Dr. Gregory D. Lewis MD

Effect of Inorganic Nitrite vs Placebo on Exercise Capacity Among Patients with Heart Failure with Preserved Ejection Fraction

Gregory D Lewis, David J Whellan, Martin M LeWinter, Margaret M Redfield, Andrew L Smith, Eugene Braunwald, Michael M Givertz, Adrian F Hernandez, Sanjiv J Shah, Horng H Chen, Barry A Borlaug, Kenneth B Margulies

The Effect of Donor Age on Post‐Transplant Mortality in a Cohort of Adult Cardiac Transplant Recipients Aged 18 to 45

Gregory D Lewis, Amy G Fiedler, Heidi Yeh

Heart Failure with Preserved Ejection Fraction Expert Panel Report

Kishan S Parikh, Howard K Surks, Sanjiv J Shah, Marvin A Konstam, Margaret M Redfield, Robert M Califf, Kavita Sharma, Narimon Honarpour, Gregory D Lewis, Scott D Solomon, Barry A Borlaug

Mini-Focus Issue: Exercise Performance and Cardiac Rehabilitation Relative Impairments in Hemodynamic Exercise Reserve Parameters in Heart Failure with Preserved Ejection Fraction: A Study-Level Pooled Analysis

Barry A Borlaug, Dalane W Kitzman, Rohan Khera, Gregory D Lewis, Javed Butler

An Official European Respiratory Society Statement: Pulmonary Haemodynamics During Exercise

Gregory Lewis, MD

Randomized Trial of a Selective Aldose Reductase Inhibitor in Patients With Diabetic Cardiomyopathy.

James L Januzzi Jr, Stefano Del Prato, Justin A Ezekowitz, Carolyn S P Lam, Thomas H Marwick, Riccardo Perfetti, W H Wilson Tang, Faiez Zannad, Javed Butler, Nasrien E Ibrahim, Gregory D Lewis, Julio Rosenstock, Scott D Solomon

Safety and Efficacy of Metabolic Modulation With Ninerafaxstat in Patients With Nonobstructive Hypertrophic Cardiomyopathy.

Martin S Maron, Masliza Mahmod, Azlan Helmy Abd Samat, Lubna Choudhury, Daniele Massera, Dermot M J Phelan, Sharon Cresci, Matthew W Martinez, Ahmad Masri, Theodore P Abraham, Eric Adler, Omar Wever-Pinzon, Sherif F Nagueh, Gregory D Lewis, Paul Chamberlin, Jai Patel, Arash Yavari, Hakim-Moulay Dehbi, Rizwan Sarwar, Betty Raman, Ladislav Valkovič, Stefan Neubauer, James E Udelson, Hugh Watkins

Spontaneous Improvement in Iron Parameters and the Relation With Changes in Functionality in Heart Failure.

Martens, P., Mullens, W., Tang, W., Lewis, G.

Hierarchical End Points in Prior Heart Failure Trials and the HEART-FID Trial.

Josephine Harrington, Robert J Mentz, Frank W Rockhold, Jyotsna Garg, Javed Butler, Carmine G De Pasquale, Justin A Ezekowitz, Gregory D Lewis, Eileen O'Meara, Piotr Ponikowski, Richard W Troughton, Yee W Wong, Robert Adamczyk, Tatyana Storie, Nicole Blackman, Adrian F Hernandez

Characterization and Prognostic Implications of Respirophasic Variation in Invasive Hemodynamic Measurements at Rest and With Exercise.

Campain, J., Giverts, I., Schoenicke, M., Sbarbaro, J., Griskowitz, C., Minasian, A., Prasad, C., Lewis, A., Shah, R., Lewis, G., Malhotra, R.

Exercise Capacity in Patients With Obstructive Hypertrophic Cardiomyopathy: SEQUOIA-HCM Baseline Characteristics and Study Design.

Caroline J Coats, Martin S Maron, Theodore P Abraham, Iacopo Olivotto, Matthew M Y Lee, Michael Arad, Nuno Cardim, Chang-Sheng Ma, Lubna Choudhury, Hans-Dirk Düngen, Pablo Garcia-Pavia, Albert A Hagège, Gregory D Lewis, Michelle Michels, Artur Oreziak, Anjali T Owens, Jacob Tfelt-Hansen, Josef Veselka, Hugh C Watkins, Stephen B Heitner, Daniel L Jacoby, Stuart Kupfer, Fady I Malik, Lisa Meng, Amy Wohltman, Ahmad Masri

Systemic Arterial Oxygen Levels Differentiate Pre- and Post-capillary Predominant Hemodynamic Abnormalities During Exercise in Undifferentiated Dyspnea on Exertion.

Kathryn M Hardin, Ilya Giverts, Joseph Campain, Robyn Farrell, Thomas Cunningham, Liana Brooks, Anastasia Christ, Luke Wooster, Cole S Bailey, Mark Schoenike, John Sbarbaro, Aaron Baggish, Matthew Nayor, Jennifer E Ho, Rajeev Malhotra, Ravi Shah, Gregory D Lewis

Acute rejection in donation after circulatory death (DCD) heart transplants.

Selena S Li, Masaki Funamoto, Asishana A Osho, Seyed A Rabi, Dane Paneitz, Ruby Singh, Eriberto Michel, Gregory D Lewis, David A D'Alessandro

Baseline characteristics of patients in the randomized study to investigate the efficacy and safety of ferric carboxymaltose as treatment for heart failure with iron deficiency: HEART-FID trial.

Josephine Harrington, Robert J Mentz, Frank W Rockhold, Jyotsna Garg, Javed Butler, Carmine G De Pasquale, Justin A Ezekowitz, Gregory D Lewis, Eileen O'Meara, Piotr Ponikowski, Richard W Troughton, Yee Weng Wong, Robert Adamczyk, Nicole Blackman, Adrian F Hernandez

Eicosanoid and eicosanoid-related inflammatory mediators and exercise intolerance in heart failure with preserved ejection fraction.

Lau, E., Roshandelpoor, A., Zarbafian, S., Wang, D., Guseh, J., Allen, N., Varadarajan, V., Nayor, M., Shah, R., Lima, J., Shah, S., Yu, B., Alotaibi, M., Cheng, S., Jain, M., Lewis, G., Ho, J.

Proteomics and Precise Exercise Phenotypes in Heart Failure With Preserved Ejection Fraction: A Pilot Study.

Ravi V Shah, Shih-Jen Hwang, Venkatesh L Murthy, Shilin Zhao, Kahraman Tanriverdi, Priya Gajjar, Kevin Duarte, Mark Schoenike, Robyn Farrell, Liana C Brooks, Deepa M Gopal, Jennifer E Ho, Nicholas Girerd, Ramachandran S Vasan, Daniel Levy, Jane E Freedman, Gregory D Lewis, Matthew Nayor

Arterial Stiffness and Cardiorespiratory Fitness Impairment in the Community.

Matthew Nayor, Priya Gajjar, Patricia Miller, Venkatesh L Murthy, Ravi V Shah, Nicholas E Houstis, Raghava S Velagaleti, Martin G Larson, Ramachandran S Vasan, Gregory D Lewis, Gary F Mitchell

Effect of Dapagliflozin on 6-Minute Walk Distance in Heart Failure With Preserved Ejection Fraction: PRESERVED-HF.

Gregory D Lewis, Kensey Gosch, Laura P Cohen, Michael E Nassif, Sheryl L Windsor, Barry A Borlaug, Dalane W Kitzman, Sanjiv J Shah, Taiyeb Khumri, Guillermo Umpierrez, Sumant Lamba, Kavita Sharma, Sadiya S Khan, Mikhail N Kosiborod, Andrew J Sauer

Obesity-Related Biomarkers Are Associated With Exercise Intolerance and HFpEF.

Mariana F Ramirez, Emily S Lau, Juhi K Parekh, Abigail S Pan, Ndidi Owunna, Dongyu Wang, Jenna N McNeill, Rajeev Malhotra, Matthew Nayor, Gregory D Lewis, Jennifer E Ho

Association of healthy dietary patterns and cardiorespiratory fitness in the community.

Michael Y Mi, Priya Gajjar, Maura E Walker, Patricia Miller, Vanessa Xanthakis, Venkatesh L Murthy, Martin G Larson, Ramachandran S Vasan, Ravi V Shah, Gregory D Lewis, Matthew Nayor

The association of eicosanoids and eicosanoid-related metabolites with pulmonary hypertension.

Jenna N McNeill, Athar Roshandelpoor, Mona Alotaibi, Arrush Choudhary, Mohit Jain, Susan Cheng, Shahrooz Zarbafian, Emily S Lau, Gregory D Lewis, Jennifer E Ho

Exercise-Induced Left Atrial Hypertension in Heart Failure With Preserved Ejection Fraction.

Chung, E., Gupta, D. K., Sheldon E Litwin, Jan Komtebedde, Mo Hu, Daniel Burkhoff, Gerd Hasenfuß, Barry A Borlaug, Scott D Solomon, Michael R Zile, Rajeev C Mohan, Rami Khawash, Aaron L Sverdlov, Peter Fail, Eugene S Chung, David M Kaye, John Blair, Jean-Christophe Eicher, Scott L Hummel, Andreas Zirlik, Ralf Westenfeld, Christopher Hayward, Thomas M Gorter, Catherine Demers, Ranjith Shetty, Gregory Lewis, Randall C Starling, Sanjay Patel, Deepak K Gupta, Hakim Morsli, Martin Penicka, Maja Cikes, Finn Gustafsson, Frank E Silvestry, Ethan J Rowin, Donald E Cutlip, Martin B Leon, Dalane W Kitzman, Franz X Kleber, Sanjiv J Shah

Iron Deficiency in Heart Failure: A Scientific Statement from the Heart Failure Society of America.

Craig J Beavers, Andrew P Ambrosy, Javed Butler, Beth T Davidson, Stormi E Gale, Ileana L Piña, Ioannis Mastoris, Nosheen Reza, Robert J Mentz, Gregory D Lewis

Cost-effectiveness of Sodium-Glucose Cotransporter-2 Inhibitors for the Treatment of Heart Failure With Preserved Ejection Fraction.

Laura P Cohen, Nicolas Isaza, Inmaculada Hernandez, Gregory D Lewis, Jennifer E Ho, Gregg C Fonarow, Dhruv S Kazi, Brandon K Bellows

Persistent Iron Deficiency and Dysregulated Hepcidin Levels After Durable Left Ventricular Assist Device Therapy.

Van-Khue Ton, Kamila Drezek, Sophie Boerboom, Katrina F Ostrom, Claire Birchenough, Janice Camuso, Tara Logan, Katherine Milley, Alexandra Anthony, Sunu S Thomas, Erin Coglianese, David D D'Alessandro, Rajeev Malhotra, Gregory D Lewis

Benefits of intravenous iron supplementation in patients with heart failure: mounting evidence and open questions.

Andreas P Kalogeropoulos, Gregory D Lewis

Characterization of ventilatory efficiency during cardiopulmonary exercise testing in healthy athletes.

Bradley J Petek, Timothy W Churchill, Sarah K Gustus, Mark W Schoenike, Matthew Nayor, Nathaniel Moulson, J Sawalla Guseh, Carolyn VanAtta, Jasmine B Blodgett, Miranda Contursi, Gregory D Lewis, Aaron L Baggish, Meagan M Wasfy

Phenomapping in heart failure with preserved ejection fraction: insights, limitations, and future directions.

Anthony E Peters, Jasper Tromp, Sanjiv J Shah, Carolyn S P Lam, Gregory D Lewis, Barry A Borlaug, Kavita Sharma, Ambarish Pandey, Nancy K Sweitzer, Dalane W Kitzman, Robert J Mentz

Invasive exercise haemodynamics: an oracle in heart failure with preserved ejection fraction diagnosis and prognostication.

Ioannis Mastoris, Joseph Campain, Gregory D Lewis

Rationale and design of the Aldose Reductase Inhibition for Stabilization of Exercise Capacity in Heart Failure Trial (ARISE-HF) in patients with high-risk diabetic cardiomyopathy.

James L Januzzi Jr, Javed Butler, Stefano Del Prato, Justin A Ezekowitz, Nasrien E Ibrahim, Carolyn S P Lam, Gregory D Lewis, Thomas H Marwick, Julio Rosenstock, W H Wilson Tang, Faiez Zannad, Francesca Lawson, Riccardo Perfetti, Alessia Urbinati

Blood Pressure Responses During Exercise: Physiological Correlates and Clinical Implications.

Matthew Nayor, Priya Gajjar, Venkatesh L Murthy, Patricia E Miller, Raghava S Velagaleti, Martin G Larson, Ramachandran S Vasan, Gregory D Lewis, Gary F Mitchell, Ravi V Shah

Hemodynamic and Clinical Performance of Hearts Donated After Circulatory Death.

David A D'Alessandro, Stanley B Wolfe, Asishana A Osho, Kamila Drezek, Monica N Prario, S Alireza Rabi, Eriberto Michel, Lana Tsao, Erin Coglianese, Meaghan Doucette, Daniel A Zlotoff, Christopher Newton-Cheh, Sunu S Thomas, Van-Khue Ton, Nilay Sutaria, Mark W Schoenike, Anastasia M Christ, Dane C Paneitz, Joren C Madsen, Richard Pierson, Gregory D Lewis

Diagnostic, prognostic and differential-diagnostic relevance of pulmonary haemodynamic parameters during exercise: a systematic review.

Katarina Zeder, Chiara Banfi, Gregor Steinrisser-Allex, Bradley A Maron, Marc Humbert, Gregory D Lewis, Andrea Berghold, Horst Olschewski, Gabor Kovacs

Heart Failure With Preserved Ejection Fraction as an Exercise Deficiency Syndrome: JACC Focus Seminar 2/4.

Andre La Gerche, Erin J Howden, Mark J Haykowsky, Gregory D Lewis, Benjamin D Levine, Jason C Kovacic

Blood-Based Fingerprint of Cardiorespiratory Fitness and Long-Term Health Outcomes in Young Adulthood.

Ravi V Shah, Patricia Miller, Laura A Colangelo, Ariel Chernofsky, Nicholas E Houstis, Rajeev Malhotra, Raghava S Velagaleti, David R Jacobs Jr, Kelley Pettee Gabriel, Jared P Reis, Donald M Lloyd-Jones, Clary B Clish, Martin G Larson, Ramachandran S Vasan, Venkatesh L Murthy, Gregory D Lewis, Matthew Nayor

The association of lung function and pulmonary vasculature volume with cardiorespiratory fitness in the community.

Jenna McNeill, Ariel Chernofsky, Matthew Nayor, Farbod N Rahaghi, Raul San Jose Estepar, George Washko, Andrew Synn, Ramachandran S Vasan, George O'Connor, Martin G Larson, Jennifer E Ho, Gregory D Lewis

Effect of Omecamtiv Mecarbil on Exercise Capacity in Chronic Heart Failure With Reduced Ejection Fraction: The METEORIC-HF Randomized Clinical Trial.

Gregory D Lewis, Adriaan A Voors, Alain Cohen-Solal, Marco Metra, David J Whellan, Justin A Ezekowitz, Michael Böhm, John R Teerlink, Kieran F Docherty, Renato D Lopes, Punag H Divanji, Stephen B Heitner, Stuart Kupfer, Fady I Malik, Lisa Meng, Amy Wohltman, G Michael Felker

Integrative Analysis of Circulating Metabolite Levels That Correlate With Physical Activity and Cardiorespiratory Fitness.

Matthew Nayor, Ariel Chernofsky, Patricia E Miller, Nicole L Spartano, Venkatesh L Murthy, Rajeev Malhotra, Nicholas E Houstis, Joanne M Murabito, Clary B Clish, Martin G Larson, Ramachandran S Vasan, Ravi V Shah, Gregory D Lewis

Developments in Exercise Capacity Assessment in Heart Failure Clinical Trials and the Rationale for the Design of METEORIC-HF.

Gregory D Lewis, Kieran F Docherty, Adriaan A Voors, Alain Cohen-Solal, Marco Metra, David J Whellan, Justin A Ezekowitz, Piotr Ponikowski, Michael Böhm, John R Teerlink, Stephen B Heitner, Stuart Kupfer, Fady I Malik, Lisa Meng, G Michael Felker

Exercise Blood Pressure in Heart Failure With Preserved and Reduced Ejection Fraction.

Mayooran Namasivayam, Emily S Lau, Emily K Zern, Mark W Schoenike, Kathryn M Hardin, John A Sbarbaro, Thomas F Cunningham, Robyn M Farrell, Jennifer Rouvina, Alyssa Kowal, Rohan R Bhat, Liana C Brooks, Matthew Nayor, Ravi V Shah, Jennifer E Ho, Rajeev Malhotra, Gregory D Lewis

Arterial Stiffness and Vascular Load in HFpEF: Differences Among Women and Men.

Emily S Lau, Lindsay G Panah, Emily K Zern, Elizabeth E Liu, Robyn Farrell, Mark W Schoenike, Mayooran Namasivayam, Timothy W Churchill, Lisa Curreri, Rajeev Malhotra, Matthew Nayor, Gregory D Lewis, Jennifer E Ho

Periodic Breathing in Cardiopulmonary Exercise Testing: Exercise Oscillatory Ventilation in Heart Failure.

Steven J Cassady, Danielle R Glick, Sarah R Williams, Gregory D Lewis

Unmasking Nonpreserved Heart Structure, Function, and Energetics in Heart Failure With Preserved Ejection Fraction With Magnetic Resonance Imaging Coupled With Exercise

Jennifer E. Ho, Christopher Nguyen, Gregory D. Lewis

Physical activity and fitness in the community: the Framingham Heart Study.

Matthew Nayor, Ariel Chernofsky, Nicole L. Spartano, Melissa Tanguay, Jasmine B Blodgett, Venkatesh L. Murthy, Rajeev Malhotra, Nicholas E. Houstis, Raghava S. Velagaleti, Joanne M. Murabito, Martin G. Larson, Ramachandran S. Vasan, Ravi V. Shah, Gregory D. Lewis

Exercise Ventricular Reserve Among Women With a History of Peripartum Cardiomyopathy

Evin Yucel, Esther F. Davis, Nandita S. Scott, Gregory D. Lewis, Doreen DeFaria Yeh

Effect of Treatment With Sacubitril/Valsartan in Patients With Advanced Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial.

Douglas L. Mann, Michael M. Givertz, Justin M. Vader, Randall C. Starling, Palak Shah, Steven McNulty, Kevin J. Anstrom, Kenneth B. Margulies, Michael S. Kiernan, Claudius Mahr, Divya Gupta, Margaret M. Redfield, Anuradha Lala, Gregory D. Lewis, Adam D. DeVore, Patrice Desvigne-Nickens, Adrian F. Hernandez, Eugene Braunwald, Life Investigators

Utility of the oxygen pulse in the diagnosis of obstructive coronary artery disease in physically fit patients.

Bradley J. Petek, Timothy W. Churchill, J. Sawalla Guseh, Garrett Loomer, Sarah K. Gustus, Gregory D. Lewis, Rory B. Weiner, Aaron L. Baggish, Meagan M. Wasfy

The SGLT2 inhibitor dapagliflozin in heart failure with preserved ejection fraction: a multicenter randomized trial.

Michael E. Nassif, Sheryl L. Windsor, Barry A. Borlaug, Dalane W. Kitzman, Sanjiv J. Shah, Fengming Tang, Yevgeniy Khariton, Ali O. Malik, Taiyeb M. Khumri, Guillermo E. Umpierrez, Sumant Lamba, Kavita Sharma, Sadiya S. Khan, Lokesh Chandra, Robert Gordon, John J. Ryan, Sunit-Preet Chaudhry, Susan M Joseph, Chen H Chow, Manreet Kanwar, Michael Pursley, Elias S. Siraj, Gregory D. Lewis, Barry S Clemson, Michael Fong, Mikhail Kosiborod

Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review.

Ambarish Pandey, Sanjiv J. Shah, Javed Butler, Dean L. Kellogg, Gregory D. Lewis, Daniel E. Forman, Robert J. Mentz, Barry A. Borlaug, Marc A. Simon, Julio A. Chirinos, Roger A. Fielding, Elena Volpi, Anthony J.A. Molina, Mark J. Haykowsky, Flora Sam, Bret H. Goodpaster, Alain G. Bertoni, Jamie N. Justice, James P. White, Jingzhone Ding, Scott L. Hummel, Nathan K. LeBrasseur, George E. Taffet, Iraklis I. Pipinos, Dalane W. Kitzman

Normative cardiopulmonary exercise data for endurance athletes: the Cardiopulmonary Health and Endurance Exercise Registry (CHEER).

Bradley J. Petek, Jason Tso, Timothy W. Churchill, J. Sawalla Guseh, Garrett Loomer, Milena DiCarli, Gregory D. Lewis, Rory B. Weiner, Jonathan H. Kim, Meagan M. Wasfy, Aaron L. Baggish

Exercise performance in patients with post-acute sequelae of SARS-CoV-2 infection compared to patients with unexplained dyspnea.

George A. Alba, David R. Ziehr, Jennifer N. Rouvina, Lida P. Hariri, Rachel S. Knipe, Benjamin D. Medoff, Kathryn A. Hibbert, Alyssa Kowal, Casey Hoenstine, Leo C. Ginns, Gregory D. Lewis, C. Corey Hardin

Management of Opioid Agonist Treatment for Opioid use Disorder in the Setting of Solid Organ Transplant.

Kayla Joyal, Alyssa M. Peckham, Sarah E. Wakeman, Daniel A. Zlotoff, Gregory D. Lewis, David A. D'Alessandro, Jerome C. Crowley, Georgina Waldman

Feasibility, Methodology, and Interpretation of Broad-Scale Assessment of Cardiorespiratory Fitness in a Large Community-Based Sample.

Matthew Nayor, Ravi V. Shah, Melissa Tanguay, Jasmine B Blodgett, Ariel Chernofsky, Patricia E. Miller, Vanessa Xanthakis, Rajeev Malhotra, Nicholas E. Houstis, Raghava S. Velagaleti, Martin G. Larson, Ramachandran S. Vasan, Gregory D. Lewis

Left Ventricular Assist Device Explant and Mitral Valve Replacement for Myocardial Recovery.

Van-Khue Ton, Sunu S. Thomas, Erin Coglianese, David A. D'Alessandro, Gregory D. Lewis

Vaccine serologic responses among transplant patients associate with COVID-19 infection and T peripheral helper cells

Jacob E. Lemieux, Amy Li, Matteo Gentili, Cory A. Perugino, Zoe Weiss, Kathryn Bowman, Pierre Ankomah, Hang Liu, Gregory D. Lewis, Natasha Bitar, Taryn Lipiner, Nir Hacohen, Shiv Pillai, Marcia B. Goldberg

Matrix Gla Protein Levels Are Associated With Arterial Stiffness and Incident Heart Failure With Preserved Ejection Fraction.

Rajeev Malhotra, Christopher J. Nicholson, Dongyu Wang, Vijeta Bhambhani, Samantha M. Paniagua, Charles Slocum, Haakon H. Sigurslid, Christian L. Lino Cardenas, Rebecca Li, Sophie L. Boerboom, Yin-Ching Chen, Shih-Jen Hwang, Chen Yao, Fumito Ichinose, Daniel Bloch, Mark E. Lindsay, Gregory D. Lewis, Jayashri Aragam, Udo Hoffmann, Gary F. Mitchell, Naomi M. Hamburg, Ramchandran S. Vasan, Emelia J. Benjamin, Martin G. Larson, Warren M. Zapol, Susan Cheng, Jason D. Roh, Christopher J. O'Donnell, Christopher Nguyen, Daniel Levy, Jennifer E. Ho

Metabolic Cost of Exercise Initiation in Patients With Heart Failure With Preserved Ejection Fraction vs Community-Dwelling Adults.

Ravi V. Shah, Mark W. Schoenike, Miguel Ángel Armengol de la Hoz, Thomas F Cunningham, Jasmine B Blodgett, Melissa Tanguay, John A. Sbarbaro, Matthew Nayor, Jennifer N. Rouvina, Alyssa Kowal, Nicholas E. Houstis, Aaron L. Baggish, Jennifer E. Ho, C. Corey Hardin, Rajeev Malhotra, Martin G. Larson, Ramachandran S. Vasan, Gregory D. Lewis

Exercise Oscillatory Ventilation in Hypertrophic Cardiomyopathy.

Stefanos G. Sakellaropoulos, Aaron L. Baggish, Michael A. Fifer, Gregory D. Lewis

Randomized Placebo-Controlled Trial of Ferric Carboxymaltose in Heart Failure With Iron Deficiency: Rationale and Design.

Robert J. Mentz, Andrew P. Ambrosy, Justin A. Ezekowitz, Gregory D. Lewis, Javed Butler, Yee Weng Wong, Carmine G. De Pasquale, Richard W. Troughton, Eileen O'Meara, Frank W. Rockhold, Jyostna Garg, Marc D. Samsky, Dianne Leloudis, Michael Dugan, Linda M. Mundy, Adrian F. Hernandez

Heart Failure with preserved ejection fraction according to the HFA-PEFF score in COVID-19 patients: clinical correlates and echocardiographic findings.

Sara Hadzibegovic, Alessia Lena, Timothy W. Churchill, Jennifer E. Ho, Sophia K. Potthoff, Corinna Denecke, Lukas Rösnick, Katrin Moira Heim, Malte Christian Kleinschmidt, Leif E. Sander, Martin Witzenrath, Norbert Suttorp, Alexander Krannich, Jan Porthun, Tim Friede, Javed Butler, Ursula Wilkenshoff, Burkert Pieske, Ulf Landmesser, Stefan D. Anker, Gregory D. Lewis, Carsten Tschöpe, Markus S. Anker

Free-breathing diffusion tensor MRI of the whole left ventricle using second-order motion compensation and multitasking respiratory motion correction.

Christopher Nguyen, Anthony G. Christodoulou, Jaume Coll-Font, Sen Ma, Yibin Xie, Timothy G. Reese, Choukri Mekkaoui, Gregory D. Lewis, Xiaoming Bi, David E. Sosnovik, Debiao Li

Association of obesity-related inflammatory pathways with lung function and exercise capacity.

Jenna McNeill, Emily S. Lau, Emily K. Zern, Matthew Nayor, Rajeev Malhotra, Elizabeth Liu, Rohan R Bhat, Liana Brooks, Robyn Farrell, John A. Sbarbaro, Mark W. Schoenike, Benjamin D. Medoff, Gregory D. Lewis, Jennifer E. Ho

Levosimendan Improves Hemodynamics and Exercise Tolerance in PH-HFpEF: Results of the Randomized Placebo-Controlled HELP Trial.

Daniel Burkhoff, Barry A. Borlaug, Sanjiv J. Shah, Ronald Zolty, Ryan J. Tedford, Thenappan Thenappan, Roham T. Zamanian, Jeremy A. Mazurek, Jonathan D. Rich, Marc A. Simon, Farhan Raza, David T. Majure, Gregory D. Lewis, Ioana R. Preston, Stuart Rich, Chung, E., Eugene S. Chung

A Phase II study of autologous mesenchymal stromal cells and c-kit positive cardiac cells, alone or in combination, in patients with ischaemic heart failure: the CCTRN CONCERT-HF trial.

Roberto Bolli, Raul D. Mitrani, Joshua M. Hare, Carl J. Pepine, Emerson C. Perin, James T. Willerson, Jay H. Traverse, Timothy D. Henry, Phillip C. Yang, Michael P. Murphy, Keith L. March, Ivonne Hernandez Schulman, Sohail Ikram, David P. Lee, Connor O'Brien, Joao A.C. Lima, Mohammad R. Ostovaneh, Bharath Ambale-Venkatesh, Gregory D. Lewis, Aisha Khan, Ketty Bacallao, Krystalenia Valasaki, Bangon Longsomboon, Adrian P. Gee, Sara Richman, Doris A. Taylor, Dejian Lai, Shelly L. Sayre, Judy Bettencourt, Rachel W. Vojvodic, Michelle Cohen, Lara M. Simpson, David Aguilar, Catalin Loghin, Lem Moyé, Ray F. Ebert, Barry R. Davis, Robert D. Simari

Fibroblast Growth Factor 23 and Exercise Capacity in Heart Failure with Preserved Ejection Fraction.

Jasleen Ghuman, Xuan Cai, Ravi B. Patel, Sadiya S. Khan, Jonathan Hecktman, Margaret M. Redfield, Gregory D. Lewis, Sanjiv J. Shah, Myles Wolf, Tamara Isakova, Rupal Mehta

Cardiopulmonary Exercise Testing-Based Risk Stratification in the Modern Era of Advanced Heart Failure Management.

Gregory D. Lewis, Daniel A. Zlotoff

Exercise Intolerance in Heart Failure With Preserved Ejection Fraction: Arterial Stiffness and Abnormal Left Ventricular Hemodynamic Responses During Exercise

Emily K. Zern, Jennifer E. Ho, Lindsay G. Panah, Emily S. Lau, Elizabeth Liu, Robyn Farrell, John A. Sbarbaro, Mark W. Schoenike, Paul P. Pappagianopoulos, Mayooran Namasivayam, Rajeev Malhotra, Matthew Nayor, Gregory D. Lewis

Beyond the stethoscope: managing ambulatory heart failure during the COVID-19 pandemic.

Andrew S. Oseran, Maxwell Afari, Conor D. Barrett, Gregory D. Lewis, Sunu S. Thomas

Evaluation of 2 Existing Diagnostic Scores for Heart Failure With Preserved Ejection Fraction Against a Comprehensively Phenotyped Cohort.

Timothy W. Churchill, Shawn X. Li, Lisa A. Curreri, Emily K. Zern, Emily S. Lau, Elizabeth Liu, Robyn Farrell, Mark W. Shoenike, John A. Sbarbaro, Rajeev Malhotra, Matthew Nayor, Carsten Tschöpe, Rudolf A. de Boer, Gregory D. Lewis, Jennifer E. Ho

Feasibility and Consistency of Results with Deployment of an In-Line Filter for Exercise-Based Evaluations of Patients With Heart Failure During the Novel Coronavirus Disease-2019 Pandemic.

Rohan R Bhat, Mark W. Schoenike, Alyssa Kowal, Casey White, Jennifer N. Rouvina, C. Corey Hardin, Rajeev Malhotra, Gregory D. Lewis

Comprehensive Metabolic Phenotyping Refines Cardiovascular Risk in Young Adults

Venkatesh L. Murthy, Jared P. Reis, Alexander R. Pico, Robert R. Kitchen, Joao A.C. Lima, Donald M. Lloyd-Jones, Norrina B. Allen, Mercedes R. Carnethon, Gregory D. Lewis, Matthew Nayor, Ramachandran S. Vasan, Jane E. Freedman, Clary B. Clish, Ravi V. Shah

Metabolic Architecture of Acute Exercise Response in Middle-Aged Adults in the Community

Matthew Nayor, Ravi V. Shah, Patricia E. Miller, Jasmine B Blodgett, Melissa Tanguay, Alexander R. Pico, Venkatesh L. Murthy, Rajeev Malhotra, Nicholas E. Houstis, Amy Deik, Kerry A. Pierce, Kevin Bullock, Lucas Dailey, Raghava S. Velagaleti, Stephanie A. Moore, Jennifer E. Ho, Aaron L. Baggish, Clary B. Clish, Martin G. Larson, Ramachandran S. Vasan, Gregory D. Lewis

Deliberating the Diagnostic Dilemma of Heart Failure With Preserved Ejection Fraction

Jennifer E. Ho, Margaret M. Redfield, Gregory D. Lewis, Walter Paulus, Carolyn S.P. Lam

Effect of Praliciguat on Peak Rate of Oxygen Consumption in Patients with Heart Failure with Preserved Ejection Fraction: The CAPACITY HFpEF Randomized Clinical Trial

James E. Udelson, Gregory D. Lewis, Sanjiv J. Shah, Michael R. Zile, Margaret M. Redfield, John C. Burnett, John D. Parker, Jelena P. Seferovic, Phebe J. Wilson, Robert S. Mittleman, Albert T. Profy, Marvin A. Konstam

Progress Toward Cardiac Xenotransplantation

Richard N. Pierson, Jay A. Fishman, Gregory D. Lewis, David A. D'Alessandro, Margaret R. Connolly, Lars Burdorf, Joren C. Madsen, Agnes Azimzadeh

Trends in the use of hepatitis C viremic donor hearts.

Selena S. Li, Asishana A. Osho, Philicia Moonsamy, David A. D'Alessandro, Gregory D. Lewis, Mauricio A. Villavicencio, Thoralf M. Sundt, Masaki Funamoto

Cardiovascular Functional Changes in Chronic Kidney Disease: Integrative Physiology, Pathophysiology and Applications of Cardiopulmonary Exercise Testing.

Kenneth Lim, Gordon McGregor, Andrew R. Coggan, Gregory D. Lewis, Sharon M. Moe

Characterization of the Progression from Ambulatory to Hospitalized Heart Failure with Preserved Ejection Fraction

Yogesh N.V. Reddy, Masaru Obokata, Aaron D. Jones, Gregory D. Lewis, Sanjiv J. Shah, Omar F. Abou-Ezzedine, Marat Fudim, Brooke Alhanti, Lynne W. Stevenson, Margaret M. Redfield, Barry A. Borlaug

Impaired Exercise Tolerance in Heart Failure With Preserved Ejection Fraction: Quantification of Multiorgan System Reserve Capacity.

Matthew Nayor, Nicholas E. Houstis, Mayooran Namasivayam, Jennifer N. Rouvina, C. Corey Hardin, Ravi V. Shah, Jennifer E. Ho, Rajeev Malhotra, Gregory D. Lewis

Proteomic Signatures During Treatment in Different Stages of Heart Failure.

Sam A. Michelhaugh, Alexander Camacho, Nasrien E. Ibrahim, Hanna K. Gaggin, David A. D'Alessandro, Erin Coglianese, Gregory D. Lewis, James L. Januzzi

Survival After Heart Transplantation in Patients Bridged With Mechanical Circulatory Support

Philicia Moonsamy, Andrea L. Axtell, Nasrien E. Ibrahim, Masaki Funamoto, George Tolis, Gregory D. Lewis, David A. D'Alessandro, Mauricio A. Villavicencio

Sacubitril/Valsartan in Advanced Heart Failure With Reduced Ejection Fraction: Rationale and Design of the LIFE Trial.

Douglas L. Mann, Stephen J. Greene, Michael M. Givertz, Justin M. Vader, Randall C. Starling, Andrew P. Ambrosy, Palak Shah, Steven McNulty, Claudius Mahr, Divya Gupta, Margaret M. Redfield, Anuradha Lala, Gregory D. Lewis, Selma F. Mohammed, Nisha A. Gilotra, Adam D. DeVore, Eiran Z. Gorodeski, Patrice Desvigne-Nickens, Adrian F. Hernandez, Eugene Braunwald

Reply: Does PAP/CO Ratio Have a Linear Relationship?

Jennifer E. Ho, Gregory D. Lewis

Clinical and Hemodynamic Associations and Prognostic Implications of Ventilatory Efficiency in Patients With Preserved Left Ventricular Systolic Function.

Matthew Nayor, Vanessa Xanthakis, Melissa Tanguay, Jasmine B Blodgett, Ravi V. Shah, Mark W. Schoenike, John A. Sbarbaro, Robyn Farrell, Rajeev Malhotra, Nicholas E. Houstis, Raghava S. Velagaleti, Stephanie A. Moore, Aaron L. Baggish, George T. O'Connor, Jennifer E. Ho, Martin G. Larson, Ramachandran S. Vasan, Gregory D. Lewis

Association of Ascending Aortic Dilatation and Long-term Endurance Exercise Among Older Masters-Level Athletes.

Timothy W. Churchill, Erich Groezinger, Jonathan H. Kim, Garrett Loomer, J. Sawalla Guseh, Meagan M. Wasfy, Eric M. Isselbacher, Gregory D. Lewis, Rory B. Weiner, Christian Schmied, Aaron L. Baggish

Intravascular Ultrasound Pulmonary Artery Denervation to Treat Pulmonary Arterial Hypertension (TROPHY1): Multicenter, Early Feasibility Study

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Pig-to-human heart transplantation: Who goes first?

Richard N. Pierson, Lars Burdorf, Joren C. Madsen, Gregory D. Lewis, David A. D'Alessandro

Cardiovascular Functional Reserve Before and After Kidney Transplant

Kenneth Lim, Stephen M. S. Ting, Thomas Hamborg, Gordon McGregor, David Oxborough, Claudia Tomkins, Dihua Xu, Ravi Thadhani, Gregory D. Lewis, Rosemary Bland, Prithwish Banerjee, Simon Fletcher, Nithya Krishnan, Robert Higgins, Daniel Zehnder, Thomas F. Hiemstra

Does Chronotropic Incompetence in HFpEF Cause or Result From Exercise Intolerance

Van-Khue Ton, Gregory D. Lewis

Quality of life in heart failure with preserved ejection fraction: importance of obesity, functional capacity, and physical inactivity.

Yogesh N.V. Reddy, Aruna Rikhi, Masaru Obokata, Sanjiv J. Shah, Gregory D. Lewis, Omar F. Abou-Ezzedine, Shannon M. Dunlay, Steven McNulty, Hrishikesh Chakraborty, Lynne W. Stevenson, Margaret M. Redfield, Barry A. Borlaug

Adverse Renal Response to Decongestion in the Obese Phenotype of Heart Failure With Preserved Ejection Fraction.

Yogesh N.V. Reddy, Masaru Obokata, Jeffrey M. Testani, G. Michael Felker, W.H. Wilson Tang, Omar F. AbouEzzeddine, Jie Lena Sun, Hrishikesh Chakrabothy, Steven McNulty, Sanjiv J. Shah, Gregory D. Lewis, Lynne W. Stevenson, Margaret M. Redfield, Barry A. Borlaug

Are existing and emerging biomarkers associated with cardiorespiratory fitness in patients with chronic heart failure

Marat Fudim, Jacob P. Kelly, Aaron D. Jones, Omar F. AbouEzzeddine, Andrew P. Ambrosy, Stephen J. Greene, Yogesh N.V. Reddy, Kevin J. Anstrom, Brooke Alhanti, Gregory D. Lewis, Adrian F. Hernandez, G. Michael Felker

Rationale and design for a multicenter, randomized, double-blind, placebo-controlled, phase 2 study evaluating the safety and efficacy of the soluble guanylate cyclase stimulator praliciguat over 12 weeks in patients with heart failure with preserved ejection fraction (CAPACITY HFpEF).

James E. Udelson, Gregory D. Lewis, Sanjiv J. Shah, Michael R. Zile, Margaret M. Redfield, John C. Burnett, Robert S. Mittleman, Albert T. Profy, Jelena P. Seferovic, David S. Reasner, Marvin A. Konstam

Sex Differences in Exercise Capacity and Quality of Life in Heart Failure With Preserved Ejection Fraction: A Secondary Analysis of the RELAX and NEAT-HFpEF Trials

Michael C. Honigberg, Emily S. Lau, Aaron D. Jones, Adrian Coles, Margaret M. Redfield, Gregory D. Lewis, Michael M. Givertz

Polygenic Risk, Fitness, and Obesity in the Coronary Artery Risk Development in Young Adults (CARDIA) Study

Venkatesh L. Murthy, Rui Xia, Abigail S. Baldridge, Mercedes R. Carnethon, Stephen Sidney, Claude Bouchard, Mark A. Sarzynski, Joao A.C. Lima, Gregory D. Lewis, Sanjiv J. Shah, Myriam Fornage, Ravi V. Shah

Exercise Pulmonary Hypertension Predicts Clinical Outcomes in Patients With Dyspnea on Effort.

Jennifer E. Ho, Emily K. Zern, Emily S. Lau, Luke Wooster, Cole S. Bailey, Thomas F Cunningham, Aaron S. Eisman, Kathryn M. Hardin, Robyn Farrell, John A. Sbarbaro, Mark W. Schoenike, Nicholas E. Houstis, Aaron L. Baggish, Ravi V. Shah, Matthew Nayor, Rajeev Malhotra, Gregory D. Lewis

Sex Differences in Cardiometabolic Traits and Determinants of Exercise Capacity in Heart Failure With Preserved Ejection Fraction

Emily S. Lau, Thomas F Cunningham, Kathryn M. Hardin, Elizabeth Liu, Rajeev Malhotra, Matthew Nayor, Gregory D. Lewis, Jennifer E. Ho

Baseline Characteristics of the VANISH Cohort

Anna Axelsson Raja, Ling Shi, Sharlene M. Day, Mark W. Russell, Kenneth G. Zahka, Harry M. Lever, Steven D. Colan, Renee Margossian, E Kevin Hall, Jason R Becker, John L. Jefferies, Amit R. Patel, Lubna Choudhury, Anne M. Murphy, Charles E. Canter, Richard G. Bach, Matthew R.G. Taylor, Luisa Mestroni, Matthew T. Wheeler, Lee Benson, Anjali T. Owens, Joseph W. Rossano, Kimberly Y. Lin, Elfriede Pahl, Alexandre C. Pereira, Henning Bundgaard, Gregory D. Lewis, Jose D. Vargas, Allison L. Cirino, John J.V. McMurray, Calum A. MacRae, Scott D. Solomon, John Orav, Eugene Braunwald, Carolyn Y. Ho

Orthotopic heart transplant rejection in association with immunomodulatory therapy for AL amyloidosis: A case series and review of the literature.

David A. Qualls, Gregory D. Lewis, Vaishali Sanchorawala, Andrew Staron

Differential Clinical Profiles, Exercise Responses, and Outcomes Associated With Existing HFpEF Definitions.

Jennifer E. Ho, Emily K. Zern, Luke Wooster, Cole S. Bailey, Thomas F Cunningham, Aaron S. Eisman, Kathryn M. Hardin, Giovanna A. Zampierollo, Petr Jarolim, Paul P. Pappagianopoulos, Rajeev Malhotra, Matthew Nayor, Gregory D. Lewis

Pre-emptive pangenotypic direct acting antiviral therapy in donor HCV-positive to recipient HCV-negative heart transplantation: an open-label study

Emily D. Bethea, Kerry Gaj, Jenna L. Gustafson, Andrea L. Axtell, T Lebeis, Mark W. Schoenike, Karen Turvey, Erin Coglianese, Sunu S. Thomas, Christopher Newton-Cheh, Nasrien E. Ibrahim, William D. Carlson, Jennifer E. Ho, Ravi V. Shah, Matthew Nayor, T. Gift, Sarah Shao, Amanda Dugal, James F. Markmann, Nahel Elias, Heidi Yeh, Karin L. Andersson, Daniel Pratt, Irun Bhan, Kassem Safa, Jay A. Fishman, Camille N. Kotton, Paul Myoung, Mauricio A. Villavicencio, David A. D'Alessandro, Raymond T. Chung, Gregory D. Lewis

Characterization of the Obese Phenotype of Heart Failure With Preserved Ejection Fraction: A RELAX Trial Ancillary Study

Yogesh N.V. Reddy, Gregory D. Lewis, Sanjiv J. Shah, Masaru Obokata, Omar F. Abou-Ezzedine, Marat Fudim, Jie Lena Sun, Hrishikesh Chakraborty, Steven McNulty, Martin M. LeWinter, Douglas L. Mann, Lynne W. Stevenson, Margaret M. Redfield, Barry A. Borlaug

Case 20-2019: A 52-Year-Old Woman with Fever and Rash after Heart Transplantation.

Michael G. Ison, T Lebeis, Nicolas Barros, Gregory D. Lewis, Lucas R. Massoth

Diagnostic Yield of Customized Exercise Provocation Following Routine Testing

Timothy W. Churchill, Michael Disanto, Tamanna Singh, Erich Groezinger, Garrett Loomer, Miranda Contursi, Milena DiCarli, Jennifer Michaud-Finch, Katie Morganti Stewart, Adolph M. Hutter, Gregory D. Lewis, Rory B. Weiner, Aaron L. Baggish, Meagan M. Wasfy

Reoperative sternotomy is associated with increased early mortality after cardiac transplantation

Andrea L. Axtell, Amy G. Fiedler, Gregory D. Lewis, Serguei Melnitchouk, George Tolis, David A. D'Alessandro, Mauricio A. Villavicencio

The Upsurge in Exercise Hemodynamic Measurements in Heart Failure With Preserved Ejection Fraction.

Gregory D. Lewis, Nicholas E. Houstis

Identifying responders to oral iron supplementation in heart failure with a reduced ejection fraction: a post-hoc analysis of the IRONOUT-HF trial.

Andrew P. Ambrosy, Gregory D. Lewis, Rajeev Malhotra, Aaron D. Jones, Stephen J. Greene, Marat Fudim, Adrian Coles, Javed Butler, Abhinav Sharma, Adrian F. Hernandez, Robert J. Mentz

Circulating MicroRNAs: New Avenues for Heart Failure Classification?

Ravi V. Shah, Saumya Das, Gregory D. Lewis

The effect of donor age on posttransplant mortality in a cohort of adult cardiac transplant recipients aged 18-45.

Andrea L. Axtell, Amy G. Fiedler, David C. Chang, Heidi Yeh, Gregory D. Lewis, Mauricio A. Villavicencio, David A. D'Alessandro

Metabolite Profiles of Healthy Aging Index Are Associated With Cardiovascular Disease in African Americans: The Health, Aging, and Body Composition Study.

Ashish Yeri, Rachel A. Murphy, Megan M Marron, Clary B. Clish, Tamara B. Harris, Gregory D. Lewis, Anne B. Newman, Venkatesh L. Murthy, Ravi V. Shah

Effect of Inorganic Nitrite vs Placebo on Exercise Capacity Among Patients With Heart Failure With Preserved Ejection Fraction: The INDIE-HFpEF Randomized Clinical Trial.

Barry A. Borlaug, Kevin J. Anstrom, Gregory D. Lewis, Sanjiv J. Shah, James A. Levine, Gabe A. Koepp, Michael M. Givertz, G. Michael Felker, Martin M. LeWinter, Douglas L. Mann, Kenneth B. Margulies, Andrew L. Smith, W.H. Wilson Tang, David J. Whellan, Horng H. Chen, Victor G. Davila-Roman, Steven McNulty, Patrice Desvigne-Nickens, Adrian F. Hernandez, Eugene Braunwald, Margaret M. Redfield

Associations of Circulating Extracellular RNAs With Myocardial Remodeling and Heart Failure.

Ravi V. Shah, Jian Rong, Martin G. Larson, Ashish Yeri, Olivia Ziegler, Kahraman Tanriverdi, Venkatesh L. Murthy, Xiaojun Liu, Chunyang Xiao, Alexander R. Pico, Tianxiao Huan, Daniel Levy, Gregory D. Lewis, Anthony Rosenzweig, Ramachandran S. Vasan, Saumya Das, Jane E. Freedman

Heart Failure With Preserved Ejection Fraction Expert Panel Report: Current Controversies and Implications for Clinical Trials

Kishan S. Parikh, Kavita Sharma, Mona Fiuzat, Howard K. Surks, Jyothis T. George, Narimon Honarpour, Christopher Depre, Patrice Desvigne-Nickens, Richard Nkulikiyinka, Gregory D. Lewis, Mardi Gomberg-Maitland, Christopher M. O'Connor, Norman Stockbridge, Robert M. Califf, Marvin A. Konstam, James L. Januzzi, Scott D. Solomon, Barry A. Borlaug, Sanjiv J. Shah, Margaret M. Redfield, G. Michael Felker

Impaired right ventricular reserve predicts adverse cardiac outcomes in adults with congenital right heart disease.

Doreen DeFaria Yeh, Ada C. Stefanescu Schmidt, Aaron S. Eisman, John D Serfas, Mariam Naqvi, Mohamed A. Youniss, Aaron D Ryfa, Asaad Khan, Lucy Safi, Sara Tabtabai, Ami B. Bhatt, Gregory D. Lewis

Pulmonary Capillary Wedge Pressure Patterns During Exercise Predict Exercise Capacity and Incident Heart Failure.

Aaron S. Eisman, Ravi V. Shah, Bishnu P. Dhakal, Paul P. Pappagianopoulos, Luke Wooster, Cole S. Bailey, Thomas F Cunningham, Kathryn M. Hardin, Aaron L. Baggish, Jennifer E. Ho, Rajeev Malhotra, Gregory D. Lewis

Cardiovascular response to prescribed detraining among recreational athletes.

Charles R. Pedlar, Marcel Brown, Rob Shave, James M. Otto, Aimee L. Drane, Jennifer Michaud-Finch, Miranda Contursi, Meagan M. Wasfy, Adolph M. Hutter, Michael H. Picard, Gregory D. Lewis, Aaron L. Baggish

Post-Exercise Oxygen Uptake Recovery Delay: A Novel Index of Impaired Cardiac Reserve Capacity in Heart Failure.

Cole S. Bailey, Luke Wooster, Mary D. Buswell, Sarvagna Patel, Paul P. Pappagianopoulos, Kristian Bakken, Casey White, Melissa Tanguay, Jasmine B Blodgett, Aaron L. Baggish, Rajeev Malhotra, Gregory D. Lewis

Relative Impairments in Hemodynamic Exercise Reserve Parameters in Heart Failure With Preserved Ejection Fraction: A Study-Level Pooled Analysis

Ambarish Pandey, Rohan Khera, Bryan Park, Mark J. Haykowsky, Barry A. Borlaug, Gregory D. Lewis, Dalane W. Kitzman, Javed Butler, Jarett D. Berry

Exercise intolerance in heart failure with preserved ejection fraction: Diagnosing and ranking Its causes using personalized O 2 pathway analysis

Nicholas E. Houstis, Aaron S. Eisman, Paul P. Pappagianopoulos, Luke Wooster, Cole S. Bailey, Peter D. Wagner, Gregory D. Lewis

Myocardial Metabolism in Endurance Exercise-Induced Left Ventricular Hypertrophy.

Meagan M. Wasfy, Courtney F. Bibbo, Marcel Brown, James Deluca, Francis Wang, Brant Berkstresser, Rory B. Weiner, Gregory D. Lewis, Adolph M. Hutter, Michael H. Picard, Marcelo F. Di Carli, Aaron L. Baggish

Small RNA-seq during acute maximal exercise reveal RNAs involved in vascular inflammation and cardiometabolic health: brief report

Ravi V. Shah, Ashish Yeri, Avash Das, Amanda Courtright-Lim, Olivia Ziegler, Ernest V. Gervino, J. Ocel, Pablo Quintero Pinzon, Luke Wooster, Cole Shields Bailey, Kahraman Tanriverdi, Lea M. Beaulieu, Jane E. Freedman, Ionita Ghiran, Gregory D. Lewis, Kendall Van Keuren-Jensen, Saumya Das

Cardiopulmonary Exercise Testing Reflects Improved Exercise Capacity in Response to Treatment in Morquio A Patients: Results of a 52-Week Pilot Study of Two Different Doses of Elosulfase Alfa.

Kenneth I. Berger, Barbara K. Burton, Gregory D. Lewis, Mark A. Tarnopolsky, Paul Harmatz, John J. Mitchell, Nicole Muschol, Simon Jones, V. Reid Sutton, Gregory M. Pastores, Heather Lau, Rebecca Sparkes, Adam J. Shaywitz

An official European Respiratory Society statement: pulmonary haemodynamics during exercise

Gabor Kovacs, Philippe Hervé, Joan Albert Barberà, Ari Chaouat, Denis Chemla, Robin Condliffe, Gilles Garcia, Ekkehard Grünig, Luke Howard, Marc Humbert, Edmund M.T. Lau, Pierantonio Laveneziana, Gregory D. Lewis, Robert Naeije, Andrew J. Peacock, Stephan Rosenkranz, Rajeev Saggar, Silvia Ulrich, Dario Vizza, Anton Vonk Noordegraaf, Horst Olschewski

Submaximal Blood Pressure Responses to Exercise in Young Adulthood and Long-Term Cardiovascular Health

Ravi V. Shah, Venkatesh L. Murthy, Laura A. Colangelo, Jared P. Reis, J. Jeffrey Carr, Stephen Sidney, Juned Siddique, Cora E. Lewis, Joao A.C. Lima, Gregory D. Lewis, Cardia Investigators

Enhancing insights into pulmonary vascular disease through a precision medicine approach: A joint nhlbi-cardiovascular medical research and education fund workshop report

John H. Newman, Stuart Rich, Steven H. Abman, John H. Alexander, John Barnard, Gerald J. Beck, Raymond L. Benza, Todd M. Bull, Stephen Y. Chan, Hyung J. Chun, Declan Doogan, Jocelyn Dupuis, Serpil C. Erzurum, Robert P. Frantz, Mark W. Geraci, Hunter Gillies, Mark T. Gladwin, Michael P. Gray, Anna R. Hemnes, Roy S. Herbst, Adrian F. Hernandez, Nicholas S. Hill, Evelyn M. Horn, Kendall S. Hunter, Zhi-Cheng Jing, Roger A. Johns, Sanjay Kaul, Steven M. Kawut, Tim Lahm, Jane A. Leopold, Greg D. Lewis, Stephen C. Mathai, Vallerie V. McLaughlin, Evangelos D. Michelakis, Steven D. Nathan, William C. Nichols, Grier P. Page, Marlene Rabinovitch, Jonathan D. Rich, Franz Rischard, Sharon Rounds, Sanjiv J. Shah, Victor F. Tapson, Naomi Lowy, Norman Stockbridge, Gail Weinmann, Lei Xiao

Effect of Oral Iron Repletion on Exercise Capacity in Patients With Heart Failure With Reduced Ejection Fraction and Iron Deficiency: The IRONOUT HF Randomized Clinical Trial.

Gregory D. Lewis, Rajeev Malhotra, Adrian F. Hernandez, Steven McNulty, Andrew L. Smith, G. Michael Felker, W.H. Wilson Tang, Shane J. LaRue, Margaret M. Redfield, Marc J. Semigran, Michael M. Givertz, Peter Van Buren, David J. Whellan, Kevin J. Anstrom, Monica R. Shah, Patrice Desvigne-Nickens, Javed Butler, Eugene Braunwald

INDIE-HFpEF (Inorganic Nitrite Delivery to Improve Exercise Capacity in Heart Failure with Preserved Ejection Fraction): Rationale and Design

Yogesh N.V. Reddy, Gregory D. Lewis, Sanjiv J. Shah, Martin M. LeWinter, Marc J. Semigran, Victor G. Davila-Roman, Kevin J. Anstrom, Adrian F. Hernandez, Eugene Braunwald, Margaret M. Redfield, Barry A. Borlaug

The Authors Reply.

Jeffrey Lin, Francis Wang, Rory B Weiner, James R DeLuca, Meagan M Wasfy, Brant Berkstresser, Gregory D Lewis, Adolph M Hutter Jr, Michael H Picard, Aaron L Baggish

Impaired left ventricular global longitudinal strain in patients with heart failure with preserved ejection fraction: insights from the RELAX trial.

Adam D. DeVore, Steven McNulty, Fawaz Alenezi, Mads Ersbøll, Justin M. Vader, Jae K. Oh, Grace Lin, Margaret M. Redfield, Gregory D. Lewis, Marc J. Semigran, Kevin J. Anstrom, Adrian F. Hernandez, Eric J. Velazquez

Topical Polymyxin‐Trimethoprim Prophylaxis May Decrease the Incidence of Driveline Infections in Patients With Continuous‐Flow Left Ventricular Assist Devices

Marlene L. Durand, Stephanie Ennis, Joshua N. Baker, Janice M. Camuso, Kathleen M. McEachern, Camille N. Kotton, Gregory D. Lewis, Jose Manuel Perez Garcia, Thomas E. MacGillivray

Abnormal heart-rate response during cardiopulmonary exercise testing identifies cardiac dysfunction in symptomatic patients with non-obstructive coronary artery disease.

Sundeep Chaudhry, Naresh Kumar, Hushyar Behbahani, Akshay Bagai, Binoy K. Singh, Nick Menasco, Gregory D. Lewis, Laurence S. Sperling, Jonathan Myers

Predicting Success: Left Ventricular Assist Device Explantation Evaluation Protocol Using Comprehensive Cardiopulmonary Exercise Testing.

Johannes Steiner, Stephanie Wiafe, Janice M. Camuso, Katherine Milley, Luke Wooster, Cole S. Bailey, Sunu S. Thomas, David A. D'Alessandro, Jose Manuel Perez Garcia, Gregory D. Lewis

Cardiovascular Risk and Disease Among Masters Endurance Athletes: Insights from the Boston MASTER (Masters Athletes Survey To Evaluate Risk) Initiative.

Shapero K, Deluca J, Contursi M, Wasfy M, Weiner RB, Lewis GD, Hutter A, Baggish AL

Blood Pressure and LV Remodeling Among American-Style Football Players

Jeffrey Lin, Francis Wang, Rory B. Weiner, James Deluca, Meagan M. Wasfy, Brant Berkstresser, Gregory D. Lewis, Adolph M. Hutter, Michael H. Picard, Aaron L. Baggish

Cardiovascular Risk and Disease Among Masters Endurance Athletes: Insights from the Boston MASTER (Masters Athletes Survey To Evaluate Risk) Initiative.

Kayle Shapero, James Deluca, Miranda Contursi, Meagan Wasfy, Rory B Weiner, Gregory D Lewis, Adolph Hutter, Aaron L Baggish

Left Atrial Structure and Function in Heart Failure with Preserved Ejection Fraction: A RELAX Substudy.

Siddique Abbasi, Ravi V. Shah, Steven McNulty, Adrian F. Hernandez, Marc J. Semigran, Gregory D. Lewis, Michael Jerosch-Herold, Raymond J. Kim, Margaret M. Redfield, Raymond Y. Kwong

Cardiopulmonary Exercise Testing in Heart Failure.

Rajeev Malhotra, Kristian Bakken, Emilia D'Elia, Gregory D. Lewis

Continuous Non-invasive Cardiac Output Monitoring During Exercise: Validation of Electrical Cardiometry with Fick and Thermodilution Methods

Y.H. Liu, B.P. Dhakal, C. Keesakul, Robert M. Kacmarek, G.D. Lewis, Y. Jiang

Pulmonary Vascular Distensibility Predicts Pulmonary Hypertension Severity, Exercise Capacity, and Survival in Heart Failure

Rajeev Malhotra, Bishnu P. Dhakal, Aaron S. Eisman, Paul P. Pappagianopoulos, Ashley E Dress, Rory B. Weiner, Aaron L. Baggish, Marc J. Semigran, Gregory D. Lewis

Submaximal Exercise Systolic Blood Pressure and Heart Rate at 20 Years of Follow-up: Correlates in the Framingham Heart Study.

Nicole L. Spartano, Asya Lyass, Martin G. Larson, Gregory D. Lewis, Ramachandran S. Vasan

Oral Iron Therapy for Heart Failure With Reduced Ejection Fraction: Design and Rationale for Oral Iron Repletion Effects on Oxygen Uptake in Heart Failure

Gregory D. Lewis, Marc J. Semigran, Michael M. Givertz, Rajeev Malhotra, Kevin J. Anstrom, Adrian F. Hernandez, Monica R. Shah, Eugene Braunwald

Heart Rate Modulation in Heart Failure: Time to Slow Down?

Neal A. Chatterjee, Gregory D. Lewis

Midlife exercise blood pressure, heart rate, and fitness relate to brain volume 2 decades later.

Nicole L. Spartano, Jayandra J. Himali, Alexa S. Beiser, Gregory D. Lewis, Charles DeCarli, Ramachandran S. Vasan, Sudha Seshadri

Impaired Right Ventricular–Pulmonary Arterial Coupling and Effect of Sildenafil in Heart Failure With Preserved Ejection Fraction An Ancillary Analysis From the Phosphodiesterase-5 Inhibition to Improve Clinical Status And Exercise Capacity in Diastolic Heart Failure (RELAX) Trial

Imad Hussain, Selma F. Mohammed, Paul R. Forfia, Gregory D. Lewis, Barry A. Borlaug, Dianne Gallup, Margaret M. Redfield

Exercise oscillatory ventilation: Mechanisms and prognostic significance

Bishnu P. Dhakal, Gregory D. Lewis

Fatty Acid Metabolic Defects and Right Ventricular Lipotoxicity in Human Pulmonary Arterial Hypertension

Evan L. Brittain, Joshua P. Fessel, He Zhu, Niki Penner, M. Wade Calcutt, James West, Mitch Funke, Gregory D. Lewis, Robert E. Gerszten, Rizwan Hamid, Meredith E. Pugh, Eric D. Austin, John H. Newman, Anna R. Hemnes

Elevated pulmonary arterial and systemic plasma aldosterone levels associate with impaired cardiac reserve capacity during exercise in left ventricular systolic heart failure patients: A pilot study.

Bradley A. Maron, Thomas E. Stephens, Laurie A. Farrell, William M. Oldham, Joseph Loscalzo, Jane A. Leopold, Gregory D. Lewis

Unexplained exertional dyspnea caused by low ventricular filling pressures: results from clinical invasive cardiopulmonary exercise testing

William M. Oldham, Gregory D. Lewis, Alexander R. Opotowsky, Aaron B. Waxman, David M. Systrom

Response to Letter Regarding Article, "Circulating MicroRNA-30d Is Associated With Response to Cardiac Resynchronization Therapy in Heart Failure and Regulates Cardiomyocyte Apoptosis: A Translational Pilot Study".

Yonathan F. Melman, Ravi V. Shah, Kirsty Danielson, Junjie Xiao, Bridget Simonson, Andreas S. Barth, Khalid Chakir, Gregory D. Lewis, Zachary R Lavender, Quynh A. Truong, André G. Kléber, Ranendra K. Das, Anthony Rosenzweig, Yaoyu E. Wang, David A. Kass, Jagmeet P. Singh, Saumya Das

Metabolic Profiling of Right Ventricular-Pulmonary Vascular Function Reveals Circulating Biomarkers of Pulmonary Hypertension

Gregory D. Lewis, Debby Ngo, Anna R. Hemnes, Laurie A. Farrell, Carly Domos, Paul P. Pappagianopoulos, Bishnu P. Dhakal, Amanda Souza, Xu Shi, Meredith E. Pugh, Arkadi Beloiartsev, Sumita Sinha, Clary B. Clish, Robert E. Gerszten

Association of Fitness in Young Adulthood With Survival and Cardiovascular Risk: The Coronary Artery Risk Development in Young Adults (CARDIA) Study

Ravi V. Shah, Venkatesh L. Murthy, Laura A. Colangelo, Jared P. Reis, Bharath Ambale Venkatesh, Ravi K. Sharma, Siddique Abbasi, David C. Goff, J. Jeffrey Carr, Jamal S. Rana, James G. Terry, Claude Bouchard, Mark A. Sarzynski, Aaron S. Eisman, Tomas G. Neilan, Saumya Das, Michael Jerosch-Herold, Cora E. Lewis, Mercedes R. Carnethon, Gregory D. Lewis, Joao A.C. Lima

Endurance Exercise-Induced Cardiac Remodeling: Not All Sports Are Created Equal.

Meagan M. Wasfy, Rory B. Weiner, Francis Wang, Brant Berkstresser, Gregory D. Lewis, James Deluca, Adolph M. Hutter, Michael H. Picard, Aaron L. Baggish

Exercise-Induced Left Ventricular Remodeling Among Competitive Athletes: A Phasic Phenomenon.

Rory B. Weiner, James Deluca, Francis Wang, Jeffrey Lin, Meagan M. Wasfy, Brant Berkstresser, Eric J. Stöhr, Rob Shave, Gregory D. Lewis, Adolph M. Hutter, Michael H. Picard, Aaron L. Baggish

Clinical Features and Outcomes in Adults With Cardiogenic Shock Supported by Extracorporeal Membrane Oxygenation

Brett J Carroll, Ravi V. Shah, Venkatesh L. Murthy, Stephen A. McCullough, Nosheen Reza, Sunu S. Thomas, Tae H. Song, Christopher Newton-Cheh, Janice M. Camuso, Tom MacGillivray, Thoralf M. Sundt, Marc J. Semigran, Gregory D. Lewis, Joshua N. Baker, Jose Manuel Perez Garcia

Safety and physiological effects of two different doses of elosulfase alfa in patients with morquio a syndrome: A randomized, double‐blind, pilot study

Barbara K. Burton, Kenneth I. Berger, Gregory D. Lewis, Mark A. Tarnopolsky, Marsha Treadwell, John J. Mitchell, Nicole Muschol, Simon Jones, V. Reid Sutton, Gregory M. Pastores, Heather Lau, Rebecca Sparkes, Fred Genter, Adam J. Shaywitz, Paul Harmatz

Pulmonary vascular response patterns during exercise in interstitial lung disease

Luiza Helena Degani-Costa, Barbara L. LeVarge, Subba R. Digumarthy, Aaron S. Eisman, R. Scott Harris, Gregory D. Lewis

Repletion of Iron Stores With the Use of Oral Iron Supplementation in Patients With Systolic Heart Failure

Emily Niehaus, Rajeev Malhotra, Diane Cocca-Spofford, Marc J. Semigran, Gregory D. Lewis

Response to Letter Regarding Article, “Effects of Sildenafil on Ventricular and Vascular Function in Heart Failure With Preserved Ejection Fraction”

Barry A. Borlaug, Horng Chen, Grace Lin, Margaret M. Redfield, Gregory D. Lewis, Marc J. Semigran, Steven McNulty, Martin M. LeWinter, Anita Deswal, Kenneth B. Margulies

Circulating MicroRNA-30d is Associated with Response to Cardiac Resynchronization Therapy in Heart Failure and Regulates Cardiomyocyte Apoptosis: A Translational Pilot Study

Yonathan F. Melman, Ravi V. Shah, Kirsty Danielson, Junjie Xiao, Bridget Simonson, Andreas S. Barth, Khalid Chakir, Gregory D. Lewis, Zachary R Lavender, Quynh A. Truong, André G. Kléber, Ranendra K. Das, Anthony Rosenzweig, Yaoyu E. Wang, David A. Kass, Jagmeet P. Singh, Saumya Das

Effects of Sildenafil on Ventricular and Vascular Function in Heart Failure With Preserved Ejection Fraction

Barry A. Borlaug, Gregory D. Lewis, Steven McNulty, Marc J. Semigran, Martin M. LeWinter, Horng Chen, Grace Lin, Anita Deswal, Kenneth B. Margulies, Margaret M. Redfield

Association of hypothyroidism with adverse events in patients with heart failure receiving cardiac resynchronization therapy.

Ajay K. Sharma, Eszter M Vegh, Mary Orencole, Alexandra Miller, Dan Blendea, Stephanie A. Moore, Gregory D. Lewis, Jagmeet P. Singh, Kimberly A. Parks, E. Kevin Heist

Mechanisms of Exercise Intolerance in Heart Failure with Preserved Ejection Fraction: The Role of Abnormal Peripheral Oxygen Extraction

Bishnu P. Dhakal, Rajeev Malhotra, Ryan M. Murphy, Paul P. Pappagianopoulos, Aaron L. Baggish, Rory B. Weiner, Nicholas E. Houstis, Aaron S. Eisman, Stacyann S. Hough, Gregory D. Lewis

Exercise Oscillatory Ventilation in Patients With Fontan Physiology

Ashwin S. Nathan, Brittani Loukas, Lilamarie Moko, Fred M. Wu, Jonathan Rhodes, Rahul H. Rathod, David M. Systrom, Ana Ubeda Tikkanen, Keri M. Shafer, Gregory D. Lewis, Michael J. Landzberg, Alexander R. Opotowsky

ECG findings in competitive rowers: normative data and the prevalence of abnormalities using contemporary screening recommendations

Meagan M. Wasfy, James Deluca, Francis Wang, Brant Berkstresser, Kathryn E. Ackerman, Aaron S. Eisman, Gregory D. Lewis, Adolph M. Hutter, Rory B. Weiner, Aaron L. Baggish

Myocardial Adaptations to Recreational Marathon Training Among Middle-Aged Men

Jodi L. Zilinski, Miranda Contursi, Stephanie K. Isaacs, James Deluca, Gregory D. Lewis, Rory B. Weiner, Adolph M. Hutter, Pierre A. d’Hemecourt, Chris Troyanos, K. Sophia Dyer, Aaron L. Baggish

Characterization of pulmonary hypertension in heart failure using the diastolic pressure gradient: limitations of a solitary measurement.

Neal A. Chatterjee, Gregory D. Lewis

It Is Time to Look at Heart Failure With Preserved Ejection Fraction From the Right Side

Neal A. Chatterjee, Johannes Steiner, Gregory D. Lewis

Effect of Phosphodiesterase Inhibition on Insulin Resistance in Obese Individuals

Jennifer E. Ho, Geoffrey A. Walford, Anahita Ghorbani, Derek P. Guanaga, Bishnu P. Dhakal, Daniel I. Nathan, Emmanuel S. Buys, Jose C. Florez, Christopher Newton-Cheh, Gregory D. Lewis, Thomas J. Wang

Causes of exercise intolerance in heart failure with preserved ejection fraction: searching for consensus.

Nicholas E. Houstis, Gregory D. Lewis

The emerging role of metabolomics in the development of biomarkers for pulmonary hypertension and other cardiovascular diseases (2013 Grover Conference series)

Gregory D. Lewis

Cardiovascular Phenotype in HFpEF Patients With or Without Diabetes: A RELAX Trial Ancillary Study

Brian R. Lindman, Victor G. Davila-Roman, Douglas L. Mann, Steven McNulty, Marc J. Semigran, Gregory D. Lewis, Lisa de las Fuentes, Susan M. Joseph, Justin M. Vader, Adrian F. Hernandez, Margaret M. Redfield

Resting Ventricular-Vascular Function and Exercise Capacity in Heart Failure with Preserved Ejection Fraction: A RELAX Trial Ancillary Study

Selma F. Mohammed, Barry A. Borlaug, Steven McNulty, Gregory D. Lewis, Grace Lin, Rosita Zakeri, Marc J. Semigran, Martin M. LeWinter, Adrian F. Hernandez, Eugene Braunwald, Margaret M. Redfield

Increases in myocardial workload induced by rapid atrial pacing trigger alterations in global metabolism.

Aslan T. Turer, Gregory D. Lewis, John F. O'Sullivan, Sammy Elmariah, Jessica L. Mega, Tayo Addo, Marc S. Sabatine, James A. de Lemos, Robert E. Gerszten

Pre-Capillary Pulmonary Hypertension and Right Ventricular Dilation Predict Clinical Outcome in Cardiac Resynchronization Therapy

Neal A. Chatterjee, Gaurav A. Upadhyay, Gaurav Singal, Kimberly A. Parks, G. William Dec, Jagmeet P. Singh, Gregory D. Lewis

Usefulness of the Seattle Heart Failure Model to identify adults with congenital heart disease at high risk of poor outcome.

Ada Stefanescu, Eric A. Macklin, Elaine Lin, David M. Dudzinski, Jacob H. Johnson, Kevin Kennedy, Daniel Jacoby, Doreen DeFaria Yeh, Gregory D. Lewis, Robert W. Yeh, Richard R. Liberthson, George K. Lui, Ami B. Bhatt

β-Aminoisobutyric Acid Induces Browning of White Fat and Hepatic β-Oxidation and Is Inversely Correlated with Cardiometabolic Risk Factors

Lee D. Roberts, Pontus Boström, John F. O'Sullivan, Robert T. Schinzel, Gregory D. Lewis, Andre Dejam, Youn-Kyoung Lee, Melinda J. Palma, Sondra Calhoun, Anastasia Georgiadi, Ming-Huei Chen, Vasan S. Ramachandran, Martin G. Larson, Claude Bouchard, Tuomo Rankinen, Amanda Souza, Clary B. Clish, Thomas J. Wang, Jennifer L. Estall, Alexander A. Soukas, Chad A. Cowan, Bruce M. Spiegelman, Robert E. Gerszten

Impact of Atrial Fibrillation on Exercise Capacity in Heart Failure with Preserved Ejection Fraction: A RELAX Trial Ancillary Study

Rosita Zakeri, Barry A. Borlaug, Steven McNulty, Selma F. Mohammed, Gregory D. Lewis, Marc J. Semigran, Anita Deswal, Martin M. LeWinter, Adrian F. Hernandez, Eugene Braunwald, Margaret M. Redfield

Pulmonary Vascular Hemodynamic Response to Exercise in Cardiopulmonary Diseases

Gregory D. Lewis, Eduardo Bossone, Robert Naeije, Ekkehard Grünig, Rajeev Saggar, Patrizio Lancellotti, Stefano Ghio, Janos Varga, Sanjay Rajagopalan, Ronald J. Oudiz, Melvyn Rubenfire

A diabetes-predictive amino acid score and future cardiovascular disease

Martin Magnusson, Gregory D. Lewis, Ulrika Ericson, Marju Orho-Melander, Bo Hedblad, Gunnar Engström, Gerd Östling, Clary B. Clish, Thomas J. Wang, Robert E. Gerszten, Olle Melander

Prolonged Mean Vo2 Response Time in Systolic Heart Failure An Indicator of Impaired Right Ventricular-Pulmonary Vascular Function

Neal A. Chatterjee, Ryan M. Murphy, Rajeev Malhotra, Bishnu P. Dhakal, Aaron L. Baggish, Paul P. Pappagianopoulos, Stacyann S. Hough, Marc J. Semigran, Gregory D. Lewis

Effect of phosphodiesterase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction: A randomized clinical trial

Margaret M. Redfield, Horng H. Chen, Barry A. Borlaug, Marc J. Semigran, Kerry L. Lee, Gregory D. Lewis, Martin M. LeWinter, Jean L. Rouleau, David A. Bull, Douglas L. Mann, Anita Deswal, Lynne W. Stevenson, Michael M. Givertz Elizabeth O Ofili, Christopher M. O'Connor, G. Michael Felker, Steven R. Goldsmith, Bradley A. Bart, Steven McNulty, Jenny C. Ibarra, Grace Lin, Jae K. Oh, Manesh R. Patel, Raymond J. Kim, Russell P. Tracy, Eric J. Velazquez, Kevin J. Anstrom, Adrian F. Hernandez, Alice M. Mascette, Eugene Braunwald

Exercise-induced pulmonary hypertension: physiological basis and methodological concerns.

Robert Naeije, Rebecca Vanderpool, Bishnu P. Dhakal, Rajeev Saggar, Rajan Saggar, Jean-Luc Vachiery, Gregory D. Lewis

Hemodynamic responses to rapid saline loading: the impact of age, sex, and heart failure

Naoki Fujimoto, Barry A. Borlaug, Gregory D. Lewis, Jeffrey L. Hastings, Keri M. Shafer, Paul S. Bhella, Graeme Carrick-Ranson, Benjamin D. Levine

Biomarkers in acutely decompensated heart failure with preserved or reduced ejection fraction

Kalkidan Bishu, Anita Deswal, Horng H. Chen, Martin M. LeWinter, Gregory D. Lewis, Marc J. Semigran, Barry A. Borlaug, Steven McNulty, Adrian F. Hernandez, Eugene Braunwald, Margaret M. Redfield

Exercise Oscillatory Ventilation in Heart Failure

Bishnu P. Dhakal, Ryan M. Murphy, Gregory D. Lewis

Multidisciplinary care of patients receiving cardiac resynchronization therapy is associated with improved clinical outcomes

Robert K. Altman, Kimberly A. Parks, Christopher L. Schlett, Mary Orencole, Mi-Young Park, Quynh A. Truong, Peerawut Deeprasertkul, Stephanie A. Moore, Conor D. Barrett, Gregory D. Lewis, Saumya Das, Gaurav A. Upadhyay, E. Kevin Heist, Michael H. Picard, Jagmeet P. Singh

World Health Organization Pulmonary Hypertension group 2: pulmonary hypertension due to left heart disease in the adult--a summary statement from the Pulmonary Hypertension Council of the International Society for Heart and Lung Transplantation.

James C. Fang, Teresa DeMarco, Michael M. Givertz, Barry A. Borlaug, Gregory D. Lewis, J. Eduardo Rame, Mardi Gomberg-Maitland, Srinivas Murali, Robert P. Frantz, Dana McGlothlin, Evelyn M. Horn, Raymond L. Benza

Regression of “Gray Zone” Exercise-Induced Concentric Left Ventricular Hypertrophy During Prescribed Detraining

Rory B. Weiner, Francis Wang, Brant Berkstresser, Jonathan H. Kim, Thomas J. Wang, Gregory D. Lewis, Adolph M. Hutter, Michael H. Picard, Aaron L. Baggish

Metabolite Profiling Identifies Pathways Associated With Metabolic Risk in Humans

Susan Cheng, Eugene P. Rhee, Martin G. Larson, Gregory D. Lewis, Elizabeth L. McCabe, Dongxiao Shen, Melinda J. Palma, Lee D. Roberts, Andre Dejam, Amanda Souza, Amy Deik, Martin Magnusson, Caroline S. Fox, Christopher J. O'Donnell, Ramachandran S. Vasan, Olle Melander, Clary B. Clish, Robert E. Gerszten, Thomas J. Wang

Pulmonary vascular responses to exercise: a haemodynamic observation

Rajan Saggar, Gregory D. Lewis, David M. Systrom, Hunter C. Champion, Robert Naeije

Use of Amino-Terminal Pro–B-Type Natriuretic Peptide to Guide Outpatient Therapy of Patients With Chronic Left Ventricular Systolic Dysfunction

James L. Januzzi, Shafiq U. Rehman, Asim A. Mohammed, Anju Bhardwaj, Linda Barajas, Justine Barajas, Han Na Kim, Aaron L. Baggish, Rory B. Weiner, Annabel Chen-Tournoux, Jane E. Marshall, Stephanie A. Moore, William D. Carlson, Gregory D. Lewis, Jordan T. Shin, Dorothy Sullivan, Kimberly A. Parks, Thomas J. Wang, Shawn A. Gregory, Shanmugam Uthamalingam, Marc J. Semigran

Exercise Oscillatory Ventilation in Systolic Heart Failure An Indicator of Impaired Hemodynamic Response to Exercise

Ryan M. Murphy, Ravi V. Shah, Rajeev Malhotra, Paul P. Pappagianopoulos, Stacyann S. Hough, David M. Systrom, Marc J. Semigran, Gregory D. Lewis

What Is the Prognostic Significance of Pulmonary Hypertension in Heart Failure

Neal A. Chatterjee, Gregory D. Lewis

Dynamic regulation of circulating microRNA during acute exhaustive exercise and sustained aerobic exercise training

Aaron L. Baggish, Andrew E. Hale, Rory B. Weiner, Gregory D. Lewis, David M. Systrom, Francis Wang, Thomas J. Wang, Stephen Y. Chan

A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease

Terri A. Addona, Xu Shi, Hasmik Keshishian, D. R. Mani, Michael Burgess, Michael A. Gillette, Karl R. Clauser, Dongxiao Shen, Gregory D. Lewis, Laurie A. Farrell, Michael A. Fifer, Marc S. Sabatine, Robert E. Gerszten, Steven A. Carr

Myocardial Ischemia Induced by Rapid Atrial Pacing Causes Troponin T Release Detectable by a Highly Sensitive Assay : Insights From a Coronary Sinus Sampling Study

Aslan T. Turer, Tayo Addo, Justin L. Martin, Marc S. Sabatine, Gregory D. Lewis, Robert E. Gerszten, Ellen C. Keeley, Joaquin E. Cigarroa, Richard A. Lange, L. David Hillis, James A. de Lemos

Pulmonary Vascular Response Patterns During Exercise in Left Ventricular Systolic Dysfunction Predict Exercise Capacity and Outcomes

Gregory D. Lewis, Ryan M. Murphy, Ravi V. Shah, Paul P. Pappagianopoulos, Rajeev Malhotra, Kenneth D. Bloch, David M. Systrom, Marc J. Semigran

Vasoreactivity to inhaled nitric oxide with oxygen predicts long-term survival in pulmonary arterial hypertension

Rajeev Malhotra, Dean R. Hess, Gregory D. Lewis, Kenneth D. Bloch, Aaron B. Waxman, Marc J. Semigran

Metabolite profiles and the risk of developing diabetes

Thomas J. Wang, Martin G. Larson, Ramachandran S. Vasan, Susan Cheng, Eugene P. Rhee, Elizabeth L. McCabe, Gregory D. Lewis, Caroline S. Fox, Paul F. Jacques, Céline Fernandez, Christopher J. O'Donnell, Stephen A Carr, Vamsi K. Mootha, Jose C. Florez, Amanda Souza, Olle Melander, Clary B. Clish, Robert E. Gerszten

Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans

Eugene P. Rhee, Susan Cheng, Martin G. Larson, Geoffrey A. Walford, Gregory D. Lewis, Elizabeth L. McCabe, Elaine Yang, Laurie A. Farrell, Caroline S. Fox, Christopher J. O'Donnell, Steven A. Carr, Ramachandran S. Vasan, Jose C. Florez, Clary B. Clish, Thomas J. Wang, Robert E. Gerszten

The utility of cardiopulmonary exercise testing in the assessment of suspected microvascular ischemia.

Sundeep Chaudhry, Ross Arena, Karlman Wasserman, James E. Hansen, Gregory D. Lewis, Jonathan Myers, Romualdo Belardinelli, Brian D. LaBudde, Nicholas Menasco, William E. Boden

Effect of Weight Loss After Weight Loss Surgery on Plasma N-Terminal Pro-B-Type Natriuretic Peptide Levels

Annabel Chen-Tournoux, Abigail Khan, Aaron L. Baggish, Victor M. Castro, Marc J. Semigran, Elizabeth L. McCabe, George V. Moukarbel, Jason Reingold, Sofia Durrani, Gregory D. Lewis, Christopher Newton-Cheh, Marielle Scherrer-Crosbie, Lee M. Kaplan, Thomas J. Wang

The Utility of Cardiopulmonary Exercise Testing to Detect and Track Early-Stage Ischemic Heart Disease

Sundeep Chaudhry, Ross Arena, James E. Hansen, Gregory D. Lewis, Jonathan Myers, Laurence S. Sperling, Brian D. LaBudde, Karlman Wasserman

A new data mining approach for profiling and categorizing kinetic patterns of metabolic biomarkers after myocardial injury

Christian Baumgartner, Gregory D. Lewis, Michael Netzer, Bernhard Pfeifer, Robert E. Gerszten

Metabolite Profiling Identifies Markers of Uremia

Eugene P. Rhee, Amanda Souza, Laurie A. Farrell, Martin R. Pollak, Gregory D. Lewis, David J.R. Steele, Ravi Thadhani, Clary B. Clish, Anna Greka, Robert E. Gerszten

Metabolic Signatures of Exercise in Human Plasma

Gregory D. Lewis, Laurie A. Farrell, Malissa J. Wood, Maryann E. Martinovic, Zoltan Arany, Glenn C. Rowe, Amanda Souza, Susan Cheng, Elizabeth L. McCabe, Elaine Yang, Xu Shi, Rahul C. Deo, Frederick P. Roth, Aarti Asnani, Eugene P. Rhee, David M. Systrom, Marc J. Semigran, Ramachandran S. Vasan, Steven A. Carr, Thomas J. Wang, Marc S. Sabatine, Clary B. Clish, Robert E. Gerszten

Toward metabolomic signatures of cardiovascular disease.

Gregory D. Lewis, Robert E. Gerszten

Pulmonary Vascular Response Patterns to Exercise: Is there a Role for Pulmonary Arterial Pressure Assessment during Exercise in the Post-Dana Point Era?

Gregory D. Lewis

Interpreting metabolomic profiles using unbiased pathway models.

Rahul C. Deo, Luke Hunter, Gregory D. Lewis, Guillaume Paré, Ramachandran S. Vasan, Daniel I. Chasman, Thomas J. Wang, Robert E. Gerszten, Frederick P. Roth

The Role of the Pulmonary Vasculature in Heart Failure With Preserved Ejection Fraction

Gregory D. Lewis

Exercise-Induced Myocardial Ischemia Detected by Cardiopulmonary Exercise Testing

Sundeep Chaudhry, Ross Arena, Karlman Wasserman, James E. Hansen, Gregory D. Lewis, Jonathan Myers, Nicolas Chronos, William E. Boden

Determinants of Ventilatory Efficiency in Heart Failure The Role of Right Ventricular Performance and Pulmonary Vascular Tone

Gregory D. Lewis, Ravi V. Shah, Paul P. Pappagianopolas, David M. Systrom, Marc J. Semigran

Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury

Gregory D. Lewis, Ru Wei, Emerson Liu, Elaine Yang, Xu Shi, Maryann E. Martinovic, Laurie A. Farrell, Aarti Asnani, Marcoli Cyrille, Arvind Ramanathan, Oded Shaham, Gabriel F. Berriz, Patricia A. Lowry, Igor F. Palacios, Murat Tasan, Frederick P. Roth, Jiangyong Min, Christian Baumgartner, Hasmik Keshishian, Terri Addona, Vamsi K. Mootha, Anthony Rosenzweig, Steven A. Carr, Michael A. Fifer, Marc S. Sabatine, Robert E. Gerszten

Application of Metabolomics to Cardiovascular Biomarker and Pathway Discovery

Gregory D. Lewis, Aarti Asnani, Robert E. Gerszten

Exercise blood pressure and the risk of incident cardiovascular disease (from the Framingham Heart Study).

Gregory D. Lewis, Philimon Gona, Martin G. Larson, Jonathan F. Plehn, Emelia J. Benjamin, Christopher J. O'Donnell, Daniel Levy, Ramachandran S. Vasan, Thomas J. Wang

Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity

Oded Shaham, Ru Wei, Thomas J. Wang, Catherine Ricciardi, Gregory D. Lewis, Ramachandran S. Vasan, Steven A. Carr, Ravi Thadhani, Robert E. Gerszten, Vamsi K. Mootha

Sildenafil Improves Exercise Capacity and Quality of Life in Patients with Systolic Heart Failure and Secondary Pulmonary Hypertension

Gregory D. Lewis, Ravi V. Shah, Khurram Shahzad, Janice M. Camuso, Paul P. Pappagianopoulos, Judy Hung, Ahmed Tawakol, Robert E. Gerszten, David M. Systrom, Kenneth D. Bloch, Marc J. Semigran

Case 8-2007: A 48-year-old man with chest pain followed by cardiac arrest

Gregory D. Lewis, Charles B. Holmes, Godtfred Holmvang, Joan R. Butterton

Sildenafil Improves Exercise Hemodynamics and Oxygen Uptake in Patients With Systolic Heart Failure

Gregory D. Lewis, Justine Lachmann, Janice M. Camuso, John J. Lepore, Jordan T. Shin, Maryann E. Martinovic, David M. Systrom, Kenneth D. Bloch, Marc J. Semigran

The emerging role for type 5 phosphodiesterase inhibition in heart failure

Gregory D. Lewis, Marc J. Semigran

Sildenafil Improves Coronary Artery Patency in a Canine Model of Platelet-Mediated Cyclic Coronary Occlusion After Thrombolysis

Gregory D. Lewis, Christian Witzke, Pedro J. Colon-Hernandez, J. Luis Guerrero, Kenneth D. Bloch, Marc J. Semigran

Type 5 phosphodiesterase inhibition in heart failure and pulmonary hypertension.

Gregory D. Lewis, Marc J. Semigran

Pulmonary thromboembolism superimposed on a congenital ventricular septal defect in a 50-year-old man inhaled nitric oxide and sildenafil to the rescue.

Gregory D. Lewis, Kenneth D. Bloch, Marc J. Semigran

NFkappaB: a pivotal transcription factor in prostate cancer metastasis to bone.

Valentine B Andela, Andrew H. Gordon, George Zotalis, Randy N. Rosier, J. Jeffrey Goater, Gregory D Lewis, Edward M. Schwarz, J. Edward Puzas, Regis J. O'Keefe

Intrathecal methylprednisolone for postherpetic neuralgia.

Lewis G

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999.

Melander A, Olsson J, Lindberg G, Salzman A, Howard T, Stang P, Lydick E, Emslie-Smith A, Boyle DIR, Evans JMM, Macdonald TM, Bain J, Sullivan F, Juhl C, Pørksen N, Sturis J, Hollingdal M, Pincus S, Veldhuis J, Dejgaard A, Schmitz O, Kristensen JS, Frandsen KB, Bayer T, Müller P, Dunning BE, Paladini S, Gutierrez C, Deacon R, Valentin M, Grunberger G, Weston WM, Patwardhan R, Rappaport EB, Sargeant LA, Wareham NJ, Khaw KT, Zethelius B, Lithell H, Hales CN, Berne C, Lakka H, Oksanen L, Tuomainen T, Kontula K, Salonen JT, Dekker JM, de Boks P, de Vegt F, Stehouwer CDA, Nijpels G, Bouter LM, Heine RJ, Bruno G, Cavallo-Perin P, Bargero G, D'Errico N, Borra M, Macchia G, Pagano G, Newton RW, Ruta DA, New JP, Wallace C, Roxburgh MA, Young RJ, Vaughan NJA, Elliott P, Brennan G, Devers M, MacAlpine R, Steinke D, Lawson DH, Decallonne B, Casteels K, Gysemans C, Bouillon R, Mathieu C, Linn T, Strate C, Schneider K, Funda DP, Jirsa M, Kozáková H, Kaas A, Kofronová O, Tlaskalová-Hogenová H, Buschard K, Wanka H, Hartmann A, Kuttler B, Rasmussen SB, Sørensen TS, Markholst H, Petersen JS, Karounos D, Dyrberg T, Mabley JG, Haskó G, Szabó C, Seissler J, Nguyen TBT, Steinbrenner H, Scherbaum WA, Cipriani R, Gabriele A, Sensi M, Guidobaldi L, Pantellini F, Cerrito MG, Scarpa S, Di Mario U, Morano S, Ceolotto G, Iori E, Baritono E, Del Prato S, Semplicini A, Trevisan R, Zerbini G, Meregalli G, Asnaghi V, Tentori F, Maestroni A, Mangili R, Marescotti C, Vedovato M, Tiengo A, Tadjieva J, Mankovsky BN, Van Aken S, Raes A, Vande Walle J, Matthys D, Craen M, Hansen HP, Lund SS, Rossing P, Jensen T, Parving H, Andersen S, Tarnow L, Hansen BV, Trautner C, Haastert B, Ennenbach N, Willich S, Tabák ÁG, Orchard TJ, Spranger J, Preissner KT, Schatz H, Pfeiffer A, Cantón A, Burgos R, Hernández C, Lecube A, Mesa J, Segura RM, Mateo C, Simó R, Fathallah L, Greene DA, Obrosova I, Gilbert RE, Kelly DJ, Cox AJ, Berka-Wilkinson JL, Taylor HR, Panagiotopoulos S, Lee V, Jerums G, Cooper ME, Hitman GA, Aganna E, Ogunkolade WB, Rema M, Deepa R, Shanthi-Rani CS, Barakat K, Kumarajeewa TR, Cassell PG, McDermott MF, Mohan V, Ways K, Bursell S, Devries T, Woodworth J, Alatorre C, King G, Aiello LP, Karisen AE, Pavlovic D, Nielsen K, Jensen J, Andersen HU, Pociot F, Mandrup-Poulsen T, Eizirik DL, Nerup J, Lortz S, Tiedge M, Lenzen S, Lally FJ, Bone AJ, Darville MI, Ho Y, Sternesjö J, Sandler S, Chen M, Schuit F, Pipeleers DG, Merezak S, Hardikar A, Hoet JJ, Remacle C, Reusens B, Bréant B, Garofano A, Czernichow P, Kubota N, Terauchi Y, Miki H, Tamemoto H, Yamauchi T, Nakano R, Komeda K, Eto K, Tobe K, Kimura S, Kadowaki T, Ide T, Murakami K, Tsunoda M, Mochizuki T, Ozanne SE, Nave BT, Wang CL, Dorling MW, Petry CJ, Koopmans SJ, van der Bent C, Que I, Radder JK, Sebokova E, Sana AK, Klimes I, Ruderman N, Morviducci L, Pastore L, Morelli S, Sagratella E, Zorretta D, Buongiomo A, Tamburrano G, Giaccari A, Martinenghi S, De Angelis GC, Ravasi F, Bifari F, Bordignon C, Falqui L, Kessler A, Dransfeld O, Sasson S, Tomas E, Zorzano A, Eckel J, Thorsby P, Rosenfalck AM, Kjems L, Hanssen KF, Madsbad S, Birkeland KI, Hamilton-Wessler M, Markussen J, Bergman RN, Melki V, Hanaire-Broutin H, Bessières-Lacombe S, Tauber J, Home PD, Lindholm A, Riis A, Rosenstock J, Schwartz S, Clark C, Edwards M, Donley D, Swift P, Mortensen HB, Lynggaard H, Hougaard P, Cull CA, Neil HAW, Frighi V, Manley SE, Holman RR, Turner RC, Steiner G, Davis WA, Weeraratna T, Bruce DG, Davis TME, Vergès B, Duvillard L, Pont F, Florentin E, Gambert P, Benko B, Ljubić S, Turk Z, Granić M, März W, Wollschläger H, Klein G, Neiss A, Wehling M, Huxtable SJ, Saker PJ, Walker M, Frayling TM, Levy JC, O'Rahilly S, Hattersley AT, McCarthy MI, Orecchio A, Giacchini A, Dominici R, Canettieri G, Trinti B, Zani M, Andreoli M, Sciacchitano S, de Silva AM, Whitecross K, Pasco J, Kotowicz M, Nicholson G, Zimmet P, Boyko EJ, Collier GR, Frittitta L, Pizzuti A, Argiolas A, Graci S, Goldfine ID, Bozzali M, Ercolino T, Costanzo B, Iacoviello L, Tassi V, Trischitta V, Wauters M, Rankinen T, Mertens I, Chagnon M, Bouchard C, Van Gaal L, Sivenius K, Valve R, Hakkarainen V, Niskanen L, Laakso M, Uusitupa M, Beridze N, Japaridze M, Kurashvili R, Dundua M, Kebuladze G, Kazakhashvili N, Offley-Shore B, Thomas B, Ghebremeskel K, Crawford M, Lowy C, Eriksson UJ, Martin Simán C, Wisse B, Gittenberger-de Groot AC, Wentzel P, Eriksson UJ, Wender-Ożegowska E, Drews K, Biczysko R, Bronisz A, Rość D, Graczykowska-Koczorowska A, Kotschy M, Sokup A, Kohnert KD, Besch W, Strese J, Frick U, Zander E, Kemer W, Škrha J, Kvasnička J, Kalvodová B, Hilgertová J, Schatteman K, Goossens F, Scharpé S, De Leeuw I, Hendriks D, Legakis IN, Panayiotou D, Mountokalakis TD, Enderle MD, Beckmann P, Balletshofer B, Rittig K, Maerker E, Volk A, Meisner C, Jacob S, Matthaei S, Häring HU, Rett K, Ueda K, Nakagawa T, Shimajiri Y, Kokawa M, Matsumoto E, Sasaki H, Sanke T, Nanjo K, McKinnon CM, Macfarlane WM, Docherty K, Furukawa N, Shirotani T, Kishikawa H, Kaneko K, Araki E, Shichiri M, Prentki M, Roduit R, Susini S, Buteau J, Ejrnæs AM, Andersen NA, Osterhoff M, Möhlig M, Ortmann J, Bikashaghi F, Mayer C, Bikashagi F, Ackermans MT, Pereira Arias AM, Bisschop PHLT, Endert E, Sauerwein HP, Romijn JA, Gastaldelli A, Baldi S, Pettiti M, Natali A, Frascerra S, Camastra S, Toschi E, Ferrannini E, Stingl H, Krssak M, Bischof MG, Krebs M, Fürnsinn C, Nowotny P, Waldhäusl W, Roden M, Neeft M, Meijer AJ, Båvenholm P, Pigon J, Efendic S, Kästenbauer T, Sauseng S, Sokol G, Auinger M, Irsigler K, Abbott CA, Carrington AL, Faragher B, Kulkarni J, Van Ross ERE, Boulton AJM, Armstrong DG, Hadi S, Nguyen HC, Harkless LB, Jirkovská A, Kasalicky P, Hosová J, Skibova J, Uccioli L, Caselli A, Giacomozzi C, Macellari V, Giurato L, Lardieri L, Menzinger G, Pham HT, Rosenblum BI, Lyons TE, Giurini JM, Smakowski P, Chrzan JS, Habershaw GM, Veves A, Foster AM, Bates M, Doxford M, Edmonds ME, Kecha O, Winkler R, Martens H, Collette J, Lefèbvre PJ, Greiner D, G

Accidental nuclear war--a post-cold war assessment.

Forrow L, Blair BG, Helfand I, Lewis G, Postol T, Sidel V, Levy BS, Abrams H, Cassel C