinner, Rodney H. Falk, Roy Freeman

The Association Between Cardiovascular Autonomic Neuropathy and Mortality in Individuals With Diabetes: A meta-analysis

Raelene E. Maser, Braxton D. Mitchell, Aaron I. Vinik, Roy Freeman

Diabetic Autonomic Neuropathy

Aaron I. Vinik, Raelene E. Maser, Braxton D. Mitchell, Roy Freeman

Quantitative sensory testing cannot differentiate simulated sensory loss from sensory neuropathy

Roy Freeman, Karen P. Chase, Marcelo Risk

Syncope and the history of nervous influences on the heart.

Frederick Nahm, Roy Freeman

Limb venous compliance in patients with idiopathic orthostatic intolerance and postural tachycardia.

Roy Freeman, Vasilios Lirofonis, William B. Farquhar, Marcelo Risk

The chronic fatigue syndrome is a disease of the autonomic nervous system. Sometimes.

Roy Freeman

High blood pressure and decreased heart rate variability in the Cuban epidemic neuropathy

J Gutierrez, R Santiesteban, H Garcia, Andrei Voustianiouk, Roy Freeman, Horacio Kaufmann

Spindle coma secondary to vasovagal syncope.

Maria Lopez, Roy Freeman, Donald L. Schomer

Vascular and neural mechanisms of ACh-mediated vasodilation in the forearm cutaneous microcirculation.

Martin Berghoff, Madeera Kathpal, Sonja Kilo, Max J. Hilz, Roy Freeman

Blood volume and its relation to peak O(2) consumption and physical activity in patients with chronic fatigue.

William B. Farquhar, Brian E. Hunt, J. Andrew Taylor, Stephen E. Darling, Roy Freeman

Vasovagal Syncope: The Contributions of Sir William R. Gowers and Sir Thomas Lewis

Frederick Nahm, Roy Freeman

Neural and perceptual adjustments to dim light.

Peterson M, Ohzawa I, Freeman R

Abnormal Baroreflex Responses in Patients With Idiopathic Orthostatic Intolerance

William B. Farquhar, J. Andrew Taylor, Stephen E. Darling, Karen P. Chase, Roy Freeman

Efficacy and Safety of Recombinant Human Nerve Growth Factor in Patients With Diabetic Polyneuropathy: A Randomized Controlled Trial

Apfel Sc, Sherwyn Schwartz, Adornato Bt, Roy Freeman, Biton, M. Rendell, Arthur I. Vinik, Giuliani M, Stevens Jc, Richard L. Barbano, Peter J. Dyck

Neural and endothelial control of the microcirculation in diabetic peripheral neuropathy

Sonja Kilo, Martin Berghoff, Max J. Hilz, Roy Freeman

The treatment of neurogenic orthostatic hypotension with 3,4-DL-threo-dihydroxyphenylserine: a randomized, placebo-controlled, crossover trial.

Roy Freeman, Lewis Landsberg, James B. Young

System identification of closed-loop cardiovascular control mechanisms: diabetic autonomic neuropathy

Ramakrishna Mukkamala, Joanne M. Mathias, Thomas J. Mullen, Richard J. Cohen, Roy Freeman

The importance of orthostatic intolerance in the chronic fatigue syndrome.

Ronald Schondorf, Roy Freeman

Human studies of recombinant human nerve growth factor and diabetic peripheral neuropathy.

Roy Freeman

Differences in foot and forearm skin microcirculation in diabetic patients with and without neuropathy.

Subodh Arora, Paula Smakowski, Robert G. Frykberg, Louis R. Simeone, Roy Freeman, Frank W. LoGerfo, Aristidis Veves

Endothelial dysfunction and the expression of endothelial nitric oxide synthetase in diabetic neuropathy, vascular disease, and foot ulceration.

Aristidis Veves, Cameron M. Akbari, James Primavera, Valerie M. Donaghue, Dimitrios Zacharoulis, J S Chrzan, Umberto DeGirolami, Frank W. LoGerfo, Roy Freeman

Complexity of middle cerebral artery blood flow velocity: effects of tilt and autonomic failure

Andrew P. Blaber, R. L. Bondar, Flo Stein, Paul T. Dunphy, Peyman Moradshahi, Mahmood S. Kassam, Roy Freeman

Transfer Function Analysis of Cerebral Autoregulation Dynamics in Autonomic Failure Patients

Andrew P. Blaber, R. L. Bondar, Flo Stein, Paul T. Dunphy, Peyman Moradshahi, Mahmood S. Kassam, Roy Freeman

Cerebrovascular and Cardiovascular Responses to Graded Tilt in Patients With Autonomic Failure

R. L. Bondar, Paul T. Dunphy, Peyman Moradshahi, Mahmood S. Kassam, Andrew P. Blaber, Flo Stein, Roy Freeman

Efficacy of Midodrine for Neurogenic Orthostatic Hypotension-Reply

Phillip A. Low, Janice L Gilden, Roy Freeman, Sheng Ke-Ning, Mary Ann McElligott

Cardiovascular autonomic tests in diabetic patients with gastroparesis

Leila Maria Batista Araújo, Roy Freeman, Christoferson Broadbridge

Efficacy of midodrine vs placebo in neurogenic orthostatic hypotension. A randomized, double-blind multicenter study. Midodrine Study Group.

Phillip A. Low, Janice L Gilden, Roy Freeman, Ke Ning Sheng, Mary Ann McElligott

Does the Chronic Fatigue Syndrome Involve the Autonomic Nervous System

Roy Freeman, Anthony L. Komaroff

The treatment of postprandial hypotension in autonomic failure with 3,4-DL-threo-dihydroxyphenylserine

Roy Freeman, James B. Young, Lewis Landsberg, Lewis A. Lipsitz

Coarse graining spectral analysis of HR and BP variability in patients with autonomic failure

Andrew P. Blaber, R. L. Bondar, Roy Freeman

Myotonia in colchicine myoneuropathy

Seward B. Rutkove, Umberto De Girolami, David C. Preston, Roy Freeman, Rachel Nardin, Gunnar K. Gouras, Donald R. Johns, Elizabeth M. Raynor

Consensus statement on the definition of orthostatic hypotension, pure autonomic failure, and multiple system atrophy

Irwin J. Schatz, R. Bannister, Roy Freeman, Christopher G. Goetz, Joseph Jankovic, Horacio Kaufmann, William C. Koller, Phillip A. Low, Christopher J. Mathias, R. J. Polinsky, Niall Quinn, D. Robertson, D. H.P. Streeten

The relationship between heart rate variability and measures of body habitus

Roy Freeman, Scott T. Weiss, Mark S. Roberts, S M Zbikowski, David Sparrow

Autonomic epilepsy.

R Freeman, S C Schachter

Transfer function analysis of respiratory sinus arrhythmia: A measure of autonomic function in diabetic neuropathy

Roy Freeman, Richard J. Cohen, J.P. Saul

Effect of autonomic nervous system dysfunction on the circadian pattern of myocardial ischemia in diabetes mellitus

Stuart W. Zarich, Sergio Waxman, Roy Freeman, Murray A. Mittleman, Patricia Hegarty, Richard W. Nesto

Case 29-1994

Roy Freeman, David N. Louis

Determining heart-rate variability: comparing methodologies using computer simulations.

Jason D. Harry, Roy Freeman

Hemodynamic and autonomic nervous system responses to mixed meal ingestion in healthy young and old subjects and dysautonomic patients with postprandial hypotension.

Lewis A. Lipsitz, Stanthia Ryan, J.A.T.C. Parker, Roy Freeman, Jeanne Y. Wei, Ary L. Goldberger

The treatment of autonomic dysfunction.

Roy Freeman, Edison Miyawaki

Transcranial Doppler Assessment of the Cerebral Circulation during Postprandial Hypotension in the Elderly

Adam Krajewski, Roy Freeman, Robin Ruthazer, Margaret Kelley, Lewis A. Lipsitz

Autonomic neurodermatology (Part II): Disorders of sweating and flushing.

Roy Freeman, Heidi A. Waldorf, Jeffrey S. Dover

Autonomic neurodermatology (Part I): Erythromelalgia, reflex sympathetic dystrophy, and livedo reticularis.

Roy Freeman, Jeffrey S. Dover

Lovastatin/gemfibrozil myopathy: a clinical, histochemical, and ultrastructural study.

A. Chucrallah, U. De Girolami, Roy Freeman, M. Federman

Home monitoring of uterine activity. Does it prevent prematurity?

Sachs BP, Hellerstein S, Freeman R, Frigoletto F, Hauth JC

The treatment of orthostatic hypotension with dihydroxyphenylserine.

Roy Freeman, Lewis Landsberg

Spectral analysis of heart rate in diabetic autonomic neuropathy. A comparison with standard tests of autonomic function.

Roy Freeman, J.P. Saul, Mark S. Roberts, Ronald D. Berger, C Broadbridge, Richard J. Cohen

Can we lose memories of faces? content specificity and awareness in a prosopagnosic

Nancy L. Etcoff, Roy Freeman, Kyle R. Cave

Autonomic function and human immunodeficiency virus infection.

Roy Freeman, Mark S. Roberts, Lawrence S. Friedman, Christopher Broadbridge

Pseudallescheria boydii Infection of the Central Nervous System

Paul Kershaw, Roy Freeman, Dennis Templeton, Paola C. DeGirolami, Umberto DeGirolami, Daniel Tarsy, Steven Hoffmann, George M. Eliopoulos, Adolph W. Karchmer

Anti-Sympathetic Nervous System Autoantibodies Diminished Catecholamines With Orthostasis

Florence M. Brown, Stuart J Brink, Roy Freeman, Steven L. Rabinowe

Quantitative analysis of cerebral asymmetries. Fronto-occipital correlation, sexual dimorphism and association with handedness.

David M. Bear, David Schiff, Jeffrey L. Saver, Mark S. Greenberg, Roy Freeman

The neurology of depression. Cognitive and behavioral deficits with focal findings in depression and resolution after electroconvulsive therapy.

Roy Freeman, Albert M. Galaburda, Ramiro Diaz Cabal, Norman Geschwind

Syndrome of opsoclonus‐myoclons caused by coxsackie B3 infection

Karl C. Kuban, Moshe A. Ephros, Roy L. Freeman, Lori Burtz Laffell, Michael J. Bresnan

Transient ischemic attack and adriamycin cardiomyopathy

Steven C. Schachter, Roy Freeman

Malignant course of thyroid cancer.

Feder AS, Freeman R

Diabetic Peripheral Neuropathy: More Effective Treatments Needed

Diabetic Peripheral Neuropathy: More Effective Treatments Needed

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Neurologists diagnose and treat brain and nervous system disorders. Examples of medical conditions they treat include migraines, strokes, epilepsy, multiple sclerosis and sleep disorders, such as narcolepsy. See all conditions on Dr. Freeman's profile.

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Doctor's Details

Speaks English
Works at Beth Israel Deaconess Medical Center

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